Name and surname: Řípová Daniela, RNDr., CSc.
Date of birth: 28. 8. 1953
Graduate studies:
1977 Graduated from the Faculty of Sciences, Dept. of General Physiology, Charles University,
Prague
1986
RNDr. - Faculty of Sciences, Charles University, Prague
1987
awarded a postdoctoral CSc. Degree (Ph.D.)- Faculty of Sciences, Charles University, Prague
1977-1986
postgraduate study, Department of Physiology and Developmental Biology, Faculty of
Science, Charles University, Prague. (Phospholipid and phosphoinositide turnover in platelets of
manio-depressive patients.)
Position held:
1986-1989
Psychiatric Research Unit, 1st Faculty of Medicine, Charles University Prague.
(Research in the field of binding tricyclic antidepressants to phospholipids.)
1989-1991
Senior researcher at the Research Institute for Pharmacy and Biochemistry, Prague.
(Research area: monoamine and their metabolites determination and various receptor binding
assays- by using these methods the effects of different CNS drugs were studied.)
1991- 2000
Head of the Laboratory of Biochemistry, Prague Psychiatric Center. (Since 1992 –
study of phospholipids and phosphoinositide second messenger system in schizophrenia. Since 1995
– study of abnormalities in the composition of phospholipids and fatty acids in different areas of
postmortem brains in Alzheimer´s disease (AD) and the effect of aging on this important membrane
components. Since 1998- searching for biomarkers of early and middle stages of AD.)
Since 1992
Scientific secretary of Prague Psychiatric Center
Since 2007
Head of the Laboratory of Biochemistry and Brain Pathophysiology and AD center
(was transformed to National Institute of Mental Health)
Since 2015
Head of the Department Research of Neurobiology of Ageing, Drug Dependence and
Severe Mental Disorders of National Institute of Mental Health
Memberships:
International Brain Research Organization, European College of Neuropsychopharmacology,
European Neuroscience Association, Federation of European Biochemical Sciences, International
Union of Biochemical Sciences, International Union of Physiological Sciences, Czech Society for
Biochemistry and Molecular Biology, Medical Society of J.E. Purkyně, Czech
Neuropsychopharmacological Society, Society of Biological Psychiatry, Czech Society of Psychiatry
Awards and honors:
2004 a 2005: two 1st prices of Academia Medica Pragensis sponsored by Novartis (the best papers of
the years 2003 and 2004 in the field of Alzheimerś dementia diagnosis and treatment)
2008 The Award for the best poster presentation of A.Bartos, P.Zach, I.Ibrahim, D.Ripova : Visual
rating and volumetry of hippocampus on magnetic resonance imaging in Alzheimer disease, 16th
European Congress of Psychiatry, AEP Nice, April 5-9.
2014 The Award of Czech Endocrine Society in the category of best publication in the journal author,
regardless of age for work Bičíková M, Hill M, Řípová D, Mohr P, Hampl R. Determination of steroid
metabolome as a possible tool for laboratory diagnosis of schizophrenia. Journal of Steroid
Biochemistry and Molecular Biology, 2013, roč. 133, č. 1, s. 77-83.
The best poster award of the chair of the Chromatography and Electrophoresis Group of the Czech
Chemical Society at the 20th International Symposium of Separation Sciences 2014 in Prague for
Barbora Jankovičová, Zuzana Svobodová, Lenka Hromádková, Rudolf Kupčík, Daniela Řípová, Zuzana
Bílková: Benefits of immunomagnetic separation for epitope identification in clinically important
protein antigens
2015 Special award from dean of Third Faculty of Medicine in Prague on Student conference of Third
Faculty of Medicine in Prague for poster presentation Michala Kolářová, Lenka Hromádková, Barbora
Jankovičová, Aleš Bartoš, Jan Říčný, Zuzana Bílková, Daniela Řípová: Naturally occurring antibodies
against protein associated with Alzheimer disease.
Points of interest:
Biochemist, special interest in the research of Alzheimer disease and schizophrenia, principal
investigator and co-investigator of many projects associated with Alzheimer disease
Grants awarded:

IGA MH CR No. IZ866 "The role of phospholipids and phosphoinositide - signalling system in
schizophrenia", 1992-1994

IGA MH CR No. IZ2877 "Changes in lipid composition of brain in Alzheimer s disease", 19951997

IGA MH CR No.NG15 „Biomarkers of Alzheimer´s disease“, 1998-2000

MEYS: PG96185 "Changes in the composition of neuronal membranes and in regulation of
choline transport in brains od senile dementia subjects"- 1996

MEYS: PG97216 "Presentation of results of the project "Changes in lipid composition of brain
in Alzheimer s disease"- 1997

MH CR: MZ00000023752 „Identification of sources of psychiatric morbidity, and increasing of
effectivity of the preventive and therapeutical methods in mental helth care in the Czech
Republic“, 1999-2004 (subproject „Neurodegenerative diseases and schizophrenia course
markers for improving the diagnosis“ – 2001-2004)

MH CR: MZ0PCP2005 „Study of sources of psychiatric morbidity, and increasing the
effectiveness of the preventive and therapeutical methods in mental helth care in the Czech
Republic 2005-20011“ (subprojects: „Amyloid beta peptides in Alzheimer´s dementia“ and
„Biological markers of Alzheimer´s dementia“ – 2005-2011)

MEYS: 1M0517 „Center of neuropsychiatric studies 2005-2011 (Neurobiology in clinical
application), (subproject „Application and testing of models of the cognitive activities of a rat
in models of Alzheimer´s disease and other neuropsychiatric disorders - neurochemical
testing of their valididy“ – 2005-2011)

AS CR: KAN200520701 „Nano-PCR – ultrasensitive test for detection of specific proteins in
body fluids“ – 2007-2011

IGA MH CR: NS 9835 „The role of neuroactive steroids and other hormonal parameters in
diagnostics and treatment of schizophrenia“ – 2008-2011

GA CR. GAP303/11/1907 „Novel inhibitors of acetylcholinesterase derived from 7-MEOTA potential Alzheimer´s disease drugs“ – 2011-2015

GA CR. P304/12/G069 „Project of excellence in the field of neuroscience“ – 2012-2018

IGA MH CR: NT13890 „The role of neuroactive steroids in etiopathogenesis of mood and
anxiety disorders“ – 2012 – 2015

MEYS: LH13254 PCP-IZRAEL „Effects of low dietary levels of advanced glycation on memory
and Alzheimer's neuropathology“ – 2013 - 2015