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Baulcombe, D.C. and D.P.S. Verma, Preparation of a complementary DNA for
leghaemoglobin and direct demonstration that leghaemoglobin is encoded by the soybean
genome. Nucleic Acids Res., 1978. 5: p. 4141-4153.
Auger, S., D.C. Baulcombe, and D.P.S. Verma, Sequence complexities of the polyA-containing
RNA in uninfected soybean root and the nodule tissue developed due to infection by
Rhizobium. Biochim.Biophys.Acta, 1979. 563: p. 496-507.
Baulcombe, D.C., J. Giorgini, and J.L. Key, The effect of auxin on the polyadenylated RNA of
soybean hypocotyls., in Genome Organisation and Expression in Plants. NATO ASI Series:
Series A: Life Sciences., C.J. Leaver, Editor. 1980, Plenum. p. 175-185.
Baulcombe, D.C. and J.L. Key, Polyadenylated RNA sequences which are reduced in
concentration following auxin treatment of soybean hypocotyls. J.Biol.Chem., 1980. 255: p.
8907-8913.
Baulcombe, D.C., P.A. Kroner, and J.L. Key, Auxin and gene regulation., in Levels Genetic
Control Development., S.t. Subtelny and U.K. Abbott, Editors. 1981, Alan R. Liss, Inc.: New
York. p. 83-98.
Baulcombe, D.C., Wheat -amylase genes: cloning of a developmentally regulated gene
family., in Genetic Engineering., J. Setlow and A. Hollaender, Editors. 1983, Plenum Press. p.
93-108.
Baulcombe, D.C. and D. Buffard, Gibberellic acid regulated expression of -amylase and six
other genes in wheat aleurone layers. Planta, 1983. 157: p. 493-501.
Baulcombe, D., et al., Recombinant DNA probes for detection of viruses in plants. British Crop
Protection Conference Pests & Disease, 1984. 3B-2: p. 207-213.
Baulcombe, D.C., et al., The sensitivity and specificity of a rapid nucleic acid hybridization
method for the detection of potato virus X in crude sap samples. Plant Pathology, 1984. 33:
p. 361-370.
Baulcombe, D.C., et al., The use of cloned hybridisation probes to detect viral infections in a
potato breeding programme., in The genetic manipulation of plants and its application to
agriculture., P.L. Lea and G.R. Stewart, Editors. 1984, Clarendon Press.: Oxford. p. 183-195.
Baulcombe, D.C., R.A. Martienssen, and C.M. Lazarus, Gibberellins and gene control in cereal
aleurone cells. Journal of Embryology and Experimental Biology, 1984. 83: p. 119-135.
Boulton, R.E., et al., The practical application of complementary DNA probes to virus
detection in a potato breeding programme. British Crop Protection Conference Pests &
Disease, 1984. 3A-2: p. 177-180.
Rothstein, S.J., et al., Secretion of a wheat -amylase expressed in yeast. [Saccharomyces
cerevisiae]. Nature, 1984. 308: p. 662-665.
Baulcombe, D.C., R. Martienssen, and C. Lazarus, -Amylases and gibb-ons: molecular
analysis of co-regulated gene families in wheat., in NATO AIS Series A: Life Sciences. Vol. 83.,
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
L. van Vloten-Doting, G.S.P. Groot, and T.C. Hall, Editors. 1985, Plenum Publishing
Corporation.: New York, London. p. 155-166.
Lazarus, C.M., D.C. Baulcombe, and R.A. Martienssen, -amylase genes of wheat are two
multi-gene families which are differentially expressed. Plant Mol.Biol., 1985. 5: p. 13-24.
Baulcombe, D.C., et al., Hormonal and developmental control of gene expression in wheat.
Philos.Trans.R.Soc.Lond.Ser.B.Biol.Sci., 1986. 314: p. 441-451.
Baulcombe, D.C., et al., Expression of biologically active viral satellite RNA from the nuclear
genome of transformed plants. Nature., 1986. 321: p. 446-449.
Boccara M, Hamilton W D O, and B.D. C, The organisation and interviral homologies of genes
at the 3' end of tobacco rattle virus RNA1. EMBO Journal., 1986. 5(2): p. 223-229.
Boulton, R.E., et al., The application of complementary DNA probes to routine virus
detection, with particular reference to potato viruses., in Developments and Applications in
Virus Testing., R.A.C. Jones and L. Torrence, Editors. 1986, Association of Applied Biologists.
p. 41-53.
Cornford, C.A., et al., Expression of -amylase and other GA-regulated genes in aleurone
tissue of developing wheat grains. Planta, 1986. 169: p. 420-428.
Gatenby, A.A., et al., Expression of a wheat -amylase gene in E coli. Recognition of the
translational initiation site and the signal peptide. Gene, 1986. 45: p. 11-18.
Harrison, B.D., et al., Two contrasting types of host resistance of potential use for controlling
plant viruses. UCLA.Sym.Mol.Cell Biol., 1986. 54: p. 575-585.
Huttly, A. and D. Baulcombe, Subfamily organization in the a-Amy2 genes of wheat. 619th
meeing, Cambridge, 1986. 14: p. 1099.
Baulcombe, D.C., Do plant hormones regulate gene expression during development?, in
Hormone action in plant development: A critical appraisal., G.V. Hoad, et al., Editors. 1987,
Butterworths. p. 63-70.
Baulcombe, D.C., R.F. Barker, and M.G. Jarvis, A gibberellin responsive wheat gene has
homology to yeast carboxypeptidase Y. J.Biol.Chem., 1987. 262: p. 13726-13735.
Baulcombe, D.C., et al., Resistance to viral disease through expression of viral genetic
material from the plant genome., in Plant resistance to viruses. Ciba Foundation., D. Evered
and S. Harnett, Editors. 1987, John Wiley & Sons. p. 170-184.
Baulcombe, D.C., A. Huttly, and R. Martienssen, Hormonal and developmental control of
gene expression in wheat. Trans.Biochem Soc., 1987. 15: p. 9-11.
Baulcombe, D.C., et al., A novel wheat -amylase gene. (alpha-Amy3). Mol.Gen.Genet.,
1987. 209: p. 33-40.
Boulton, R.E., et al., Improved selection for field resistance to potato virus Y and potato
leafroll virus. Potato Research, 1987. 30: p. 161-162.
Boulton, R.E., et al., Complementary DNA probes for the detection of potato viruses. Potato
Research, 1987. 30: p. 166-167.
Hamilton, W.D.O., et al., The complete nucleotide sequence of tobacco rattle virus RNA-1.
J.Gen.Virol., 1987. 68: p. 2563-2575.
Harrison, B.D., M.A. Mayo, and D.C. Baulcombe, Virus resistance in transgenic plants that
express cucumber mosaic virus satellite RNA. Nature, 1987. 328: p. 799-802.
Robinson, D.J., et al., Two anomalous tobravirus isolates: evidence for RNA recombination in
nature. J.Gen.Virol., 1987. 68: p. 2551-2561.
Rothstein, S.J., et al., Synthesis and secretion of wheat -amylase in Saccharomyces
cerecisiae. Gene, 1987. 55: p. 353-356.
Baulcombe, D.C. and E.N. Fernandez-Northcote, Detection of strains of potato virus X and of
a broad spectrum of potato virus Y isolates by nucleic acid spot hybridization (NASH). Plant
Dis., 1988. 72: p. 307-309.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
55.
56.
57.
Baulcombe, D.C., et al., Gibberellin regulated genes of the wheat aleurone layer.
Proceedings.of.the.Seventh.International.Wheat.Genetics Symposium./.edited.by.T.E., 1988:
p. 695-697.
Huttly, A.K., R.A. Martienssen, and D.C. Baulcombe, Sequence heterogeneity and differential
expression of the - Amy2 gene family in wheat. Mol.Gen.Genet., 1988. 214: p. 232-240.
Baulcombe, D.C., Strategies for virus resistance in plants. Trends. Genet., 1989. 5: p. 56-60.
Baulcombe, D.C., et al., Control of viral infection in transgenic plants by expression of
satellite RNA of cucumber mosaic virus. UCLA.Symp.Mol.Cell Biol., 1989. 101: p. 257-267.
Baulcombe, D.C. and R. Hull, Spreading the word. Nature, 1989. 341: p. 189.
Devic, M., M. Jaegle, and D.C. Baulcombe, Symptom production on tobacco and tomato is
determined by two distinct domains of the satellite RNA of cucumber mosaic virus (strain Y).
J.Gen.Virol., 1989. 70: p. 2765-2774.
Hamilton, W.D.O. and D.C. Baulcombe, Infectious RNA produced by in vitro transcription of a
full-length tobacco rattle virus RNA-1 cDNA. J.Gen.Virol., 1989. 70: p. 963-968.
Huttly, A.K. and D.C. Baulcombe, A wheat -Amy2 promotor is regulated by gibberellin in
transformed oat aleurone protoplasts. EMBO J., 1989. 8: p. 1907-1913.
Martienssen, R.A. and D.C. Baulcombe, An unusual wheat insertion sequence (WIS1) lies
upstream of an -amylase gene in hexaploid wheat, and carries a "minisatellite" array.
Mol.Gen.Genet., 1989. 217: p. 401-410.
Baulcombe, D.C., M. Devic, and M. Jaegle, The molecular biology of satellite RNA from
cucumber mosaic virus., in NATO ASI Series: Series H: Cell Biology., R.S.S. Fraser, Editor. 1990,
Springer-Verlag. p. 263-272.
Devic, M., M. Jaegle, and D.C. Baulcombe, Cucumber mosaic virus satellite RNA (strain Y):
analysis of sequences which affect systemic necrosis on tomato. Journal Of General Virology,
1990. 71: p. 1443-1449.
Huttly, A.K. and D.C. Baulcombe, Hormonal control of wheat -amylase genes., in Genetic
engineering in crop plants., G.W. Lycett and D. Grierson, Editors. 1990, Butterworths. p. 171189.
Jaegle, M., et al., Cucumber mosaic virus satellite RNA (Y strain): Analysis of sequences which
affect yellow mosaic symptoms on tobacco. J.Gen.Virol., 1990. 71: p. 1905-1912.
Slakeski, N., et al., Structure and tissue-specific regulation of genes encoding barley (1 ->3, 1 >4)--glucan endohydrolases. Mol.Gen.Genet., 1990. 224: p. 437-449.
Guilford, P.J., V. Ziegler-Graff, and D.C. Baulcombe, Mutation and replacement of the 16K
protein gene in RNA-1 of tobacco rattle virus. Virology, 1991. 182: p. 607-614.
Ziegler-Graff, V., P.J. Guilford, and D.C. Baulcombe, Tobacco rattle virus RNA-1 29K gene
product potentiates viral movement and also affects symptom induction in tobacco. Virology,
1991. 182: p. 145-155.
Boccard, F. and D.C. Baulcombe, Infectious in vitro transcripts from amplified cDNAs of the Y
and Kin strains of cucumber mosaic virus. Gene, 1992. 114: p. 223-227.
Cejudo, F.J., et al., Analysis of the gibberellin-responsive promotor of a cathespin B-like gene
from wheat. Plant Mol.Biol., 1992. 20: p. 849-856.
Cejudo, F.J., et al., A gibberellin-regulated gene from wheat with sequence homology to
cathepsin B of mammalian cells. Plant J., 1992. 2(6): p. 937-948.
Chapman, S., et al., Mutational analysis of the coat protein gene in potato virus X: Effects on
virion morphology and viral pathogenicity. Virology, 1992. 191: p. 223-230.
Chapman, S.N., T.A. Kavanagh, and D.C. Baulcombe, Potato virus X as a vector for gene
expression in plants. Plant Journal, 1992. 2(4): p. 549-557.
Kavanagh, T., et al., Molecular analysis of a resistance-breaking strain of potato virus X.
Virology, 1992. 189: p. 609-617.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
73.
74.
75.
76.
77.
78.
79.
Baulcombe, D.C., et al., Signal for potyvirus-dependent aphid transmission of potato aucuba
mosaic virus and the effect of its transfer to potato virus X. J.Gen.Virol., 1993. 74: p. 12451253.
Boccard, F. and D.C. Baulcombe, Mutational analysis of cis-acting sequences and gene
function in RNA3 of cucumber mosaic virus. Virology, 1993. 193: p. 563-578.
Davies, C., G.J. Hills, and D.C. Baulcombe, Subcellular localisation of the 25kDa protein
encoded by the triple gene block of potato virus X. Virology, 1993. 197: p. 166-175.
Goulden, M.G. and D.C. Baulcombe, Functionally homologous host components recognize
potato virus X in Gomphrena globosa and potato. Plant Cell, 1993. 5: p. 921-930.
Goulden, M.G., et al., A feature of the coat protein of potato virus X affects both induced
virus resistance in potato and viral fitness. Virology, 1993. 197: p. 293-302.
Kohm, B.A., et al., A Potato Virus-X Resistance Gene Mediates an Induced, Nonspecific
Resistance In Protoplasts. Plant Cell, 1993. 5(8): p. 913-920.
Longstaff, M., et al., Extreme resistance to potato virus X infection in plants expressing a
modified component of the putative viral replicase. EMBO J., 1993. 12: p. 379-386.
Santa Cruz, S. and D.C. Baulcombe, Molecular analysis of potato virus X isolates in relation to
the potato hypersensitivity gene Nx. Molecular Plant-Microbe Interactions, 1993. 6: p. 707714.
Baulcombe, D., Replicase-mediated resistance: a novel type of virus resistance in transgenic
plants? Trends Microbiol, 1994. 2(2): p. 60-3.
Baulcombe, D., Plant genetic engineering. Encyclopedia of Molecular Biology, 1994: p. 831834.
Baulcombe, D.C., Replicase mediated resistance: a novel type of virus resistance in transgenic
plants? Trends in Microbiology, 1994. 2: p. 60-63.
Baulcombe, D.C., Novel strategies for engineering virus resistance in plants. Current Opinion
In Biotechnology, 1994. 5: p. 117-124.
Baulcombe, D.C., et al., Molecular biology of resistance to potato virus X in potato. Biochem.
Soc. Symp., 1994. 60: p. 207-218.
Angell, S. and D. Baulcombe, Cell-to-cell movement of potato virus X revealed by microinjection of a viral vector tagged with the B-glucuronidase gene. Plant J., 1995. 7(1): p. 135140.
Baulcombe, D. and Y. Pinto, Genetic transformation of rice for resistance to rice yellow
mottle virus (RYMV). Plant Sciences Research on Semi-Arid Systems; Proceedings of ODA
Plant Sciences, 1995: p. 5.
Baulcombe, D.C., S.N. Chapman, and S. Santa Cruz, Jellyfish green fluorescent protein as a
reporter for virus infections. Plant Journal, 1995. 7(6): p. 1045-1053.
Baulcombe, D.C., et al., A "gene for gene" interaction and potato virus X., in Biotechnology
and Plant Protection: Viral Pathogenesis and Disease., D.D. Bills, et al., Editors. 1995, World
Scientific Publishing: New Jersey. p. 333-351.
Bendahmane, A., et al., The coat protein of potato virus X is a strain-specific elicitor of Rx1mediated virus resistance in potato. Plant J., 1995. 8(6): p. 933-941.
Cejudo, F.J., M.T. Cubo, and D.C. Baulcombe, Amy1 expression during wheat seed
germination. Plant Science, 1995. 106: p. 207-213.
Hammond-Kosack, K.E., et al., Functional expression of a fungal avirulence gene from a
modified potato virus X genome. Molecular Plant-Microbe Interactions, 1995. 8: p. 181-185.
Mueller, E., et al., Homology-dependent resistance: transgenic virus resistance in plants
related to homology-dependent gene silencing. Plant J., 1995. 7(6): p. 1001-1013.
Oparka, K.J., et al., Imaging the green fluorescent protein in plants - viruses carry the torch.
Protoplasma, 1995. 189: p. 133-141.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
92.
93.
94.
95.
96.
97.
98.
Querci, M., et al., Analysis of the resistance-breaking determinant of potato virus X (PVX)
strain HB on different potato genotypes expressing extreme resistance to PVX.
Phytopathology, 1995. 85: p. 1003-1010.
Rommens, C.M.T., et al., Use of a gene expression system based on potato virus X to rapidly
identify and characterize a tomato pto homolog that controls fenthion sensitivity. Plant Cell,
1995. 7: p. 249-257.
Sablowski, R.W.M., D.C. Baulcombe, and M.W. Bevan, Expression of a flower-specific Myb
protein in leaf cells using a viral vector causes ectopic activation of a target promoter.
Proceedings Of The National Academy Of Sciences Of The United States Of America, 1995.
92: p. 6901-6905.
Santa Cruz, S. and D. Baulcombe, Analysis of potato virus X coat protein genes in relation to
resistance conferred by the genes Nx, Nb and Rx1 of potato. J. Gen. Virol., 1995. 76: p. 20572061.
Angell, S.M., C. Davies, and D.C. Baulcombe, Cell-to-cell movement of potato virus X is
associated with a change in the size exclusion limit of plasmodesmata in trichome cells of
Nicotiana clevelandii. Virology, 1996. 215: p. 197-201.
Baulcombe, D. and J.J. English, Ectopic pairing of homologous DNA and post-transcriptional
gene silencing in transgenic plants. Current Opinion In Biotechnology, 1996. 7: p. 173-180.
Baulcombe, D.C., RNA as a target and an initiator of post-transcriptional gene silencing in
transgenic plants. Plant Molecular Biology, 1996. 32(1-2): p. 79-88.
Baulcombe, D.C., Mechanisms of pathogen-derived resistance to viruses in transgenic plants.
Plant Cell, 1996. 8: p. 1833-1844.
Baulcombe, D.C., et al., Gene silencing and virus resistance in transgenic plants., in
Mechanisms and applications of gene silencing. 1996, Nottingham University Press:
Nottingham. p. 127-138.
English, J.J., E. Mueller, and D.C. Baulcombe, Suppression of virus accumulation in transgenic
plants exhibiting silencing of nuclear genes. Plant Cell, 1996. 8: p. 179-188.
Angell, S.M. and D.C. Baulcombe, Consistent gene silencing in transgenic plants expressing a
replicating potato virus X RNA. EMBO J., 1997. 16(12): p. 3675-3684.
Bendahmane, A., K.V. Kanyuka, and D.C. Baulcombe, High resolution and physical mapping
of the Rx gene for extreme resistance to potato virus X in tetraploid potato.
Theor.Appl.Genet., 1997. 95: p. 153-162.
Brigneti, G., J. Garcia-Mas, and D.C. Baulcombe, Molecular mapping of the potato virus Y
resistance gene (Rysto) in potato. Theor.Appl.Genet., 1997. 94: p. 198-203.
Davenport, G.F. and D.C. Baulcombe, Mutation of the GKS motif of the RNA-dependent RNA
polymerase from potato virus X disables or eliminates virus replication. J Gen Virol, 1997. 78 (
Pt 6): p. 1247-1251.
de Jong, W., et al., A potato hypersensitive resistance gene against potato virus X maps to a
resistance gene cluster on chromosome V. Theor.Appl.Genet., 1997. 95: p. 153-162.
Desiderio, A., et al., PGIPs (Polygalacturonase-inhibiting proteins) with different specificities
are expressed in Phaseolus vulgaris L. Molecular Plant-Microbe Interactions, 1997. 10(7): p.
pp.852-860.
English, J.J. and D.C. Baulcombe, The influence of small changes in transgene transcription on
homology-dependent virus resistance and gene silencing. Plant Journal, 1997. 12(6): p. 13111318.
English, J.J., et al., Requirement of sense transcription for homology-dependent virus
resistance and trans-inactivation. The Plant Journal, 1997. 12(3): p. 597-603.
Jakab, G., et al., Infectious in vivo and in vitro transcripts from a full-length cDNA clone of
PVY-N605, a Swiss necrotic isolate of potato virus Y. J.Gen.Virol., 1997. 78: p. 3141-3145.
99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
110.
111.
112.
113.
114.
115.
116.
117.
118.
119.
Morozov, S.Y., et al., Complementation of a potato virus X mutant mediated by
bombardment of plant tissues with cloned viral movement protein genes. J.gen.Virol., 1997.
78: p. 2077-2083.
Ratcliff, F., B.D. Harrison, and D.C. Baulcombe, A similarity between viral defense and gene
silencing in plants. Science, 1997. 276: p. 1558-1560.
Spillane, C., et al., Concurrent Suppression of Virus Replication and Rescue of MovementDefective Virus in Transgenic Plants Expressing the Coat Protein of Potato Virus X. Virology,
1997. 236: p. 76-84.
Voinnet, O. and D.C. Baulcombe, Systemic signalling in gene silencing. Nature, 1997. 389: p.
553.
Brigneti, G., et al., Viral pathogenicity determinants are suppressors of transgene silencing in
Nicotiana benthamiana. EMBO Journal, 1998. 17(22): p. 6739-6746.
Gilbert, J., et al., Elicitation of Rx-mediated resistance to PVX in potato does not require new
RNA synthesis and may involve a latent hypersensitive response. Molecular Plant-Microbe
Interactions, 1998. 8: p. 833-835.
Hamilton, A. and D.C. Baulcombe. Investigations into the use and mechanisms of gene
silencing. in International Congress of Plant Pathology. 1998. Edinburgh.
Marano, M.R. and D. Baulcombe, Pathogen-derived resistance targeted against the
negative-strand RNA of tobacco mosaic virus: RNA strand-specific gene silencing? The Plant
Journal, 1998. 13(4): p. 537-546.
Ruiz, M.T., O. Voinnet, and D.C. Baulcombe, Initiation and maintenance of virus-induced
gene silencing. Plant Cell, 1998. 10: p. 937-946.
Spillane, C., D.C. Baulcombe, and T.A. Kavanagh, Genetic engineering of the potato cultivar
Glenroe for increased resistance to potato virus X (PVX). Irish Journal Of Agricultural and
Food Research, 1998. 37(2): p. 173-182.
Verchot, J., S.M. Angell, and D.C. Baulcombe, In Vivo Translation of the Triple Gene Block of
Potato Virus X Requires Two subgenomic mRNAs. Journal of Virology, 1998. 72(10): p. 83168320.
Voinnet, O., et al., Systemic spread of sequence-specific transgene RNA degradation is
initiated by localised introduction of ectopic promoterless DNA. Cell, 1998. 95(2): p. 177-187.
Angell, S.M. and D.C. Baulcombe, Potato virus X amplicon-mediated silencing of nuclear
genes. The Plant Journal, 1999. 20(3): p. 357-362.
Baulcombe, D.C., Fast forward genetics based on virus-induced gene silencing. Current
Opinion In Plant Biology, 1999. 2(2): p. 109-113.
Baulcombe, D.C., Viruses and gene silencing in plants. Archives Of Virology, 1999. suppl. 15:
p. 189-201.
Baulcombe, D.C., Gene silencing: RNA makes RNA makes no protein. Current Biology, 1999.
9(16): p. R599-R601.
Bendahmane, A., K. Kanyuka, and D.C. Baulcombe, The Rx gene from potato controls
separate virus resistance and cell death responses. Plant Cell, 1999. 11: p. 781-791.
Hamilton, A.J. and D.C. Baulcombe, A species of small antisense RNA in post-transcriptional
gene silencing in plants. Science, 1999. 286: p. 950-952.
Jones, L., et al., RNA-DNA interactions and DNA methylation in post-transcriptional gene
silencing. Plant Cell, 1999. 11: p. 2291-2302.
Kanyuka, K., et al., Mapping of intra-locus duplications and introgressed DNA: aids to mapbased cloning of genes from complex genomes illustrated by analysis of the Rx locus in
tetraploid potato. Theoretical and Applied Genetics, 1999. 98: p. 679-689.
Malcuit, I., et al., The 25-kDa movement protein of PVX elicits Nb-mediated hypersensitive
cell death in potato. Molecular Plant-Microbe Interactions, 1999. 12(6): p. 536-543.
120.
121.
122.
123.
124.
125.
126.
127.
128.
129.
130.
131.
132.
133.
134.
135.
136.
137.
138.
139.
Pinto, Y.M., R.A. Kok, and D.C. Baulcombe, Resistance to rice yellow mottle virus (RYMV) in
cultivated African rice varieties containing RYMV transgenes. Nature Biotechnology, 1999.
17(7): p. 702-707.
Ratcliff, F.G., S.A. MacFarlane, and D.C. Baulcombe, Gene silencing without DNA. RNAmediated cross-protection between viruses. Plant Cell, 1999. 11(7): p. 1207-16.
van der Voort, J.R., et al., Tight physical linkage of the nematode resistance gene Gpa2 and
the virus resistance gene gene Rx on a single segment introgressed from the wild species
Solanum tuberosum subsp. andigena CPC 1673 into cultivated potato. Molecular PlantMicrobe Interactions, 1999. 12(3): p. 197-206.
Voinnet, O., Y.M. Pinto, and D.C. Baulcombe, Suppression of gene silencing: a general
strategy used by diverse DNA and RNA viruses. Proceedings Of The National Academy Of
Sciences Of The United States Of America, 1999. 96(24): p. 14147-14152.
Baulcombe, D.C., Unwinding RNA silencing. Science, 2000. 290(5494): p. 1108-1109.
Bendahmane, A., et al., Agrobacterium transient expression system as a tool for the isolation
of disease resistance genes: application to the Rx2 locus in potato. Plant Journal, 2000. 21(1):
p. 73-81.
Burton, R.A., et al., Virus-induced silencing of a plant cellulose synthase gene. Plant Cell,
2000. 12: p. 691-705.
Dalmay, T., et al., Potato Virus X amplicons in arabidopsis mediate genetic and epigenetic
gene silencing. Plant Cell, 2000. 12(3): p. 369-379.
Dalmay, T., et al., An RNA-dependent RNA polymerase gene in Arabidopsis is required for
posttranscriptional gene silencing mediated by a transgene but not by a virus. Cell, 2000.
101(5): p. 543-553.
Malcuit, I., et al., Acquisition of multiple virulence/avirulence determinants by potato virus X
(PVX) has occurred through convergent evolution rather than through recombination. Virus
Genes, 2000. 20(2): p. 165-172.
Mestre, P., G. Brigneti, and D.C. Baulcombe, An Ry-mediated resistance response in potato
requires the intact active site of the NIa proteinase from potato virus Y. Plant Journal, 2000.
23(5): p. 653-661.
van der Vossen, E.A.G., et al., Homologues of a single resistance-gene cluster in potato
confer resistance to distinct pathogens: a virus and a nematode. The Plant Journal, 2000.
23(5): p. 567-576.
Voinnet, O., C. Lederer, and D.C. Baulcombe, A viral movement protein prevents spread of
the gene silencing signal in Nicotiana benthamiana. Cell, 2000. 103: p. 157-167.
Yang, Y., et al., Cell-to-cell movement of the 25k protein of potato virus X is regulated by
three other viral proteins. Molecular Plant-Microbe Interactions, 2000. 13(6): p. 599-605.
Baulcombe, D.C., Diced defence. Nature, 2001. 409: p. 295-296.
Dalmay, T.D., et al., SDE3 encodes an RNA helicase required for post-transcriptional gene
silencing in Arabidopsis. EMBO Journal, 2001. 20(8): p. 2069-2078.
Jones, L., F. Ratcliff, and D.C. Baulcombe, RNA-directed transcriptional gene silencing in
plants can be inherited independently of the RNA trigger and requires Met1 for maintenance.
Current Biology, 2001. 11: p. 747-757.
Papaefthimiou, I., et al., Replicating potato spindle tuber viroid RNA is accompanied by short
RNA fragments that are characteristic of post-transcriptional gene silencing. Nucleic Acids
Research, 2001. 29(11): p. 2395-2400.
Ratcliff, F., A.M. Martin-Hernandez, and D.C. Baulcombe, Tobacco rattle virus as a vector for
analysis of gene function by silencing. Plant Journal, 2001. 25(2): p. 237-245.
Thomas, C.L., et al., Size constraints for targeting post-transcriptional gene silencing and for
RNA-directed methylation in Nicotiana benthamiana using a potato virus X vector. Plant
Journal, 2001. 25(4): p. 417-425.
140.
141.
142.
143.
144.
145.
146.
147.
148.
149.
150.
151.
152.
153.
154.
155.
156.
157.
158.
159.
160.
161.
162.
163.
164.
Abbink, T.E.M., et al., Silencing of a gene encoding a protein component of the oxygenevolving complex of photosytem II enhances virus replication in plants. Virology, 2002.
295(2): p. 307-319.
Baulcombe, D.C., RNA silencing. Current Biology, 2002. 12(3): p. R82-R84.
Baulcombe, D.C., Viral suppression of systemic silencing. Trends in Microbiology, 2002. 10(7):
p. 306-308.
Baulcombe, D.C., An RNA microcosm. Science, 2002. 297.
Bendahmane, A., et al., Constitutive gain-of-function mutants in a nucleotide binding siteleucine rich repeat protein encoded at the Rx locus of potato. Plant Journal, 2002. 32: p. 195204.
Bouarab, K., et al., A saponin-detoxifying enzyme mediates suppression of plant defences.
Nature, 2002. 418: p. 889-892.
Hamilton, A.J., et al., Two classes of short interfering RNA in RNA silencing. EMBO Journal,
2002. 21(17): p. 4671-4679.
Mallory, A.C., et al., The amplicon-plus system for high-level expression of transgenes in
plants. Nature Biotechnology, 2002. 20(6): p. 622-625.
Marano, M.R., et al., High-resolution genetic map of Nb, a gene that confers hypersensitive
resistance to potato virus X in Solanum tuberosum. Theoretical And Applied Genetics, 2002.
105: p. 192-200.
Moffett, P., et al., Interaction between domains of a plant NBS-LRR protein in disease
resistance-related cell death. EMBO Journal, 2002. 21(17): p. 4511-4519.
Peart, J.R., et al., An EDS1 orthologue is required for N-mediated resistance against tobacco
mosaic virus. Plant Journal, 2002. 29(4): p. 569-579.
Peart, J.R., et al., Ubiquitin ligase-associated protein SGT1 is required for host and nonhost
disease resistance in plants. Proceedings Of The National Academy Of Sciences Of The
United States Of America, 2002. 99(16): p. 10865-10869.
Vaistij, F.E., L. Jones, and D.C. Baulcombe, Spreading of RNA targeting and DNA methylation
in RNA silencing requires transcription of the target gene and a putative RNA-dependent RNA
polymerase. Plant Cell, 2002. 14(4): p. 857-867.
Armfield, S., et al., Biotech 2020: Crop Biotechnology in the World of 2020. 2003. p. 48.
Lu, R., et al., High throughput virus-induced gene silencing implicates heat shock protein 90
in plant disease resistance. EMBO Journal, 2003. 22(21): p. 5690-5699.
Lu, R., et al., Virus-induced gene silencing in plants. Methods, 2003. 30: p. 296-303.
Mestre, P., et al., Potato virus Y NIa protease activity is not sufficient for elicitation of Rymediated disease resistance in potato. Plant Journal, 2003. 36: p. 755-761.
Pe'ery, T., M.B. Mathews, and D. Baulcombe, RNA interference. Methods, 2003. 30: p. 287288.
Voinnet, O., et al., An enhanced transient expression system in plants based on suppression
of gene silencing by the p19 protein of tomato bushy stunt virus. Plant Journal, 2003. 33(5):
p. 949-956.
Achard, P., et al., Modulation of floral development by a gibberellin-regulated microRNA.
Development, 2004. 131(14): p. 3357-3365.
Baulcombe, D., RNA silencing in plants. Nature, 2004. 431(7006): p. 356-363.
Baulcombe, D.C. and A. Molnar, Crystal structure of p19 - a universal suppressor of RNA
silencing. Trends in Biochemical Sciences, 2004. 29(6): p. 279-281.
Brigneti, G., et al., Virus-induced gene silencing in Solanum species. Plant Journal, 2004.
39(2): p. 264-272.
Herr, A.J. and D. Baulcombe, RNA Silencing Pathways in Plants. Cold Spring Harbor Symposia,
2004. LXIX: p. 363-370.
Arazi, T., et al., Cloning and characterization of micro-RNAs from moss. The Plant Journal,
2005. 43: p. 837-848.
165.
166.
167.
168.
169.
170.
171.
172.
173.
174.
175.
176.
177.
178.
179.
180.
181.
182.
183.
184.
185.
186.
187.
Baulcombe, D., RNA silencing. Trends In Biochemical Sciences, 2005. 30(6): p. 290-293.
Baumberger, N. and D.C. Baulcombe, Arabidopsis ARGONAUTE1 is an RNA Slicer that
selectively recruits micro RNAs and short interfering RNAs. Proceedings Of The National
Academy Of Sciences Of The United States Of America, 2005. 102(33): p. 11928-11933.
Bayne, E.H., et al., Cell-to-cell movement of Potato Potexvirus X is dependent on suppression
of RNA silencing. Plant Journal, 2005. 44: p. 471-482.
Billoud, B., et al., Identification of new small non-coding RNAs from tobacco and Arabidopsis.
Biochimie, 2005. 87: p. 905-910.
Chappell, L., D. Baulcombe, and A. Molnar, Isolation and cloning of small RNAs from virusinfected plants. Current Protocols in Microbiology, 2005. John Wiley & Sons, Hoboken NJ: p.
16H.2.1-16H.2.17.
Herr, A.J., et al., RNA polymerase IV directs silencing of endogenous DNA. Science, 2005. 308:
p. 118-120.
Peart, J., et al., NRG1, a CC-NB-LLR protein mediates resistance against tobacco mosaic virus
together with N, a TIR-NB-LRR protein. Current Biology, 2005. 15: p. 968-973.
Schwach, F., et al., An RNA-dependent RNA-polymerase prevents meristem invasion by
Potato virus X and is required for the activity but not the production of a systemic silencing
signal. Plant Physiology, 2005. 138: p. 1842-1852.
Baulcombe, D., Short Silencing RNA: The Dark Matter of Genetics? Cold Spring Harbor
Symposia on Quantitative Biology, 2006. LXXI: p. 13-20.
Farnham, G. and D. Baulcombe, Artificial evolution extends the spectrum of viruses that are
targeted by a disease-resistance gene from potato. Proceedings Of The National Academy Of
Sciences Of The United States Of America, 2006. 103: p. 18828-18833.
Herr, A.J., et al., Defective RNA processing enhances RNA silencing and accelerates flowering
in Arabidopsis. Proceedings Of The National Academy Of Sciences Of The United States Of
America, 2006. 103(41): p. 14994-15001.
Mestre, P. and D. Baulcombe, Elicitor-mediated oligomerization of the Tobacco N Disease
Resistance Protein. The Plant Cell, 2006. 18: p. 491-501.
Talmore-Neimen, M., et al., Identification of trans-acting siRNAs in moss and an RNAdependent RNA polymerase required for their biogenesis. The Plant Journal, 2006. 48: p. 511521.
Baulcombe, D., Amplified Silencing. Science, 2007. 315: p. 199-200.
Baulcombe, D., David Baulcombe. Curr Biol, 2007. 17(3): p. R73-4.
Baumberger, N., et al., The Polerovirus silencing suppressor PO targets argonaute proteins
for degradation. Current Biology 2007.
Baurle, I., et al., Widespread role for the flowering time regulators FCA and FPA in siRNAdirected chromatin silencing. in press, 2007.
Boccara, M., et al., New approaches for the analysis of Arabidopsis thaliana small RNAs.
Biochimie, 2007. doi:10.1016/j.biochi.2007.04.011.
Hernandez-Pinzon, I., et al., SDE5, the putative homologue of a human mRNA export factor,
is required for transgene silencing and accumulation of trans-acting endogenous siRNA. The
Plant Journal, 2007. 50: p. 140-148.
Molnar, A., et al., miRNAs control gene expression in single cell alga Chlamydomonas
reinhardtii. Nature, 2007. 447(doi:10.1038/nature05903): p. 1126-1129.
Searle, I.R., et al., Small RNAs hit the big time. New Phytologist, 2007. 174: p. 479-482.
Smith, L.M. and D.C. Baulcombe, Dissection of silencing signal movement in Arabidopsis.
Plant Signal Behav, 2007. 2(6): p. 501-2.
Smith, L.M., et al., A novel SNF2 protein associated with nuclear RNA silencing and spread of
a silencing signal between cells in Arabidopsis. Plant Cell, 2007. 19: p. doi:
10.1105/tpc.107.051540
188.
189.
190.
191.
192.
193.
194.
195.
196.
197.
198.
199.
200.
201.
202.
203.
204.
205.
206.
207.
208.
209.
Tameling, W.I.L. and D. Baulcombe, Physical association of the NB-LRR resistance protein Rx
with a Ran GTPase activating protin is required for extreme resistance to potato virus X. Plant
Cell, 2007. 19: p. 10.1105/tpc.107.050880
Baulcombe, D., Of maize and men, or peas and people: case histories to justify plants and
other model systems. Nat Med, 2008. 14(10): p. 1046-1049.
Buhtz, A., et al., Identification and characterization of small RNAs from the phloem of
Brassica napus. Plant J, 2008. 53(5): p. 739-749.
Martin-Hernandez, A.M. and D.C. Baulcombe, Tobacco rattle virus 16-kilodalton protein
encodes a suppressor of RNA silencing that allows transient viral entry in meristems. Journal
of Virology, 2008. 82(8): p. 4064-4071.
Meyers, B.C., et al., Criteria for Annotation of Plant MicroRNAs. Plant Cell, 2008. 20(12): p.
3186-3190.
Mosher, R.A. and D.C. Baulcombe, Bacterial pathogens encode suppressors of RNA-mediated
silencing. Genome Biology, 2008. 9(10).
Mosher, R.A., et al., PolIVb influences RNA-directed DNA-methylation independently of its
role in siRNA biogenesis. Proceedings of the National Academy of Sciences of the United
States of America, 2008. 105(8): p. 3145-3150.
Preuss, S.B., et al., Multimegabase Silencing in Nucleolar Dominance Involves siRNA-Directed
DNA Methylation and Specific Methylcytosine-Binding Proteins. Molecular Cell, 2008. 32(5):
p. 673-684.
Djupedal, I., et al., Analysis of small RNA in fission yeast; centromeric siRNAs are potentially
generated through a structured RNA. Embo Journal, 2009. 28(24): p. 3832-3844.
Huang, L.F., et al., An atypical RNA polymerase involved in RNA silencing shares small
subunits with RNA polymerase II. Nat Struct Mol Biol, 2009. 16(1): p. 91-93.
Molnar, A., et al., Highly specific gene silencing by artificial microRNAs in the unicellular alga
Chlamydomonas reinhardtii. Plant Journal, 2009. 58(1): p. 165-174.
Mosher, R.A., et al., Uniparental expression of PolIV-dependent siRNAs in developing
endosperm of Arabidopsis. Nature, 2009. 460(7252): p. 283-U151.
Baulcombe, D., Reaping Benefits of Crop Research. Science, 2010. 327(5967): p. 761-761.
Baulcombe, D.C. and P.D. Zamore, Welcome to silence. Silence, 2010. 1(1): p. 1.
Boccara, M., et al., Analysis of small RNA populations using hybridization to DNA tiling
arrays. Methods Mol Biol, 2010. 631: p. 75-86.
Chen, H.-M., et al., 22-nucleotide RNAs trigger secondary siRNA biogenesis in plants.
Proceedings of the National Academy of Sciences, 2010. 107(34): p. 15269-15274.
Chiu, M.H., et al., The silencing suppressor P25 of Potato virus X interacts with Argonaute1
and mediates its degradation through the proteasome pathway. Molecular Plant Pathology,
2010. 11(5): p. 641-649.
Godman, J.E., et al., RNA silencing of hydrogenase(-like) genes and investigation of their
physiological roles in the green alga Chlamydomonas reinhardtii. Biochem J, 2010. 431(3): p.
345-51.
Havecker, E.R., et al., The Arabidopsis RNA-Directed DNA Methylation Argonautes
Functionally Diverge Based on Their Expression and Interaction with Target Loci. Plant Cell,
2010. 22(2): p. 321-334.
MacLean, D., et al., Evidence for Large Complex Networks of Plant Short Silencing RNAs. PLoS
One, 2010. 5(3).
Molnar, A., et al., Small Silencing RNAs in Plants Are Mobile and Direct Epigenetic
Modification in Recipient Cells. Science, 2010. 328(5980): p. 872-875.
Pretty, J., et al., The top 100 questions of importance to the future of global agriculture.
International Journal of Agricultural Sustainability, 2010. 8(4): p. 219-236.
210.
211.
212.
213.
214.
215.
Searle, I.R., et al., JMJ14, a JmjC domain protein, is required for RNA silencing and cell-to-cell
movement of an RNA silencing signal in Arabidopsis. Genes & Development, 2010. 24(10): p.
986-991.
Yelina, N.E., et al., Putative Arabidopsis THO/TREX mRNA export complex is involved in
transgene and endogenous siRNA biosynthesis. Proc Natl Acad Sci U S A, 2010. 107(31): p.
13948-53.
Harvey, J.J.W., et al., An Antiviral Defense Role of AGO2 in Plants. Plos One, 2011. 6(1).
Molnar, A.M.A., C. Melnyk, and D.C. Baulcombe, Silencing signals in plants: a long journey
for small RNAs. Genome Biology, 2011. 12(1).
Rhind, N., et al., Comparative Functional Genomics of the Fission Yeasts. Science, 2011.
332(6032): p. 933-939.
Valli, A., et al., The specific binding to 21-nt double-stranded RNAs is crucial for the antisilencing activity of Cucumber vein yellowing virus P1b and perturbs endogenous small RNA
populations. RNA -a Publication of the Rna Society, 2011. 17(6): p. 1148-1158.