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1. Review
Mathematical models of cancer metabolism
Elke Katrin Markert and Alexei Vazquez
Published on: 22 December 2015
2. Research
Evidence that 2-hydroxyglutarate is not readily metabolized in colorectal
carcinoma cells
Susan J. Gelman, Nathaniel G. Mahieu, Kevin Cho, Elizabeth M. Llufrio, Timothy A.
Wencewicz and Gary J. Patti
Published on: 1 December 2015
3. Research
Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma
tumor growth
Laura Schöckel, Andrea Glasauer, Farhan Basit, Katharina Bitschar, Hoa Truong, Gerrit
Erdmann, Carolyn Algire, Andrea Hägebarth, Peter HGM Willems, Charlotte Kopitz,
Werner JH Koopman and Mélanie Héroult
Published on: 20 October 2015
4. Research
Targeting glutamine metabolism sensitizes pancreatic cancer to PARPdriven metabolic catastrophe induced by ß-lapachone
Gaurab Chakrabarti, Zachary R. Moore, Xiuquan Luo, Mariya Ilcheva, Aktar Ali,
Mahesh Padanad, Yunyun Zhou, Yang Xie, Sandeep Burma, Pier P. Scaglioni, Lewis C.
Cantley, Ralph J. DeBerardinis, Alec C. Kimmelman, Costas A. Lyssiotis and David A.
Published on: 12 October 2015
5. Research
The rate of glycolysis quantitatively mediates specific histone acetylation
Ahmad A. Cluntun, He Huang, Lunzhi Dai, Xiaojing Liu, Yingming Zhao and Jason W.
Published on: 23 September 2015
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Most accessed articles
Most accessed articles RSS
1. Review
Calorie restriction and cancer prevention: a mechanistic perspective
Stephen D Hursting, Sarah M Dunlap, Nikki A Ford, Marcie J Hursting and Laura M
Published on: 7 March 2013
2. Review
Linking vitamin B1 with cancer cell metabolism
Jason A Zastre, Rebecca L Sweet, Bradley S Hanberry and Star Ye
Published on: 24 July 2013
3. Research
Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse
aerobic glycolysis in cancer cells
Julia Billiard, Jennifer B Dennison, Jacques Briand, Roland S Annan, Deping Chai,
Mariela Colón, Christopher S Dodson, Seth A Gilbert, Joel Greshock, Junping Jing,
Hong Lu, Jeanelle E McSurdy-Freed, Lisa A Orband-Miller, Gordon B Mills, Chad J
Quinn, Jessica L Schneck…
Published on: 6 September 2013
4. Review
Hypoxia signaling pathways in cancer metabolism: the importance of coselecting interconnected physiological pathways
Norma Masson and Peter J Ratcliffe
Published on: 4 February 2014
5. Review
The long and winding road to the mitochondrial pyruvate carrier
John C Schell and Jared Rutter
Published on: 23 January 2013
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Editors' profiles
hi Van Dang, Editor-in- Chief
Chi Dang is a professor, physician-researcher, renowned cancer biologist and hematologistoncologist, who serves as director of the Abramson Cancer Center at the University of
"After several decades of profound advances in our understanding of the genetics and molecular
biology of cancer, it has become self-evident that metabolism and bioenergetics are regulated by
cancer genes and are intimately linked to the growth and survival of cancer cells. The obesity
pandemic connected to increased cancer risk further underscore the importance of a richer
understanding of cancer and organismal metabolism. In this regard, Cancer & Metabolism is
launched uniquely to fulfill the needs of a burgeoning field which is at the crossroads of many
scientific disciplines."
Michael Pollak, Editor-in-Chief
Michael Pollak is an internationally recognized expert in cancer endocrinology at the Lady Davis
Institute for Medical Research of McGill University and a clinical oncologist at the Jewish
General Hospital, Quebec, Canada.
"Cancer & Metabolism will provide a forum for rapid dissemination of research findings
concerning metabolic factors that influence cancer risk and cancer pathophysiology, and cancer
treatment. The scope of the Journal will allow for an interdisciplinary readership including
cancer biologists, endocrinologists, oncologists, clinical trialists and population scientists."
Cancer & Metabolism publishes selected collections of research articles, conference
proceedings, reviews and reports as supplements. While we build our new sites all supplements
will be available here.
Chi Van Dang, University of Pennsylvania, USA
Michael Pollak, McGill University, Canada
Senior Editors
Kevin Brindle, University of Cambridge, UK
Navdeep Chandel, Northwestern University, USA
Ralph DeBerardinis, University of Texas Southwestern Medical Center, USA
Eyal Gottlieb, Beatson Institute for Cancer Research, UK
Matthew Vander Heiden, Massachusetts Institute of Technology, USA
Aims and scope
Cancer & Metabolism welcomes studies on all aspects of the relationship between cancer
including Molecular biology and genetics of cancer.
Read more
Article collections
Cross journal article collection
Edited by Navdeep Chandel (on behalf of Cancer & Metabolism), Martin Brand, Andrew
Murray , Jodi Nunnari and Peter Walter
Nutrition and metabolism in health and disease
Metabolism diet and disease
Featured article: Mathematical models of cancer metabolism
Elke Katrin Markert and Alexei Vazquez review the literature on mathematical models of
metabolism and discuss the following
Identification of the selective advantage of metabolic phenotypes
How the molecular hallmarks of cancer can be related to cell proliferation and tissue remodeling
Review genome-wide gene expression analysis, flux balance models, kinetic models, reaction
diffusion models and models of the tumor micro- environment.
Read More
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Griffiths et al - Cancer & Metabolism