Curriculum Vitae
Jean-Christophe Corvol, Born in 1971, August 5th, French, marital life
Address: CIC Neuro, bâtiment ICM, Hôpital Pitié-Salpêtrière, 47/83 Bd de l’Hôpital, 75013 Paris, France
Tel: +33 1 42 16 57 66. Fax: +33 1 42 16 57 67, jean-christophe.corvol@psl.aphp.fr
Neurologist, Pharmacologist, CNOM #: 75/69402, ADELI #: 751694027, RPPS #: 10001556389
Current position
2010 Associate coordinator of the French CIC Neurosciences Network (NS-Park)
2008 Coordinator of the Clinical Neurosciences Research Center (CIC-9503), Pitié-Salpêtrière Hospital
2008 PI, team 1 (Pr Brice), CR-ICM, UPMC, INSERM UMRS-975, CNRS UMR7225, Pitié-Salpêtrière Hospital
2007 Assistant Professor (MCU-PH), Department of Pharmacology, Pitié-Salpêtrière Hospital
Education
2009
Research Habilitation, University Paris VI (UPMC)
2005
PhD, University Paris VI (UPMC)
2003
MD, Neurology, University Paris VI (UPMC)
2000
Master in molecular and cellular pharmacology, University Paris VI (UPMC)
Past positions and training
2006-2007
Post-doctoral position, Molecular Neurogenetic Laboratory, UCSF, San Francisco, USA
2005-2006
Clinical Assistant, Department of Pharmacology, Pitié-Salpêtrière hospital
2003-2005
Clinical Assistant, Department of Neurology, Pitié-Salpêtrière hospital
2001-2003
PhD training, INSERM U536, JA Girault, Institut du fer à moulin, Paris.
1999-2000
Master training, INSERM U114, J. Glowinski, Collège de France, Paris.
1995-2001
Residency in Neurology, Paris
Clinical research
GCP
Web-based training course “Protecting Human Research Participants” (NIH). 2011
Coordination of clinical research studies:
- Predictive factor of DBS response in PD (PREDISTIM). Physiopathology, multicenter, national. APHP. PI. 2013-2016.
- Amantadine and L-dopa induced dyskinesia. Phase II, multicenter, national. CHU Toulouse. NCT01538329. PI for site. 2012-15
- AQW051 in L-dopa Induced Dyskinesia. Phase II, multicenter, international. Novartis. NCT01474421. PI for site. 2012-2013
- Behavioral Addiction and Genes in PD (BADGE-PD). Physiopathology, multicenter, national. APHP. PI. 2011-2013.
- Drug Interaction with Genes in PD (DIGPD). Physiopathology, multicenter, national. APHP. NCT01564992. PI. 2009-2014.
- ADX48621 in L-dopa Induced Dyskinesia. Phase II, multicenter, international. Addex. NCT01336088. PI for site. 2011-2012
- Davunetide in PSP. Phase II, multicenter, international. Allon Therapeutics. NCT01110720. PI for France. 2011-2012
- Blood brain barrier in Parkinson Plus Syndroms. Physiopathology, multicenter, national. APHP. PI for site. 2006-2012
- IPX066 In Advanced PD. Phase III, multicenter, international. IMPAX. NCT00974974. . PI for France. 2009-2010
- COMT polymorphism and entacapone efficacy in PD. Phase IV, monocenter. NCT00373087. APHP. PI. 2007-2009
- Heart valve disease and pergolide in PD. Phase IV, monocenter. SFC. NCT00202657. PI. 2006-2007
Co-Investigator in more than 20 clinical trials and clinical research studies. (since 2003)
Member of scientific societies and boards
- Commission Scientifique Spécialisée n°6 : Neurosciences, Cognition, Santé Mentale (CSS6, INSERM, 2012-)
- Scientific board of the French Parkinson association (2010-)
- Scientific board of the Fédération pour la Recherche sur le Cerveau (FRC) (2010-)
- French Society of Pharmacology (2003-)
- French Society of Neurology (2003-)
- Comité d'orientation stratégique et de suivi des essais cliniques (Cossec, INSERM, 2009-2012)
- Scientific Board of the French College of Pharmacology (2008-2012)
- Advisory board of the European College of Neuropsychopharmacology (2005-2012)
Awards
2011
Prix Association pour le Développement de la Pharmacologie Clinique/Patrice Jaillon
2006
Prix jeune chercheur, Fondation Bettencourt-Schüller
Date : 01 January 2013
Signature :
Page 1 sur 5
Publications (by publication date)
Moreau C, Delval A, Defebvre L, Dujardin K, Duhamel A, Petyt G, Vuillaume I, Corvol JC, Brefel-Courbon C,
Ory-Magne F, Guehl D, Eusebio A, Fraix V, Saulnier PJ, Lagha-Boukbiza O, Durif F, Faighel M, Giordana C,
Drapier S, Maltête D, Tranchant C, Houeto JL, Debû B, Sablonniere B, Azulay JP, Tison F, Rascol O, Vidailhet
M, Destée A, Bloem BR, Bordet R, Devos D; Parkgait-II study group. Methylphenidate for gait hypokinesia and
freezing in patients with Parkinson's disease undergoing subthalamic stimulation: a multicentre, parallel,
randomised, placebo-controlled trial. Lancet Neurol. 2012 Jul;11(7):589-96.
Depienne C, Bouteiller D, Méneret A, Billot S, Groppa S, Klebe S, Charbonnier-Beaupel F, Corvol JC, Saraiva
JP, Brueggemann N, Bhatia K, Cincotta M, Brochard V, Flamand-Roze C, Carpentier W, Meunier S, Marie Y,
Gaussen M, Stevanin G, Wehrle R, Vidailhet M, Klein C, Dusart I, Brice A, Roze E. RAD51 haploinsufficiency
causes congenital mirror movements in humans. Am J Hum Genet. 2012 Feb 10;90(2):301-7.
Keller MF, Saad M, Bras J, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Büchel F, Sharma M, Gibbs JR,
Schulte C, Moskvina V, Durr A, Holmans P, KilarskiLL, Guerreiro R, Hernandez DG, Brice A, Ylikotila P,
Stefánsson H, Majamaa K, Morris HR, Williams N, Gasser T, Heutink P, Wood NW, Hardy J, Martinez M,
Singleton AB, Nalls MA; International Parkinson's Disease Genomics Consortium (IPDGC); Wellcome Trust Case
Control Consortium 2 (WTCCC2)*. Using genome-wide complex trait analysis to quantify 'missing heritability' in
Parkinson's disease. Hum Mol Genet. 2012 Nov 15;21(22):4996-5009.
Holmans P, Moskvina V, Jones L, Sharma M; The International Parkinson's Disease Genomics Consortium
(IPDGC), Vedernikov A, Buchel F, Sadd M, Bras JM, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Gibbs
JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, Stefánsson H, Majamaa K, Gasser T, Heutink P,
Wood NW, Martinez M, Singleton AB, Nalls MA, Hardy J, Morris HR, Williams NM.* A pathway-based analysis
provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum Mol Genet.
2012 Dec 13. [Epub ahead of print]
Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Van Broeckhoven C, Bertram L, Bozi M, Crosiers D,
Clarke C, Facheris M, Farrer M, Garraux G, Gispert S, Auburger G, Vilariño-Güell C, Hadjigeorgiou GM, Hicks
AA, Hattori N, Jeon B, Lesage S, Lill CM, Lin JJ, Lynch T, Lichtner P, Lang AE, Mok V, Jasinska-Myga B, Mellick
GD, Morrison KE, Opala G, Pramstaller PP, Pichler I, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L,
Stockton JD, Satake W, Silburn PA, Theuns J, Tan EK, Toda T, Tomiyama H, Uitti RJ, Wirdefeldt K, Wszolek Z,
Xiromerisiou G, Yueh KC, Zhao Y, Gasser T, Maraganore D, Krüger R; GEO-PD Consortium*. Large-scale
replication and heterogeneity in Parkinson disease genetic loci. Neurology. 2012 Aug 14;79(7):659-67. *Corvol
JC, among 103 collaborators.
Lesage S, Condroyer C, Klebe S, Honoré A, Tison F, Brefel-Courbon C, Dürr A, Brice A; French Parkinson's
Disease Genetics Study Group*. Identification of VPS35 mutations replicated in French families with Parkinson
disease. Neurology. 2012 May 1;78(18):1449-50. *Corvol JC, among 23 collaborators.
Metso TM, Tatlisumak T, Debette S, Dallongeville J, Engelter ST, Lyrer PA, Thijs V, Bersano A, Abboud S, Leys
D, Grond-Ginsbach C, Kloss M, Touzé E, Pezzini A, Metso AJ; CADISP group*. Migraine in cervical artery
dissection and ischemic stroke patients. Neurology. 2012 Apr 17;78(16):1221-8. *Corvol JC, among 14
collaborators.
Rosso C, Corvol JC, Pires C, Crozier S, Attal Y, Jacqueminet S, Deltour S, Multlu G, Leger A, Meresse I, Payan
C, Dormont D, Samson Y. Intensive versus subcutaneous insulin in patients with hyperacute stroke: results from
the randomized INSULINFARCT trial. Stroke. 2012 Sep;43(9):2343-9.
Lesage S, Condroyer C, Klebe S, Lohmann E, Durif F, Damier P, Tison F, Anheim M, Honoré A, Viallet F, Bonnet
AM, Ouvrard-Hernandez AM, Vidailhet M, Durr A, Brice A; French Parkinson's Disease Genetics Study Group*.
EIF4G1 in familial Parkinson's disease: pathogenic mutations or rare benign variants? Neurobiol Aging. 2012
Sep;33(9):2233.e1-2233.e5. *Corvol JC, among 23 collaborators.
Metso AJ, Metso TM, Debette S, Dallongeville J, Lyrer PA, Pezzini A, Lichy C, Kloss M, Brandt T, Touzé E,
Southerland AM, Worrall BB, Abboud S, del Zotto E, Leys D, Engelter S, Grond-Ginsbach C, Tatlisumak T;
CADISP Group*. Gender and cervical artery dissection. Eur J Neurol. 2012 Apr;19(4):594-602. *Corvol JC,
among 14 collaborators.
Engelter ST, Dallongeville J, Kloss M, Metso TM, Leys D, Brandt T, Samson Y, Caso V, Pezzini A, Sessa M,
Beretta S, Debette S, Grond-Ginsbach C, Metso AJ, Thijs V, Lamy C, Medeiros E, Martin JJ, Bersano A,
Tatlisumak T, Touzé E, Lyrer PA; Cervical Artery Dissection and Ischaemic Stroke Patients-Study Group*.
Thrombolysis in cervical artery dissection--data from the Cervical Artery Dissection and Ischaemic Stroke
Patients (CADISP) database. Eur J Neurol. 2012 Sep;19(9):1199-206. *Corvol JC, among 78 collaborators.
Pradat PF, Dubourg O, de Tapia M, di Scala F, Dupuis L, Lenglet T, Bruneteau G, Salachas F, Lacomblez L,
Corvol JC, Demougin P, Primig M, Meininger V, Loeffler JP, Gonzalez de Aguilar JL. Muscle gene expression is
a marker of amyotrophic lateral sclerosis severity. Neurodegener Dis. 2012;9(1):38-52.
Cormier F, Muellner J, Corvol JC. Genetics of impulse control disorders in Parkinson's disease. J Neural
Transm. 2012 Dec 12. [Epub ahead of print]
Page 2 sur 5
Rascol O, Ferreira J, Nègre-Pages L, Perez-Lloret S, Lacomblez L, Galitzky M, Lemarié JC, Corvol JC, Brotchie
JM, Bossi L. A proof-of-concept, randomized, placebo-controlled, multiple cross-overs (n-of-1) study of naftazone
in Parkinson's disease. Fundam Clin Pharmacol. 2012 Aug;26(4):557-64.
Corvol JC. Neuroprevention: A new challenge? Rev Neurol (Paris). 2012 Nov;168(11):796-801.
International Parkinson Disease Genomics Consortium, Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin
UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Stefánsson K, Martinez M, Hardy J,
Heutink P, Brice A, Gasser T, Singleton AB, Wood NW.* Imputation of sequence variants for identification of
genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet. 2011 Feb
19;377(9766):641-9. *Corvol JC, among 126 collaborators.
Ross OA, Soto-Ortolaza AI, Heckman MG, Aasly JO, Abahuni N, Annesi G, Bacon JA, Bardien S, Bozi M, Brice
A, Brighina L, Van Broeckhoven C, Carr J, Chartier-Harlin MC, Dardiotis E, Dickson DW, Diehl NN, Elbaz A,
Ferrarese C, Ferraris A, Fiske B, Gibson JM, Gibson R, Hadjigeorgiou GM, Hattori N, Ioannidis JP, JasinskaMyga B, Jeon BS, Kim YJ, Klein C, Kruger R, Kyratzi E, Lesage S, Lin CH, Lynch T, Maraganore DM, Mellick
GD, Mutez E, Nilsson C, Opala G, Park SS, Puschmann A, Quattrone A, Sharma M, Silburn PA, Sohn YH,
Stefanis L, Tadic V, Theuns J, Tomiyama H, Uitti RJ, Valente EM, van de Loo S, Vassilatis DK, Vilariño-Güell C,
White LR, Wirdefeldt K, Wszolek ZK, Wu RM, Farrer MJ; Genetic Epidemiology Of Parkinson's Disease (GEOPD) Consortium*. Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control
study. Lancet Neurol. 2011 Oct;10(10):898-908. *Corvol JC, among 108 collaborators.
Corvol JC, Bonnet C, Charbonnier-Beaupel F, Bonnet AM, Fiévet MH, Bellanger A, Roze E, Meliksetyan G, Ben
Djebara M, Hartmann A, Lacomblez L, Vrignaud C, Zahr N, Agid Y, Costentin J, Hulot JS, Vidailhet M. The
COMT Val158Met polymorphism affects the response to entacapone in Parkinson's disease: a randomized
crossover clinical trial. Ann Neurol. 2011 Jan;69(1):111-8.
Ros-Bernal F, Hunot S, Herrero MT, Parnadeau S, Corvol JC, Lu L, Alvarez-Fischer D, Carrillo-de Sauvage MA,
Saurini F, Coussieu C, Kinugawa K, Prigent A, Höglinger G, Hamon M, Tronche F, Hirsch EC, Vyas S. Microglial
glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism. Proc
Natl Acad Sci U S A. 2011 Apr 19;108(16):6632-7.
International Parkinson's Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2
(WTCCC2)*. A two-stage meta-analysis identifies several new loci for Parkinson's disease. PLoS Genet. 2011
Jun;7(6):e1002142. *Corvol JC, among 139 collaborators.
Depienne C, Cincotta M, Billot S, Bouteiller D, Groppa S, Brochard V, Flamand C, Hubsch C, Meunier S,
Giovannelli F, Klebe S, Corvol JC, Vidailhet M, Brice A, Roze E. A novel DCC mutation and genetic
heterogeneity in congenital mirror movements. Neurology. 2011 Jan 18;76(3):260-4.
Lesage S, Condroyer C, Hecham N, Anheim M, Belarbi S, Lohman E, Viallet F, Pollak P, Abada M, Dürr A, Tazir
M, Brice A; French Parkinson Disease Genetic Group*. Mutations in the glucocerebrosidase gene confer a risk
for Parkinson disease in North Africa. Neurology. 2011 Jan 18;76(3):301-3. *Corvol JC, among 22 collaborators.
Saad M, Lesage S, Saint-Pierre A, Corvol JC, Zelenika D, Lambert JC, Vidailhet M, Mellick GD, Lohmann E,
Durif F, Pollak P, Damier P, Tison F, Silburn PA, Tzourio C, Forlani S, Loriot MA, Giroud M, Helmer C, Portet F,
Amouyel P, Lathrop M, Elbaz A, Durr A, Martinez M, Brice A; French Parkinson's Disease Genetics Study Group.
Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's
disease in the European population. Hum Mol Genet. 2011 Feb 1;20(3):615-27.
Lesage S, Anheim M, Condroyer C, Pollak P, Durif F, Dupuits C, Viallet F, Lohmann E, Corvol JC, Honoré A,
Rivaud S, Vidailhet M, Dürr A, Brice A; French Parkinson's Disease Genetics Study Group. Large-scale
screening of the Gaucher's disease-related glucocerebrosidase gene in Europeans with Parkinson's disease.
Hum Mol Genet. 2011 Jan 1;20(1):202-10.
Vorspan F, Mallet L, Corvol JC, Pelissolo A, Lépine JP. Treating addictions with deep brain stimulation is
premature but well-controlled clinical trials should be performed. Addiction. 2011 Aug;106(8):1535-6;
Bonnet AM, Jutras MF, Czernecki V, Corvol JC, Vidailhet M. Nonmotor symptoms in Parkinson's disease in
2012: relevant clinical aspects. Parkinsons Dis. 2012;2012:198316.
Schüpbach WM, Corvol JC, Czernecki V, Djebara MB, Golmard JL, Agid Y, Hartmann A. Segmental progression
of early untreated Parkinson's disease: a novel approach to clinical rating. J Neurol Neurosurg Psychiatry. 2010
Jan;81(1):20-5.
Pineau F, Schüpbach M, Corvol JC, Flamand-Rouvière C, Vidailhet M, Roze E. Long-standing paraphilia
induced by dopamine agonists in Parkinson's disease. Mov Disord. 2010 May 15;25(7):963-5.
Dujardin K, Dubois B, Tison F, Durif F, Bourdeix I, Péré JJ, Duhamel A; EXECUTIVE study group*. Parkinson's
disease dementia can be easily detected in routine clinical practice. Mov Disord. 2010 Dec 15;25(16):2769-76.
*Corvol JC, among 48 collaborators.
Soubrier M, Haïk S, Hauw JJ, Corvol JC, Lyon-Caen O, Dougados M. Creutzfeldt-Jakob disease in a patient
treated by etanercept for rheumatoid arthritis (RA): just a coincidence? Joint Bone Spine. 2010 Mar;77(2):174-5.
Page 3 sur 5
Devos D; French DUODOPA Study Group*. Patient profile, indications, efficacy and safety of duodenal levodopa
infusion in advanced Parkinson's disease. Mov Disord. 2009 May 15;24(7):993-1000. *Corvol JC, among 60
collaborators.
Corvol JC, Pelletier D, Henry RG, Caillier SJ, Wang J, Pappas D, Casazza S, Okuda DT, Hauser SL, Oksenberg
JR, Baranzini SE. Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after
the initial neurological event. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11839-44.
Faure C*, Corvol JC*, Toutant M, Valjent E, Hvalby O, Jensen V, El Messari S, Corsi JM, Kadaré G, Girault JA.
Calcineurin is essential for depolarization-induced nuclear translocation and tyrosine phosphorylation of PYK2 in
neurons. J Cell Sci. 2007 Sep 1;120(Pt 17):3034-44. *co-first authors.
Corvol JC, Valjent E, Pascoli V, Robin A, Stipanovich A, Luedtke RR, Belluscio L, Girault JA, Hervé D.
Quantitative changes in Galphaolf protein levels, but not D1 receptor, alter specifically acute responses to
psychostimulants. Neuropsychopharmacology. 2007 May;32(5):1109-21.
Corvol JC, Anzouan-Kacou JB, Fauveau E, Bonnet AM, Lebrun-Vignes B, Girault C, Agid Y, Lechat P, Isnard R,
Lacomblez L. Heart valve regurgitation, pergolide use, and parkinson disease: an observational study and metaanalysis. Arch Neurol. 2007 Dec;64(12):1721-6.
PubMed PMID: 18071034.
IF 2007 = 5.8
Valjent E, Corvol JC, Trzaskos JM, Girault JA, Hervé D. Role of the ERK pathway in psychostimulant-induced
locomotor sensitization. BMC Neurosci. 2006 Mar 2;7:20.
Corvol JC, Girault JA, Hervé D. [Role and regulation of dopamine D1 receptors in the striatum: implications for
the genesis of dyskinesia in Parkinson's disease]. Rev Neurol (Paris). 2006 Jun;162(6-7):691-702. Review.
French.
Valjent E, Pascoli V, Svenningsson P, Paul S, Enslen H, Corvol JC, Stipanovich A, Caboche J, Lombroso PJ,
Nairn AC, Greengard P, Hervé D, Girault JA. Regulation of a protein phosphatase cascade allows convergent
dopamine and glutamate signals to activate ERK in the striatum. Proc Natl Acad Sci U S A. 2005 Jan
11;102(2):491-6.
Brami-Cherrier K, Valjent E, Hervé D, Darragh J, Corvol JC, Pages C, Arthur SJ, Girault JA, Caboche J. Parsing
molecular and behavioral effects of cocaine in mitogen- and stress-activated protein kinase-1-deficient mice. J
Neurosci. 2005 Dec 7;25(49):11444-54.
Corvol JC, Valjent E, Toutant M, Enslen H, Irinopoulou T, Lev S, Hervé D, Girault JA. Depolarization activates
ERK and proline-rich tyrosine kinase 2 (PYK2) independently in different cellular compartments in hippocampal
slices. J Biol Chem. 2005 Jan 7;280(1):660-8.
Pascoli V, Valjent E, Corbillé AG, Corvol JC, Tassin JP, Girault JA, Hervé D. cAMP and extracellular signalregulated kinase signaling in response to d-amphetamine and methylphenidate in the prefrontal cortex in vivo:
role of beta 1-adrenoceptors. Mol Pharmacol. 2005 Aug;68(2):421-9.
Corvol JC, Schüpbach M, Bonnet AM; Centre d'Investigation Clinique et Fédération des Maladies du Système
Nerveux, Hôpital de la Pitié-Salpêtrière, Paris. [Pergolide associated valvulopathy: critical analysis of the
literature and practical recommendations]. Rev Neurol (Paris). 2005 Jul;161(6-7):637-43. French.
Corvol JC, Muriel MP, Valjent E, Féger J, Hanoun N, Girault JA, Hirsch EC, Hervé D. Persistent increase in
olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson
disease. J Neurosci. 2004 Aug 4;24(31):7007-14.
Derkinderen P, Valjent E, Toutant M, Corvol JC, Enslen H, Ledent C, Trzaskos J, Caboche J, Girault JA.
Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus. J Neurosci. 2003 Mar
15;23(6):2371-82.
Corvol JC, Bouzamondo A, Sirol M, Hulot JS, Sanchez P, Lechat P. Differential effects of lipid-lowering
therapies on stroke prevention: a meta-analysis of randomized trials. Arch Intern Med. 2003 Mar 24;163(6):66976.
Kadaré G, Toutant M, Formstecher E, Corvol JC, Carnaud M, Boutterin MC, Girault JA. PIAS1-mediated
sumoylation of focal adhesion kinase activates its autophosphorylation. J Biol Chem. 2003 Nov
28;278(48):47434-40.
Hulot JS, Cucherat M, Charlesworth A, Van Veldhuisen DJ, Corvol JC, Mallet A, Boissel JP, Hampton J, Lechat
P. Planning and monitoring of placebo-controlled survival trials: comparison of the triangular test with usual
interim analyses methods. Br J Clin Pharmacol. 2003 Mar;55(3):299-306.
Corvol JC, Bouzamondo A, Sirol M, Hulot JS, Sanchez P, Lechat P. [Antilipemics and prevention of
cerebrovascular accidents. Meta-analysis]. Therapie. 2003 Jan-Feb;58(1):37-48. French.
Page 4 sur 5
Hervé D, Le Moine C, Corvol JC, Belluscio L, Ledent C, Fienberg AA, Jaber M, Studler JM, Girault JA.
Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum. J
Neurosci. 2001 Jun 15;21(12):4390-9.
Corvol JC, Studler JM, Schonn JS, Girault JA, Hervé D. Galpha(olf) is necessary for coupling D1 and A2a
receptors to adenylyl cyclase in the striatum. J Neurochem. 2001 Mar;76(5):1585-8.
Valjent E, Corvol JC, Pages C, Besson MJ, Maldonado R, Caboche J. Involvement of the extracellular signalregulated kinase cascade for cocaine-rewarding properties. J Neurosci. 2000 Dec 1;20(23):8701-9.
Corvol JC, Oppenheim C, Manaï R, Logak M, Dormont D, Samson Y, Marsault C, Rancurel G. Diffusionweighted magnetic resonance imaging in a case of cerebral venous thrombosis. Stroke. 1998 Dec;29(12):264952.
Blanche P, Beuzeboc P, Vincens AL, Corvol JC, al Kaied F, Nguyen B, Galezowski N, Sicard D. Systemic lupus
erythematosus paraneoplastic syndrome. Clin Exp Rheumatol. 1997 Sep-Oct;15(5):581-2.
Beldjord C, Desclaux-Arramond F, Raffin-Sanson M, Corvol JC, De Keyzer Y, Luton JP, Plouin PF, Bertagna X.
The RET protooncogene in sporadic pheochromocytomas: frequent MEN 2-like mutations and new molecular
defects. J Clin Endocrinol Metab. 1995 Jul;80(7):2063-8.
Page 5 sur 5