APPENDIX 2 TOPICAL ANTIMICROBIAL DRESSINGS Community Health Stockport PCT Topical Antimicrobial Wound Dressings Formulary Decisions regarding the treatment of clinically infected or critically colonised wounds must be informed by the Topical Antimicrobial Algorithm. First Line Management Product Options Wound Cleansing £ Prontosan Solution Wound cleansing solution containing Betaine and PHMB (Polyhexamethylene bigunaide) Used instead of normal saline for wound cleansing for wounds that are; MRSA positive critically colonised A 350 ml bottle can be use for up to 8 weeks. There is some evidence that soaking wounds with the product for 10 minutes may have some increase in effectiveness. No known contraindications or cautions Superficial wounds/lesions £ Inadine 10% Povidone Iodine. Only for use with low exudate wounds. Available in 5x5cm 9.5cmx9.5cm Do not use if Known iodine sensitivity. Before and after the use of radio- iodine ( until permanent healing) Patient being treated for kidney problems Patient is pregnant or breast feeding In cases of Duhring’s herpetiform dermatitis( rare skin disorder) To use with caution Must be used under medical supervision in patients with any thyroid disease In new babies and infants to the age of 6 months £ Actilite A low adherent dressing coated with antibacterial and essential oils Available in 10x10cm 10x20cm Do not use if Patient has known bee venom allergy, bee products or essential oils Possible Side Effects May cause stinging on application. This should resolve within 30 minutes. If stinging continues remove dressing Full/ Partial Thickness Wounds ££ Algivon An absorbent, non adherent antibacterial calcium alginate impregnated with Activon medical Manuka honey. Especially useful for sloughy, necrotic and malodorous wounds. May increase exudate due to mode of action Available in 5x5cm 10x10cm Do not use if Patient is sensitive to bee venom or bee products To use with caution Patient is diabetic. Blood sugars require monitoring Wounds with active blood loss Possible Side effects May cause stinging on application. This should resolve within 30 minutes. If stinging continues remove dressing ££ Iodoflex/Iodosorb Cadexomer dressing with Iodine Iodoflex Available in 5g 10g 17g Iodosorb ointment Available in 10g and 20g 3g powder sachet For wounds which producing moderate high exudate Do not use if Known iodine sensitivity. Before and after the use of radio- iodine ( until permanent healing) Patient being treated for kidney problems Patient is pregnant or breast feeding In cases of Duhring’s herpetiform dermatitis( rare skin disorder) To use with caution Must be used under medical supervision in patients with any thyroid disease In new babies and infants to the age of 6 months Should be used on dry necrotic tissue ££ Prontosan gel Useful for debriding sloughy, necrotic wounds. Helps with rehydrating devitalised tissue. No known contraindications or cautions All dressings will require some form of secondary dressings. Please ensure that the most cost effective dressing is used for this purpose Second Line Management Superficial wounds/lesions £ Atrauman Ag Non- adherent polyamide mesh wound contact layer. Impregnated with triglycerides coated with metallic silver. Effective up to 7 days. Available in 5x5cm 10x10cm 10x20cm Indications Critically colonised and infected wounds requiring a primary wound contact layer Contraindications Known sensitivity to silver ££ Aquacel Ag Absorbent fibrous dressing composed of sodium carbomethylcellulose impregnated with 1.2% ionic silver. Forms a soft gel on contact with exudate. Available in 5x5cm ●10x10cm ●15x15cm ●4x10cm ●4x20cm ●4x30cm ●2x45cm Indications Wounds producing moderate- high exudate which are critically colonised or infected Contra-indications Known sensitivity to silver ££ Suprasorb X + PHMB Bio cellulose dressing pad impregnated with broad spectrum antimicrobial (PHMB). Designed to regulate absorption and rehydration of moisture Available in 5x5cm 9x9cm 14x20cm 2x21cm Indications Light to moderately exuding wounds which are critically colonised or infected Contra-indications Known sensitivity to any of the components of the dressing Julia Walsh Tissue Viability Specialist Nurse