Cellular Neuroscience (NB&B 207) - Winter 2015
M,W,F 10:30 – 11:50 : 2246 McGaugh Hall
Instructors – Ian Parker (course coordinator) iparker@uci.edu, Raju Metherate rmethera@uci.edu,
Katumi Sumikawa ksumikaw@uci.edu
Grading Policy: Grades will be based on exams and take-home quizzes
Text: There is no assigned text. Handouts and readings will be assigned during lectures. Purves et al.
"Neuroscience" can be used for introductory material. The 2nd edition is available free at
http://www.ncbi.nlm.nih.gov/books/NBK11103/
Date
Topic
Instructor
Section #1 Ion channels and neuronal electrophysiology
Jan 5
Jan 7
Jan 9
Jan 12
Jan 14
Jan 16
Jan 19
Jan 21
Jan 23
Jan 26
Jan 28
Introduction to electrical concepts
Passive electrical properties of membranes
Membrane potential, Nernst, Goldman equations
Ion channels – electrophysiology, patch clamping
Ion channels – voltage-gated channels
Ion channels – ligand-gated channels
Martin Luther King Holiday
Action potentials
The Hodgkin & Huxley Axon
Discussion/review session
EXAM #1
Section 2 # Synaptic transmission
IP
IP
IP
IP
IP
IP
Jan 30
Feb 2
Feb 4
Feb 6
Feb 9
Feb 11
Feb 13
Feb 16
Feb 18
Feb 20
Feb 23
Feb 25
Feb 27
Chemical synapses, quantal transmission
Ca2+ and neurotransmitter release, EPSPs and IPSPs
Slow synaptic potentials
Synaptic integration
Neurotransmitters
Molecular mechanisms of vesicular release
Neurotransmitter receptors
President's Day Holiday
Second messenger pathways #1
Second messenger pathways #2
Synaptic plasticity
Discussion/review
EXAM #2 (during lecture period – before lab class)
RM
RM
RM
RM
KS
KS
KS
RM
RM
IP/RM
KS
KS
KS
KS/RM
Cellular Neuroscience Lab (207L)
March 2–March 13 Lab class – full time every day
March 13 Student presentations for lab class
I.P. / R.M.