S. mutans

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Present –
December 2004
January 2003
1996-
December 1996September 1989
Principal investigator in Microbial Communication Research Group
of Helmholtz Center for Infection Research. Head of laboratory.
Safety officer for pathogenic and gene manipulated microorganisms.
Cosupervisor of PhD thesis.
 Interaction and crossfeeding between C. albicans and S. mutans
 Interaction in polymicrobial biofilms of oral microorganisms.
 Transcriptome analysis by microarray approach.
 Analysis of S. sobrinus genome.
 Characterization of mleR, a positive regulator of malolactic
fermentation and part of the acid tolerance response in S. mutans.
 Role of delta subunit of RNA polymerase on virulence and
environmental adaptation of S. mutans.
 Fatty acid s signaling molecules influence on C. albicans hyphal
formation.
 Analysis of AI-2 mediated gene expression in S. mutans.
 Identification, quantification, and determination of the absolute
configuration of the bacterial quorum-sensing signal autoinducer-2
by gas chromatography-mass spectrometry.
 Analyzing traces of autoinducer-2 requires standardization of the
Vibrio harveyi bioassay.
Principal investigator in Biological Chemistry Group of Helmholtz
Center for Infection Research (before German National Institute for
Biotechnology GBF). Head of laboratory. Safety officer for
radioactive laboratory. Cosupervisor of PhD thesis.
 Genetic variations of gpx-4 and male infertility in humans
 Thiol-dependent peroxidases care little about homology-based
assignments of function
 Tryparedoxin peroxidase of Leishmania donovani: molecular
cloning, heterologous expression, specificity, and catalytic
mechanism.
 The putative glutathione peroxidase gene of Plasmodium falciparum
codes for a thioredoxin peroxidase.
 VEGF/Flk-1 interaction, a requirement for malignant ascites
recurrence.
 ATP-sensitive association of mortalin with the IL-1 receptor type I.
 Differential binding characteristics and cellular inhibition by soluble
VEGF receptors 1 and 2.
Principal Investigator in Enzyme Technology Division of German
National Institute for Biotechnology (GBF). Head of laboratory.
Safety officer for radioactive laboratory
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
Isolation, characterization and crystallization of many microbial
enzyme
Heterologous expression of many microbial enzymes.
August 1989 July
1973
Assistant Professor at Technical University of Wroclaw (Poland).
Biotechnology Division
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Microbial Lipases
Degradation of Toluen by P. putida
Microbial analysis of eutrophic lake
Educational experience at the University (Lecture, Practices)
.
Education
1973
1980
2000
University of Wroclaw (Poland)
Master of Science in Biology with emphasis on microbiology
Technical University of Wroclaw Poland
PhD in Biotechnology and Technics
TOEFL (Diploma of English as a Foreign Language).
Various courses for Computers and molecular biology technics
Licences
Coauthor of license for production of antibody against Flt1
Fellowship and Conferences
1985- Fellowship of Royal Society at Cranfield Institute of Technology (CIT).
Great Britain
1987 – Fellowship of British Council at Cranfield Institute of Technology (CIT).
Great Britain
AWARDS
Awards of National Academy of Science USA for lecture about quorum sensing in
S. mutans.
Many awards of President of Technical University
Many awards of Director of Helmholtz Institute for Infection Research (HZI) and
German National Institute for Biotechnology (GBF).
Skills
MS Word, MS Excel, Power point and Adobe Photoshop, Adobe Ilustrator. Working on
various scientific Databases.
Driving license
Languages
German –Fluent
English – Fluent
Polish – Fluent
Russian – Intermediate
Professional Skills
Teamwork
Communication
Sense of organization
Ability of fast learning
Personal Interests
Mountain trekking
Biking
Classical music, reading
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