CURRICULUM VITAE
Yu-Ting Chou
周裕珽
Academia Sinica
Institute of Biomedical Sciences
128 Sec. 2, Academia Rd. Nankang,
Taipei 115, Taiwan, R.O.C
Phone: (02) 2789-9011
Fax: (02) 2652-3075
ytchou@ibms.sinica.edu.tw
Birthdate:
August
Birthplace:
Tainan, Taiwan
Citizenship:
Taiwan, R.O.C.
Education:
2000- 2006
1994-1996
1990-1994
Experience:
2008-present
23, 1972
Ph.D. Case Western Reserve University
Department of Pharmacology, Cleveland, USA
M. S. National Yang-Ming University
Institute of Microbiology and Immunology, Taipei, Taiwan
B. S. Chinese Culture University,
Department of Biology, Taipei, Taiwan
2007-2008
Postdoctoral fellow: Laboratory of Dr. Cheng-Wen Wu
Academia Sinica, Institute of Biomedical Sciences, Taipei,
Taiwan
Postdoctoral fellow: Laboratory of Dr. Cheng-Wen Wu
National Health Research Institutes, National Institute of
Cancer Research, Miaoli, Taiwan; Academia Sinica,
Institute of Biomedical Sciences, Taipei, Taiwan
2006-2007
Postdoctoral fellow
Johns Hopkins Medical Institutions,
Department of Orthopaedic Surgery and Oncology
Research Assistant
National Taiwan University, Department of Agricultural
Chemistry.
Second lieutenant, Medical Service Officer
Compulsory Military Service, Jiayi, Taiwan
1999-2000
1996-1998
Research Interests:

Cancer Stem Cell

Cancer Plasticity and DNA Methylation

Cytokine and hypoxia Mediated Cancer Progression

Therapeutic Applications of Stemness and Oncogenic Targets
Publications:
Articles
1. Chou YT, Lin HH, Lien YC, Wang YH, Hong CF, Kao YR, Lin SC, Chang
YC, Lin SY, Chen SJ, Chen HC, Yeh SD, and Wu CW. EGFR promotes
lung tumorigenesis by activating miR-7 through a Ras/ERK/Myc pathway
that targets the Ets2 transcriptional repressor ERF. Cancer Res. 2010 Nov
1;70(21):8822-31.
2. Chiou SH*, Wang ML*, Chou YT*, Chen CJ, Hong CF, Hsieh WJ, Chang
HT, Chen YS, Lin TW, Hsu HS, Wu CW. Coexpression of Oct4 and Nanog
enhance malignancy in lung adenocarcinoma by inducing cancer stem
cell-Like
properties
and
epithelial-mesenchymal
transdifferentiation.
Cancer Res. 2010 Dec 15;70(24):10433-442010 (* equally contributed as
the first author).
3. Chou YT, Hsieh CH, Hsu CF, Kao YR, Lee CC, Pang ST, Shieh YS, Chiou
SH, Wu CW. CITED2, a molecular switch of cytokine-induced proliferation
and quiescence (EMBO J, 2011, in revision)
4. Lau WM, Weber KL, Doucet M, Chou YT, Brady K, Kowalski J, Tsai HL,
Yang J, Kominsky SL. Identification of prospective factors promoting
osteotropism in breast cancer: a potential role for CITED2. Int J Cancer.
2010, Feb 15;126 (4):876-84.
5. Hong CF, Chou YT, Lin YS, Wu CW. MAD2B, a novel TCF4-binding
protein,
modulates
TCF4-mediated
epithelial-mesenchymal
transdifferentiation. J Biol Chem. 2009, Jul 17; 284 (29):19613-22.
6. Qu X, Doughman YQ, Chen Y, Chou YT, Lam E, Turakhia M, Dunwoodie
SL, Watanabe M, Xu B, Duncan SA, Yang YC. Cited2, a coactivator of
HNF4alpha, is essential for liver development. EMBO J. 2007,
26(21):4445-56.
7. Chou YT and Yang YC. Posttranscriptional Control of Cited2 by TGFregulation via Smads and Cited2 coding region J Biol Chem. 2006, 281
(27): 18451-62.
8. Chou YT, Wang H, Danielpour D, Chen Y and Yang YC. Cited2 modulates
TGF-
-mediated upregulation of MMP9. Oncogene 2006, 25 (40):
5547-60.
9. Chou YT. Cited2, an autoregulated transcriptional modulator, in TGFsignaling. CWRU Dissertation 2006,
10. Chou YT, Lee CC, Lin SC, Kao YR, Chen CT, Wei YH and Wu CW. Sox2,
an oncogenic stemness factor regulating cell proliferation and autophagic
cell death of lung cancer (2011, submission).
Abstracts
1. Chou YT, Lee CC, Lin SC, Wu CW. A Sox2-EGFR Positive Feedback Loop
Contributes to Oncogenesis of Lung Cancer. American Association for Cancer
Research (AACR) Annual Meeting 2011, Orlando, FL, USA
2. Chou YT, Hsu CF, Kao YR, and Wu CW. Cited2, a novel EGFR-induced
coactivator, plays a key role in lung cancer progression. American Association
for Cancer Research (AACR) Annual Meeting 2010, Washington, DC, USA
3. Chou YT*, Lin HH, Wu CW. mir-7, an EGFR induced microRNA, modulates
lung cancer progression (*Selected oral presentation in mini-symposium).
American Association for Cancer Research (AACR) 100th Annual Meeting
2009, Denver, Colorado, USA
4. Chou YT, Chen CJ, Chiou SH, Hsieh WJ, Wang ML, Wu CW. Role of
embryonic stem cell signaling in cancer progression. International Society for
Stem Cell Research (ISSCR) 7th Annual Meeting 2009, Barcelona, Spain
5. Chou YT and Yang YC. Cited2 is a transcriptional modulator in TGFsignaling pathway. American Society of Hematology (ASH) Meeting 2003, San
Diego, CA
Honors:
1. Academia Sinica Distinguished Postdoctoral
Scholarship 2008-2010
2. Microbiology and Immunology Scholarship 1996
3. Natural Science Scholarship 1990-1994
Members:
1. American Association for Cancer Research
2. American Society of Hematology
3. The Phi Tau Phi Scholastic Honor Society
Committee:
Biomedical Graduate Student Symposium, 2002,
Case Western Reserve University