Internally Funded PhD Projects in the Centre for Research in
Biosciences (CRIB) at the
University of the West of England (UWE), Bristol, UK
(2015)
The Centre for Research in Biosciences (CRIB) at UWE, Bristol hosts world class multidisciplinary,
collaborative research in Biomedicine; Bio-sensing Technology; and Agri-Food, Plant and Environmental
Sciences. We have a range of potential PhD projects available; see our webpages at:
http://www1.uwe.ac.uk/hls/research/biosciences.aspx
CRIB addresses both fundamental and applied aspects of research. Numerous links with national and
international partners in universities, research institutes and commercial organisations ensure that CRIB
research has real social and economic impact. Our extensive and modern research facilities offer
excellent methodological training opportunities for our PhD students. Working with the University
Graduate School, we also provide our research students with a comprehensive skills development
package in Research and Project Development; Personal Development and Transferable Skills; and
Knowledge Exchange, Industry and End-Users Engagement, Science Communication and Public
Engagement. Most of our PhD graduates are employed within one year of PhD completion in various
sectors including universities, research institutes, industry and scientific publishing.
Further information about the project areas, supervisors and relevant publications can be found via the
links provided. Please contact the relevant supervisors for further information.
1. Hydrophilic interaction chromatography and its application to the determination of antibiotics.
Professor David McCalley (David.Mccalley@uwe.ac.uk) (Project ref no. DTA01)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\dv-mccalley
2. The biological role for bioluminescence in bioluminescent bacterial biosensor systems.
Dr Gareth Robinson (Gareth.robinson@uwe.ac.uk) (Project ref no. DTA02)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\g2-robinson
3. Effects of dietary factors on the alternative splicing of genes linked to prostate cancer.
Dr Michael Ladomery (Michael.ladomery@uwe.ac.uk) (Project ref no. DTA03)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\m-ladomery
4. The role of pancreatic islet cell glutamate receptors in endocrine hormone secretion and in the
development of diabetes.
Professor Aniko Varadi (Aniko.varadi@uwe.ac.uk )
(Project ref no. DTA04)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\a-varadi
5. Disposable acetone breath sensors for non-invasive management of diabetes
Professor Tony Killard (Tony.killard@uwe.ac.uk)
(Project ref no. DTA05)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\a-killard
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6. A new generation of diagnostics using NanoCOPS
Professor Tony Killard (Tony.killard@uwe.ac.uk)
(Project ref no. DTA06)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\a-killard
7. Global coagulation monitoring using sensors to mimic the vascular
endothelium.
Professor Tony Killard (Tony.killard@uwe.ac.uk)
(Project ref no. CRIB01)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\a-killard
8. Miniaturised fuel cell sensors.
Professor Tony Killard (Tony.killard@uwe.ac.uk) (Project ref no. DTA07)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\a-killard
9. Developing miniaturised electrochemical biosensors for monitoring mammalian cell
metabolism in vitro.
Dr Roy Pemberton (Roy.pemberton@uwe.ac.uk) (Project ref no. CRIB02)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\rm-pemberton
10. Lysophosphatidate tethered teicoplanin - a dual action biomaterial surface
finish for bone regenerative applications
Dr Jason Mansell (Jason.mansell@uwe.ac.uk) (Project ref no. DTA08)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\jp-mansell
11. Development of a rapid and cost effective ‘on-site’ detection method for Cacao Swollen
Shoot Virus (CSSV)
Dr Joel Allainguillaume (Joel.allainguillaume@uwe.ac.uk) (Project ref no. CRIB04)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\j-allainguilla
12. Biomarkers and therapeutic targets for solid tumours.
Professor Myra Conway (Myra.conway@uwe.ac.uk) (Project ref no. DTA09)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\d-qualtrough
13. Healthy Trees: understanding the factors that control pathogenicity and virulence of tree
pathogens
Professor Dawn Arnold (Dawn.arnold@uwe.ac.uk) (Project ref no.CRIB05)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\dl-arnold
14. Innovative use of eDNA technologies by developing countries for the conservation of coral
reef fish communities
Dr Lyn Newton (Lyn.newton@uwe.ac.uk) (Project ref no. CRIB06)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\lc-newton
15. The function of glycine rich RNA-binding proteins (GRPs) in the ABA-mediated responses of
Arabidopsis thaliana
Dr Ian Wilson (Ian2.wilson@uwe.ac.uk) (Project ref no. CRIB07)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\id-wilson
16. The role of protein trafficking in bone lysis in Multiple Myeloma
Dr Ruth Morse (Ruth.morse@uwe.ac.uk ) (Project ref no. DTA10)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\hr-morse
17. Interaction between leukaemic cells and the bone marrow stroma
Dr Gareth Robinson (Gareth.robinson@uwe.ac.uk) (Project ref no. DTA11)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\g2-robinson
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18. Does the relationship between biodiversity and ecosystem function change
during conversion of tropical forest to oil palm plantation?
Dr Farnon Ellwood (Farnon.ellwood@uwe.ac.uk)
(Project ref no. CRIB08)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\mdf-ellwood
19. Immune protection against upper respiratory tract infections using commensal Lactobacilli
and Neisseriae
Dr Victoria Davenport (Victoria.davenport@uwe.ac.uk)
(Project ref no. DTA12)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\cv-davenport
20. Identifying organisms that cross-react with group A Neisseria meningitidis
Dr Victoria Davenport (Victoria.davenport@uwe.ac.uk) (Project ref no. DTA13)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\cv-davenport
21. The effect of environmental conditions on the expression of and activity of the betalactamase enzyme of the respiratory pathogen Moraxella catarrhalis
Dr Lynne Lawrance (Lynne.lawrance@uwe.ac.uk) (Project ref no. DTA14)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\lm-lawrance
22. The regulation of tumour invasion and metastasis in colorectal cancer: the influence of diet
and lifestyle on tumour progression
Dr David Qualtrough (David.qualtrough@uwe.ac.uk)
(Project ref no. DTA15)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\d-qualtrough
23. The regulation of tumour invasion and metastasis in breast cancer: the role of
developmental signalling pathways
Dr David Qualtrough (David.qualtrough@uwe.ac.uk)
(Project ref no. DTA16)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\d-qualtrough
24. EVE UK Peat -Examining the Variation of different types of Enzyme inhibition in UK
peatlands?
Professor Darren Reynolds (Darren.reynolds@uwe.ac.uk) (Project ref no. CRIB09)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\dm2-reynolds
25. Unravelling the phosphate paradox of pine forest Andisols
(Project ref no. CRIB10)
Associate Professor Neil Willey (Neil.willey@uwe.ac.uk)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\nj-willey
26. Investigation of potential drug targets for the treatment of urinary incontinence and
nocturia.
Dr Bahareh Vahabi (Bahareh.vahabi@uwe.ac.uk) (Project ref no. DTA17)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\b-vahabi
27. Developing eDNA survey techniques to monitor freshwater species populations
Dr Joel Allainguillaume (Joel.allainguillaume@uwe.ac.uk) (Project ref no. CRIB11)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\j-allainguilla
28. Elucidating host interactions between bacteriophages and multiple drug resistant Klebsiella
pneumoniae
Professor Darren Reynolds (Darren.reynolds@uwe.ac.uk) (Project ref no. DTA18)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\dm2-reynolds
29. The development of off-grid water treatment technologies for the recovery of agricultural
wastes.
Professor Darren Reynolds (Darren.reynolds@uwe.ac.uk) (Project ref no. CRIB12)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\dm2-reynolds
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30. Biofilms in wounds; using microbial metabolomics for the rapid diagnosis of wound
infection.
Professor Darren Reynolds (Darren.reynolds@uwe.ac.uk) (Project ref no. DTA19)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\dm2-reynolds
31. Chemotherapeutic disruption of microtubular assembly as an aetiology of peripheral
neuropathy and second primary malignancies
Dr Ruth Morse (Ruth.morse@uwe.ac.uk) (Project ref no. DTA20)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\hr-morse
32. Hydrogen sulfide: signaling and effects in biological systems
Dr John Hancock (John.hancock@uwe.ac.uk) (Project ref no. CRIB13)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\jt-hancock
33. Oxidative stress, nitric oxide and hydrogen sulfide signalling in plant stress responses
Dr John Hancock (John.hancock@uwe.ac.uk) (Project ref no. CRIB14)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\jt-hancock
34. Validation of a 3D bone marrow model for toxicity testing and stem cell transplantation
Dr Ruth Morse (Ruth.morse@uwe.ac.uk) (Project ref no. DTA21)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\hr-morse
35. Understanding the role of aggregation and protein misfolding in neurodegenerative
conditions such as Alzheimer’s disease
Professor Myra Conway (Myra.conway@uwe.ac.uk) (Project ref no. DTA22)
http://people.uwe.ac.uk/Pages/person.aspx?accountname=campus\me-conway
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