Genomic Disorders
The Genomic Basis of Disease
Lupski, James R.; Stankiewicz, Pawel T. (Eds.)
2006, 448 p. 112 illus., 1 in color., Hardcover
ISBN: 978-1-58829-559-0
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109,95 €
About this book
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Table of contents
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About this book
A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the
structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural
features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated
with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders
in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus
undergoing rearrangement, their clinical features, and frequency of detection.
Written for:
Genome and clinical researchers working in the fields of genetics, medical genetics, human genetics, genetic counseling,
mouse genetics, and cytogenetics