Johan Bourghardt Fagman CV
Curriculum Vitae
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Johan Bourghardt Fagman
Swedish
Wallenberg Laboratory for Cardiovascular Research
Sahlgrenska University Hospital/Sahlgrenska
Bruna Stråket 16, SE-413 45 Gothenburg, Sweden
+46 706 238876
johan.bourghardt@wlab.gu.se
Current Research Position
Postdoctoral Researcher
Wallenberg Laboratory, University of Gothenburg, Sweden
November 2010 - Present
Working on my unpublished PhD-project Atherosclerosis in Female Mice Lacking the Androgen
Receptor.
Education
Ph.D. in Medicine - Endocrinology
November 19, 2010
Institute of Medicine, the Sahlgrenska Academy, University of Gothenburg, Sweden
Thesis Title: Actions of androgens and estrogens in experimental models of cardiovascular disease
Supervisor: Åsa Tivesten, M.D., Ph.D.
Co-supervisor: Alexandra Krettek, Ph.D.
M.S. in Pharmaceutical Bioscience
January 26, 2005
Wallenberg Laboratory, University of Gothenburg, Sweden
Thesis Title: Immune Modulation and Body Fat
Supervisor: John-Olov Jansson, M.D., Ph.D.
Peer-reviewed Publications
 Bourghardt J, Wilhelmson AS, Alexanderson C, De Gendt K, Verhoeven G, Krettek A, Ohlsson
C, Tivesten A. Androgen receptor-dependent and independent atheroprotection by testosterone in
male mice. Endocrinology. 2010 Nov;151(11):5428-37.
 Bourghardt J, Bergström G, Krettek A, Sjöberg S, Borén J, Tivesten A. The endogenous estradiol
metabolite 2-methoxyestradiol reduces atherosclerotic lesion formation in female apolipoprotein
E-deficient mice. Endocrinology. 2007 Sep;148(9):4128-32.
Manuscripts
 Bourghardt Fagman J, Wilhelmson AS, Alexanderson C, De Gendt K, Verhoeven G, Holmäng
A, Olofsson SO, Krettek A, Ohlsson C, Tivesten A. Increased atherosclerosis and metabolic
dysfunction in female androgen receptor-deficient mice. Manuscript in preparation
 Bourghardt Fagman J*, Alexanderson C*, Wilhelmson AS, De Gendt K, Verhoeven G, Tivesten
A. Protection against the development of abdominal aortic aneurysms in male androgen receptor
deficient mice. Manuscript in preparation (* equal contribution)
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Johan Bourghardt Fagman CV
 Wilhelmson AS, Bourghardt Fagman J, Fogelstrand P, Gogos JA, Tivesten A. Catechol-Omethyltransferase (COMT) is dispensable for vascular protection by estradiol in vivo. Manuscript
in preparation
Conference Abstracts
 Bourghardt J, Wilhelmson AS, Alexanderson C, De Gendt K, Verhoeven G, Holmäng A, Krettek
A, Ohlsson C, Tivesten A. Accelerated atherosclerosis associated with hypertriglyceridemia,
insulin resistance and obesity in female mice lacking the androgen receptor. Poster presented at the
92nd Annual Meeting of the Endocrine Society. San Diego, CA, USA, June 19-22, 2010.
 Bourghardt J, Wilhelmson AS, De Gendt K, Verhoeven G, Krettek A, Ohlsson C, Tivesten A.
The androgen receptor is involved in gonadal atheroprotection in both male and female mice.
Poster presented at the 15th International Symposium on Atherosclerosis. Boston, MA, USA, June
14-18, 2009.
 Bourghardt J, Wilhelmson AS, De Gendt K, Verhoeven G, Krettek A, Ohlsson C, Tivesten A.
The androgen receptor is involved in gonadal atheroprotection in both male and female mice. Talk
given at the 15th Annual Scandinavian Atherosclerosis Conference. Humlebaek, Denmark, April
22-25, 2009.
 Bourghardt J, Mattsson-Hultén L, Sjoberg S, Krettek A, Tivesten A. Possible mechanisms for the
anti-atherogenic effect of the estradiol metabolite 2-methoxyestradiol. Poster presented at the 14th
Annual Scandinavian Atherosclerosis Conference. Humlebaek, Denmark, June 11-14, 2008.
Other Publications
 Bourghardt J, Actions of androgens and estrogens in experimental models of cardiovascular
disease, Doctoral Thesis, University of Gothenburg, October 31, 2010.
(http://hdl.handle.net/2077/22923)
Awards
 Student Travel Grant, the Sahlgrenska Academy Funds, University of Gothenburg, Sweden
The 92nd Annual Meeting of the Endocrine Society (ENDO 2010), June 19-22, 2010.
 Student Travel Grant, the Sahlgrenska Academy Funds, University of Gothenburg, Sweden
The 15th International Symposium on Atherosclerosis (ISA 2009), June 14-18, 2009.
Society Memberships
 Student Member of the Endocrine Society 2010
 Member of the International Atherosclerosis Society (IAS) 2008-Present
 Member of the Scandinavian Society for Atherosclerosis Research (SSAR) 2008-Present
03/17/11
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