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Clinical Epigenetics

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Featured review: Imprinting disorders

Imprinting disorders are a group of congenital diseases characterised by overlapping clinical features affecting growth, development and metabolism, and common molecular disturbances, affecting genomically imprinted chromosomal regions and genes.

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1.

Research

Reciprocal changes in DNA methylation and hydroxymethylation and a broad repressive epigenetic switch characterize FMR1 transcriptional silencing in fragile X syndrome

Sarah Brasa, Arne Mueller, Sébastien Jacquemont, Florian Hahne, Izabela Rozenberg,

Thomas Peters, Yunsheng He, Christine McCormack, Fabrizio Gasparini, Salah-Dine

Chibout, Olivier Grenet, Jonathan Moggs, Baltazar Gomez-Mancilla and Rémi Terranova

Published on: 5 February 2016

2.

Research

H3K4 tri-methylation breadth at transcription start sites impacts the transcriptome of systemic lupus erythematosus

Zhe Zhang, Lihua Shi, Noor Dawany, Judith Kelsen, Michelle A. Petri and Kathleen E.

Sullivan

Published on: 2 February 2016

3.

Research

The cardiovascular and hypothalamus-pituitary-adrenal axis response to stress is controlled by glucocorticoid receptor sequence variants and promoter methylation

Ting Li-Tempel, Mauro F. Larra, Estelle Sandt, Sophie B. Mériaux, Andrea B. Schote,

Hartmut Schächinger, Claude P. Muller and Jonathan D. Turner

Published on: 28 January 2016

4.

Research

Epigenetic associations of type 2 diabetes and BMI in an Arab population

Wadha A. Al Muftah, Mashael Al-Shafai, Shaza B. Zaghlool, Alessia Visconti, Pei-

Chien Tsai, Pankaj Kumar, Tim Spector, Jordana Bell, Mario Falchi and Karsten Suhre

Published on: 28 January 2016

5.

Research

Insulin-like growth factor axis in pregnancies affected by fetal growth disorders

Aamod R. Nawathe, Mark Christian, Sung Hye Kim, Mark Johnson, Makrina D.

Savvidou and Vasso Terzidou

Published on: 27 January 2016

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Most accessed articles

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1.

Research

Methylation analysis and diagnostics of Beckwith-Wiedemann syndrome in 1,000 subjects

Abdulla Ibrahim, Gail Kirby, Carol Hardy, Renuka P Dias, Louise Tee, Derek Lim,

Jonathan Berg, Fiona MacDonald, Peter Nightingale and Eamonn R Maher

Published on: 4 June 2014

2.

Review

Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors

Geneviève P Delcuve, Dilshad H Khan and James R Davie

Published on: 12 March 2012

3.

Review

Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells

Praveen Rajendran, Emily Ho, David E Williams and Roderick H Dashwood

Published on: 26 October 2011

4.

Research

DNA hydroxymethylation age of human blood determined by capillary hydrophilic-interaction liquid chromatography/mass spectrometry

Jun Xiong, Han-Peng Jiang, Chun-Yan Peng, Qian-Yun Deng, Meng-Dan Lan, Huan

Zeng, Fang Zheng, Yu-Qi Feng and Bi-Feng Yuan

Published on: 23 July 2015

5.

Review

A macroepigenetic approach to identify factors responsible for the autism epidemic in the United States

Renee Dufault, Walter J Lukiw, Raquel Crider, Roseanne Schnoll, David Wallinga and

Richard Deth

Published on: 10 April 2012

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Archival Content

In October 2011, Clinical Epigenetics became a fully open access journal and is now published as part of BioMed Central's portfolio of journals. To view the journal's content prior to this transition, please see SpringerLink .

Review series

Breakthroughs in clinical epigenetics

Edited by: Dr Marianne Rots

First published: 1 March 2015

Aims & Scope

Clinical Epigenetics is an open access, peer-reviewed journal that encompasses all aspects of epigenetic principles and mechanisms in relation to human disease, diagnosis and therapy.

Clinical trials and research in disease model organisms are particularly welcome. The journal is divided into the following sections:

 Aging, development, imprinting and reproductive epigenetics

 Allergy, immunology, pathogens and inflammation

Cancer epigenetics and diagnostics

 Cardiovascular epigenetics

Endocrinology and metabolic disease

Epigenetic therapy and clinical trials

 Innovative epigenetics therapies

Neurology and psychiatry

 Nutritional and environmental epigenetics

 All other subjects

For more information on the the section aims and scope visit our sections information page .

Accepting submissions: Asthma genetics and epigenetics

Clinical Epigenetics and Asthma, Allergy and Clinical Immunology are calling for submissions to a cross-journal thematic series Guest Edited by Dr Kari Nadeau (Stanford University) and

Professor Rachel Miller (Columbia Medical University).

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Society Information

The "Clinical Epigenetics Society" (CLEPSO) is a non-profit organization founded at Saarland

University.

The society has five main objectives:

 Promotion and support of scientific research projects and initiatives within the field of clinical epigenetics.

 Promotion of the scientific exchange amongst its members.

 Encouragement and support of relations to national and international societies within the

 area of clinical and translational research.

Development of an international research and scientific network within the field of clinical epigenetics.

Providing a forum for encouraging discussions and contributions to the advancement of clinical epigenetics, through the Clinical Epigenetics journal, Blogs, scientific symposia, meetings, and newsletters.

Upcoming society meeting

6th Clinical Epigenetics International Meeting

March 3rd - 4th, 2016 - Düsseldorf, Germany

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From the blog

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3D chromatin organization changes: a brief overview

Published on: 28 January 2016

Do stress factors alter DNA methylation during aging?

Published on: 17 December 2015

The Epigenetics and Chromatin Clinic

Published on: 09 November 2015

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