Electronic Supplementary Material 1 Genetics and brain morphology

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Electronic Supplementary Material 1
Genetics and brain morphology
Lachlan T. Strike1*, Baptiste Couvy-Duchesne1, Narelle K. Hansell1, Gabriel Cuellar-Partida, Sarah E. Medland, Margaret J.
Wright
Lachlan T. Strike, Baptiste Couvy-Duchesne
Neuroimaging Genetics, QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia
School of Psychology, University of Queensland, Brisbane QLD 4072, Australia
Centre for Advanced Imaging, University of Queensland, Brisbane QLD 4072, Australia
Narelle K. Hansell
Neuroimaging Genetics, QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia
Gabriel Cuellar-Partida
Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia
Sarah E. Medland
Quantitative Genetics, QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia
Margaret J. Wright
Neuroimaging Genetics, QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia
School of Psychology, University of Queensland, Brisbane QLD 4072, Australia
1
*
LS, BCD and NH contributed equally to this work.
Corresponding author
Lachlan T. Strike
Lachlan.Strike@qimrberghofer.edu.au
Online Resource 1. Meta-analytic estimates of additive genetic (A), common or shared environmental (C) and unique or nonshared environmental (E) variance. Estimates from Blokland et al. (2012) and 3 additional studies, some of which include new
imaging phenotypes not included in Blokland et al. 2012; * denotes revised heritability estimate, and ^ denotes new phenotype.
The meta-analyses including the additional studies (Batouli et al. 2014; den Braber et al. 2013; Rentería et al. 2014) used the
same methodology as Blokland et al. (2012).
3rd third ventricle; AMYG amygdala; bilat bilateral; CB cerebellum; CAUD caudate; cGM cerebral gray matter; CT cortical
thickness; cWM cerebral white matter; FR frontal; GM gray matter; GP globus pallidus; HIP hippocampus; ICV intracranial
volume; L left; LH left hemisphere; LV lateral ventricle; NA nucleus accumbens; OCC occipital; PAR parietal; PUT putamen; R
right; RH right hemisphere; TBV total brain volume; TCV total cerebral volume; TEMP temporal; THAL thalamus; WM white
matter.
References
Batouli, S. A., Sachdev, P. S., Wen, W., Wright, M. J., Ames, D., & Trollor, J. N. (2014).
Heritability of brain volumes in older adults: the Older Australian Twins Study.
Neurobiol Aging, 35(4), 937.e935-918, doi:10.1016/j.neurobiolaging.2013.10.079.
Blokland, G. A., de Zubicaray, G. I., McMahon, K. L., & Wright, M. J. (2012). Genetic and
environmental influences on neuroimaging phenotypes: a meta-analytical perspective
on twin imaging studies. Twin Res Hum Genet, 15(3), 351-371,
doi:10.1017/thg.2012.11.
den Braber, A., Bohlken, M. M., Brouwer, R. M., van 't Ent, D., Kanai, R., Kahn, R. S., et al.
(2013). Heritability of subcortical brain measures: a perspective for future genomewide association studies. Neuroimage, 83, 98-102,
doi:10.1016/j.neuroimage.2013.06.027.
Rentería, M. E., Hansell, N. K., Strike, L. T., McMahon, K. L., de Zubicaray, G. I., Hickie, I.
B., et al. (2014). Genetic Architecture of Subcortical Brain Regions: Common and
Region-Specific Genetic Contributions. Genes, Brain and Behavior, n/a-n/a,
doi:10.1111/gbb.12177.
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