tablets poisoning

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Organophosphate poisoning management

Patient may present with

 Constricted pupils

 Cold sweats

 Difficulty in breathing and excessive salivation

 Convulsions

 Bradycardia or tachycardia

 Abdominal pain, diarrhoea, vomiting

Management

ALWAYS WEAR GLOVES WHEN HANDLING THE PATIENT

Remove contaminated clothes and wash contaminated skin with lots of cold water

Give oxygen

Do not induce vomiting

Consider gastric lavage if within 2 hours of ingestion

 Left lateral position with head down, pass a large e.g. 24 gauge tube through the mouth into the stomach, then give 10 ml/kg N.Saline through the tube, and aspirate, with the patient in the head down position, carefully protect the airway during the procedure

Give activated charcoal –

 25-50 grams of charcoal – grind tablets into powder and mix with 100-

200 mls of water

 Give via NGT if not able to swallow

Atropine – 20 mcg/kg IV (or IM if not able to get IV access) every 15 minutes until reduced secretions, hot dry skin and dry mouth

Do give atropine until the pupils have dilated – this may cause atropine toxicity

Observe for seizures and treat with IV/PR diazepam and load with phenobarbitone 15mg/kg if necessary (seizures continuing despite two doses of diazepam given at least 10 minutes apart)

Paraffin poisoning

Paraffin is poorly absorbed in the GI tract but if aspiration occurs this can cause pneumonitis – cough, tachypnea, tachycardia, cyanosis, crepitations and ronchi.

 Do not induce vomiting, do not perform gastric lavage– may cause aspiration and pneumonitis

 Check saturations and give oxygen if necessary

 No role for activated charcoal

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