Program Director/Principal Investigator (Last, First, Middle):
Kunkel, David, Charles
BIOGRAPHICAL SKETCH
Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
POSITION TITLE
Kunkel, David Charles
Assistant Professor
eRA COMMONS USER NAME (credential, e.g., agency login)
dckunkel
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and
residency training if applicable.)
DEGREE
INSTITUTION AND LOCATION
MM/YY
FIELD OF STUDY
(if applicable)
University of New Mexico, Albuquerque, NM
B.S.
05/03
Biology
University of New Mexico School of Medicine,
Albuquerque, NM
M.D.
05/08
Medicine
Internship &
Residency
06/08-06/11
Internal Medicine
Fellowship
07/11-06/14
Gastroenterology
Cedars-Sinai Internal Medicine Residency
Training Program, Los Angeles, CA
UCLA Training Program in Digestive Diseases,
Los Angeles, CA
A. Personal Statement
My area of research and specialized training is in GI motility and physiology, including
electrogastrography, gastric emptying, high-resolution esophageal manometry, pH tests, breath
testing, impedance, the wireless motility capsule (SmartPill), anorectal manometry, and biofeedback
therapy. I received training in GI motility at UCLA and Cedars-Sinai during residency and fellowship.
My past mentors include both the current president and immediate past-president of the American
Neurogastroenterology & Motility Society (ANMS), Drs. Lin Chang and Satish Rao, and also Drs. Jeff
Conklin and Mark Pimentel. I was a recipient of the ANMS Clinical Training Award in motility in 2013,
which I used towards obtaining specialized training in gastric and anorectal motility from Dr. Satish
Rao at Georgia Regents University. I presented research on the relationship between methane and
gastric motor function at the ANMS annual meeting in 2013. I have also published several high
impact studies in the field of GI motility, including on post-infectious IBS, methane production in
constipation, and use of a GLP-1 agonist for treatment of short bowel syndrome. I currently assist Dr.
Ravi Mittal in directing the GI Motility and Physiology Center at UC San Diego.
B. Positions and Honors
Positions
06/2008-06/2011 Intern & Resident, Cedars-Sinai IM Residency Training Program, Los Angeles, CA
06/2011-06/2014 Fellow, UCLA Training Program in Digestive Diseases, Los Angeles, CA
09/2014-Present Assistant Professor of Clinical Medicine, UC San Diego, La Jolla, CA
Honors (selected)
2002
Phi Beta Kappa Honor Society
2002
Golden Key National Honor Society
2002
Phi Kappa Phi Honor Society
2003
American Chemical Society Student Recognition Award (top student studying chemistry)
OMB No. 0925-0001/0002 (Rev. 08/12 Approved Through 8/31/2015) Page
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Biographical Sketch Format Page
Program Director/Principal Investigator (Last, First, Middle):
2003
2003-2004
2008
2009
2010
2010
2011
2012
2013
Kunkel, David, Charles
Summa cum laude, B.S. in Biology with minor in Chemistry, University of New Mexico
NIH Intramural Research Training Award, Bethesda, MD
Competitive travel grant recipient, UNM School of Medicine
American College of Gastroenterology
The Laurence Seigler Award ($2,500 research prize)
American Gastroenterological Association
American Society for Gastrointestinal Endoscopy
American Neurogastroenterology and Motility Society
ANMS Clinical Training Award in Motility ($2,000 award to train under Dr. Satish Rao)
C. Selected Peer-reviewed Publications (Selected from 39 peer-reviewed publications)
1. El-Serag HB, Sonnenberg A, Jamal MM, Kunkel D, Crooks L, Feddersen RM. Characteristics of intestinal
metaplasia in the gastric cardia. Am J Gastroenterol. 1999 Mar;94(3):622-7. PMID: 10086641.
2. Gebert C, Kunkel D, Grinberg A, Pfeifer K. H19 imprinting control region methylation requires an imprinted
environment only in the male germ line. Mol Cell Biol. 2010 Mar;30(5):1108-15. PMID: 20038532.
3. Kunkel D, Basseri RJ, Makhani MD, Chong K, Chang C, Pimentel M. Methane on Breath Testing Is
Associated with Constipation: A Systematic Review and Meta-analysis. Dig Dis Sci. 2011 Jun;56(6):1612-8.
PMID: 21286935.
4. Basseri RJ, Kunkel D, Low K, Conklin JL, Pimentel M. Importance of Diarrhea in Evaluating Constipation in
Irritable Bowel Syndrome Clinical Studies. J Clin Gastroenterol. 2011 Oct;45(9):790-3. PMID: 21301356.
5. Morales W, Pimentel M, Hwang L, Kunkel D, Pokkunuri V, Basseri B, Low K, Wang H, Conklin JL, Chang
C. Acute and chronic histological changes of the small bowel secondary to C. jejuni infection in a rat model for
post-infectious IBS. Dig Dis Sci. 2011 Sep;56(9):2575-84. PMID: 21409374.
6. Kunkel D, Basseri B, Low K, Lezcano S, Soffer EE, Conklin JL, Mathur R, Pimentel M. Efficacy of the
glucagon-like peptide-1 agonist exenatide in the treatment of short bowel syndrome. Neurogastroenterol Motil.
2011 Aug;23(8):739-45. PMID: 21557790.
7. Tan C, Kunkel D, Ocampo LH, Sanmiguel CP, Karsan S, Cohen H, Leung FW. A novel application of the
water exchange method in the treatment of sigmoid volvulus: a report of two cases. J Interv Gastroenterol.
2013 Jan;3(1):28-30. PMID: 24147224.
8. Ocampo LH, Kunkel D, Yen A, Tan CR, Leung JW, Leung FW. Underwater hot and cold snare polypectomy
can be safely executed during water exchange colonoscopy. J Interv Gastroenterol. 2013 Jul;3(3):104-106.
PMID: 24478929.
9. Huang BL, Kunkel D, So LY, Conklin JL. Using a stent extractor for a case of pill impaction: a novel
approach. Gastrointest Endosc. 2014 Jan;79(1):185-6. PMID: 24342600.
10. Jamil LH, Huang BL, Kunkel D, Jayaraman V, Soffer EE. Successful gastric volvulus reduction and
gastropexy using a dual endoscope technique. Case Rep Med. 2014;2014:136381. PMID: 24563653.
OMB No. 0925-0001/0002 (Rev. 08/12 Approved Through 8/31/2015)
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Biographical Sketch Format Page