Curriculum Vitae
April 20, 2004
Name:
Fred G. Barker II
Office Address:
Brain Tumor Clinic, Cox 3
Massachusetts General Hospital, Boston, MA 02114
Education:
1981
B.S., Yale College, New Haven, CT, Summa cum laude
with Distinction in Molecular Biophysics and Biochemistry
and Classical Civilization
1985
M.D., Harvard Medical School, Boston, MA
Postdoctoral training:
Internship and Residency:
1985-86
Intern, Department of Surgery, Massachusetts General Hospital,
Boston, MA
1986-92
Resident, Neurosurgical Service, Massachusetts General Hospital,
Boston, MA
Clinical and Research Fellowships:
1992-93
1993-95
Fellow, Microvascular and Cranial Base Neurosurgery,
Department of Neurological Surgery,
University of Pittsburgh, Pittsburgh, PA
Fellow, Neuro-Oncology Service,
Department of Neurological Surgery,
University of California, San Francisco, CA
Licensure and Certification:
1995
Massachusetts Medical License
1998
American Board of Neurological Surgery
page 2
Academic Appointments:
1995
Instructor, Department of Surgery
Harvard Medical School, Boston, MA
2000
Assistant Professor, Department of Surgery
Harvard Medical School, Boston, MA
Hospital Appointments:
1995
Assistant in Neurosurgery
Massachusetts General Hospital, Boston, MA
1998
Assistant Visiting Neurosurgeon
Massachusetts General Hospital, Boston, MA
Committee Assignments:
2000
Search Committee, Neuro-Otologist
Department of Otolaryngology, Mass. Eye & Ear Infirmary
Professional Societies:
1992
1993
1996
1996
1996
2000
2002
2003
Community Service:
American Association of Neurological Surgeons
Section on History of Neurological Surgery, 1993Joint Section on Tumors, 1994Member, Executive Committee, 2003Chairman, History Subcommittee, 2003American Philological Association
New England Neurosurgical Society
Society for Neuro-Oncology
Communications Committee, 1998
Scientific Program Committee, 1999
American Society for Clinical Oncology
American College of Surgeons (Fellow)
ACS Oncology Group CNS Site Committee, 2002
Chair, 2004
ACS Commission on Cancer, CNS Disease Site Team (Leader)
1999
The Brain Tumor Society
Lecturer, “Treatment Options for Meningiomas”
Annual Meeting, Providence, RI (November 1999)
2002
The Brain Tumor Society
page 3
Lecturer, “Skull Base Surgery”
Annual Meeting, Newton, MA (September 2002)
Editorial Responsibilities:
1992
1995
1995
1999
2001
New England Journal of Medicine (ad hoc)
Cancer Research (ad hoc)
Neurosurgery (ad hoc)
Cancer (ad hoc)
Journal of Neuroimaging (ad hoc)
Awards and Honors:
1997
1994
1981
1981
1981
1980
1979
1977
Mahaley Clinical Research Award, Joint Section on Tumors,
American Association of Neurological Surgeons and Congress of
Neurological Surgeons
Henry Newman Award, San Francisco Neurological Society
(Clinical research)
Alpheus Henry Snow Prize (highest award of Yale College)
Noyes-Cutter Prize (translation of New Testament Greek)
Saybrook College Fellows' Prize (scholarship)
Merck Sharp and Dohme Award in Organic Chemistry
Phi Beta Kappa (Sophomore election)
Undergraduate President, 1980-1
National Merit Scholar
Research Funding:
Dana Foundation Research Fellowship, 1988-1990
NIH Training Grant CA 09291, 1993-1995
page 4
Report of teaching: Local
Harvard Medical School courses (undergraduate)
1985
Introduction to Clinical Medicine
Fourth-year preceptor; full-time, one month, 3 students
1988 and
1989
Neuroanatomy (New Pathway)
Laboratory Section Leader; 8 hr/week, 10 wk/yr, approx 20 students
1998-present Neurosurgery Clinical Elective (MGH)
Lead 1 hour tutorial on brain tumors for 4th year students
approx. 2 students/month, approx. 4 months per year
Harvard Medical School courses (Continuing Medical Education)
1998-present Tumors of the Central Nervous System
course intended for oncologists, radiation oncologists, neurologists
and neurosurgeons, approx 50-60/year
1998: led breakout session on Gliadel wafers (1 hour)
1999: lecture on role of surgery in treatment of malignant gliomas
moderated afternoon section on multidisciplinary glioma therapy
2000-3 lecture on role of surgery in treatment of malignant gliomas
Invited Teaching Presentations (Local and National):
Massachusetts General Hospital
1992
Surgical Service Combined Grand Rounds:
Fibrin glue in neurological surgery
1992
Neurosurgical Grand Rounds:
White 12 Service Report
1996-present Neurosurgical Grand Rounds
approx 4 presentations per year, 1 hour
audience: primarily resident and staff neurosurgeons & neurologists
series of lectures on basic and advanced statistics for clinical research
1997
2003
Neurology Grand Rounds
1 hour, approx 50 resident and staff neurologists
“Microvascular Decompression for Trigeminal Neuralgia and
Hemifacial Spasm”
Chiefs’ Council
30 min., approx 30 Chiefs of departments and senior administrators
page 5
“Centralization and Specialization in Intracranial Neurosurgery”
Brigham & Women’s Hospital
1997
Neurosurgery Grand Rounds, 1 hour
“Dr. Cushing Transplants a Brain: Neurosurgeons as Mad Scientists”
1998
Brain Tumor Research Group Rounds, 1 hour
“Age and prognosis in malignant glioma patients”
Massachusetts Eye and Ear Hospital
1991
ENT Grand Rounds: Craniofacial Resection, 1 hour
1996
Facial Nerve Clinico-pathologic Conference, 1 hour:
“Etiology of hemifacial spasm”
Presbyterian-University Hospital, Pittsburgh, PA
1993
Neurosurgery Grand Rounds, 1 hour
“Meta-analysis in neurosurgery: prophylactic antibiotics in craniotomy”
University of California, San Francisco
1994-5
Neurosurgery Grand Rounds, 45 minutes:
“Dr. Cushing transplants a brain: neurosurgeons as mad scientists in early
twentieth century popular culture”
“Microvascular decompression for trigeminal neuralgia and hemifacial
spasm: long term outcome in 1900 patients”
“Prognostic factors in neurosurgery: assessment and statistical
foundations”
American Association of Neurological Surgeons
1993
Invited seminar speaker, 30 minutes
“Phrenology and the American physician”
1997
Invited seminar speaker, 30 minutes
“Complication avoidance in cavernous sinus surgery”
2000
Invited seminar speaker, 30 minutes
“Cavernous malformations: when to treat”
page 6
2003-4
Invited seminar speaker, 30 minutes
“Evidence-based neurosurgery: studies of therapeutic benefit”
Congress of Neurological Surgeons
2001-02
Invited seminar speaker, 30 minutes
“Microvascular Decompression for Trigeminal Neuralgia – Long Term
Results”
John Martyn Harlow Frontal Lobe Symposium, Ludlow, VT
1998
Invited seminar speaker, 30 minutes
“Modern surgery of the frontal lobes in relation to the history of cerebral
localization (re: Phineas Gage)”
American Society of Clinical Oncology
2002
CNS Plenary Session discussant, 15 minutes
“Clinical trial design in brain tumors”, summarized 3 plenary session talks
Bibliography
Original Reports:
1. Frim DM, Barker FG, Poletti CE, Hamilton AJ. Postoperative low-dose heparin
decreases thromboembolic complications in neurosurgical patients. Neurosurgery
1992;30:830-833.
2. Barker FG. The Massachusetts General Hospital: early history, and neurosurgery to
1939. J Neurosurg 1993;79:948-959.
3. Yaremchuk MJ, Fiala TGS, Barker F, Ragland R. The effects of rigid fixation on
craniofacial growth of Rhesus monkeys. Plast Reconstr Surg 1994;93:1-10.
4. Barker FG. Efficacy of prophylactic antibiotics for craniotomy: a meta-analysis.
Neurosurgery 1994;35:484-492.
5. Barker FG, Tatter SB. Flow-directed placement of atrial catheter for ventriculoatrial
shunts. Technical note. Neurosurgery 1994;35:534536.
page 7
6. Barker FG, Ogilvy CS, Chin JK, Joseph MP, Pile-Spellman J, Crowell RM.
Transethmoidal transsphenoidal approach for embolization of a carotid-cavernous
fistula. Case report. J Neurosurg 1994;81:921-923.
7. Barker FG, Jannetta PJ, Bissonette DB, Shields PT, Larkins MV, Jho HD.
Microvascular decompression for hemifacial spasm. J Neurosurg 1995;82:201210.
8. Barker FG. Phineas among the phrenologists: the American Crowbar Case and
nineteenth century theories of cerebral localization. Historical vignette. J
Neurosurg 1995;82:672-682.
9. Chang SM, Barker FG, Larson DA, Bollen AW, Prados MD. Sarcomas subsequent to
cranial irradiation. Neurosurgery 1995;36:685-690.
10. Fick J, Barker FG, Dazin P, Westphale EM, Beyer EC, Israel MA. The extent of
heterocellular communication is predictive of bystander tumor cytotoxicity in
vitro. Proc Natl Acad Sci USA 1995;92:11071-11075.
11. Butler WE, Barker FG, Crowell RM. Polycystic kidney disease patients would
benefit from routine magnetic resonance angiographic screening for intracranial
aneurysms: a decision analysis. Neurosurgery 1996;38:506-516.
12. Barker FG, Prados MD, Chang SM, Davis RL, Gutin PH, Lamborn KR, Larson DA,
McDermott MW, Sneed PK, Wilson CB. Bromodeoxyuridine labeling index in
glioblastoma multiforme: relation to radiation response, age, and survival. Int J
Radiat Oncol Biol Phys 1996:34:803-808.
13. Barker FG, Ogilvy CS. Efficacy of prophylactic nimodipine for delayed ischemic
deficit after subarachnoid hemorrhage: a meta-analysis. J Neurosurg
1996;84:405-414.
14. Barker FG, Prados MD, Chang SM, Gutin PH, Lamborn KR, Larson DA, Malec MK,
McDermott MW, Sneed PK, Wara WM, Wilson CB. Radiation response and
survival in glioblastoma multiforme. J Neurosurg 1996;84:442-448.
15. Barker FG, Davis RL, Chang SM, Prados MD. Necrosis as a prognostic factor in
glioblastoma multiforme. Cancer 1996;77:1161-1166.
16. Barker FG, Jannetta PJ, Bissonette DB, Larkins MV, Jho HD. The long-term
outcome of microvascular decompression for trigeminal neuralgia. N Engl J Med
1996;334:1077-1083.
page 8
17. Barker FG, Jannetta PJ, Babu RP, Pomonis S, Bissonette DJ, Jho HD. Long-term
outcome after operation for trigeminal neuralgia in patients with posterior fossa
tumors. J Neurosurg 1996;84:818-825.
18. Barker FG. Analysis of the relationship between long-term operative success and a
transient or delayed operative side effect. Technical note. Neurosurgery
1996;39:412-416.
19. Ogilvy CS, Barker FG, Joseph MP, Cheney ML, Swearingen B, Crowell RM.
Transfacial transclival approach for midline posterior circulation aneurysms.
Neurosurgery 1996;39:736-742.
20. Barker FG, Jannetta PJ, Bissonette DJ, Jho HD. Trigeminal numbness and tic relief
after microvascular decompression for typical trigeminal neuralgia. Neurosurgery
1997;40:39-45.
21. Barker FG, Chang SM, Valk PE, Pounds TR, Prados MD. 18-Fluorodeoxyglucose
uptake and survival in recurrent malignant glioma. Cancer 1997;79:115-126.
22. Barker FG, Chang SM, Huhn SL, Davis RL, Gutin PH, McDermott MW, Wilson CB,
Prados MD. Age and the risk of anaplasia in MR-nonenhancing cerebral tumors.
Cancer 1997;80:936-941.
23. Chang SM, Barker FG, Huhn SL, Nicholas MK, Page M, Rabbitt J, Prados MD. A
phase II trial of high dose oral tamoxifen and subcutaneous interferon alpha-2a for
recurrent malignant glioma. J Neurooncol 1998;37:169-176.
24. Barker FG, Chang SM, Gutin PH, Malec MK, McDermott MW, Prados MD, Wilson
CB. Survival and functional status after resection of recurrent glioblastoma
multiforme. Neurosurgery 1998;42:709-723.
25. Swearingen B, Barker FG, Katznelson L, Biller BMK, Grinspoon S, Klibanski A,
Moayeri N, Black PMcL, Zervas NT. Long-term mortality after transsphenoidal
surgery and adjunctive therapy for acromegaly. J Clin Endocrinol Metab
1998;83:3419-3426.
26. Wackym PA, King WA, Barker FG, Poe DS. Endoscope-assisted vestibular
neurectomy. Laryngoscope 1998;108:1787-1793.
27. Swearingen B, Biller BMK, Barker FG, Katznelson L, Grinspoon S, Klibanski A,
Zervas NT. Long-term mortality after transsphenoidal surgery for Cushing’s
disease. Ann Int Med 1999;130:821-824.
page 9
28. Wackym PA, King WA, Poe DS, Meyer GA, Ojemann RG, Barker FG, Walsh PR,
Staecker H. Adjunctive use of endoscopy during acoustic neuroma surgery.
Laryngoscope 1999;109:1193-1201.
29. Simmons ML, Lamborn KR, Takahashi M, Chen P, Israel MA, Berger MS, Godfrey
T, Nigro J, Prados M, Chang S, Barker FG, Aldape K. Analysis of complex
relationships between age, p53, EGFR, and survival in glioblastoma patients.
Cancer Res 2001;61:1122-1128.
30. Barker FG, Amin-Hanjani S, Butler WE, Lyons S, Ojemann RG, Chapman PH,
Ogilvy CS. Temporal clustering of hemorrhages from untreated cavernous
malformations of the central nervous system. Neurosurgery 2001;49:15-24.
31. Barker FG, Simmons ML, Chang SM, Prados MD, Larson DA, Sneed PK, Wara
WM, Berger MS, Chen P, Israel MA, Aldape KD. EGFR overexpression and
radiation response in glioblastoma multiforme. Int J Radiat Oncol Biol Phys
2001;51:410-418.
32. Barker FG, Chang SM, Larson DA, Sneed PK, Wara WM, Wilson CB, Prados MD.
Age and radiation response in glioblastoma multiforme. Neurosurgery
2001;49:1288-1298.
33. Chang SM, Barker FG, Schmidt MH, Sloan AE, Kasper R, Phillips L, Shih K,
Hariharan S, Berger MS, and the Glioma Outcomes Investigators. Clinical trial
participation among patients enrolled in the Glioma Outcomes Project. Cancer
2002;94:2681-2687.
34. Barker FG. Efficacy of prophylactic antibiotic therapy in spinal surgery: a metaanalysis. Neurosurgery 2002;51:391-401.
35. Rabinov JD, Lee PL, Barker FG, Louis DN, Harsh GR, Cosgrove GR, Chiocca EA,
Thornton AF, Loeffler JS, Henson JW, Gonzalez RG. In vivo 3-T MR
spectroscopy in the distinction of recurrent glioma versus radiation effects: initial
experience. Radiology 2002;225:871-879.
36. Barker FG, Amin-Hanjani S, Butler WE, Ogilvy CS, Carter BS. In-hospital mortality
and morbidity after surgical treatment of unruptured intracranial aneurysms in the
United States, 1996-2000: the effects of hospital and surgeon volume.
Neurosurgery 2003;52:995-1009.
37. Olivi A, Grossman SA, Tatter S, Barker F, Judy K, Olsen J, Bruce J, Hilt D, Fisher J,
Piantadosi S. Dose escalation of carmustine in surgically implanted polymers in
patients with recurrent malignant glioma: a New Approaches to Brain Tumor
Therapy CNS Consortium trial. J Clin Oncol 2003;21:1845-1849.
page 10
38. Chang SM, Parney IF, McDermott M, Barker FG, Schmidt MH, Huang W, Laws ER
Jr, Lillehei KO, Bernstein M, Brem H, Sloan AE, Berger M, and the Glioma
Outcomes Investigators. Perioperative complications and neurological outcome
of first versus second craniotomy among patients enrolled in the Glioma
Outcomes Project. J Neurosurg 2003;98:1175-1181.
39. Kalkanis SN, Eskandar EN, Carter BS, Barker FG. Microvascular decompression
surgery in the United States, 1996-2000: mortality rates, morbidity rates, and the
effects of hospital and surgeon volume. Neurosurgery 2003;52:1251-1262.
40. Hoh BL, Rabinov JD, Pryor JC, Carter BS, Barker FG. In-hospital mortality and
morbidity after endovascular treatment of unruptured intracranial aneurysms in
the United States, 1996-2000: the effect of hospital and physician volume. AJNR
Am J Neuroradiol 2003;24:1409-1420.
41. Barker FG, Butler WE, Lyons S, Cascio E, Ogilvy CS, Loeffler JS, Chapman PH.
Dose-volume prediction of radiation-related complications after proton beam
radiosurgery for cerebral arteriovenous malformations. J Neurosurg 2003;99:254263. With accompanying editorial, see below for reply.
42. Barker FG, Carter BS, Ojemann RG, Jyung RW, Poe DS, McKenna MJ. Surgical
excision of acoustic neuroma: patient outcome and provider caseload.
Laryngoscope 2003;113:1332-1343.
43. Weber DC, Chan AW, Bussiere MR, Harsh GR 4th, Ancukiewicz M, Barker FG,
Thornton AT, Martuza RL, Nadol JB Jr, Chapman PH, Loeffler JS. Proton beam
radiosurgery for vestibular schwannoma: tumor control and cranial nerve toxicity.
Neurosurgery 2003;53:577-588.
44. Barker FG, Klibanski A, Swearingen B. Transsphenoidal surgery for pituitary
tumors in the United States, 1996-2000: mortality, morbidity and the effect of
hospital and surgeon volume. J Clin Endocrinol Metab 2003;88:4709-4719.
45. Eskandar EN, Flaherty A, Cosgrove GR, Shinobu LA, Barker FG. Surgery for
Parkinson disease in the United States, 1996-2000: practice patterns, short-term
outcome and hospital charges in a nationwide sample. J Neurosurg 2003;99:863871.
46. Ramsey MJ, McKenna MJ, Barker FG. Superior semicircular canal dehiscence
syndrome. J Neurosurg 2004;100:123-4.
47. Barker FG, Amin-Hanjani S, Butler WE, Hoh BL, Rabinov JD, Pryor JC, Ogilvy CS,
Carter BS. Age-dependent differences in short-term outcome after surgical or
endovascular treatment of unruptured intracranial aneurysms in the United States,
1996-2000. Neurosurgery 2004;54:18-30.
page 11
48. Smith ER, Butler WE, Barker FG. In-hospital mortality after ventriculoperitoneal
shunt procedures in the United States, 1998-2000: relation to hospital and
surgeon volume of care. J Neurosurg 2004;100(Pediatrics 2):90-7. With
accompanying editorial and reply.
49. Amin-Hanjani S, Ogilvy CS, Barker FG. Does intracisternal thrombolysis prevent
vasospasm following aneurysmal subarachnoid hemorrhage? Neurosurgery
2004;54:326-34.
50. Smith ER, Butler WE, Barker FG. Craniotomy for resection of pediatric brain
tumors in the United States, 1988-2000: the effect of provider caseload and
progressive centralization and specialization of care. Neurosurgery 2004;54:553565.
51. Barker FG. Craniotomy for resection of metastatic brain tumors in the United States,
1988-2000: decreasing mortality and the effect of provider caseload. Cancer
2004;100:999-1007.
52. Rabinov JD, Barker FG, McKenna MJ, Curtin HD. Virtual cisternoscopy: 3D
models of the cerebellopontine angle for lesions related to the cranial nerves. In
press, Skull Base Surgery.
53. Barker FG, Linskey ME. History of the AANS/CNS Joint Section on Tumors and
preface to the 20th anniversary Journal of Neuro-Oncology special issue. In press,
J Neurooncol.
54. Ghogawala Z, Benzel EC, Amin-Hanjani S, Barker FG, Harrington JF, Magge SN,
Strugar J, Coumans J-V, Borges LF. Prospective outcomes evaluation of
decompression with or without instrumented fusion for lumbar stenosis with
degenerative grade I spondylolisthesis. In press, J Neurosurg.
55. Barker FG, Amin-Hanjani S. The changing neurosurgical workload in the United
States, 1988-2001: craniotomy other than trauma in adults. In press,
Neurosurgery.
Proceedings of Meetings:
1. Barker FG, Chen P, Furman F, Aldape KD, Edwards MSB, Israel MA. p16 mutations
and deletions in human brain tumors. J Neurooncol 1997;31:17-23.
2. Zervas NT, Swearingen B, Barker FG. Long-term outcome after transsphenoidal
surgery for pituitary adenomas. Clin Neurosurg 1999;45:48-56.
page 12
Review Articles and Book Chapters:
1. Barker FG, Heros RC. Clinical aspects of vasospasm. Neurosurg Clin N Am
1990;1:277-288.
2. Barker FG, Ojemann RG. Surgical approaches to tumors of the posterior fossa cranial
nerves (excluding acoustic neuroma). In: Barrow DL, ed. Surgery of the cranial
nerves of the posterior fossa (Neurosurgical Topics 13). [Chicago]: American
Association of Neurological Surgeons, 1993:289-305.
3. Barker FG, Israel MA. Molecular genetics of brain tumors. Neurol Clin N Am
1995;13:701-721.
4. Barker FG, Jannetta PJ. Nonpainful syndromes of the lower cranial nerves (excluding
hemifacial spasm). In: Tindall GT, Barrow DL, Cooper PR, eds. The practice of
neurosurgery. Baltimore: Williams & Wilkins, 1996;3:2965-2972.
5. Barker FG, Israel MA. Molecular genetics of gliomas. In: Berger MS, Wilson CB,
eds. Textbook of gliomas. Philadelphia: W. B. Saunders, 1997:39-51.
6. Barker FG, Huhn SL, Prados MD. Clinical characteristics of long-term survivors of
glioma. In: Berger MS, Wilson CB, eds. Textbook of gliomas. Philadelphia:
W. B. Saunders, 1997:710-722.
7. Barker FG, Gutin PH. Surgical techniques for gliomas. In: Berger MS, Wilson CB,
eds. Textbook of gliomas. Philadelphia: W. B. Saunders, 1997:349-360.
8. Barker FG, Israel MA. Brain tumors: epidemiology, molecular and cellular
abnormalities. In: Bertino JR, ed. Encyclopedia of cancer. San Diego:
Academic Press, 1996;1:156-164.
9. Ogilvy CS, Barker FG. Head injury. In Bogousslavsky J, Fisher M, eds. Textbook of
neurology. Boston: Butterworth Heinemann, 1998;711-725.
10. Loeffler JS, Barker FG, Chapman PH. Role of radiosurgery in the management of
central nervous system metastases. Cancer Chemotherapy Pharmacol 1999;43
Suppl:S11-14.
11. Jannetta PJ, McLaughlin MR, Barker FG, Kalia KK: Microvascular decompression.
In: May M, Schaitkin BM, eds. The facial nerve: May’s second edition. New
York: Thieme, 2000:483-489.
page 13
12. Barker FG. Epidemiology of traumatic brain injury. In: Batchelor TT, Cudkowicz
ME, eds. Principles of Neuroepidemiology. Boston: Butterworth Heinemann,
2001;237-263.
13. Ohta S, Israel MA, Barker FG. Brain tumors: epidemiology and molecular and
cellular abnormalities. In: Bertino JR, ed. Encyclopedia of cancer. San Diego:
Academic Press, ed 2. 2002;1:279-286.
14. Barker FG, Sztramski P. Surgery for brain tumors. In: Prados MD, ed. Brain
Cancer. Hamilton, ON: BC Decker, 2002:238-261.
15. Smith ER, Tarbell NJ, Ebb DH, Barker FG. Pilocytic astrocytomas. In: Clinical
Neuro-oncology. Berger MS, Prados MD, eds. In press, Elsevier, 2004.
16. Chang SM, Barker FG, Tihan T. Pineoblastoma. In: Clinical Neuro-oncology.
Berger MS, Prados MD, eds. In press, Elsevier, 2004.
17. Barker FG, Liebsch NJ. Chordomas and chondrosarcomas of the skull base. In
Black PMcL, Loeffler JS. Cancer of the Nervous System. In press, Lippincott,
2004.
18. Fine H, Barker FG, Markert J, Loeffler JS. Neoplasms of the central nervous system.
In DeVita VT Jr, Hellman S, Rosenberg SA. Cancer: Principles & Practice of
Oncology. Philadelphia: Lippincott Williams & Wilkins, in press.
Editorial Comments and Letters:
1. Barker FG. Reply to letter by Savitz MH and Malis LI. Neurosurgery 1995;36:1057.
[Regarding Barker FG: Efficacy of prophylactic antibiotics for craniotomy: a
meta-analysis. Neurosurgery 1994; 35:484-92.]
2. Barker FG, Ojemann RG. Comment. Neurosurgery 1997;40:275. [Regarding Kaba
SE, DeMonte F, Bruner JM et al.: The treatment of recurrent unresectable and
malignant meningiomas with interferon alpha-2b. Neurosurgery 1997;40:271-5.]
3. Ojemann RG, Barker FG. Comment. Neurosurgery 1997;40:481. [Regarding
Matthies C, Samii M, Krebs S: Management of vestibular schwannomas
(acoustic neuromas): radiological features in 202 cases — their value for
diagnosis and their predictive importance. Neurosurgery 1997;40:469-82.]
4. Barker FG, Ojemann RG. Comment. Neurosurgery 1997;41:93. [Regarding Polin
RS, Shaffrey ME, Bogaev CA, et al. Decompressive bifrontal craniectomy in the
page 14
treatment of severe refractory posttraumatic cerebral edema. Neurosurgery
1997;41:84-94.]
5. Barker FG. Letter. Neurosurgery 1997;41:999. [Regarding Sanan A, Haines SJ.
Repairing holes in the head: a history of cranioplasty. Neurosurgery
1997;40:588-603.]
6. Barker FG, Ojemann RG. Comment. Neurosurgery 1998;42:240-1. [Regarding Day
JD, Fukushima T. The surgical management of trigeminal neuromas.
Neurosurgery 1998;42:233-40.]
7. Chapman PH, Barker FG. Comment. Neurosurgery 1998;43:807. [Regarding
Resnick DK, Levy EI, Jannetta PJ. Microvascular decompression for pediatric
onset trigeminal neuralgia. Neurosurgery 1998;43:804-8.]
8. Barker FG. Comment. Neurosurgery 1998;43:1117. [Regarding Kureshi SA,
Wilkins RH. Posterior fossa reexploration for persistent or recurrent trigeminal
neuralgia or hemifacial spasm: surgical findings and therapeutic implications.
Neurosurgery 1998;43:1111-7.]
9. Amin-Hanjani S, Barker FG, Ogilvy CS. Reply to letter. Neurosurgery 1999;44:4245. [Regarding Amin-Hanjani S, Ogilvy CS, Candia GJ, et al. Stereotactic
radiosurgery for cavernous malformations: Kjellberg’s experience with proton
beam therapy in 98 cases at the Harvard Cyclotron. Neurosurgery 1998;42:122936.]
10. Barker FG. Comment. Neurosurgery 2000;46:361-2. [Regarding Lee SH, Levy EI,
Scarrow AM, et al. Recurrent trigeminal neuralgia attributable to veins after
microvascular decompression. Neurosurgery 2000;46:356-62.]
11. Barker FG. The article reviewed. Oncology (Huntington, NY) 2001;15:1158-1163.
[Regarding Sawaya RE. Considerations in the diagnosis and management of
brain metastases. Oncology 2001;15:1144-1158.]
12. Barker FG. Comment. Neurosurgery 2001;49:855-6. [Regarding Ishikawa M et al.
Delayed resolution of residual hemifacial spasm after microvascular
decompression operations. Neurosurgery 2001;49:847-56.]
13. Barker FG. Comment. Neurosurgery 2001;49:1370. [Regarding Mooij JJA, Mustafa
MK, van Weerden TW. Hemifacial spasm: intraoperative electromyographic
monitoring as a guide for microvascular decompression. Neurosurgery
2001;49:1365-71.]
14. Barker FG, Amin-Hanjani S, Loeffler JS. Comment. [Regarding Chang SD et al.
Cavernous Malformation Radiosurgery.] In: Contemporary Stereotactic
page 15
Radiosurgery: Technique and Evaluation. Pollock BE, ed. Armonk, NY: Futura
Publishing. In press, 2002.
Educational materials
SANS VII (Self Assessment in Neurosurgery, 7th edition), Congress of Neurological
Surgeons, 2002
Editor, Tumor section
(Educational material for self-preparation for oral neurosurgery boards
examination)
Abstracts (only for works not yet published in full):
A1. Barker FG. Treatment of the open brain wound in America, 1810-1880 [abstract]. J
Neurosurg 1993;78:364A. Platform presentation, Section on History of
Neurological Surgery, American Association of Neurological Surgeons, Boston,
MA, 1993, and American Association for the History of Medicine, Louisville,
KY, 1993. Proc Am Assoc Hist Med 1993;66:6 [abstr].
A2. Barker FG. Dr. Cushing transplants a brain: neurosurgeons as mad scientists in
early 20th century popular culture. Platform presentation, Section on History of
Neurological Surgery, American Association of Neurological Surgeons, San
Diego, CA, 1994. J Neurosurg 1994;80:405A [abstr].
A3. Barker FG, Tatter SB, Black PMcL. Harvey Cushing's first and last meningioma
operations: 37 years of progress in operative and perioperative management.
Platform presentation, Section on History of Neurological Surgery, American
Association of Neurological Surgeons, Orlando, FL, 1995. J Neurosurg
1995;82:370A [abstr].
A4. Barker FG. Desperate remedies: surgical treatment of epilepsy in America, 18101900 [abstract]. Proc AANS Annual Meeting 1995. Poster presentation,
American Association of Neurological Surgeons, Orlando, FL, 1995.
A5. Chang S, Barker F, Huhn S, Nicholas M, Norman D, Rabbitt J, Page M, Graney W,
Prados M. A pilot study of RMP-7 and carboplatin in patients with recurrent
malignant glioma. Proc Am Soc Clin Oncol (ASCO) 1995;14:152 [abstr].
A6. Barker FG, Chang SM, Larson DA, Sneed PK, Lamborn KR, Gutin PH, McDermott
MW, Prados MD. Radiation response as a predictor of chemosensitivity in
glioblastoma multiforme. Poster presentation, Congress of Neurological
Surgeons, San Francisco, CA, 1995, and 11th International Conference on Brain
Tumor Research and Therapy, Napa, CA, 1995. J Neurooncol 1996;28:65 [abstr].
page 16
A7. Spangler WJ, Frim DM, Tatter SB, Barker FG, Cosgrove GR. Clinical impact of
stereotactic brain biopsy: a retrospective review of 484 cases. Platform
presentation, General Scientific Session VI, American Association of
Neurological Surgeons, Minneapolis, MN, 1996. J Neurosurg 1996;84:350A351A [abstr].
A8. Barker FG. Frontier neurosurgery: brain surgery in America's hinterlands, 1810 1880. Platform presentation, Section on History of Neurological Surgery,
American Association of Neurological Surgeons, Minneapolis, MN, 1996. J
Neurosurg 1996;84:361A-362A [abstr].
A9. Barker FG, Chang SM, Prados MD, Gutin PH. Response to carmustine (BCNU),
tumor control, and survival in recurrent glioblastoma multiforme. Proc Am Soc
Clin Oncol (ASCO) 1996;15:161 [abstr]. Poster presentation, Society for NeuroOncology, Santa Fe, NM, 1996; Proc SNO 1st Annual Meeting, abstract 28
[abstr].
A10. Siddik ZH, Grous JJ, Chang S, Barker F, Huhn S, Nicholas M, Rabbitt J, Page M,
Graney WF, Prados M. Pharmacokinetics of carboplatin and RMP-7 in patients
with recurrent malignant glioma. Poster presentation, American Society for
Clinical Oncology, Philadelphia, PA, 1996. Proc Am Soc Clin Oncol (ASCO)
1996;15:477 [abstr].
A11. Eskandar E, Carter BS, Frim DM, Barker FG. Efficacy of prophylactic antibiotics
for posttraumatic CSF fistulae: a meta-analysis. Platform presentation, Section
on Trauma, Congress of Neurological Surgeons, Montreal, PQ, 1996.
Neurosurgery 1996;39:636 [abstr].
A12. Barker FG, Swearingen B. Craniotomy for idiocy: the rise and fall of a
neurosurgical operation. Platform presentation, Section on History of
Neurological Surgery, American Association of Neurological Surgeons, Denver,
CO, 1997. J Neurosurg 1997;86:383A [abstr].
A13. Tang G, Barker FG, Swearingen B, Zervas NT. Prolactinomas in men: clinical
features and long-term outcome after transsphenoidal resection. Platform
presentation, Scientific Session IV, American Association of Neurological
Surgeons, Denver, CO, 1997. J Neurosurg 1997;86:361A [abstr].
A14. Barker FG. “Stable disease” rates in phase II trials of inactive agents in recurrent
malignant glioma. Proc Am Soc Clin Oncol (ASCO) 1997;16:396a [abstr].
A15. Barker FG, Amin-Hanjani S, Butler WE, Lyons SL, Ogilvy CS, Ojemann RG,
Chapman PH. Risk of rebleeding after first hemorrhage from cerebral cavernous
malformations: natural history and response to proton beam radiosurgery.
Platform presentation, American Academy of Neurological Surgery, Banff,
page 17
Alberta, 1997. Platform presentation, Joint Section on Cerebrovascular Surgery,
Congress of Neurological Surgeons, New Orleans, LA, 1997. Neurosurgery
1997;41:720 [abstr].
A16. Barker FG, Chang SM, Gutin PH, McDermott MW, Wilson CB, Prados MD. Age,
extent of resection, and survival in glioblastoma multiforme. Platform
presentation, Joint Section on Tumors, Congress of Neurological Surgeons, New
Orleans, LA, 1997. Neurosurgery 1997;41:726-7 [abstr].
A17. Barker FG. Meta-analysis of locally applied opiates during lumbar discectomy.
Platform presentation, Joint Section on Spine, Congress of Neurological
Surgeons, New Orleans, LA, 1997. Neurosurgery 1997;41:745 [abstr].
A18. Barker FG, Chiocca EA. Phase I trial design for oncolytic virus therapy of brain
tumors. 12th International Conference on Brain Tumour Research and Therapy,
Oxford, UK, 1997. J Neurooncol 1997;35 Suppl 1:S7 [abstr].
A19. Butler WE, Barker FG, Doherty C. Compensation for brain shift with dynamic
frameless stereotaxy. Oral Poster, Congress of Neurological Surgeons, Seattle,
WA, 1998. Proc CNS Annual Meeting 1998:495-6 [abstr].
A20. Barker FG, Amin-Hanjani S, Butler WE, Lyons S, Ogilvy CS, Loeffler J, Chapman
PH. Complication rates after radiosurgery for cavernous malformations. New
England Neurosurgical Society, 1998. Section on Cerebrovascular Surgery,
Congress of Neurological Surgeons, Seattle, WA, 1998. Neurosurgery
1998;43:670 [abstr].
A21. Barker FG. Efficacy of prophylactic antibiotics in cerebrospinal shunt surgery: a
meta-analysis. Section on Pediatric Neurosurgery, Congress of Neurological
Surgeons, Seattle, WA, 1998. Neurosurgery 1998;43:694 [abstr].
A22. Staecker H, Nadol JB Jr, Barker FG, Ojemann RG, McKenna MJ. Long term
followup of acoustic neuromas by serial MRI scans: clinical implications for
treatment in an elderly and surgical high risk population. Oral Poster, CNS,
Boston, MA, October, 1999. Proc CNS Annual Meeting 1999:329-30 [abstr].
A23. Barker FG, Smith E. Anterior cervical discectomy with and without fusion: a
meta-analysis of the randomized trials. Poster, CNS, Boston, MA, October, 1999.
Proc CNS Annual Meeting 1999:593 [abstr].
A24. Asher AL, Anderson F, Stolzenbach K, Barker F, Limentani S, Laws E, Glioma
Outcomes Investigators. Perioperative differences between community and
academic medical centers in the Glioma Outcomes Project. Poster, Joint Section
on Tumors (AANS/CNS), San Francisco, CA, April, 2000. Fourth Biennial
Satellite Symposium Proc 2000:54 [abstr].
page 18
A25. Barker FG, Poe DS, McKenna MJ, Nadol JB Jr, Ronner SF, Ojemann RG.
Efficacy of endoscopically assisted IAC waxing in reducing CSF leak after
suboccipital craniotomy for acoustic. Poster, CNS, San Antonio, TX, October,
2000. Proc CNS Annual Meeting 2000;2:222 [abstr].
A26. Hariharan S, Landolfi J, More J, Barker F, Hochberg F, Chang S, Sloan A, Phillips
L, Anderson F, and the Glioma Outcomes Project Investigators. Alternative
therapy use by malignant glioma patients: data from the Glioma Outcomes
Project. Platform presentation, Society for Neuro-Oncology, Chicago, IL,
November, 2000. Neuro-Oncology 2000;2:268 [abstr].
A27. Aldape K, Takahashi M, Lamborn K, Malec M, Chang S, Prados M, Barker F,
Berger M. Cyclin-dependent kinase inhibitors (cdki’s) in glioblastoma:
correlations with proliferation, radiation response and survival. Poster, Society
for Neuro-Oncology, Chicago, IL, November, 2000. Neuro-Oncology 2000;2:246
[abstr].
A28. Barker FG, McKenna M, Poe D, Nadol J, Martuza R, Ojemann R. Transtympanic
electrode placement as a risk factor for postoperative bacterial meningitis after
acoustic neuroma resection. Platform presentation, North American Skull Base
Surgery Society, Orlando, FL, March, 2001. Poster, AANS, Toronto, ON, April,
2001. Skull Base 11 Suppl 1:3-4 [abstr].
A29. Barker FG, McKenna M, Poe D, Nadol J, Chapman P, Martuza R, Ojemann RG.
Pediatric acoustic neuromas: NF2 and sporadic tumors. Platform presentation,
Pediatric Section, CNS, San Diego, CA, October, 2001. Neurosurgery
2001;49:533 [abstr]. Poster, North American Skull Base Society, Orlando, FL,
March, 2001. Skull Base 11 Suppl 1:3 [abstr].
A30. Barker FG. Cellular telephones and brain tumors: a meta-analysis. Oral Poster,
CNS, San Diego, CA, October, 2001. Poster, Society for Neuro-Oncology,
Washington, DC, November 2001. Poster, Fifth Biennial Brain Tumor Satellite
Symposium, Joint Section on Tumors (CNS/AANS), Chicago, IL, April 2002.
Neuro-Oncology 2001;3:283-284 [abstr].
A31. Barker FG, Chang S, Larson D, Sneed P, Wara W, Wilson C, Berger M, Prados M,
Aldape K. p21 immunoreactivity and imaging-assessed radiosensitivity in
glioblastoma multiforme. Poster, AACR, San Francisco, CA, April, 2002. Proc
AACR 2002;43:624 (#3096) [abstr]. Poster, Society for Neuro-Oncology, San
Diego, CA, November, 2002. Proc SNO 2002, Abstract A2 [abstr].
A32. Barker FG, Chang SM, Simmons ML, Prados MD, Berger MS, Aldape KD. Cyclin
A as a prognostic factor in glioblastoma multiforme. Poster, Society for Neuro-
page 19
Oncology, San Diego, CA, November, 2002. Proc SNO 2002, Abstract A2
[abstr].
A33. Barker FG, Chang SM, Prados MD, Larson DA, Sneed PK, Wara WM, Berger MS,
O’Campo JR, Aldape KD. PTEN immunohistochemistry, survival, and in vivo
radiation response in glioblastoma multiforme. Platform presentation, Fifth
Biennial Brain Tumor Satellite Symposium, Joint Section on Tumors
(CNS/AANS), Chicago, IL, April 2002, Abstract 24 [abstr].
A34. Kalkanis SN, Ojemann RG, McKenna MJ, Poe DS, Nadol JR, Barker FG. Subtotal
resection of acoustic neuromas: long-term results. Platform Presentation, Joint
Section on Tumors, CNS, Philadelphia, PA, September, 2002. Neurosurgery
2002;51:552 [abstr].
A35. Barker FG. Dr. Cushing (from the audience). Platform Presentation, Scientific
Session I, AANS, San Diego, CA, April, 2003. J Neurosurg 2003;98:683 [abstr].
A36. Barker FG. Hospital and surgeon caseload and outcome after craniotomy for brain
tumor in the US from 1996 to 2000. Platform Presentation, Joint Section on
Tumors, AANS, San Diego, CA, April, 2003. J Neurosurg 2003;98:707 [abstr].
A37. Henson JW, Braga TA, Lee PL, Barker FG, Gonzalez RG, Lev MH. Diffusion
abnormalities following resection of malignant glioma. Neurology 2003;60 Suppl
1:A16 [abstr].
A38. Curry WT, Butler WE, Barker FG. Cerebrospinal fluid shunting procedures for
benign intracranial hypertension: rising incidence in the United States, 19882000. Platform Presentation, Council of State Neurosurgical Societies, CNS,
Denver, CO, October, 2003. Neurosurgery 2003;53:485 [abstr].
A39. Amin-Hanjani S, Barker FG. The changing neurosurgical workload, 1988-2000:
craniotomy other than trauma in adults. Platform Presentation and winner of
CSNS Young Neurosurgeon Award (to Dr. Amin-Hanjani), Council of State
Neurosurgical Societies, CNS, Denver, CO, October, 2003. Neurosurgery
2003;53:486-7 [abstr].
A40. Barker FG. Decreasing mortality and progressive centralization of surgical
treatment of primary brain tumors in the United States, 1988-2000. Platform
Presentation, Section on Tumors II, CNS, Denver, CO, October, 2003.
Neurosurgery 2003;53:506 [abstr]. Poster Presentation, Society for NeuroOncology, Keystone, CO, November, 2003. Neuro-Oncology 2003;5:330 [abstr].
A41. Curry WT, McDermott MW, Carter BS, Barker FG. Craniotomy for meningioma
in the United States, 1988-2000: decreasing mortality and the effect of hospital
page 20
volume. Platform Presentation, Scientific Session I, AANS, Orlando, FL, May,
2004. J Neurosurg 2004;100:773-4 [abstr].
A42. Ghogawala Z, Benzel EC, Amin-Hanjani S, Barker FG, Harrington F, Magge SZ,
Strugar J, Bartolomei J, Coumans JV, Borges LF. Prospective comparison of
surgical outcomes after laminectomy with or without instrumented fusion for
lumbar stenosis with grade I spondylolisthesis. Platform Presentation, Scientific
Session II, AANS, Orlando, FL, May, 2004. J Neurosurg 2004;100:775-6 [abstr].
A43. Smith ER, Butler WE, Barker FG. Pediatric subspecialization within American
neurosurgery between 1988 and 2001: a population-based study. Platform
Presentation, Scientific Session III, AANS, Orlando, FL, May, 2004. J Neurosurg
2004;100:778 [abstr].
A44. Barker FG. Resuscitation by urgent posterior fossa decompression under artificial
respiration: an unpublished manuscript by Harvey Cushing. Platform
Presentation, Plenary Session II, AANS, Orlando, FL, May, 2004. J Neurosurg
2004;100:784-5 [abstr].