Program Director/Principal Investigator (Quinones-Hinojosa, Alfredo):
BIOGRAPHICAL SKETCH
Provide the following information for the Senior/key personnel and other significant contributors in the order listed on Form Page 2.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
POSITION TITLE
Nestoras Mathioudakis
Postdoctoral Fellow in Endocrinology
eRA COMMONS USER NAME (credential, e.g., agency login)
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and
residency training if applicable.)
DEGREE
INSTITUTION AND LOCATION
MM/YY
FIELD OF STUDY
(if applicable)
Johns Hopkins University
Johns Hopkins School of Medicine
Johns Hopkins Bayview Medical Center
Johns Hopkins Hospital
BA
MD
05/97
05/01
06/09
French
Medicine
Internal Medicine
Endocrinology
NOTE: The Biographical Sketch may not exceed four pages. Follow the formats
and instructions below.
A.
Personal Statement
I am a Postdoctoral Fellow in the Division of Endocrinology and Metabolism at the Johns
Hopkins University School of Medicine. I am board-certified in endocrinology and metabolism
and internal medicine. Clinically, I care for patients with a broad range of endocrine
conditions, ranging from diabetes mellitus, to less common endocrine disorders, such as
pituitary tumors. My research focus, sponsored by an NIH T32 research training grant, is on
understanding the development of pituitary tumors. I am exploring the role that adult pituitary
stem cells may play in the development of pituitary tumors. In addition, I am currently
involved in a clinical study to determine the prevalence of anterior pituitary dysfunction in
individuals with Normal Pressure Hydrocephalus.
B.
Positions and Honors
Phi Beta Kappa, elected junior year of undergraduate (top 1% of class GPA)
First place, oral clinical vignette, Maryland Mulholland-Mohler Associates
C.
Selected Peer-reviewed Publications
1. Wu S, Powell J, Mathioudakis N, Kane S, Fernandez E, Sears CL. Bacteroides
fragilis enterotoxin induces intestinal epithelial cell secretion of interleukin-8 through
mitogen-activated protein kinases and a tyrosine kinase-regulated nuclear factorkappaB
pathway. Infect Immun. 2004 Oct;72(10):5832-9.
2. Mathioudakis N, Salvatori R. Adult-onset growth hormone deficiency: causes,
complications and treatment options. Curr Opin Endocrinol Diabetes Obes. 2008
Aug;15(4):352-8.
3. Mathioudakis N, Salvatori R. Pituitary tumors. Curr Treat Options Neurol. 2009
Jul;11(4):287-96.
4. Mathioudakis N, Ball D. Acromegaly. The Johns Hopkins Diabetes Guide POC-IT
Center (Johns Hopkins Point of Care Information Technology Center), Baltimore,
MD. September 2010
PHS 398/2590 (Rev. 06/09)
Page
Biographical Sketch Format Page
Program Director/Principal Investigator (Quinones-Hinojosa, Alfredo):
Nestoras N. Mathioudakis, M.D. Curriculum Vitae, page 2, Dec. 7, 2011
5. Mathioudakis N, Ball D. Glucagonoma. The Johns Hopkins Diabetes Guide POCIT
Center (Johns Hopkins Point of Care Information Technology Center), Baltimore,
MD. June 2010
6. Pendleton C, Adams H, Mathioudakis N, Quinones-Hinojosa, A. “Sellar Door:
Harvey Cushing’s Entry into the Pituitary Gland, the Unabridged Hopkins Experience
1896-1912.” World Neurosurg 2011 Nov 10.
7. Pendleton C, Mathioudakis N, Salvatori R, Quinones-Hinojosa A. "Glandular
intoxication" following emergent tracheotomy during transsphenoidal surgery for
acromegaly: Cushing's 1910 unrecognized case of thyroid storm? Pituitary. 2011
Mar 11.
8. Xing JC, Bishop JA, Mathioudakis N, Agrawal N, Tufano RP. “A large
nonmetastatic anaplastic thyroid cancer with complete thyroidal confinement.” Case
Report Med. 2011;2011:583978.
9. Mathioudakis N, Pendleton C, Quinones-Hinojosa A, Wand G, and Salvatori R,
“ACTH-Secreting Pituitary Adenomas: Size Does Not Correlate With Hormonal
Activity,” Pituitary, November 2011.
10. Mathioudakis N, Salvatori R. Medical therapy of hormone-secreting pituitary
adenomas. In Schmidek & Sweet’s Operative Neurosurgical Techniques: Indications,
Methods, and Results, A Quinones-Hinjosa editor, 2012 in press
11. Mathioudakis N, Salvatori R. Management Options for Persistent Postoperative
Acromegaly. In Neurosurgery Clinics of North America, Ed. Aghi and Blevins.
(submitted; invited review)
D.
Research Support
1. NIH T32 molecular training grant: basic-science research on pituitary tumors in the lab of
Alfredo Quinones-Hinojosa, M.D.
2. Pfizer Research Support: Anterior Pituitary Function in individuals with normal pressure
hydrocephalus.
PHS 398/2590 (Rev. 06/09)
Page
Biographical Sketch Format Page