CURRICULUM VITAE
1. Name: AP Dr. Maizan Mohamed
2. Date of Birth and I. C. No./Passport: 22/06/1964
3. Work Address: Fakulti Perubatan Veterinar, Universiti Malaysia Kelantan,Beg
Berkunci 36,16100 Pengkalan Chepa, Kota Bharu, Kelantan
Tel. No.: +609-7717133
Fax No.: +609-7717132
Mobile Phone No.: +609-1119741914
E-mail Address: maizan.m@umk.edu.my
4. Academic Qualifications:
Degree
BSc.(Hons) Microbiology
2nd Class Upper
MSc in Molecular Virology
Institution
Year
UKM, Bangi, Malaysia
1991
UPM, Serdang, Selangor
2001
Ph.D
Univ. of St. Andrews, UK
Life Sciences-Molecular Virology
5. Brief Career History:
Place/appointment
Period
Department of Microbiology, UPM
(Research Assistant)
Mammalian Virology Section
1990-1991
Avian Virology Section, VRI Ipoh
1997-1999
Head of Avian Virology Section, VRI
2000-2003
Ph D student at Glasgow/St.Andrews
University, UK
2003-2007
1991-1996
2007
Head of Molecular/ Avian Virology, VRI
2008-8/2009
INFORMM, USM Senior Lecturer lecturer
8/2009-9/2014
Associate Prof at Fakulti Perubatan Veterinar,
UMK
10/2015-Current
6. Field(s) of Specialization:
-Development of molecular diagnostic tests
-Development of animal viral vaccine
-Virus diagnosis, isolation and assay
-Virus characterization
-Molecular epidemiology study
-Biomarkers Determination for pathogen
-Antiviral assay
7. Current Research Areas/Topics:
1. Screening of anti-Dengue virus activity of seven Malaysian plant extracts
(Co-Researcher-RU short-Term)
2. Genetic diversity of HIV viruses and host genetic factor influencing disease
progression CCR5 receptor gene of HIV-1 patients from Kelantan (Principal
Investigator-RU short-term)
3. Establishment of reverse transcription-loop amplification (LAMP) method for
genotyping and viral load determination assay of Human immunodeficiency virus
(HIV)
(Principal investigator-RU Cluster)
4. Interdisciplinary focused efforts towards H1N1 drug discovery: the study of local
(Malaysian strain) H1N1 ie characterization H1N1 biology toward understanding
viral infections, in parallel with design, synthesis and development of hit compounds
against H1N1-flu related infection (Co-Researcher-E-Science))
5. Establishment of loop amplification (LAMP) method for the diagnosis of
Salmonella Typhi (Principal investigator-HICoE)
6. Genetic variation and molecular epidemiology of Salmonella Typhi isolated from
Kelantan (Principal investigator-RU individu)
7. Establishment of loop amplification (LAMP) method for the detection of
Salmonella Typhi and Salmonella paratyphi A (Principal investigator-RU
Cluster)
8. Number of Postgraduate Students Supervised:
Program
Status
PhD
Graduated
Ongoing
Graduated
Ongoing
Graduated
Ongoing
Masters
(with thesis)
BSC Final Year
Project
As a
Chairman
As a Member
1
3
1
6
-
3
1
1
-
A. On-going Students (MSc and PhD)
i. Ms Fadhilah Mohd Usuki (PhD)
ii. Ms Aziana (PhD) Ismail (PhD)
iii. Dr. Wan Nazirah Wan Yusuf (PhD)
iv.Mr. Foo Phiaw chong (PhD)
v. Ms CW Salma CW Zalati (MSc)
vi. Ms. Engku Nur shafirah Engku Abdul Rahman
B. Graduated students
a). MSc.
i. Ms Julia Abdullah (INFORMM, USM)
ii. Ms Nur Eliana Saffie(INFORMM, USM)
iii. Ms Rasyada A. Rahman (INFORMM, USM)
iv.Ms Ayunni Salleh (Pharmacology, USM)
b). B.Sc (Biomedical,PPSK)
i.Ms.Nurhidatun Annuar Rigos (2010)
ii.Ms. Siti Nur Aishah Mat Yusuf (2011)
iii.Ms. Noor Hamizah Minal(2012)
iv.Ms. Hii Siew Ching (2012)
v. Ms.Ong Sii Min (2012)
vi. Ms Nadia Mustapha
9. Examiner
MSc. Student
1. Miss Fadhilah Kamaruzzaman 2011(INFORMM)
2. Miss Faizah Harun MSc 2012 (INFORMM)
3..Miss Madihah Basuni MSc 2012 (INFORMM)
4. Miss Chua Siew Ling MSc 2012 (PPSK, USM)
5. Mr Low Kim Fatt PhD 2014 (PPSP, USM)
6. Miss Hemavathy AP Harikrisnan MSc 2015 (PPSP, USM)
9. Achievements / Awards:
Excellence services of Department of Veterinary Services 2007
Most Favourite Lecturer INFORMM 2011, USM
Gold medal for BSc final year project in Novel Research and Innovation
Competition (NRIC 2014) entitle’ Effect of mangrove crab soup extract on dengue
virus serotype-2, platelet cell activity and U937 human monocyte cancer cell line’.
10. List of Publications :
a. Journals
1.M. Maizan, S. Nur Eliana, D. Zawiyah, , A. Julia, S. Faizul-Rahman, AR Zaidah, H. Azura, I
Aziah, I Asma. (2014). In-house Loop Amplification (LAMP) method for the diagnosis of
Salmonella Paratyphi A in low-resource settings. Asian Pacific J of Trop Dis 4 (3):251
2. Nur-Eliana Saffie, Julia Abdullah, Maizan Mohamed. (2014). Establishment of an inhouse loop-mediated isothermal amplification (LAMP) for a rapid detection of Salmonella
Typhi and Salmonella Paratyphi A at low-resource settings. Journal of Food Safety 34: 6975.
3. A. Julia, S. Nur Eliana, H. Azura, AR Zaidah, H. Haslizai, A Ismail, I Aziah, M.
Maizan. Evaluation of In-house Loop Amplification (LAMP) method for the diagnosis
of Salmonella Typhi based on StgB gene. Asian Pacific J of Trop Dis 4 (3):224
4. J. Abdullah, N. Saffie, M. Mohamed. (2014). Rapid detection of Salmonella Typhi by
loop-mediated isothermal amplification (LAMP) method. Brazilian journal of Microbiology
45 (4): 1385-1391
5. Maizan M, Nurfadhillah MU, Tan SC. Sequence variation and co-receptor tropism
prediction of V3 loop of HIV-1 from Kelantan, Malaysia.-Accepted for publication in
International Journal of Microbiology and Immunology Research
6. Maizan M, C.W. Salma CWZ, Fadhilah K, Zaidah AR, and Phua KK. (2014). Detection
of mutation in QRDR of gyrA gene of drug-resistant Salmonella Typhi isolates from
Kelantan, Malaysia using PCR-RFLP and DNA sequencing. International journal of Medical
Sciences and Biotechnology 6 : 27-36
7. Rasyada AR., Aziana I, Shaharum S and Maizan M. (2014). Expression and cytotoxic
effect of purified HlyE recombinant protein of Salmonella enterica serovar Typhi on U937
human monocytic cell . International Journal of Microbiology and Immunology Research
Vol. 2(2): 015-023
8. Vinod RMT Balasubramaniam, Sharifah S Hassan, Abdul R Omar, Maizan Mohamed,
Suriani M. Noor, Ramlan Mohamed and Iekhsan Othman . Cellular transcripts regulated
during infections with Highly Pathogenic H5N1 Avian Influenza virus in 3 host
systems.Virology Journal 8:196
9. Sohayati A. Rahman, Sharifah S. Hassan,Kevin J. Olival, Maizan Mohamed, Li-Yen
Chang, Latiffah Hassan, Norsharina M. Saad, Syamsiah A. Shohaimi, Zaini C. Mamat, M.S.
Naim, Jonathan H. Epstein, Arshad S. Suri, Hume E. Field, Peter Daszak, and the
Henipavirus Ecology Research Group. (2010). Characterization of Nipah Virus from
Naturally Infected Pteropus vampyrus Bats, Malaysia. Emerging Infectious Diseases
16:1990-1993
10. Rasoli M, Omar AR, Aini I, Jalilan B, Syed Hassan SH, Mohamed M. (2010). Fusion of
HSP70 gene of Mycobacterium tuberculosis to hemagglutinin (H5) gene of avian influenza
virus in DNA vaccine enhances its potency. Acta Virol. 54:33-39 (impact factor; 0.7).
11. Sharifah, S.H., Sohayati, A.R., Maizan, M., Chang, L.Y., Sharina, M., ak
Syamsiah, A.K., Latiffah, K., Arshad, S.S., Zaini, C.M., Humes, F., Daszak, P.and
Epstein, J. (2009). Genetic characterization of a nipah virus isolated from
Pteropus vampyres in Malaysia. Neurology Asia: 67-69
12. M.Mohamed, N.F.Kamaruzzaman, K.K.Phua. Molecular epidemiology of 3 household
transmissions of Salmonella Typhi in Kelantan, Malaysia. International J of infectious
diseases. . Bangkok convention Center, 13-16 June 2012. Abstract no.:55.027
13. Maizan Mohamed, Angela Mclees, and Richard M. Elliot. (2009). Viruses in the
Anopheles A, Anopheles B, and Tete serogroups in the orthobunyavirus genus (family
bunyaviridae) do not encode an NSs protein. Journal of Virology 83: 7612-7618
14. Maizan, M., Mohd. Ali, A.R. & Sharifah, S.H. (2000). Identification and distinction
between nipah virus and hendra virus using RT-PCR, sequencing and restriction enzyme
analysis. Asia-Pacific J. Mol. Biol. and Biotech, 8(2):126-129
15. Kono, Y., Yusnita, Y., Mohd Ali, A.R. Maizan, M., Sharifah, S.H., Fauziah, O., Kubo,
M. & Aziz, A.J. (2002). Characterization and identification of Oya virus, a Simbu serogroup
virus of the genus bunyavirus, isolated from a pig suspected of nipah virus infection. Arch.
Virol. 147:1623-1630
16. S.H. Sharifah, M.N. Suriani, M. Maizan, G.H. Ong, D. Azizah, K. Suzana, A.R. Omar
and I. Aini (2013). Potency and efficacy of a low pathogenic H5N2 inactivated vaccine
against challenge with a Malaysian H5N1 highly pathogenic avian influenza virus. Jurnal
Veterinar Malaysia, 25 (1): 1-6.
17. S.H. Sharifah, K. Hasuzana, M.N. Suriani, M. Maizan, G.H.. Ong, D. Azizah, A.R. Omar
and I.Aini (2013). Moderately-high humoral antibody responses to a H5N2 inactivated
vaccine did not suppress shedding of highly pathogenic H5N1 Avian Influenza virus during
challenge. Jurnal Veterinar Malaysia 25 (1): 27-30
18. Maizan, M., Abdul Aziz, H., Sharifah, S.H. and Loganathan, P. (1994). Isolation of
Parainfluenza type 3 and Ovine Herpes Viruses associated with respiratory disease complex
in sheep. J. Vet. Malaysia 6 (1):43-45.
19. Sharifah, S.H., Mohd. Ali, A.R., Hussin, A.A.,Maizan, M. and Zainal, M. (1994).
Experimental infection of sheep with Malaysian bluetongue virus isolates. J. Vet. Malaysia,
6(2):95-97.
b) Book
1. Prabha Balaram, Maizan Mohamed, Venugopal Balakrishnan, Rasyada A. Rahman,
Nurfadhlina Musa, Angeline Torey Ayah Torey, Norsyahida Arifin and Lim Bee Nar. The
Journey: Scientific Discoveries to Diagnostics. ISBN 978-983-44297-5—1
c) Selected Proceedings
1.Maizan M, Che Salma CWZ, Fadhilah K, Zaidah AR, Haslizai H,and Phua KK.
Sequence Analysis Of Quinolone And Fluoroquinolone-Resistant Salmonella Typhi Isolates
From Kelantan Malaysia. International Conference on Medical and Health Sciences
(ICMHS) 2013,Renaissance Hotel, 22-24 May 2013. Pp 320
2.Julia A., Nur-Eliana S., Azura H., Zaidah AR., Asma A., Aziah I., Maizan M. Evaluation
of in-house Loop Amplification method for the diagnosis of Salmonella Typhi based on Stg
B gene. 1st International Conference on Molecular diagnostics and Biomarker discovery. 2325 October 2013. Pp 30
3. Maizan M., Nur-Eliana S., Julia A., Faizul-Rahman, S, Azura H., Zaidah AR., Aziah I.
and Asma I. In-house Loop Amplification method for the diagnosis of Salmonella Paratyphi
A in low-resource settings. 1st International Conference on Molecular diagnostics and
Biomarker discovery. 23-25 October 2013. Pp 99.
4.Julia Abdullah., Nur-Eliana Saffie., Azura Husin., Zaidah Abdul-Rahman., Asma Ismail,
Aziah Ismail and Maizan Mohamed. Salmonella Typhi Smart LAMP. 21st International
Conference ‘Biodetection technologies 2013’. Alexandria, VA, USA. 18-19 june 2013.
5. Maizan M, Aishah MY, Wan Nazirah WY. Phylogenetic Relationships and Subtyping of
HIV-1 viruses from Kelantan, Malaysia. 7th National infectious disease seminar and
workshop.Universiti Putra Malaysia. 6 November 2012
6. Julia A., Nur Eliana S., Haslizai H., Maizan M. and Ismail A. Establish of a LoopMediated Amplification (LAMP) Method for the Diagnostics of Salmonella Typhi. 1st
National Postgraduates Conference on Molecular Medicine.The Journey: Scientific
Discoveries to Diagnostics., Renaissance Hotel, Kota Bharu Kelantan. (Oral). 13-14 April
2011.
7. Nur Eliana S., Maizan M., Julia A., and Ismail A. Establishment of a Loop-Mediated
Amplification (LAMP) Method for the Diagnosis of Salmonella Typhi and Salmonella
Paratyphi A. 4th Regional Conference on Molecular Medicine 2011 at G Hotel Penang. 9-11
Oct. 2011 (Oral)
8. Maizan M, Che Zairieha CZ, Nur Farahin G., W. Kamarulzaman WI, Eliana S, Rafidah
Hanim S and Fitrien H. Establishment of a RT-Heminested PCR for the Detection of Dengue
Virus Serotypes. 4th Regional Conference on Molecular Medicine 2011 at G Hotel Penang.
9-11 Oct. 2011 (Oral)
9. Julia A., Nur Eliana S., Haslizai H, Ismail A., and Maizan M. Evaluation of 50kda Gene
for the Diagnosis of Salmonella Typhi by Loop-Mediated Amplification (LAMP) Method.
4th Regional Conference on Molecular Medicine 2011 at G Hotel Penang. 9-11 Oct. 2011
(Poster)
10. Maizan M., Julia A., Aziah I. and Asma I. Development of multiplex PCR for the
detection and identification of Salmonella Typhi from other Salmonellae and
Enterobacteriaceae. 1st AMDI International Biohealth Science Conference (IBSC), Bayview
Beach Resort, Penang; 29 Nov -1 Dec 2010
11. Ong Geok Huai, Maizan Mohamed, Suriani Mohd. Noor, Syamsiah Aini Shohaimi,
Ramlan Mohamed. Development of an indirect avian influenza ELISA using Malaysian local
isolate H5N2. Proceeding of the 22nd Veterinary Association Malaysia Congress & 4th
Wildlife Society of Zoo and Wildlife Medicine, pp. 97-99.K. Lumpur; 30 July -1 Aug 2010
12. M.Maizan, M.N. Norhani, G.H. Ong and S. Syamsiah. Characterisation of Influenza
virus isolated from swine in Malaysia. Proceeding of the 21st Veterinary Association
Malaysia Congress, pp. 97-99. Port Dickson, N. Sembilan; 7-9 Aug 2009
13. G.H. Ong, M. Maizan, S.H. Sharifah, D. Azizah, M.N. Suriani and O. Abdul Rahman
(2009). Development of inactivated H5N2 vaccine against H5N1 influenza virus. Proceeding
of the 21st Veterinary Association Malaysia Congress, Port Dickson, N. Sembilan; 7-9 Aug;
pp 108-110.
14. M. Mohamed and R.M. Elliott (2007). Analyses of the S segments of divergent
orthobunyaviruses. xiii International Conference on negative strand viruses, Salamanca,
Spain; June 17th-22nd
15. M.Maizan, M.N. Norhani, G.H. Ong and S. Syamsiah. (2009). Characterisation of
influenza A virus isolated from swine in Malaysia Proceedings of the 21st Veterinary
Association Malaysia Congress, Port Dickson, Negeri Sembilan: 7-9th August; pp. 97-99
16. G.H. Ong, M. Maizan, S.H. Sharifah, D. Azizah, M.N. Suriani and O. Abdul Rahman
(2009). Development of inactivated H5N2 vaccine against H5N1 influenza virus.
Proceedings of the 21st Veterinary Association Malaysia Congress, 7-9 th august, Port
Dickson, Negeri Sembilan. pp. 108-110
17. M.A. Khairul, M. Maizan, G.H. Ong, S. Syamsiah and A. Siti-Suri (2009). A
preliminary study of efficacy of disinfectant against avian influenza virus. Proceedings of the
21st Veterinary Association Malaysia Congress, 7-9th August, Port Dickson, Negeri
Sembilan. pp. 267-268
d). Sequence Submission to GenBank
Characterization of Nipah Virus from Naturally Infected Pteropus
vampyrus Bats, Malaysia (Accession no. FN869553)
Influenza A virus (A/swine/Malaysia/3966/1984(H1N1), segment 4 Hemagglutinin, segment
5 (Nucleoprotein) and segment 6 neuraminidase (NA) gene, partial cds. (Accession no.
GU433023, GU433024 & HQ283280)