CURRICULUM VITAE
Chet L. Nastala, M.D., FACS
Current Practice
PRMA
Plastic, Reconstructive, and Microsurgical Associates of South
Texas
BIOGRAPHICAL
CITIZENSHIP:
United States
BIRTHDATE:
August 23, 1963
BIRTHPLACE:
Philadelphia, PA
HOME ADDRESS:
206 Elizabeth Road
San Antonio, Tx 78209
OFFICE ADDRESS:
Plastic, Reconstructive and Microsurgical Associates of South Texas
9635 Huebner Road
San Antonio, TX, 78240
OFFICE PHONE:
OFFICE FAX:
(210) 692-1181
(210) 692-7584
EMAIL ADDRESS:
WEBSITE ADDRESS:
topgolfdoc@yahoo.com
www.prma-enhance.com
SPOUSE:
Carla Jane Nastala, R.N., M.S.N.
Registered Nurse, Transplant Specialist
CHILDREN:
Madeline, Olivia, Spencer
EDUCATION and TRAINING
UNDERGRADUATE
1981-1985
Harvard University: College of Arts and Sciences, Cambridge, MA
Bachelor of Arts, 1985
Biochemical Sciences
magna cum laude
GRADUATE
1985-1989
Duke University: School of Medicine, Durham, NC
Doctor of Medicine, 1989
Kenneth Pickrell Scholarship
POST GRADUATE
1989-1992
University of Pittsburgh Medical Center, Pittsburgh, PA
Richard L. Simmons, M.D.
Chairman, Dept of Surgery
GMT I, II, III - Intern/ Resident in General Surgery
1992-1994
University of Pittsburgh Medical Center Pittsburgh, PA
Michael T. Lotze, M.D., Director, Surgical Oncology
Howard D. Edington, M.D. Plastic Surgical Oncology
Surgical Oncology and Surgical Research Fellowship
1994-1996
University of Pittsburgh Medical Center, Pittsburgh, PA
Richard L. Simmons, M.D.
Chairman, Dept of Surgery
GMT IV-V, Chief Resident in General Surgery
1996-1998
University of Pittsburgh Medical Center, Pittsburgh, PA
J. William Futrell, M.D.
Chief, Plastic Surgery
GMT VI-VII, Plastic Surgery Residency
ACADEMIC APPOINTMENTS
7/2002
Private Practice, Plastic and Reconstructive Surgery
Plastic, Reconstructive and Microsurgical Associates of South Texas
7/2001
Chief, Plastic and Reconstructive Surgery
University of Texas Health Science Center San Antonio
1/2001
Program Director, Plastic Surgery Residency
Interim Chief, Plastic and Reconstructive Surgery
University of Texas Health Science Center San Antonio
2000
Associate Program Director, Plastic Surgery Residency
University of Texas Health Science Center San Antonio
1999
University of Texas Health Science Center San Antonio
Director of Graduate and Student Education in Plastic Surgery
1998
University of Texas Health Science Center San Antonio
Assistant Professor of Plastic Surgery
Chief, Section of Aesthetic and Reconstructive Breast Surgery
BOARD CERTIFICATION
1999
American Board of Surgery
Certified February 1999, renewal 7/1/2009
1999
American Board of Plastic Surgery
Certified September 1999, renewal 9/18/2009
MEDICAL STAFF APPOINTMENTS
2001
Southwest Texas Methodist Hospital System
Plastic and Reconstructive Surgery
San Antonio, TX
2001
University Health System
Chief, Plastic and Reconstructive Surgery
San Antonio, TX
1999
Baptist Health Network
San Antonio, TX
Attending Plastic Surgeon
1999
Christus Santa Rosa Health Care System
Attending Plastic Surgeon
San Antonio, TX
1999
Audie L Murphy Veterans Administration Hospital
Chief, Section of Plastic Surgery
San Antonio, TX
1998
Audie L Murphy Veterans Administration Hospital
Director of Plastic Surgical Services
San Antonio, TX
1998
University Health System
Attending Plastic Surgeon
San Antonio, TX
PROFESSIONAL SOCIETIES
American Society of Plastic Surgeons
American Society of Plastic and Reconstructive Microsurgery
American College of Surgeons
Texas Society of Plastic Surgeons
Texas Medical Society
San Antonio International Society of Plastic Surgeons
Bexar County Medical Society
University of Pittsburgh Plastic Surgery Society
LICENSURE
1990 MD 045402 L
Pennsylvania State License
1991 BN 3062522
Federal Drug Enforcement Agency
1992
Laser Certification, University of Pittsburgh
1993
Emergency Medical Command Certification
1993
Advanced Trauma Life Support
1993
Advanced Cardiac Life Support
1994
Laser Re-Certification, University of Pittsburgh
1995
Laser Re-Certification, University of Pittsburgh
1998 K6181
Texas State License
1998 90108801
Texas Department of Public Safety
COMMITTEES
2000-2002
Young Plastic Surgeons Committee
American Society of Plastic Surgery
2000-2002
Utilization Review Committee
University Health System
San Antonio, TX
2000-2002
Chairman, Laser Committee
University Health System
San Antonio, TX
1999-2001
Operating Room Committee
University Health System
San Antonio, TX
1999-2001
UTHSCSA Cancer Committee
University of Texas Health Science Center San Antonio
1999
Laboratory Animal Services Resource Utilization
Department of Surgery
University of Texas Health Science Center San Antonio
1999
Oral Maxillofacial Surgery Chair Search Committee
University of Texas Health Science Center San Antonio
HONORS and AWARDS
1981-1985
Magna cum laude
Ada Howe Kent Scholar
Harvard College Scholarship
1985-1989
Dr. Kenneth L. Pickrell Scholarship
Duke University School of Medicine
1996
Mark Ravitch Teaching Award – Surgery
1997
Charles C. Moore School of Medicine Teaching Award - Surgery
2000
Outstanding Educator Award – Division of Plastic Surgery
UT Health Science Center, San Antonio
PUBLICATIONS
REFEREED ARTICLES
Kresh, J.Y., Nastala, C.L., Bianchi, P.C., Goldman, S.M., Brockman, S.K. The relative
buffering power of cardioplegic solutions. The Journal of Thoracic and Cardiovascular
Surgery 1987; 93(2): 309-311.
Tyler, D.S., Nastala, C.L., Lyerly, H.K., Matthews, T.J., Bolognesi, D.P., Weinhold, K.J. Direct
ADCC: Evidence for circulating antibody armed cytotoxic CD16+ NK/K cells in patients
infected with HIV-1. Surgical Forum 1988; 418-420.
Prince, A.F., Horowitz, B., Baker, L., Schulman, R.W., Ralph, H., Valinsky, J., Cundell, A.,
Brotman, B., Boehle, W., Rey, F., Piet, M., Reesink, H., Lelie, N., Tersmette, M.,
Miedems, F., Barbosa, L., Nemo, G., Nastala, C.L., Allan, J.S., Lee, D.R., Eichberg,
J.W. Failure of a human immunodeficiency virus (HIV) immune globulin to protect
chimpanzees against experimental challenge with HIV. Proc Natl Acad Sci 1988; 85:
6944-6949.
Lyerly, H.K., Skinner, M.A., Tyler, D.S., Nastala, C.L., Matthews, T.J., Bolognesi, D.P.,
Weinhold, K.J., Anti-HIV immune cytolysis is independent of viral envelope
glycosylation. Surgical Forum 1988; 420-422.
Tyler, D.S., Nastala, C.L., Stanley, D.S., Matthews, T.J., Lyerly, H.K., Bolognesi, D.P.,
Weinhold, K.J. GP120 Specific cellular cytotoxicity in HIV-1 seropositive individuals:
Evidence for circulating CD16 positive effector cells armed in vivo with cytophilic
antibody. Journal of Immunology 1989; 142: 1177-1182.
Tyler, D.S., Lyerly, H.K., Nastala, C.L., Shadduck, P.P., Fitzpatrick, K.T., Langlois, A.J.,
Moylan, J.A. Barrier protection against the human immunodeficiency virus. Current
Surgery 1989; 46: 301-304.
Tyler, D.S., Stanley, S.D., Nastala, C.L., Austin, A.A., Bartlett, J.A., Stine, K.C., Lyerly, H.K.,
Bolognesi, D.P., Weinhold, K.J. Alterations in antibody dependent cellular cytotoxicity
during the course of HIV-1 infection. Humoral and cellular defects. Journal of
Immunology 1990; 144: 3375-3384.
Nastala, C.L., Edington H., Storkus, W.J., and M.T. Lotze. Recombinant Interleukin-12 (rmIL-12) mediates regression of both subcutaneous and metastatic murine tumors.
Surgical Forum 1993; 44: 518-521.
Nastala, C.L., McKinney, T., Edington H., Tahara, H., Gately, M.K, Storkus, W.J., and M. T.
Lotze. Interleukin-12 (IL-12) induces specific anti-tumor immunity in animals bearing
established subcutaneous murine sarcoma. Surgical Forum 1994; 45.
Hoehnke, C., Nastala, C.L., Tahara, H., Suzuki, T., Edington, H. and M.T. Lotze. The use of
gene transfer of viral IL-10 to facilitate allogeneic skin transplantation. Surgical Forum.
1994; 45.
Nastala, C.L., Edington H., McKinney, T.G., Tahara, H., Brunda, M., Gately, M., Wolf, S.,
Hubbard, B., and M.T. Lotze. Recombinant interleukin-12 (IL-12) administration induces
tumor regression in association with interferon-gamma production. Journal of
Immunology 1994; 153: 1697-706.
Matthes, G, Zabel, D. D., Nastala, C.L., Shestak, K.C. Endometrioma of the abdominal wall
following combined abdominoplasty and hysterectomy: Case report and review of the
literature. Annals of Plastic Surgery 40(6):672-5,1998.
Nastala, C.L., Techniques in Perineal Reconstruction. eMedicine, emedicine.com 2001 (online
journal, peer reviewed)
Nelluri, P.K., Lyons,R.C.., Nastala, C.L., Garza, J.R.. Functional Assessment of the sciatic
nerve after repair with local delivery of FK506 in rats. Canadian Journal of Plastic
Surgery, Vol 10 No x March 2002.
Leong K, Nastala CL, Wang PT. Cosmetic aspects of cranial reconstruction.
Neurosurg Clin N Am. 2002 Oct;13(4):491-503, vi.
Pisano, S.P., Ledoux., Nastala, C.L. Breast Reconstruction in Private Practice. A New Decade
in Breast Reconstruction. Saleh Shenaq., MD.ed Seminars in Plastic Surgery Vol 18 No
2, 2004.
Nastala, C.L., Lyons, R, Kim, B., Massive facial edema following neck dissection and its
treatment with multimodal therapy. submitted.
BOOKS and CHAPTERS
Weinhold, K.J., Lyerly, H.K., Matthews, T.J., Tyler, D.S., Nastala, C.L., and D.P. Bolognesi.
Specific cell-mediated cytotoxicity against HIV-1 envelope glycoprotein coated CD4
cells. in Autoimmune aspects of HIV infection, Andrieu, J.M., Bach, J.F., and P. Even,
eds. Royal Society of Medicine, London 143-151, 1988.
Matthews, T.J., Rusche, J.R., Skinner, M., Putney, S.D., Lyerly, H.K., Nastala, C.L., Tyler,
D.S., Weinhold, K.J., and Bolognesi, D.P. Immunology of the external envelope viral
glycoprotein. in AIDS and associated cancers in Africa, Giraldo, G., Giraldo, E.,
Clumeck, N., Gharbi, M., Kyalwazi, S., and Guy de The, eds. Karger, Basel 237-245,
1988.
Tyler, D.S., Stanley, S.D., Nastala, C.L., Lyerly, H.K., Matthews, T.J., Bolognesi, D.P., and
Weinhold, K.J. Antibody-directed Anti-HIV-1 Cellular Cytotoxicity: Role of NK/K cells
armed with gp120-specific antibodies in therapeutic and vaccine strategies. in Vaccines
89: New Chemical and Genetic Approaches to Vaccination, Prevention of AIDS and
other Viral Bacterial, and Parasitic Diseases, Ginsberg, H., Brown, F., Lerner, R.A., and
R.M. Chanock, eds. Cold Spring Harbor Laboratory, 155-158, 1989.
Lyerly, H.K., Tyler, D.S, Nastala, C.L., and K.J. Weinhold. Anti-HIV-1 ACDD. in AIDS
Vaccine Research and Clinical Trials, Putney, S.D. and Bolognesi, D.P. eds. Marcel
Dekker, Inc. New York 157-177, 1990.
Freeswick, P.D., Nastala, C.L., and T.R.Billiar. Molecular Mechanisms of Hepatic Failure.
R.G. Landes Co. ISBN 1570590982, Dec 1995
Nastala, C.L., McCraw, J.B., and A. McMellin. Vaginal Reconstruction using the Gracilis
Myocutaneous Flap. In Reconstructive and Plastic Surgery of the External Genitalia, Gary
Alter, ed. W.B.Saunders, Co. 1998.
Nastala, C.L., and K.C. Shestak. Breast Reconstruction. In Plastic Surgical Secrets, Weinzweig,
J. ed., Hanley and Belfus, Philadelphia, 254-258, 1999.
Miller, A.R., Chew, H.K., Zellers, R., Nastala, C.L.., and F. Sharkey. Breast Sarcoma. In Cancer
Therapy 2002.
PUBLISHED ABSTRACTS and PRESENTATIONS
Nastala, C.L. Mock circulatory system evaluation of left ventricular assist. Proceedings of the
Annual Conference for Engineering in Medicine and Biology 1984; 37:65.
Kresh, Y., Nastala, C.L., Goldman, S., Fox, D., Brockman, S. The relative buffering power of
cardioplegic solutions. Faculty of the American Society of Engineering in Biology 1985.
Kresh, J.Y., Nastala, C.L, Goldman, S.M., Fox, D., Brockman, S.K. Continuous monitoring of
intramyocardial pH: Relative buffering power of cardioplegic solutions. International
Society for Heart Transplantation 1986.
Nastala, C.L., Tyler, D.S., Lyerly, H.K., Matthews, T.J., Bolognesi, D.P., Weinhold, K.J.
Antibody isotypes directing anti-GP120 antibody dependent cell mediated cytotoxicity.
Proceedings of the Fourth International Conference on AIDS, presented in Stockholm,
Sweden. 1988; 1:2102.
Tyler, D.S., Nastala, C.L., Stine, K.C., Bartlett, J., Bolognesi, D.P., Lyerly, H.K., Weinhold,
K.J. Therapeutic application of interleukin-2 augmentation of HIV-1 specific cellular
immune reactivity. Proceedings of the Fourth International Conference on AIDS,
Stockholm, Sweden. 1988; 2:3524.
Tyler, D.S., Nastala, C.L., Lyerly, H.K., Stanley, D.S., Matthews, T.J., Bolognesi, D.P.,
Weinhold, K.J. HIV specific killer cells armed in situ with cytophilic antibodies.
Proceedings of the Fourth International Conference on AIDS, Stockholm, Sweden. 1988;
1:2183.
Nastala, C.L., Edington, H., McKinney, T, and M. Lotze. Immunologic effects of murine
interleukin-12 in vitro on human and murine lymphoid cells. The Society for Biologic
Therapy of Cancer, presented in Williamsburg, VA. 1992; 37.
Nastala, C.L. and H. Edington. Clostridium septicum associated with benign and malignant
colonic neoplasms and neutropenic enterocolitis. Surgical Infection Society. presented in
Baltimore, MD, 1993.
Nastala, C.L., Edington H., McKinney, T.G., Tahara, H., Brunda, M., Gately, M., Wolf, S.,
Hubbard, B., and M.T. Lotze. Local administration of interleukin-12 blocks in vivo
progression of murine adenocarcinoma and sarcoma. Keystone Symposia,
Immunotherapy of Cancer, presented in Taos, NM. Journal of Cellular Biochemistry,
supplement 17D, 1993; 134.
Tahara, H., Zeh, H., Pappo, I., Nastala, C.L., Robbins, P.D., and M.T. Lotze. Tumor growth
alteration with local interleukin-12 secretion achieved by gene transfer. Keystone
Symposia on Gene therapy, Keystone, CO. 1993.
Nastala, C.L., Edington H., Tahara, H., Zeh, H., McKinney, T., and M. T. Lotze. Murine
interleukin-12 generates anti-tumor reactivity in vitro against murine tumors. Society for
Surgical Oncology, Los Angeles, CA. 1993.
Tahara, H., Zeh, H., Pappo, I., Nastala, C.L., Robbins, P.D., and M.T. Lotze. Suppressed
growth of murine melanoma in vivo with local secretion of interleukin-12 delivered by
transfected fibroblasts. Proceedings of the American Association for Cancer Research,
Orlando FL. 1993; 34:463.
Nastala, C.L., Edington H., Storkus, W.J., and M.T. Lotze. Recombinant Interleukin-12 (rmIL-12) mediates regression of both subcutaneous and metastatic murine tumors. ACS
Surgical Forum San Francisco, CA. 1993; 44: 518-521.
Pappo, I., Tahara, H., Nastala, C.L., Robbins, P.D., Zeh, H., and M.T. Lotze. Cancer gene
therapy with IL-12, alone or in combination with systemic IL-2 administration delays or
prevents the growth of murine sarcomas. Association for Academic Surgery, Hershey,
PA 1993.
Nastala, C.L., McKinney, T., Edington H., Tahara, H., Gately, M.K, Storkus, W.J., and M. T.
Lotze. Interleukin-12 (IL-12) induces specific anti-tumor immunity in animals bearing
established subcutaneous murine sarcoma. ACS Surgical Forum Chicago, IL. 1994; 45.
Nastala, C.L., Newton, E.D., Edington, H.D., and K.C. Shestak. Outcome measures in free flap
reconstruction of the foot. Robert H, IVY Society, Philadelphia, PA 3/97
Kessler, R., Nastala, C.L. Breast Hypertrophy and Protease Inhibitors in the HIV Positive
patient. Texas Society of Plastic Surgeons, Barton’s Creek, TX 10/99
Desvigne, L., Nelluri, P., Nastala, C.L., Garza, J.R.. The Aging neck: Central bands are
independent of platysma decussation. Senior Res Conference, Providence, RI 3/01
Lyons,R., Nelluri, P., Nastala, C.L., Garza, J.R.. A local drug delivery method to enhance nerve
regeneration. Senior Res Conference, Providence, RI 3/01
Nastala, C.L., Pisano, S.M., Ledoux, P.R., Texas Society of Plastic Surgeons, The DIEP Flap in
Breast Reconstruction, The Gold Standard? Hyatt Hill Country, San Antonio TX
9/21/03
Dev, V.R., Ledoux, P.R., Pisano, S.M., Nastala, C.L., American Society of Plastic Surgeons,
Innervating the DIEP Flap: Anatomical Considerations to Simplify and Improve
Somatosensory function of the Reconstructed Breast. San Diego California, 10/26/03
Nastala, C.L., Pisano, S.M., Ledoux, P.R., American Society of Reconstructive Microsurgery
Surgeons, The DIEP Flap in Breast Reconstruction, Improving the Efficiency of Health
Care Delivery . Palm Springs, CA, 1/2004
Pisano, S.M., Ledoux, P.R., Nastala, C.L., American Society of Reconstructive Microsurgery
Surgeons, Clinical Course Performing the DIEP Flap Breast Reconstruction in Private
Practice Tucson AZ, 1/2006
INVITED TALKS AND LECTURES
Treatment of Secondary Deformities in Cleft lip and Palate. Plastic Surgery Grand Rounds,
University of Texas Health Science Center at San Antonio 10/1/98
Current Progress in Melanoma. The San Antonio Surgical Society 10/15/98
Methods of perineal reconstruction. Plastic Surgery Grand Rounds, University of Texas Health
Science Center at San Antonio 1/14/99
The use of the Posterior Thigh Flap in Vaginal Reconstruction. Society of Air Force Clinical
Surgeons. San Antonio, TX 3/31/99
Management of tendon injuries. Plastic Surgery Grand Rounds, University of Texas Health
Science Center at San Antonio 9/16/99
Breast Hypertrophy and Protease Inhibitors in the HIV Positive patient: The role of the Plastic
Surgeon. Texas Society of Plastic Surgeons, Barton’s Creek, TX 10/8/99
Advances in Wound Care. San Antonio International Society of Plastic Surgeons, San Antonio,
TX 4/2000
Moderator TexMed 2000; Plastic Surgery Session of the Texas Medical Association, San
Antonio, TX 5/25/2000
Skin Sparing Mastectomy and Immediate Breast Reconstruction, State of the Art, TexMed 2000;
Texas Medical Association, San Antonio, TX 5/25/2000
Decubitus Ulcers, When in Surgery Appropriate? Texas Medical Association, TexMed 2000;
San Antonio, TX 5/25/2000
Texas Society of Plastic Surgeons, Short Scar Breast Surgery: Is it here to stay? La Cantera, San
Antonio TX 9/21/01
Advanced Concepts in Cosmetic and Reconstructive Breast Surgery. Plastic Surgery Grand
Rounds, University of Texas Health Science Center at San Antonio 2/14/02
CURRENT PROJECTS (SUBMITTED OR IN PROGRESS)
Nastala, C.L., Current recommendations and clinical algorithms for prophylactic mastectomy
Nastala, C.L., Perceptions and attitudes regarding breast reconstruction in the Hispanic
community.
Nastala, C.L., Outcome measures in flap reconstruction of pressure sores
Nastala, C.L., Cost-effectiveness and clinical benefits of VAC therapy in complex wounds care
TEACHING SERVICE AT UTHSCSA
Medical Student Anatomy Lectures: Clinical Correlations Human Anatomy Dissection Course
Lectures on Hand Anatomy, Trunk Anatomy, The Anatomy of Flaps and Grafts.
Clinical Anatomical Correlations in Cleft Lip and Palate Repair
Medical Student Clinical Lectures in Plastic and Reconstructive Surgery
Responsible for weekly lectures for medical students including an introduction to Plastic
Surgery, Hand surgery, Breast reconstruction, Burn Management, Wound care, and
Facial trauma management.
Graduate Resident Clinical Education Core Curriculum Course
Responsible for planning and implementing weekly Plastic Surgery Conference
designed to comprehensively review of the entire spectrum of Plastic and Reconstructive
Surgery. Weekly lectures have specific goals and objectives for each topic to help
residents organize their own leaning and provide an in depth understanding of current
practice of Plastic Surgery. Scholarship and an environment of inquiry is fostered. I
attend clinical teaching workshops and instructor courses regularly to consistently
improve teaching ability.
Weekly Clinical Teaching: Plastic Surgery Attending Rounds
Coordinator. Weekly City Wide Plastic Surgery Grand Rounds.
Responsible for coordinating Grand Rounds involving entire spectrum of Plastic and
Reconstructive Surgery clinical practice and basic science. Ensures presentations meet
continuing medical education (CME) guidelines and objectives. Encourage participation
of all clinical and full time academic faculty
Completed UTHSCSA “Effective Clinical Teaching” instructor’s course February 24-25, 2000,
13 contact hours CME. Division of Educational Research and Development, Office of
Educational Resources. William D. Hendrickson, MA, MS Workshop Director
Completed UTHSCSA Clinical Teaching Spring Workshop, March 29 through May 3, 2000.
Division of Educational Research and Development, Office of Educational Resources.
Nancy C. Hudepohl, PhD Course Director
Mentor: Medical Student Billy Kim, MS2 Summer internship program: Plastic Surgery Clinical
Research in wound healing, UTHSCSA
Mentor: Robert Kessler, M.D., Senior Resident in Plastic Surgery at the University of Texas
Helath Science Center at San Antonio: Best Paper Award at the 2000 Senior Plastic
Surgery Resident’s Conference, U Florida, Gainsville. “HIV-1 Protease inhibitors and the
Plastic Surgeon”
OTHER
Nastala, C.L. Molecular species of rabbit skeletal tropomyosin: Correlation of effects on
actomyosin adenosine triphosphatase with conformational stability. Thesis in the
Department of Biochemistry and Molecular Biology, Harvard University, 1985.
GRANTS and PROTOCOLS
IL-12 gene therapy using direct injection of tumors with genetically engineered autologous
fibroblasts. Hideaki Tahara, M.D., PhD; co investigator 1994
Phase 1 dose escalating study of recombinant human interleukin-12 (rhIL-12) administered ny
intravenous injection in patients with advanced solid malignancies. Michael T. Lotze,
M.D. co-investigator 1995
Cost-effectiveness and clinical benefits of VAC therapy in the treatment of Veterans requiring
skin grafting of wounds. Chet L Nastala, M.D., Pramrod Nelluri, M.D., Robert C. Lyons,
M.D. 2000. ($40,000, funding pending)
Reconstruction of Nipple/Areola with tattooing in Breast Cancer Patients.. San Antonio Area
Foundation $3,415. 2001