CV Arkadopoulos

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BRIEF CURRICULUM VITAE
Νikolaos Arkadopoulos, M.D., Ph.D, FACS
Associate Professor of Surgery,
University of Athens Medical School
PERSONAL INFORMATION
Address:
Tel:
Fax:
Email:
4th Department of Surgery, Attikon University Hospital
1 Rimini str., 12462 Chaidari, Athens, Greece
+30-210-5831386, cell phone +30-6937106217
+30-210-5326412
narkado@otenet.gr
Born in1968 in Heraklion, Greece.
Married to Electra Nicolaidou, MD, PhD, Ass. Professor of
Dermatology. Father of two daughters.
EDUCATION
1980-1985
1985-1991
1st high School and lyceum of Elefsina, graduation with grade
“Excellent”
M.D., National and Kapodistrian University of Athens Medical
School, Athens,Greece, Magna Cum Laude
POSTGRADUATE
1993-1996 and
1997-1999
1995-1997
1999-2000
1999
Resident in General Surgery, 2nd Department of Surgery,
Aretaieio University Hospital, Athens, Greece.
Research Fellow, Department of Surgery, Cedars Sinai Medical
Center, UCLA School of Medicine, Los Angeles, CA, USA
Military service as a surgeon in the “251 General Air Force
Hospital” Athens, Greece.
Ph.D., National and Kapodistrian University of Athens Medical
School, Athens, Greece Grade: “Excellent”
Foreign Languages Fluent in oral and written English and French
ACADEMIC APPOINTMENTS
2002-2007
2007-Present
Lecturer of Surgery, National and Kapodistrian University of
Athens Medical School, Athens,Greece.
Assistant Professor of Surgery, National and Kapodistrian
University of Athens Medical School, Athens,Greece
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HOSPITAL APPOINTMENTS
2000-2002
2002-2010
2010-present
Attending Surgeon, Dynant Hopsital, Athens, Greece.
Attending Surgeon, 2nd Department of Surgery, Aretaieio
University Hospital, Athens,Greece.
Attending Surgeon, 4nd Department of Surgery, Attikon
University Hospital, Chaidari, Athens,Greece.
LICENSURE
1991
1999
Prefecture of Athens, Greece #38355
Prefecture of Athens, Greece, #15127, 11-10-99, Specialisation
in Surgery
PROFESSIONAL &
SCIENTIFIC SOCIETIES
American College of Surgeons
International Society of Surgery (ISS/SIC)
Hellenic Surgical Society
Hellenic Society of Pancreatology
Hellenic Association for the Study of Liver
Athens Medical Association
HONORS AND AWARDS
I have received 37 national and international awards among which are:
1995
Prize for the best experimental research paper of the
European Congress of the International Hepato-PancreatoBiliary Association for the abstract entitled «Experimental
xenotransplantation of fresh isolated and cryopreserved pig
hepatocytes in case of toxic liver failure. Comparison of two
methods
1997
Young Investigator Award of the American Association for
the Study of Liver Diseases, Chicago, USA
2005
ISS/SIC Lloyd Nyhus Prize for the best free paper in
gastrointestinal surgery, International Surgical Week 2005
and 41st World Congress of Surgery of ISS/SIC, for the abstract
entitled «Ischemic preconditioning confers antiapoptotic
protection during major hepatectomies performed under
complete vascular exclusion of the liver» (World Journal of
Surgery 2005; 29:1696)
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2012
International Guest Scholarship by the American College of
Surgeons
RESEARCH
I was first involved in research during my senior years in Medical School. Since then
I have completed a significant number of research projects that are reflected in my
articles in peer-reviewed journals and my abstracts in national and international
meetings. Over the years my research projects have included:
1. Anatomical studies of the thyroid, parathyroids and adrenal glands.
2. Historical studies
3. Clinical and experimental studies in liver surgery and liver transplantation
4. Clinical and experimental studies in pancreatic surgery
5. Clinical studies in breast surgery
6. Experimental models of liver failure in large and small animals
7. Experimental studies in isolation and transplantation of hepatocytes and
pancreatic islets
8. Experimental and clinical studies of liver support systems
9. Experimental and clinical studies in laparoscopic surgery
10. Studies in the nutrition of critically ill patients
My current research work focuses on the following areas:
1. Experimental application of liver support methods in a large animal model of posthepatectomy liver failure that I have developped. The aim of this research is to find a
method of liver support that would be suitable for patients that fall into liver
dysfunction or liver failure after extensive liver surgery. This is a particularly
important in Greece where HBV-related liver cancer is prevalent and the lack of liver
donors makes liver transplantation unavailable in a timely manner. The two liver
support strategies that I have been testing is the hepatocyte-based bioartificial liver
and the peritoneal albumin dialysis, an innovative method that we developed in the
lab of the 2nd Department of Surgery in Aretaieion Hospital. Results from this
ongoing research have already been published in major journals.
2. Experimental application of antioxidants in order to reduce ischemia/reperfusion
injury of the liver in a large animal model of hemorrhagic shock and resuscitation.
Experiments of this project are ongoing and have already yielded promising results.
3. Clinical application of methods to reduce ischemia/reperfusion injury of the liver
remnant during liver surgery. Under this project I have already tested in small clinical
trials the value of ischemic preconditioning, intermittent clamping of the portal triad,
and use of antioxidants. Currently I am testing novel combinations of antioxidants in
hepatectomies performed under selective vascular exclusion of the liver, i.e. occlusion
of the hepatoduodenal ligament and the extrahepatic trunks of the major hepatic veins
without interruption of the flow in the inferior vena cava.
4. Study of circulating tumor cells during liver surgery.
5. Clinical applications of radio-guided breast surgery. This research includes a
protocol of sentinel lymph node biopsy for breast canncer under local anesthesia on
an outpatient basis and another protocol of radio guided localization of occult breast
lesions.
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TEACHING CONTRIBUTIONS
2002-present
Teaching of 4th and 6th year students of medicine in
amphitheatres and practical tutoring in patient wards (3-6
hours/week) and operating theatres according to the official
program of the University of Athens
2002-present
2002-present
Training of surgical residents in operations
Supervision of 12 PhD candidates in the experimental surgical
laboratory of the 2nd Department of Surgery, University of
Athens Medical School
Organization for the first time in Greece of the series of
“sentinel lymph node biopsy seminars and hands on courses”in
collaboraation with University College London and training of
50 Greek surgeons
10/2010-present
LECTURES
1989-present
Invited lecturer in a total of 75 meetings and congresses,
regional (33), national (33) and international (9) on
hepatobiliary and pancreatic surgery, endocrine surgery, breast
surgery, liver support technology, experimental surgery and
suurgical critical care
MANUSCRIPT REVIEW
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American Journal of Transplantation
European Surgical Research
BMC Gastroenterology
Journal of Postgraduate Medicine
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BIBLIOGRAPHY
SUMMARY OF INTERNATIONAL PUBLICATIONS*
Number
Full articles in
international journals
indexed by the
Science Citation Index
(SCI-MEDLINE)
Publications in
congress proceedings
and book chapters
Abstracts
115
Sum of
impact
factors
(Journal
citation
index
2010)
262
Citations (as
indexed in
SCOPUS
1100
H index
16
15
-
-
-
88
-
-
-
Among the full articles 36% are experimental papers, 37% are retrospective analyses
of case-series or prospective clinical trials, 9% are reviews, 16% are case reports and
3% are letters.
Regarding the subjects of the papers, 71% deal with hepatobilary and pancreatic
surgery and the rest deals with endocrine surgery, breast surgery, gynecological
ssurgery, vascular surgery, surgical critical care, etc.
SUMMARY OF GREEK PUBLICATIONS
Full articles in Greek journals:
Abstracts in Greek meetings:
Chapters in books:
29
111
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