PMV file 4 to reviewers (logistic OR and Cox HR lists)
Comparison between logistic regression results for survival and Cox regression results for mortality
Predictor
Diagnoses at PMV onset (excluding respiratory failure)
Septicemia
Other infectious and parasitic diseases
Neoplasms
Diabetes mellitus
Nutritional deficiencies
Fluid and electrolyte disorders
Other endocrine/nutritional/metabolic diseases & immunity disorders
Coagulation and hemorrhagic disorders
Other diseases of the blood and blood-forming organs
Mental illness
Diseases of the nervous system and sense organs
Hypertension
Heart valve disorders
Acute myocardial infarction and coronary atherosclerosis
Cardiac dysrhythmias
Other diseases of the heart
Cerebrovascular diseases
Other diseases of the circulatory system
Pneumonia
Chronic obstructive pulmonary disease and bronchiectasis
Asthma
Other diseases of the respiratory system
Gastrointestinal hemorrhage
Other diseases of the digestive system
Acute and unspecified renal failure
3-month survival
Logistic regression (survival)
6-month survival 1-year survival
2-year survival
adjusted OR†
adjusted OR†
adjusted OR†
0.52 **
0.79 **
0.30 **
0.78 **
0.74 *
0.99
0.83 **
0.40 **
1.02
1.27 *
1.07
1.32 **
0.92
0.88
0.89
0.70 **
1.06
0.60 **
0.81 **
1.14 **
0.88
0.83 **
0.72 **
0.84 **
0.39 **
-1-
0.56 **
0.81 **
0.31 **
0.77 **
0.88
0.94
0.83 *
0.55 **
1.09
1.26 *
1.06
1.30 **
1.02
0.98
0.87
0.73 **
1.03
0.73 **
0.84 **
1.16 **
0.85
0.87 **
0.74 **
0.90 *
0.40 **
adjusted OR†
0.60 **
0.80 **
0.30 **
0.72 **
0.84
0.97
0.79 **
0.61 *
0.98
1.20
1.04
1.41 **
1.18
1.10
0.91
0.76 *
1.00
0.80 *
0.86 **
1.10
0.95
0.89 *
0.76 **
0.99
0.48 **
0.63 **
0.82 **
0.31 **
0.73 **
0.71 *
0.96
0.72 **
0.74
0.95
1.19
1.07
1.39 **
1.17
1.23 **
0.97
0.82
0.99
0.94
0.88 **
1.10
1.00
0.92
0.79 *
0.99
0.56 **
Cox
Regression
(mortality)
adjusted HR†
1.33 **
1.08 **
1.70 **
1.16 **
1.18 **
1.04
1.13 **
1.39 **
1.01
0.93
0.97
0.86 **
0.97
0.98
1.06
1.19 **
1.02
1.16 **
1.10 **
0.97
1.10 *
1.08 **
1.13 **
1.04
1.49 **
PMV file 4 to reviewers (logistic OR and Cox HR lists)
Predictor
3-month survival
Logistic regression (survival)
6-month survival 1-year survival
2-year survival
adjusted OR†
adjusted OR†
adjusted OR†
**
adjusted OR†
**
1.12
**
*
adjusted HR†
0.94 **
1.13 **
1.09
1.09 *
0.95
0.91
0.68 **
0.85 **
0.87 **
1.07
1.41 **
0.84 *
1.14 **
1.10
1.19 **
Urinary tract infections
Other diseases of the genitourinary system
Complications: pregnancy/childbirth/puerperium
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Congenital anomalies
Spinal cord injury
Intracranial injury
Other injury and poisoning
Symptoms; signs; and ill-defined conditions and factors
Shock
Parkinson's disease
Heart failure
Alcoholic liver disease
Non-alcoholic liver disease
1.25
0.78 **
0.80
0.82 **
0.93
0.99
2.00 **
1.16
0.99
0.89
0.42 **
1.80 **
0.77 **
1.18
0.60 **
1.19
0.79
0.70
0.75 **
1.06
1.11
1.90 **
1.32 **
1.04
0.87
0.47 **
1.94 **
0.76 **
0.83
0.67 **
0.75
0.66
0.75 **
1.13
1.26
1.72 **
1.30 **
1.14 *
0.82
0.55 **
1.82 **
0.79 **
0.83
0.72 **
0.78 **
0.54
0.77 **
1.17
1.30
1.74 **
1.34 **
1.30 **
0.91
0.63 **
1.32
0.77 **
0.81
0.84
Multiple sclerosis/Other hereditary & degenerative nervous system
conditions
0.98
1.10
1.11
1.12
0.95
0.44 **
0.43 **
0.41 **
0.43 **
1.50 **
1.14 **
0.93 **
0.91 **
0.98
0.99
0.96
1.03
1.07
1.12 **
0.95
0.89 **
0.94 **
0.92
0.96
1.00
0.91
1.08
0.96
0.88 **
0.93 **
0.85
1.06
1.02
1.00
1.05
0.94
0.89 **
0.91 **
0.80 *
1.05
1.08
0.86
0.94 **
1.03 *
1.05 **
1.02 *
1.04
0.98
0.99
0.98
Chronic renal failure
Disease history (Number of admissions for the disease in the previous year)
Septicemia
Other infectious and parasitic diseases
Neoplasms
Diabetes mellitus
Nutritional deficiencies
Fluid and electrolyte disorders
Other endocrine/nutritional/metabolic diseases & immunity disorders
Coagulation and hemorrhagic disorders
-2-
**
1.14
**
Cox
Regression
(mortality)
PMV file 4 to reviewers (logistic OR and Cox HR lists)
Predictor
Other diseases of the blood and blood-forming organs
Mental illness
Diseases of the nervous system and sense organs
Hypertension
Heart valve disorders
Acute myocardial infarction and coronary atherosclerosis
Cardiac dysrhythmias
Other diseases of the heart
Cerebrovascular diseases
Other diseases of the circulatory system
Pneumonia
Chronic obstructive pulmonary disease and bronchiectasis
Asthma
Other diseases of the respiratory system
Gastrointestinal hemorrhage
Other diseases of the digestive system
Acute and unspecified renal failure
Urinary tract infections
Other diseases of the genitourinary system
Complications: pregnancy/childbirth/puerperium
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Congenital anomalies
Spinal cord injury
Intracranial injury
Other injury and poisoning
Symptoms; signs; and ill-defined conditions and factors
3-month survival
Logistic regression (survival)
6-month survival 1-year survival
2-year survival
adjusted OR†
adjusted OR†
adjusted OR†
**
0.85
0.99
1.03
1.00
0.99
1.00
1.05
1.14 **
1.11 **
1.04
1.14 **
1.00
1.04
1.03
1.04
1.00
1.24 **
0.96
0.96
0.82
0.94 *
0.97
0.85
1.31
1.15 *
0.93 *
0.96
-3-
adjusted OR†
**
0.83
1.00
1.03
1.01
0.96
0.98
1.04
1.09
1.09 **
0.99
1.11 **
1.02
1.04
0.99
0.99
0.99
1.15 *
0.97
0.95
0.92
0.92 **
0.94
0.96
1.08
1.14 *
0.96
0.98
**
0.78
1.00
1.05
1.00
0.94
0.96
1.04
1.03
1.08 **
0.99
1.08 **
1.01
1.07
1.00
0.99
0.98
0.97
0.94 *
0.96
0.84
0.92 *
0.92 *
1.00
0.97
1.08
0.98
0.96
**
0.80
0.99
0.99
0.96
1.00
0.95
0.99
1.02
1.06 *
0.98
1.04
1.00
1.01
1.03
1.00
1.00
0.98
0.97
0.95
1.06
0.94
0.92
1.05
1.04
1.03
0.98
0.98
Cox
Regression
(mortality)
adjusted HR†
1.08 **
0.99
1.00
1.00
1.03
1.01
1.00
0.96
0.97 **
1.00
0.97 **
0.99
0.98
0.99
0.99
1.01
0.92 **
1.02
1.01
0.95
1.04 *
1.01
1.03
0.92
0.97
1.03 *
1.01
PMV file 4 to reviewers (logistic OR and Cox HR lists)
Predictor
Shock
Parkinson's disease
Heart failure
Alcoholic liver disease
Non-alcoholic liver disease
Multiple sclerosis/Other hereditary & degenerative nervous system
conditions
Chronic renal failure
3-month survival
Logistic regression (survival)
6-month survival 1-year survival
2-year survival
adjusted OR†
adjusted OR†
adjusted OR†
**
adjusted OR†
**
*
Cox
Regression
(mortality)
adjusted HR†
0.88 **
1.03
1.03
1.18 **
1.06 **
1.32
0.98
0.94 *
0.94
0.86 **
1.25
0.95
0.95
0.92
0.86 **
1.18
0.99
0.91 *
0.86
0.89 *
1.12
1.01
0.91 *
0.72 *
0.92
1.11
1.08
1.02
0.97
1.01
0.91 **
0.88 **
0.83 **
0.78 **
1.06 **
0.89 **
0.84 **
0.79 **
0.78 **
1.10 **
35–44
0.67 **
0.64 **
0.61 **
0.65 **
1.48 **
45–54
0.67 **
0.60 **
0.54 **
0.55 **
1.66 **
55–64
0.62 **
0.52 **
0.43 **
0.39 **
2.00 **
65–74
0.44 **
0.36 **
0.28 **
0.25 **
2.54 **
75–84
0.36 **
0.27 **
0.19 **
0.16 **
2.96 **
≥85
0.29 **
0.21 **
0.15 **
0.11 **
3.31 **
1.06 **
1.06 **
1.07 **
1.06 **
0.98 **
0.89 *
0.94
0.99
0.99
1.04
Gender (ref: female)
Male
Age group (ref: 17–34)
PMV incidence year
continuous variable in the value range: [1998, 2002]
Branch of hospital location (ref: Taipei)
Northern region
Central region
1.13
**
1.14
**
1.12
*
*
Southern region
1.04
0.97
0.87
Kao-Ping region
0.89 *
0.88 *
0.84 **
-4-
1.13
*
0.96
0.86
*
1.03
0.82 **
1.08 **
PMV file 4 to reviewers (logistic OR and Cox HR lists)
Cox
Regression
(mortality)
3-month survival
Logistic regression (survival)
6-month survival 1-year survival
2-year survival
adjusted OR†
adjusted OR†
adjusted OR†
adjusted OR†
0.92
1.00
0.87
0.90
1.03
Regional hospital
0.92 *
0.89 **
0.85 **
0.87 **
1.05 *
Local hospital
0.90 *
0.86 **
0.87 **
0.85 **
1.08 **
Small city or town
1.02
1.04
1.02
1.04
0.99
Remote or rural area
0.95
0.98
1.02
1.04
1.00
The middle 1/3 of the population
0.85 **
0.85 **
0.89 **
0.88 **
1.05 *
The top 1/3 of the population
1.08
1.12 *
1.08
1.07
0.96
Predictor
Eastern region
adjusted HR†
Hospital type (ref: medical centre)
NHI registration location (ref: big city)
Salary class in NHI registration (ref: bottom 1/3 class)
Number of patients
Model significance (results from log-likelihood ratio tests)
19,127
19,127
19,127
19,127
19,127
χ2(103)=
3,099.81**
χ2(103)=
3,032.36**
χ2(103)=
2,939.46**
χ2(103)=
2,652.06**
χ2(103)=
3,518.8**
PMV: prolonged mechanical ventilation
OR: odds-ratio.
CI: confidence interval.
HR: hazard ratio.
*
p<0.05; ** p<0.01.
†
The OR and the HR are adjusted for all other covariates.
-5-