Study Guide – Chapter 5 – Chromosome Mapping in Eukaryotes
1. Genetic linkage
2. Parental (noncrossover) gametes
3. Recombinant (crossover) gametes
4. Interlocus distance
5. Linkage ratio
6. Linkage group
7. Correlation between recombination events and gene distance on chromosome
8. Thomas H. Morgan
9. Alfred H. Sturtevant
10. Chiasma (singular) Chiasmata (plural)
11. How to figure out map distance by recombination frequencies
12. Map units
13. Single crossover events (what that can tell us about 2 genes – distance)
14. Double crossover events (what that can tell us about multiple genes – distance and
sequence)
15. Frequency of DCO events compared to SCO events
16. Requirements for three-point mapping (3 factors)
17. How to figure out gene distance in SCO events
18. How to figure out gene distance and sequence in DCO events
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19. Noncrossover F2 phenotypes
20. Double-crossover phenotypes
21. Reciprocal classes
22. Methods I and II for determining gene sequence from a DCO event
23. Know how to determine the coefficient of coincidence ©
24. Know how to determine interference
25. Mapping accuracy in closely linked genes vs genes far apart
26. LOD score analysis
27. Somatic cell hybridization
28. Heterokaryon
29. Synkaryon
30. Synteny testing
31. DNA markers
32. RFLPs
33. Microsatellites
34. SNPs
35. Examples of crossover events during mitosis
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