Analysis of Polar Molecules
Chromatographic Society Spring Symposium & AGM
Wednesday and Thursday 21st-22nd May 2014,
AstraZeneca, Macclesfield, UK
At this meeting, the latest approaches towards the analysis of polar and other pharmaceutically relevant
molecules will be reviewed. It will be of interest to all practitioners of separation science, particularly
those using chromatography for problem solving in the analytical and bio-pharmaceutical fields. Analytical
approaches to be presented in the meeting will include SFC, Capillary Electrophoresis, HILIC (and other
LC approaches) for both small-molecule and oligonucleotide pharmaceuticals.
There will also be a suppliers (both instrument and consumables) exhibition during the meeting alongside
vendor presentations in the programme, where our principal sponsor for this meeting is Shimadzu.
The venue is the UK R&D centre for one of the world’s largest pharmaceutical companies – AstraZeneca
which has a rich history of developing and manufacturing a number of important products including
Zoladex, Faslodex, Caprelsa and Zomig amongst many others.
The theme for this meeting is ‘Analysis of Polar Molecules’. We have a number of confirmed speakers from
academia and industry including Prof. Wolfgang Lindner (University of Vienna, Austria), Prof. Apryll
Stalcup (Dublin City University, NI), Tim Underwood (GSK), Dr Mark Taylor (Pfizer) and Dr James
Heaton (University of the West of England), Dr George Okafo (GSK) and Dr Caroline West (University of
Orleans, France) alongside vendor presentations from Shimadzu, Agilent, Thermo Fisher Scientific and
Waters (to date).
We hope you can join us for this interesting and topical meeting.
Chromatographic Society Spring meeting and AGM
21tst-22nd May 2014, AstraZeneca, Macclesfield, UK
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Chromatographic Society Spring Symposium & AGM
21st-22nd May 2014, AstraZeneca, Macclesfield, UK
Note: Speakers, topic areas or presentation times may be subject to change
Day 1
12:00
Registration and light buffet lunch
13:00
Welcome address – Paul Ferguson (AstraZeneca, Vice-President of the Chromatographic
Society) & Alan Handley (LGC, President of the Chromatographic Society)
Session 1: Current state-of –the art: Keynote Speakers
13:15
Professor Apryll Stalcup (Dublin City University, Ireland) – Title TBC
14:00
Professor Wolfgang Lindner (University of Vienna, Austria) - Enantioseparation of
highly polar and ampholytic compounds: A challenge to be mastered
Gold Sponsor Presentation
14:40
Speaker TBC (Shimadzu) - Solutions for Normal Phase Screening
15:10
Tea Break
Scientific Vendor Presentations
15:30
Speaker TBC (Agilent) – Title TBC
15:50
Professor Tony Edge (Thermo Fisher Scientific) – The use of mixed mode ion exchange
columns for the retention and separation of polar molecules
16:10
Rob Frost (Waters) - New Approaches for Successful Polar Compound
Retention
16:30
Tea Break
Session 2: Invited lectures: Supercritical Fluid Chromatographic approaches
16:45
Dr Caroline West (University of Orleans, France) - Where are the polarity limits for SFC?
17:10
Jenny Kingston (Novartis) - SFC as an adaptable separation technology improving the elution and peak shape of polar molecules by customising
mobile and stationary phase conditions
Chromatographic Society Spring meeting and AGM
21tst-22nd May 2014, AstraZeneca, Macclesfield, UK
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17:35
Dr Andy Poulton (AstraZeneca) – Adventures with SFC for high throughput asymmetric
screens
17:50
Panel discussion on SFC
18:00
Close of Day 1 and evening arrangements
19.30
Symposium Dinner (Shrigley Hall, Pott Shrigley. Transport provided from designated hotels –
see ‘Accommodation’ below)
Day 2
9:00
Arrival and coffee
Session 3: Liquid Chromatographic approaches
9:30
Dr Mark Taylor (Pfizer) - Gaining New insights into Pharmaceutical Stability
using Electrochemical Reaction Cells
10:00
Dr James Heaton (University of the West of England) - Investigation into the
efficiency and optimal operating conditions of hydrophilic interaction
compared with reversed-phase liquid chromatography
10:30
Tim Underwood (GSK) - Generic Approaches to the Analysis and Purification
of Small, Highly Polar Molecules
11:00
Tea Break
Scientific Vendor Presentations 2
11:40
TBC
12:00
TBC
12:20
TBC
12:40
Lunch
13:10
AGM
Session 4: Oligionucleotides and related molecules
14:00
Dr George Okafo (GSK) – Development Strategies for Impurity Profiling: An Industry
Case Study for Synthetic Oligonucleotides
14:30
Dr Cari Sänger – van de Griend (Kantisto, The Netherlands) - Polarization of
the use of the CE techniques in pharma industry?
15:00
Laurent Joron (Dow Chemical, France) - Chromatographic separation of Peptides and
Oligonucleotides with Polymeric Reverse Phase Materials
15.30
Dr Elena Bichenkova (University of Manchester) - Analysis of oligonucleotides and
their synthetic analogues using HPLC-NMR hyphenated analytical techniques
16:00
Closing Address: Alan Handley or Paul Ferguson
Chromatographic Society Spring meeting and AGM
21tst-22nd May 2014, AstraZeneca, Macclesfield, UK
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Directions to the meeting
Chromatographic Society Spring meeting and AGM
21tst-22nd May 2014, AstraZeneca, Macclesfield, UK
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Accommodation
Accommodation for the meeting is available at nearby hotels. Delegates should contact the hotel directly to
make a booking.
Hotels listed by distance from AZ Macclesfield site (Silk Road Business Park, Macclesfield, SK10 2NA).
Note other accommodation is available in the local area.
Moorhayes House
27 Manchester Road, Tytherington, Macclesfield,
SK10 2JJ
Tel: 01625 433228
Email: helen@moorhayes.co.uk
www.moorhayes.co.uk/
Distance to AZ Macclesfield site by car (Google
maps): 1.0 miles
Travelodge Macclesfield Central
Venue on Symposium Dinner bus collection route
Castle House, Gas Road, Macclesfield, SK11 6JS
Tel: 01625 612117
www.travelodge.co.uk/hotels/412/MacclesfieldCentral-hotel
Distance to AZ Macclesfield site by car (Google
maps): 1.5 miles
Premier Inn Macclesfield North
Springwood Way, Macclesfield SK10 2XA
Tel: 0871 527 8694
www.premierinn.com
Distance to AZ Macclesfield site by car (Google
maps): 1.7 miles
Venue on Symposium Dinner bus collection route
Chromatographic Society Spring meeting and AGM
21tst-22nd May 2014, AstraZeneca, Macclesfield, UK
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The Bridge Hotel
New Rd, Prestbury, Macclesfield, Cheshire SK10
4DQ
Tel: 01625 829326
Email: reception@bridge-hotel.co.uk
www.bridge-hotel.co.uk
Distance to AZ Macclesfield site by car (Google
maps): 3.0 miles
Venue on Symposium Dinner bus collection route
Hollin Hall Hotel
Jackson Lane, Kerridge, Macclesfield, SK10 5BG
Tel: 01625 573246
Email: Reservations@hollinhallhotel.com
www.hollinhallhotel.com
Distance to AZ Macclesfield site by car (Google
maps): 3.1 miles
Travelodge Macclesfield Adlington Hotel
A523 London Road, South Adlington, Macclesfield,
Cheshire, SK10 4NG
Tel: 0871 9846158
http://www.travelodge.co.uk/hotels/152/Macclesfield
-Adlington-hotel
Distance to AZ Macclesfield site by car (Google
maps): 4.7 miles
De Vere Hotel Mottram Hall
Wilmslow Rd, Mottram St Andrew, Macclesfield,
SK10 4QT
Telephone: 0871 222 4686*
Email: dmh.sales@devere-hotels.com
www.devere-hotels.co.uk/hotellodges/locations/mottram-hall.html
Distance to AZ Macclesfield site by car (Google
maps): 5.3 miles
Chromatographic Society Spring meeting and AGM
21tst-22nd May 2014, AstraZeneca, Macclesfield, UK
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Registration Information
Chromatographic Society Spring Symposium & AGM
Wednesday and Thursday 21st-22nd May 2013,
AstraZeneca, Macclesfield, UK
Analysis of Polar Molecules
The symposium will be held over two days, starting at lunchtime on Wednesday 21st May at AstraZeneca, Silk
Road Business Park, Macclesfield, UK and finishing on Thursday 22nd May 2014.
The symposium dinner will be held on the evening of the 21st May and will be at a local country hotel. Dinner places
will be sold on a first come first served basis. Please choose the appropriate fee at the point of registration if
you would like to attend the dinner.
Site Security will require Photo I.D – all attendees will be required to provide a scanned copy of their passport,
driving license or similar in advance of the meeting. This should be emailed to the following address
chromsoc@meetingmakers.co.uk
Failure to provide I.D in advance of the meeting may result in delegates not being able to participate on-site.
The same form of original I.D must also be carried with you on-site at the meeting.
The following costs cover, full registration, attendance at all sessions, lunches and access to the exhibition;
Members of Chromatographic Society, BMSS, RSC C&E Group, SCI and EuSSS
£160 (incl. VAT)
Members of Chromatographic Society, BMSS, RSC C&E Group, SCI and EuSSS
£200 (incl. VAT and Symposium dinner)
Non Members
£260 (incl. VAT)
Non Members
£300 (incl. VAT and Symposium dinner)
Students and Retired Persons
£60 (incl. VAT)
A limited number of student and non-waged bursaries are available; please contact Meeting Makers
chromsoc@meetingmakers.co.uk for further details.
We are accepting both electronic and postal registrations as follows;
-Electronic; please register on-line by visiting our website http://www.chromsoc.com/ChromsocEvents.aspx
-Postal; please request a registration form from the Chromatographic Society - chromsoc@meetingmakers.co.uk
Chromatographic Society Spring meeting and AGM
21tst-22nd May 2014, AstraZeneca, Macclesfield, UK
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