Group B Streptococcus - What Does the Research
Really Say?
In the US, most pregnant women have heard of Group B Streptococcus, but unfortunately know little
information about the condition and the real risks involved. The American College of Obstetricians and
Gynecologists (ACOG) and the US Centers for Disease Control and Prevention (CDC) recommend that all
pregnant women be screened between weeks 35 and 37 of their pregnancies to determine if they are carriers of
GBS by taking a swab of the vaginal and rectal areas. About 30% of pregnant women are found to be colonized
with GBS in one of both areas.
The recommended treatment by the CDC and ACOG is intravenous antibiotics during birthing because GBS
can be passed from you to the baby during delivery and cause sepsis (a blood infection), pneumonia, and/or
meningitis (an infection of the fluid and lining of the brain).
WHY WOULDN'T A MOTHER CHOOSE ANTIBIOTICS?
To answer this question, we need to look at what GBS is and why it might not be such a good idea to
recommend that a third of all pregnant women expose themselves and their babies to antibiotics from birth.
GBS is a bacterium that normally lives in the intestinal tracts of many healthy people. In truth, you should
never be termed “GBS infected” but rather “GBS colonized”. Remember that the intestinal tract is composed of
normal healthy bacteria, including GBS. It is usually a transient condition that will come and go through your
pregnancy. You may swab positive at 36 weeks, only to be negative again at 38 weeks.
GBS can cause problems only when it is present in the genital area during birthing and delivery. When this
happens, there is a very small risk that the bacteria will be passed on to the baby and become sick.
Approximately 0.0225% of women found to be GBS+ at 35 to 37 weeks who aren’t treated with antibiotics will
have a baby who becomes ill. That's 1 in 4444 babies who will become ill.
But here’s the most important point: in women who do receive antibiotics, 0.0225% of babies will go on to
become ill from GBS. That's also 1 in 4444 babies who will become ill.
In truth, there are many reasons you don’t want antibiotics for Group B Streptococcus. These include:
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Increasing occurrence of antibiotic-resistant infections (“superbugs” - think MRSA)
Use of antibiotics has increased risk of developing other infections (sepsis & E. Coli included)
Colonization of GBS is a poor indicator of which babies will become ill
Antibiotics fail to prevent infection in 30% of cases
The most-commonly used antibiotic for treating Group B Streptococcus during birthing is penicillin. Fewer
bacteria currently show a resistance to penicillin than to other antibiotics used to treat GBS. Ampicillin and
amoxicillin are virtually worthless for treating GBS due to overuse that has now made Group B Streptococcus
resistant to them. It’s only a matter of time until penicillin is also ineffective against GBS. The superbug is on
its way.
If you are allergic to penicillin, your options decrease. 29% of Group B Streptococcus strains are resistant to
non-penicillin antibiotics. If you don’t know if you’re allergic or even if you’ve had it in the past, there’s a 1/10
chance of a mild reaction such as a rash, and a 1/10,000 chance of anaphylaxis, a life-threatening allergic
reaction.
Two in 10,000 babies may be saved by antibiotics during birth, but this comes at the cost of giving 1/3 of all
pregnant women antibiotics. The risks of developing a superbug are greater than the chances of saving your
baby with antibiotics. This also doesn’t take into account how many other infections babies given antibiotics
may develop other than Group B Streptococcus.
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WHAT ARE THE RISK FACTORS FOR MOTHERS WITH GBS?
There are three significant factors that place your baby at increased risk of infection: fever during birthing, water
breaking 18 hours or more before birthing (prolonged rupture of membranes, or PROM), and/or birthing or
broken water before 37 weeks. Other factors that can contribute to a newborn's risk of contracting Group B
Streptococcus infection include age, ethnicity, and medical criteria, such as the following: being born to a
mother who is less than 20 years old, being African American, large amounts of GBS bacteria in the vaginal
tract, and having a previous baby with GBS disease.
WHAT ARE THE SYMPTOMS OF GBS INFECTION IN A BABY?
There are two forms of Group B Streptococcus infection: early and late onset. In early-onset GBS disease, your
baby will become ill within seven days of birth. In severe early-onset GBS infection, about 6 percent of babies
will die from complications of the infection. Full-term babies are less likely to die; 2-8% suffer fatal
complications. Premature babies have mortality rates of 25-30%. Late-onset GBS infection is more complicated
and may not have anything to do with whether you had GBS during birthing. It occurs between seven days and
three months of age.
Symptoms of early-onset Group B Streptococcus infection include any of the following: fever or abnormally low
body temperature, jaundice (yellowing of the skin and whites of the eyes), poor feeding, vomiting, seizures,
difficulty in breathing, swelling of the abdomen, and bloody stools. The most common symptom is difficulty
breathing, which is also the most common complication in babies whose mothers choose drugs during birthing.
Since these symptoms can occur in so many circumstances not related to GBS, a C-Reactive protein test can be
given to a symptomatic baby to reveal the presence of an active infection.
ARE THERE ALTERNATIVES TO ANTIBIOTICS?
Even though Group B Streptococcus is a transient infection, without an active effort to eradicate the GBS
colonization, it is likely that you will still be colonized after 37 weeks. We will see better outcomes by simply
focusing on reducing colonization rather than treating it after the fact.
There are many probiotic, natural remedies that focus on restoring a healthy vaginal flora balance, reducing
bacterial overgrowth, and directly reducing the bacterial concentration. These treatments can begin at 32 weeks
rather than waiting for a positive culture. Another option is to NOT screen for beta strep during pregnancy, but
to follow a strict protocol during birthing if you have the following risk factors: 1) fever over 38 degrees Celsius,
2) pre-term birthing < 37 weeks, 3) prolonged rupture of membranes > 18 hours, 4) multiple births, and 5)
previously-infected baby. In these cases antibiotics may be indicated. Those infants who are symptomatic
(fever, fast breathing, poor feeding, high pitched cry) can be evaluated for sepsis and given antibiotics for 48-72
hours. Alternately, you can request a C-reactive protein test to determine the presence of an active infection
before giving antibiotics to the baby.
TREATMENT OPTIONS
Below are a series of alternative treatment options for you to consider:
TREATMENT OPTION #1:
If you have a heavy colonization, use EHB capsules by NF Formulas given over a 10-day period (6 caps per
day), and Tea tree oil vaginal suppositories 3-4 times daily for that time. This can be done on a small size
tampon or a cotton ball, whichever is more comfortable. Colonization is measured on a range from 1-4 with 1
being minimal and 4 being heavy colonization.
TREATMENT OPTION #2:
Take 500mg of Vitamin C every 4 waking hours, 1 EHB (NF Formulas) capsule every 4 waking hours, Propolis
4x daily, and insert a tampon soaked in 2% Tea Tree oil solution (2%Tea Tree essential oil, 98% Olive oil).
Leave the tampon in for 4 hours each day for 6 days.
TREATMENT OPTION #3:
Take 3 caps of Congaplex by Standard Brands 3 times a day for a week, then re-culture. If still positive, take 1
cap per day until the end of pregnancy.
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TREATMENT OPTION #4:
At 32 weeks, begin to take a supplement of 500 mg of Vitamin C and one cup of burdock root and Echinacea
root infusion. To prepare the infusion, steep one-half ounce of each of the herbs in four cups of boiling water for
two hours. Strain and take the above dose, storing the rest in the refrigerator for the next day.
TREATMENT OPTION #5
Drink 3 teaspoons of Colloidal Silver, which is silver suspended in water, per day between meals. Hold the
liquid in your mouth a few minutes before swallowing. Colloidal Silver can be purchased in most health food
stores. It is antibiotic in nature and safe in pregnancy.
TREATMENT OPTION #6:
Use of oral antibiotics: 3 a day starting at week 37 and then one a day until birthing begins. When birthing
begins, take one every 4-6 hours until the baby is born. (It seems like a lot, but it lets you avoid the cascade of
interventions that IV antibiotics brings at the hospital).
TREATMENT OPTION #7:
Treat with antibiotics by intramuscular injection (IM) before the birth. This method will cover you for 30 days
after the injections (4 injections total to give the full dose).
TREATMENT OPTION #8:
Take 1/3 teaspoon of echinacea and astragalus tinctures twice daily. You can get dried astragalus in the herb
department of health food stores. Cook two strips into a pot of rice or soup 2-3 times per week Remove the
strips when done cooking and eat the rice or soup. Astragalus is an immune system tonic used in Chinese
medicine.
TREATMENT OPTION #9:
Make a garlic elixir by blending 1/2 cup of honey, 1/4 cup of apple cider vinegar, and half a bulb of fresh garlic
until liquified. Take 1/2 teaspoon up to twice daily. Season to taste with honey or vinegar.
PREVENTION TIPS
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Breastfeed immediately and frequently. Colostrum is the best antibiotic treatment your baby could ever get.
Refuse vaginal exams
DO NOT permit artificial rupture of membranes.
REFERENCES
F. Smaill, "Intrapartum Antibiotics for Group B Streptococcal Colonization," Cochrane Database Syst Rev 2 (2000):
CD000115: www.ncbi.nlm. nih.govl.
S. D. Manning et al., "Correlates of Antibiotic-Resistant Group B Streptococcus Isolated from Pregnant Women," Obstetric
Gynecology 101, no. 1 (2003): 74-79
R. K. Edwards et al., "Intrapartum Antibiotic Prophylaxis 2: Positive Predictive Value Antenatal Group B Streptococci
Cultures and Antibiotic Susceptibility of Clinical Isolates," Obstetric Gynecology 100, no. 3 (2002): 540-544.
M. Dabrowska-Szponar and J. Galinski. "Drug Resistance of Group 9 Streptococci," Pol Merkuriusz Lek 10, no. 60(2001):
442-444.
M. L. Bland et al., "Antibiotic Resistance Patterns of Group B Streptococci in Late Third Trimester Rectovaginal Cultures,"
American Journal of Obstetric Gynecology 184. no, 6 (2001): 1125-1126.
T. B. Hyde ct al., "Trends in Incidence and Antimicrobial Resistance of Early-Onset Sepsis: Population-Based Surveillance
in San Francisco and Atlanta," Pediatrics 110, no. 4 (2002): 690-695.
R. S. McDuffie Jr. et al., "Adverse Perinatal Outcome and Resistant Enterobacteriaceae after Antibiotic Usage for Premature
Rupture of Membranes and Group B Streptococcus Carriage," Obstetric Gynecology 82, no. 4, pt. 1 (1993): 487-489.
C. V. Towers and G. G. Briggs, "Antepartum Use of Antibiotics and Early-Onset Neonatal Sepsis: The Next Four Years,"
American Journal of Obstetric Gynecology 187, no. 2 (2002): 495-500.
S. J. Schrag et al., "A Popular/on Based Comparison of Strategies Co Prevent Early-Onset Group B Streptococcal Disease in
Neonates," New England Journal of Medicine 347 (2002): 233-239.
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