MCB 135K: Physiology of the Aging Process Spring 2008 MWF 12-1, 120 Latimer Professor: Teaching Assistant: Paola S. Timiras (timiras@berkeley.edu) Sundari Chetty (schetty@berkeley.edu) Lect. 1 Date January 23 Lecture Title Chap.* “The Journey of Life: Development, Adulthood, Aging” 1 Lecturer PS Timiras 2 January 25 Demography of Aging 2 J Wilmoth 3 January 28 Theories of Aging 5 PS Timiras 4 January 30 Delaying (or accelerating) the degenerative diseases of aging 5, 6 B Ames 5 February 1 Comparative Aging 3 PS Timiras 6 February 4 Functional Assessment of the Elderly I 3 PS Timiras 7 February 6 Functional Assessment of the Elderly II 3 PS Timiras 8 February 8 Diseases of Aging I 3 PS Timiras 9 February 11 Cellular Senescence 4 J Campisi 10 February 13 Telomeres 4 J Campisi 11 February 15 Replicative Aging in Budding Yeast 4 M McMurray February 18 President’s Day Holiday 12 February 20 Epidemiology of Aging 3 W Satariano 13 February 22 Diseases of Aging II 3 PS Timiras February 25 MIDTERM 1 14 February 27 Aging of the Nervous System, Structural Changes 6 S Chetty 15 February 29 Brain Imaging and Memory 7 M. D’Esposito 16 March 3 Apoptosis 4 J Campisi 17 March 5 Aging of the Visual System 8 G Haegerstrom-Portnoy 18 March 7 Aging of the Nervous System, Functional Changes 7, 8 PS Timiras 19 March 10 Aging of the Cardiovascular System 15, 16 PS Timiras 20 March 12 Atherosclerosis 15, 16 PS Timiras 21 March 14 Aging of the Cardiovascular System – Lipoproteins 16 T Forte 22 March 17 Promoting Health and Longevity Interventions: Exercise 24 Bioenergetics (To Be Announced) 23 March 19 Aging of Skeletal Muscle 20 F Navazio March 21 Aging of Cardiac Muscle and Cardiac Failure 20 F Navazio March 24-28 Spring Recess 24 March 31 Aging of the Skeleton (To Be Announced) 20 25 April 2 Effects of Aging on Mobility and Independence 20 A Poggio 26 April 4 MIDTERM 2 27 April 7 The Hypothalamo-Pituitary-Adrenal System 9 PS Timiras 28 April 9 Stress, Adaptation, Longevity 9 PS Timiras 29 April 11 The Hypothalamo-Pituitary-Thyroid System 12 PS Timiras 30 April 14 The Female Reproductive System 10 PS Timiras 31 April 16 Hormone Replacement Therapy 32 April 18 Carbohydrate Metabolism, Diabetes, and Aging 13 PS Timiras 33 April 21 Male Reproductive System 11 PS Timiras 34 April 23 Immune System I 14 H Sternberg 35 April 25 Immune System II 14 H Sternberg 36 April 28 Aging of the Urinary Tract and the Prostate 18 PS Timiras 37 April 30 The Lung – An Environmentally Embattled Organ 17 PS Timiras 38 May 2 Aging of the Gastrointestinal Tract 19 PS Timiras 39 May 5 Aging of the Skin 21 J Napoli 40 May 7 Nutrition and Aging 23 F Navazio 41 May 9 Towards Independent Living of the Elderly: Information 25 R Bajcsy 22 PS Timiras 9, 10, 11, 12, 13 PS Timiras and Communication Technology 42 May 12 Pharmacology and Drug Management in the Elderly MAY 19 FINAL EXAM 12:30 – 3:30 * FROM THE TEXT (Optional):Physiological Basis of Aging and Geriatrics, 4rd Ed. Informa Healthcare, NY, 2007 TESTS AND GRADING There will be two midterms and one final examination. There will be no make-up examination. If you miss one midterm test because of illness, you must present a written, verifiable medical excuse and your grade for the course will be calculated on a pro-rated score. The letter grade at the end of the Spring semester will be determined from numerical grades distributed as follows: Midterms (2 x 100) 200 points Final (5/15, 12:30-3:30) 200 points Final Exam Group 11: MONDAY, MAY 19, 2008 1230-330P Room: TBA Attention: Website for MCB 135K: http://mcb.berkeley.edu/courses/mcb135k/