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Research Scientists for Cell Engineering Group
Oxford, Oxfordshire
Salary competitive
Two positions: 1 Permanent position & 1 Maternity Cover
Profile of Role
Oxford BioMedica’s Cell Engineering Group is being expanded to support an increasing company
portfolio of cell and gene therapies. The team is involved in the development, optimisation and
characterisation of lentiviral vectors. In addition, the team is responsible for the development of
stable lentiviral vector packaging and producer cell lines.
Highly motivated and independent individuals are sought to work within this team. The successful
candidates will be involved in:
─ the planning and performing of non-clinical grade large scale viral vector preparations
─ the development and optimisation of lentiviral vector production
─ the characterisation of lentiviral vector for advancement to preclinical studies
─ the development of stable lentiviral vector producer cell lines and the screening of resulting
producer clones
─ Any other activities within the Research Group
Skills/Knowledge/Qualifications
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BSc or PhD in a relevant Bioscience that is relevant to the work carried out in the Research
Group at Oxford BioMedica
Knowledge in Virology would be an advantage
Lab technical experience with particular emphasis on Tissue Culture, qPCR and Molecular
Biology
Good level of communication and presentation skills
Ability to work well in a team
Key Tasks
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Development and optimisation of new lentiviral vector products
Cell line engineering for the development of new cell lines for the production of lentiviral
vector products
Process development to optimise and improve current upstream manufacturing capabilities
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Competencies
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A strong interest in gene therapy with emphasis on lentiviral vectors, and/or experience of
working with lentiviral vectors would be an advantage
Good practical competence and technical understanding of lentiviral vector production
Demonstrated ability to work independently as well as in a team setting
Excellent time management skills, with the ability to execute projects to aggressive timelines
and adapt to rapid changes in project priorities
Good written and verbal communication skills
Be enthusiastic and motivated for working on and solving very challenging projects
Effective communication skills to gain company support
The successful candidate will report to the Team Leader for the Cell Engineering Group within the
Research Group.
Please use the cover letter to highlight how you meet the competencies for the role which will be
used along with your CV to assess your application. Please also confirm your current salary and salary
expectations.
With your application could you please quote job reference OXBCEG1 for the permanent position or
OXBMAT1 for the maternity cover position.