CHEM251
Group and Ligand Assignments for Synthesis and Characterization
Group #
Group 1 —
Students
Linda Cho and Katie Guye
ligand
DPPZ
complex
[Ru(bpy)2(DPPZ)](PF6)2
Group 2 —
Rachael Kahlin and Julia Heer
L-allox
[Ru(bpy)2(L-allox)](PF6)2
Group 3 —
Julie Han and Bingqing Li
L-amino
[Ru(bpy)2(L-amino)](PF6)2
Group 4 —
Alicia Makepeace and Misha Sims
L-keto
[Ru(bpy)2(L-keto)](PF6)2
Group 5 —
Terry Huh and Maria Nam
L-keto
[Ru(bpy)2(L-keto)](PF6)2
Group 6 —
Anna Kalinsky and Janielle Vidal
L-keto (to make L-aap)
[Ru(bpy)2(L-aap)](PF6)2
Group 7—
Chloe Baumann and Sara Kim
L-UN (to make L-alap)
[Ru(bpy)2(L-alap)](PF6)2
‘Group’ 8 —
Alexandra Kirsch
L-tallox (thioalloxazine)
[Ru(bpy)2(L-tallox)](PF6)2
Ligand
name on Ru
complex 
DPPZ
Structure
General reaction:
L-allox
L-amino
L-keto
L-aap
L-UN
L-alap
CHEM251
Ligand Syntheses
Ligand
name on Ru
complex 
DPPZ
L-allox
L-amino
L-keto
L-aap
L-UN
L-alap
Ligand
Synthesis
room
temperature,
overnight
MeOH 2 hour
reflux
room
temperature,
overnight
room
temperature
overnight
made from
L-keto ligand
room
temperature,
overnight
made from
L-UN ligand
when
Start 9/12
Isolate 9/13
Do All on
Thurs. Sept 13
Start 9/12
Isolate 9/13
Start 9/12
Isolate 9/13
Start 9/12
Isolate 9/13
Start 9/12
Isolate 9/13
Start 9/12
Isolate 9/13
Structure
Reagents
All reactions
dissolved in
MeOH
(15 mL)
use “phen-dione”

Diamine
.
Diamine
solvent
MeOH
H2SO4
MeOH (20 mL)
H2SO4
½ .H2SO4
H2O , pH 10
(15 mL)
H2O , pH 10
(15 mL)
.
made from
L-keto ligand
made from
L-UN ligand
MeOH (15 mL)
CHEM251
General Ligand Synthesis Procedure (except for L-allox; see below)
Reaction scale is 2.0 mmol using reagents in an equimolar ratio.
Phen dione is dissolved in 15 mL MeOH.
Diamine reagent is dissolved in either MeOH or water made basic with dilute NaOH (see chart for which).
Two reagent solutions combined in round bottom flask.
Mixture is stirred overnight.
Product is isolated by filtration (Hirsch funnel, filter paper).
Product is washed with water, methanol and diethylether.
L-allox synthesis procedure
Reaction scale is 2.0 mmol using reagents in an equimolar ratio.
Both reagents are dissolved in 25 mL MeOH.
Reaction mixture if heated to reflux for two hours.
Product is isolated by filtration (Hirsch funnel, filter paper).
Product is washed with water, methanol and diethylether.
Before arriving to lab you will need:
Calculated masses of reagents.
Prepared labbook