GHECon affiliate profile
Kirsten Bibbins-Domingo, August 5, 2013
Name
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Narrative
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detailed
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publications
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projects
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Kirsten Bibbins-Domingo, PhD, MD, MAS
Department of Medicine and of Epidemiology and Biostatistics, UCSF Center for
Vulnerable Populations, K scholars Program in the Clinical and Translational Sciences
Institute
Dr. Bibbins-Domingo’s work focuses on understanding the interaction between social,
behavioral, and biological factors that place vulnerable groups at risk for cardiovascular
disease early in life and population-wide policy level interventions that may prevent
disease in these groups in local, national and international context.
She is a cardiovascular epidemiologist who has published extensively on the
development of heart disease in young adults and race/ethnic and income differences
in manifestations of heart disease in US as well as US subpopulations such as Mexican
Americans. Dr. Bibbins-Domingo’s interests further extend to global prevention efforts
and she has collaborated with investigators in Canada, United Kingdom, China, Mexico,
Argentina, and Chile.
Dr. Bibbins-Domingo leads the team at UCSF working on the Cardiovascular Disease
(CVD) Policy Model, a computer simulation of heart disease in US adults, that has been
used to projected the improved health and cost-savings gained from population-wide
policies aimed at tobacco control, reduced dietary salt, sugar-sweetened beverage
consumption reduction, and statin use in the US and several international countries,
specifically United Kingdom, China, Mexico, Argentina, and Chile.
Dr. Bibbins-Domingo has provided recommendations to local, state, federal, and
international organizations interested in the impact on food and nutrition policies on
cardiovascular disease prevention and health disparities, including the California
Department of Public Health, the Centers for Disease Control and Prevention (CDC).
Most notably, she currently serves as a scientific consultant and is a member of the Pan
American Health Organization (PAHO) at the World Health Organization (WHO).
She has served on several committees of the Institute of Medicine (IOM), advising
federal agencies on policies related to adverse effects of vaccines, presumptive
disability in veterans, valuing community-based prevention, and evaluating the impact
of population-wide sodium reduction. She is a member of the US Preventive Services
Task Force that develops national guidelines for clinical prevention.
 Extend user-friendly locally-adapted intervention CVD Policy Model to multiple
diseases and countries
 Expand mentorship efforts to develop leaders in the range of disciplines necessary
for the study of CVD disparities
Local/National:
 “Comparative effectiveness Analysis of Treat-to-Target and Risk Based Blood
Pressure Control Policy.” (NIH-NHLBI, 8/19/11-6/30/14) Goal: To assess the
effectiveness of US national blood pressure control policy, compare current guidelines
to alternative risk or age-based approaches, and estimate guideline effectiveness in the
face of future demographic shifts in the US
 “Addressing Disparities in Chronic Disease with Teen and Young Adult Focus.”
(Comprehensive Centers of Excellence - NIMHD 10/1/12-9/30/17) Goal: To Center for
Health And Risk in Minority youth and adults (CHARM), a new comprehensive center of
excellence that will address racial and ethnic disparities in chronic disease through a
focus on minority children, adolescents, and young adults (ages 8-35 years, hereafter,
“youth and young adults”).
 “Discovery and Healthcare Innovation to Address Disparities in Stroke (DIADS) – A
Kaiser Permanente Northern California (KPNC) and University of California, San
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Collaborators
(Selected)
5 key
publications
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Teaching
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Substantive
areas
Francisco (UCSF) Collaborative Center.” (NINDS, 9/30/12-8/31/17) Goal: To create a
regional collaborative center to study the causes of disparities in stroke and design and
test interventions aimed at addressing these disparities. Role: Multiple PI with Stephen
Sidney.
International:
 UC MEXUS-CONACYT, 7/1/11 – 12/31/13. Goal: To develop a Mexican version of the
Coronary Heart Disease (CHD) Policy Model and create both a useful tool for the
evaluation of clinical and public health interventions in Mexico.
 “Comparative effectiveness of policies to reduce dietary salt intake in the Pacific
Rim.” (UC Pacific Rim Research Program, 7/1/12-6/30/14) Goal: To adapt the CHD Policy
Model to Argentina, China, and Chile to evaluate the anticipated effectiveness and cost
effectiveness of the country-specific national sodium reduction interventions.
 “Enhancing Mexican capacity for CVD policy research.” (NIH- Fogarty International
Center, 3/20/13-3/31/16) Goal: To collaborate with the Instituto Nacional de Salud
Publica, Cuernavaca, and to create capacity within Mexico to use the Model to conduct
Mexico and global comparative policy oriented research. Role: Multiple PI with
Fernandez, A.
 Economists & modelers: Lightwood J (UCSF), Moran A (Columbia), Wang YC
(Columbia), Goldman L (Columbia), Odden M (Oregon),
 Mathematician: Coxson P (UCSF)
 Clinical & epidemiology researchers: Pletcher M (UCSF)
 International: Campbell N (Canada) Barquera S (Mexico), Ferrante D (Argentina),
Mejia R (Argentina), Zhao D (China), Sanchez H (Chile), and Albala C (Chile)
 Bibbins-Domingo K, Coxson P, Pletcher M, Lightwood J, Goldman L. Adolescent
overweight and future adult coronary heart disease. N Eng J Med
2007;357(23):2371-9.
 Bibbins-Domingo K, Chertow GM, Coxson PG, Moran AE, Lightwood JM, Pletcher MJ,
Goldman L. Population reductions in Coronary Heart Disease and Stroke associated
with modest reductions in salt intake. N Eng J Med, 2010;362 (7):590-9.
[PMC3066566]
 Moran A, Gu D, Zhao D, Coxson P, Wang YC, Chen C, Liu J, Cheng J, Bibbins-Domingo
K, He J, Goldman L. Future cardiovascular disease in China: Markov model and risk
factor scenario projections from the Coronary Heart Disease Policy Model-China.
Circulation: Cardiovascular Quality and Outcomes, 2010;(3):243-52. [PMC2937540]
 Millett C, Laverty AA, Stylianou N, Bibbins-Domingo K, Pape UJ. Impacts of a national
strategy to reduce population salt intake in England: serial cross sectional study. PLoS
One 2012;7(1):e29836. [PMC3251604]
 Konfino J, Mekonnen TA, Coxson PG, Mejia R, Ferrante D, Bibbins-Domingo K.
Projected impact of a sodium consumption reduction initiative in Argentina: An
analysis from the CVD Policy Model-Argentina. PLOS ONE 2013. In Press.
 “Designing Clinical Research” course at local, national and international level
 Master Seminar in the Masters in Clinical Research Program at CTSI
 K Scholars Program at CTSI
 Mentoring
Established: CVD intervention and disease modeling, cost-effectiveness, health
disparities, mentorship
Established: Cardiovascular disease, heart failure, health disparities, epidemiology,
cardiovascular risk factors in young adults, cystatin C, b-type natriuretic peptide,
medication adherence, obesity, chronic kidney disease, sodium, salt, hypertension
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