Topic – Market Survey of Anti Arthritic Drugs
Title: - A descriptive study of anti arthritic Ayurvedic
products available in Pune region.
Dr. S. M. Sarpotdar submitted his dissertation to Pune
University in 2004 for the P.G. degree Msc (Health Science).
His guide was Dr. Bhushan Patwardhan (Msc, PhD) and
research centre was school of health Sciences, University of
Pune, M.S. India.
This study is under the domain of Ayurvedic
Phamacoepidemiology.
The aim of the study was to find outcome of the following
questions.
1) Are the P&P (Patent & proprietary) ayurvedic medicines ,
indicated in arthrithis, following the guideline of ayurved
therapeutics ?
2) What is the rationale behind P&P ayurvedic formulation
indicated in arthritis ?
Objectives of the study were as follows1) To study the rationale behind the formulation.
2) To study the regulatory status of P&P arthrithric drugs.
3) To study economical aspects of formulations.
Methodology1) Literary review – literary review of Ayurvedic classics was
done. References were also collected from modern textbooks,
ayurvedic pharmacopeias, FDA drug and cosmetic act 1940,
WHO guidelines for traditional medicines.
Study design: - Descriptive study
The product list of anti arthritic drugs available in medical
stores in Pune & Pimpri-Chinchwad area was made for
screening of the products. Following points were considered
1) Packing type, 2) Total number of tablets, capsules packing,
3) Manufacturing date, 4) Expiry date, 5) Storage guidelines,
6) Indications, 7) Contraindications, 8) Anupan (Vehicle) &
9) Cost per capsule or tablet.
Observations of the study are as follows:
Out of thirty-one products
a) The expiry date was mentioned on only sixteen products.
b) Only five products have a mention of storage guidelines.
c) Only two products have a mention of specific
contraindication such as pregnancy and lactation.
d) Only six products were purely herbal in origin however
twenty five were herbomineral products.
e) The most frequently utilized drugs were Ashwagandha
(Withania somnifera) and Sunthi (Gingiber officinale).
These drugs were utilized in 14 formulations.
f) Twenty formulations were manufactured in Maharastra
State and out of the remaining eleven products were
manufactured in the State of Gujarat and Karnataka
each. In Andhra Pradesh and Madhya Pradesh two
products were manufactured each. One product was
manufactured in Kerala.
The following Conclusions are drawn from the observations:
1) As per study, Ayurvedic patent and proprietary medicines
indicated in arthritis have not displayed the essential
information on their labels.
2) Most of the ayurvedic P&P medicines are following the
selection criteria of Ayurvedic therapeutics. However, the
principles of combination of Ayurveda are not followed.
Therefore, these combinations cannot be called as rational
combinations in the vision of Ayurveda.
3) The estimated monthly expenditure for the drug therapy of
classical Ayurvedic formulations, P&P formulations and first
generation NSAIDs is the same range i.e. 100 to 500 rupees.
Recommendations:
1) There is a need to modify regulatory guidelines for Ayurvedic
Medicines. New guidelines are essential which incorporate
the principles of Ayurvedic therapeutics and guidelines given
by above-mentioned International Agencies to improve the
status of Ayurvedic products in Global Medicinal Market.
2) License should be made compulsory for the sale of Ayurvedic
Drugs. In A current situations license is not essential for the
sale of Ayurvedic products.
3) As per ISM & H policy for P & P Ayurvedic products,
preclinical data on quality control, safety and efficacy should
be mandatory before launching the product in the market.
4) Modern scientific technology, Evidence based Modern
Medicine and traditional knowledge should be incorporated.
This golden triangle should apply for the exploration of
Ayurvedic drug discovery.
Data entry on 07/2/11
Given by Dr. RRD
Edited on: 25-2-11
Edited By Dr. RRD