attachment a

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2015

ATTACHMENT A - PART 1

ANESTHESIA AND SURGERY

For administration of any general anesthetics or performing surgical procedures on animals.

ANESTHESIA

- List ALL anesthetics used for each species.

Include tranquillizers and induction agents if applicable.

DRUG NAME SPECIES Dose Route

Neuromuscular Blocker

Will any neuromuscular blocking agents (eg. succinylcholine, gallamine) be administered? YES

Volume

NO

Drug Name: Species:

Dose: Route: Volume:

What special precautions are taken to ensure that animals remain fully anesthetized while neuromuscular blockers are in effect?

Who will perform and monitor anesthesia?

How will depth of anesthesia be monitored?

Will animals be mechanically ventilated? YES NO

What is the maximum number of times a single animal will be anesthetized and allowed to recover?

What is the estimated duration of surgery, from induction of anesthesia until completion of the procedure?

SURGERY

- Describe each surgical procedure, including details such as the location and size of incision, placement of implants or monitoring/recording devices, wound closure. (this answer section will expand)

Is this a survival surgery (ie. animals are expected to wake up at the end of the procedure)?

YES NO

If YES, please complete ATTACHMENT A - PART 2

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2015

ATTACHMENT A - PART 2

ANESTHESIA AND SURGERY

c. d.

ASEPTIC TECHNIQUE

-

The use of aseptic technique is required for all survival surgeries.

a. b.

Who will be performing the surgery?

Where will the surgery be performed? Note that CCAC requires all survival surgeries to be performed within the animal facility.

How will surgical instruments be sterilized?

What antiseptic is used to disinfect the animal’s skin?

SURGICAL RECOVERY

a. b.

What is the maximum number of survival surgeries a single animal will undergo?

If more than one survival surgery is planned, what is the length of time between surgeries and why is more than one surgery necessary?

c. d.

How long will animals be maintained after the final surgery?

Describe the short-term (up to 48 hours) and long-term effects of the surgery.

(For example, some surgeries might be expected to cause a decrease in appetite that would resolve within a day or two. Other surgeries might produce permanent deficits such as hind limb paralysis.)

(this answer section will expand) a. b. c. e. What unexpected complications could occur as a result of the surgical procedure(s)?

POST-OPERATIVE CARE

Describe the post-operative care, including provision of warmth, fluids, antibiotics, etc

Where will animals be held during recovery period, and for how long?

If animals are held outside of the animal facility for more than 12 hours, please fully justify to the UCLA:

ANALGESIA

- The use of analgesics is expected after all survival surgical procedures.

a. Will analgesics be administered? YES NO

If NO, provide scientific justification for withholding analgesics. Include references if applicable.

(this answer section will expand): b. Who will administer analgesics?

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2015

List all Analgesics:

Drug Name Species Dose Route Frequency of

Administration

MONITORING -

It is expected that all animals will be carefully monitored after surgery, and that records will be maintained for each animal or group of animals.

a. b.

How often and for how long are animals monitored after surgery?

Who will do the monitoring?

c. What critical signs will be assessed?

For MAJOR surgical procedures

a recovery record must be prepared for each animal to document provision of appropriate care. The record must be available in the animal housing room for veterinary inspection. For most surgeries the record will be required only for the first 24-48 hours and can be a simple checklist attached to the cage card. In other cases, particularly where the surgery produces permanent disability (eg. spinal cord injury), a record of care must be maintained for the life of the animal.

Please prepare a recovery record sheet suitable for your specific project and submit it along with your protocol application.

(Attach as a separate sheet)

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