Cnim CONTENT OUTLINE I. BASIC SCIENCE AND INSTRUMENTATIO N A. Current Flow 1. Conduction and Insulation 2. Impedance 3. Resistance 4. Capacitance and Inductance B. Instrumentation 1. Differential Amplifiers a. Input Impedance b. Common Mode Rejection c. Polarity d. Gain/Sensitivity e. Other 2. Filters and Their Effects a. Low Frequency Filter b. High Frequency Filter c. Filter Slopes d. Digital Filter e. Notch (60 Hz) Filter 3. Analog to Digital Conversion a. Sampling Rate b. Nyquist Frequency Aliasing c. Horizontal Resolution 1. Analysis Time 2. Dwell Time d. Vertical (amplitude) Resolution 1. Size of A-D Converter 2. Amplifier Sensitivity 3. Number of Stimuli 4. Signal Averaging 5. Signal-to-Noise Ratio 6. Display Sensitivity 7. Artifact Rejection 8. Stimulus and Averaging Onset a. Pre-stimulus (negative) Delay b. Post-stimulus (positive) Delay 9. Simultaneous Averaging a. Synchronous b. Asynchronous c. Multiple Time Bases C. Anatomy of IOM Systems 1. Brain 2. Brain Stem a. Vascular Anatomy b. Neuroanatomy 3. Cranial Nerves a. Sensory b. Motor 4. Spinal Cord a. Bony Structures b. Posterior Columns c. Motor Tracts d. Spinal Circulation e. Cauda Equina f. Dermatomal Distribution 5. Peripheral Nerves 6. Evoked Potential Generators a. BAEPs b. SSEPs c. Cranial Nerve EMG d. Spinal Responses D. Basic Neurophysiology 1. Membrane Potential 2. Action Potential 3. Synaptic Potential a. Inhibitory b. Excitatory 4. Stationary Potential 5. Propagated Potential 6. Cortical/Subcortical Potential 7. Near-Field/Far-Field Potential 8. Neurons 9. Neurotransmitters a. Inhibitory b. Excitatory 10. Dipoles II. RECORDING CONCEPTS AND PREOPERATIVE FACTORS A. Electrodes 1. Types of Electrodes a. Surface b. Subdermal c. Spinal (Epidural) d. Cortical Grid e. Other 2. Location and Measurement 3. Application a. Security b. Duplicate Set 4. Impedance Measurement B. Operation of Equipment 1. Amplifiers 2. Averager 3. Audiometer 4. Auditory Stimulator a. Measurements of Click Intensity 1. Calibration 2. Hearing Level (dBHL) 9 3. Sensation Level (dBSL) 4. Peak-Equivalent Sound Pressure Level (dB pe SPL) b. Masking c. Types of Transducer 1. Standard Audiologic 2. Tubal Inserts With Stimulus Delay 3. Small Inserts Without Delay 4. Other 5. Current Stimulator a. Adequacy of Stimulus Intensity b. Types 1. Constant Current 2. Constant Voltage c. Site of Stimulation 1. Transdermal 2. Near Nerve Needle 3. Direct Cranial Nerve 4. Spinal Cord 5. Cortical d. Electrodes 1. Types 2. Monopolar vs Bipolar e. Stimulation Issues 1. Impedance of Tissue/ Shunting of Current 2. Ohm's Law and Application 3. Neurotoxicity 4. Current Density 5. Polarity f. Stimulus Parameters 1. Duration 2. Rate 3. Monophasic vs Biphasic Pulse C. BAEPs 1. Nonpathologic Factors a. Filter Effects b. Click Intensity c. Click Polarity d. Click Rate e. Masking f. Other 2. Pathologic Factors a. Hearing Deficits 1. Cochlear 2. Retrocochlear b. Lesions c. Other 3. Montages 4. Obligate Components and Measures 5. Criteria for Abnormality D. SSEPs 1. Nonpathologic Factors a. Motor/Sensory Threshold b. Adequacy of Peripheral Nerve Response c. Equalizing Peripheral Nerve Response d. Filter Effects e. Limb Temperature and Length 2. Pathologic Factors a. Peripheral Neuropathy b. Other 3. Montages 4. Obligate Components and Measures 5. Criteria for Abnormality E. Surgical Procedures and Appropriate Monitoring Procedures 1. Posterior Fossa a. BAEPs b. MN-SSEPs c. Cranial Nerves d. Electrocochleograms 2. Carotid Artery a. MN-SSEPs b. EEG c. TCD d. Cerebral Oximetry 3. Spinal Cord Lesions a. MN-SSEPs b. PTN-SSEPs c. Other 4. Scoliosis a. PTN-SSEPs b. CPN-SSEPs 5. Other Spine Procedures 6. Otolaryngology a. BAEPs b. Facial Nerve c. Electrocochleograms d. Other 7. Functional Mapping a. Sensory b. Motor 8. Electrocorticography & EEG 9. Other F. Preoperative Baseline 1. BAEPs 2. SSEPs 3. Multi-modality 4. EEG 5. Other 10 III. INTRAOPERATIVE MONITORING A. Technologist's Role in the OR 1. Relationship With Team 2. Data Description and Documentation B. Methods of Recording 1. Scalp-to-Scalp 2. Scalp-toNoncephalic 3. Spinal a. Bipolar vs Referential b. Sites 1. Interspinous Ligament 2. Spinous Process 3. Epidural 4. Cranial NerveSupplied Muscles 5. Peripheral Nerves 6. Motor Nerve Conduction 7. Myotomal a. Cervical b. Thoracic c. Lumbar d. Sacral C. Surgical Instrumentation and Equipment 1. Neurosurgical 2. Orthopaedic 3. Otolaryngology 4. Others D. Induction and Intrasurgical 1. Patient Positioning Routing of Electrodes/ Cables 2. Post-Anesthesia and Post-Positioning Recording 3. Use of Input vs Averaged Data 4. Criteria for Abnormality 5. Trending of Data a.Latencies/Interpeak Intervals/Amplitudes b. Processed EEG 1. Condensed Density Spectral Array 2. Spectral Edge 6. Train of Four Stimulation a. Recording b. Stimulation c. Uses E. Factors Affecting Waveform Resolution 1. Physiologic a. Blood Pressure, Perfusion b. Temperature c. ICP d. Oxygenation e. Ventilation f. Metabolites, Electrolyttes g. Others 2. Pharmacologic a. Types of Anesthetic Agents 1. Intravenous Agents a. Opiod Agents b. Ketamine 2. Inhalational Agents a. Halogenated b. Nitrous 3. SedativeHypnotic Drugs a. Barbiturates b. Benzodiazapi nes c. Etomidate d. Propofol e. Droperidol 4. Neuromuscular Blocking Agents a. Depolarizing b. NonDepolarizing 5. Regional Anesthesia b. Measures of Concentration c. Rate of Administration 1. Constant Infusion 2. Bolus 3. Structural a. Traction on Neural Structures b. Vascular Compromise c. Coagulation and Drilling 4. Technical a. Stimulus Parameters b. Electrodes c.Recording Parameters F. Facial Nerve Stimulation and Recording 1. Spontaneous Activity 2. Compound Muscle Action Potentials 3. Effects of Neuromuscular Blocking Agents 4. Effects of Stimulus Intensity 5. Amplitude/Intensity Function 11 G. Motor Pathway Stimulation 1. Uses 2. Stimulators a. Magnetic b. Electrical 3. Effects of Various Factors a. Halogenated Agents b. Neuromuscular Blocking Agents c. Stimulus Rate d. Stimulus Intensity H. Intraoperative Monitoring Record 1. Annotating Changes a. Blood Pressure b. Core Temperature c. Limb Temperature d. Anesthetic Agents e. Instrumentation Parameters 2. Procedure Milestones 3. Surgical Manipulations 4. Monitoring Feedback to Surgeons 5. Surgeon Response IV.SURGICAL OUTCOMES A. Preexisting Clinical Correlates B. Complications 1. Motor System 2. Sensory System 3. Auditory Pathway 4. Cranial Nerve Palsy 5. Other Neurologic Deficits C. Prevention 1. Criteria for Warning Surgeon 2. Wake-Up Test V. TROUBLESHOOTIN G A. Basic Concepts 1. Appropriate Baseline Responses 2. Communication with Surgeon and Anesthesiologist 3. Systemic vs Local Effects a. Effects of Vascular Manipulation b. Effects of Structural Manipulation B. Artifacts 1. Physiologic a. EMG b. ECG c. Other 2. Nonphysiologic a. 60 Hz b. Stimulator c. Electrode d. OR Equipment 1. Electrocautery Bipolar vs Monopolar 2. Blood Warmer 3. Humidifier 4. Fluorescent Lights 5. Microscope 6. Neurosurgical Devices 7. Pneumatic Drill 8. Cell Saver 9. CUSA 10. BAIR Hugger e. Other C. Effects on Waveform Resolution 1. Electrocautery 2. Coagulation 3. Drilling VI. SAFETY ISSUES A. Infection Control Standard 1. Universal Precautions 2. Sterile Techniques 3. Transmission Based Precautions 4. Electrode Care 5. Equipment Care B. Electrical Safety 1. Leakage Current 2. Grounding System 3. Line Isolation Monitor 4. Isolated Inputs 5. Safety Checks C. Hazards 1. Infections 2. Electrical 12 SAMPLE QUESTIONS 1. Cortical potentials will be most affected by which of the following agents? 1. Narcotics 2. Barbiturates 3. Inhalational anesthetics 4. Neuromuscular blockers 2. Which of the following is a far-field potential? 1. N20 2. P14 3. Wave I 4. Erb's point 3. Which of the following is an effect of using alternating click polarity? 1. Reduces stimulus intensity 2. Minimizes stimulus artifact 3. Increases amplitude of wave I 4. Improved signal to noise ratio 4. ANKYLOSIS 1. Foot drop 2. Wrist drop 3. Fused joint 4. Arterial occlusion 5. Grounding the stimulated limb during a SSEP procedure decreases 1. stimulus artifact. 2. stimulus intensity. 3. stimulating electrode impedances. 4. spread of stimulating current. 6. What is the MAXIMUM acceptable chassis leakage current? 1. 1 µA 2. 10 µA 3. 100 µA 4. 1000 µA Answers to sample questions: 1.3, 2.2, 3.2, 4.3, 5.1, 6.3 13