PEER REVIEWED ORTHOPAEDIC RESEARCH PROGRAM (PRORP)
PRORP is a research program within the Congressionally Directed Medical Research Program of the Department of
Defense.
A. History
Understanding how to treat and facilitate rapid recovery from orthopaedic injuries is a priority within the military
health system. A majority of the injuries sustained by military personnel in U.S. war efforts involve soft tissue
wounds and bone fractures, pointing to a need for orthopaedic research that will provide superior medical care and
treatment options. Frequent outcomes and complications in amputated or salvaged limbs include infection,
compartment syndrome, non-union, heterotopic ossification, and temporary or permanent muscle function loss,
among others. The PRORP crafts investment strategies and funding portfolios to address these challenges, with
the goal of helping injured service members achieve optimal recovery from combat-related orthopaedic injuries.
The DOD PRORP was established by Congress in FY09 with appropriations totaling $112 million to support
military-relevant, peer-reviewed orthopaedic research. The program was continued in FY10 with a congressional
appropriation of $22.5 million. The appropriation for FY11 is $24 million. (Source: CDMRP/PRORP brochure)
B. PRORP Vision
Provide all Warriors affected by orthopaedic injuries sustained in the defense of our Constitution the opportunity
for optimal recovery and restoration of function.
C. PRORP Mission
Address the leading burden of injury and loss of fitness for military duty by funding innovative, high-impact,
clinically relevant research to advance optimal treatment and rehabilitation from musculoskeletal injuries
sustained during combat or combat-related activities.
D. Contact information
1. Program Manager (may be contacted to discuss the scientific “fit” of a project for the PRORP funding
opportunities): Dr. Allison Milutinovich, 301-619-7099.
2. Making contacts regarding proposals: Before submitting a pre-application, the Program Manager may be
contacted about the appropriateness of the project for the funding opportunity.
3. During the application process: Inquiries on application preparation, application format, or required
documentation may be addressed by phone, fax, or e-mail as detailed in the Foreword of each Program
Announcement. Guidance on matters related to scientific issues will not be provided.
E. Requests for Information
Occasionally, PRORP will request input from scientists and potential PIs regarding program announcements that
are being considered, in order to determine interest and appropriate technologies to carry out the potential
research projects. These opportunities are announced on the PRORP website
http://cdmrp.army.mil/prorp/default.shtml.
F. FY11 Peer Reviewed Orthopaedic Research Program (PRORP) funding opportunities:
Mechanism
Clinical Trial Award
Funding Opportunity
Number: W81XWH11-PRORP-CTA
Release
Date
July 9,
2011
Funding Amount



Technology
Development Award
Funding Opportunity
Number: W81XWH11-PRORP-TDA
July 9,
2011


Submission Deadline
Maximum funding of $2.5M for
direct costs (plus indirect costs)
Period of performance not to
exceed 4 years
With Nested Career
Development Option: Maximum
funding of $2.725M for direct
costs (plus indirect costs)
Pre-Application (Preproposal):
September 7, 2011
Invitation to Submit an
Application: By October 4, 2011
Application: December 5, 2011
Maximum direct costs of $2M
(plus indirect costs)
Period of performance up to 4
years
Pre-Application (Preproposal):
September 7, 2011
Invitation to Submit an
Application: By October 4, 2011
Application: December 5, 2011
August 15, 2011
Translational
Research
Partnership Award
Funding Opportunity
Number: W81XWH11-PRORP-TRPA
July 9,
2011


Period of performance up to 4
years
Period of performance up to 3
years
Pre-Application (Preproposal):
September 7, 2011
Invitation to Submit an
Application: By October 4, 2011
Application: December 5, 2011
Full text of the Program Announcements can be found at the Grants.gov website
http://www07.grants.gov/search/basic.do by entering the Funding Opportunity Numbers listed in column one of the
table, above.
G. Application Summary/Success Rate in PRORP. FY09: 357 applications received, 95 applications funded
H. FY10 Peer Reviewed Orthopaedic Research Program Peer Reviewers
Adams, Christopher Ph.D. Department of Anatomy, Philadelphia College of Osteopathic Medicine
Adams, Zaneta Wounded Warrior Project
Calhoun, Jason M.D. Department of Orthopaedics, Ohio State University
Gibson, William Jr. United States Marine Corps
McHale, Kathleen M.D., FACS Clinical Professor of Orthopaedic Surgery, George Washington University
Olmsted-Davis, Elizabeth Ph.D. Pediatric Hematology-Oncology, Baylor College of Medicine
Pomeranz, Bruce M.D. Chester and Saddle Brook Campuses, Kessler Institute for Rehabilitation
Rosier, Randy M.D., Ph.D. Department of Orthopaedics, University of Rochester
Sachs, Jody DPM, Division for Clinical Research Resources, NIH/National Center for Research Resources
Soriano, Rachna D.O. Physical Medicine and Rehabilitation, Rehabilitation Institute of Chicago
Taylor, Kenneth M.D. Department of Surgery, Tripler Army Medical Center
I. PRORP’s Integration Panel or IP, composed of renowned experts – scientists and clinicians, as well as disease
survivors, reviews programmatic priorities on a yearly basis. These priorities are areas that will move the field of
research forward and may include gaps in knowledge of a disease, unfunded or underfunded approaches to
preventing, diagnosing, treating, or curing the disease, or resources needed to conduct research. The IP advises the
CDMRP staff on devising appropriate Program Announcements.
FY11 Integration Panel
Brig.Gen. Michael Yaszemski, MD, PhD (Chair)
Mayo Clinic
Kelley Brix, PhD
Office of the Secretary of Defense, Health Affairs
COL Rachel Evans, PhD
Center for the Intrepid, Brooke Army Medical Ctr
COL James Ficke, MD
Brooke Army Medical Center
COL Dallas Hack, MD
USAMRMC Combat Casualty Care Research Area
Directorate
COL Janet Harris, PhD
USAMRMC Clinical and Rehabilitative Medicine
Research Area Directorate
Robert Jaeger, PhD
Department of Veterans Affairs
Lt. Col. Warren Kadrmas, MD
Wilford Hall Medical Center
Adam Kisielewski
Operation Second Chance
Jonathan Kuniholm
Open Prosthetics Projects
Jon Mogford, PhD
Defense Advanced Research Projects Agency
CAPT James Panagis, MD
National Institute of Arthritis and Musculoskeletal
and Skin Diseases
COL Paul Pasquina, MD
Walter Reed Army Medical Center
COL Billie Jane Randolph (Ret), PhD
Department of Veterans Affairs
Jose Ramos
Disabled Sports USA
CDR Michael Rosenthal, DSc
Naval Medical Center San Diego
Marc Swiontkowski, MD
University of Minnesota
CAPT Daniel Unger, MD
Naval Medical Center Portsmouth
August 15, 2011