BASIC SCIENCE DEPARTMENT
Biochemistry & Microbiology
Principal Investigator
Title
Michael Moore, PhD
moorem@marshall.edu
304-696-7324
-Progestin stimulation of breast cancer
a) Regulation and role of manganese superoxide
dismutase
b) Regulation and role of the putative tumor
suppressor AP-2γ
c) Regulation and role of Akt
Susan Jackman, PhD
jackman@marshall.edu
304-696-7342
-The interaction of group B streptococcus with
human interleukin-6
W. Elaine Hardman, PhD
hardmanw@marshall.edu
304-696-7339
-Post-doctoral fellowship for Gabriela Ion
Attenuation of preadipocytes/breast cancer cells
communication with role in cancer prevention
-Walnut consumption for benefit against prostate
and breast cancer
-Omega-3 fat to reduce risk for breast cancer
1R01CA114018-01A2
-Inhibition of nuclear factor kappa B in indolent B
cell malignancies
Don Primerano, PhD
primeran@marshall.edu
304-696-7338
-West Virginia IdeA Networks of Biomedical
Research Excellence
-Genetic Basis of Methadone Overdose
Susceptibility
Pier Paolo Claudio, MD, PhD
claudiop@marshall.edu
304-696-3516
-Ultrasound guided gene delivery in pancreatic
cancer
-Ultrasound guided site-specific gene delivery in
prostate cancer
Richard Niles, PhD
niles@marshall.edu
304-696-7323
-Transcription factors in cancer
-Expansion of stem doctoral education at Marshall
University – RCG
Hongwei Yu, PhD
yuh@marshall.edu
304-696-7356
-Effect on DNA repair mechanisms in P.
Aeruginosa
-Developing a genetic system to evaluate the
radiation effect on DNA damage and repair water
pollutants
-Genetic analysis of radiation effect on DNA repair
mechanisms in P. Aeruginosa
-Apoptosis & disease progression in a mouse model
for polycystic kidney disease
Pharmacology, Physiology & Toxicology
Jung Kim, PhD
kimj@marshall.edu
304-696-2682
-Genetics of diet-induce obesity in a new mouse
model
-Diet-Wnt signaling interactions in a novel congenic
mouse model of obesity
Richard Egleton, PhD
egleton@marshall.edu
304-696-3523
-Diabetes and the blood brain barrier
-EGCG regulation of drug efflux transporters
-Ecstasy metabolite transport into the brain
-peptide based drug delivery
Nalini Santanam, MPH
santanam@marshall.edu
304-696-7321
-Oxidized lipids in cardiovascular disease
-Obesity related biomarkers in patients with
coronary artery disease in the appalachian region
-Pain, oxidation and endometriosis
-Again, epicardial fat and cardio-metabolic risk
-Nicotine, microRNAs and atherosclerosis
-Obesity associated hypertension: Role of 12lipoxygenase and perivascular fat
Monica Valentovic, PhD
valentov@marshall.edu
304-696-7332
-S-adenosylmethionine modification of
acetaminophen toxicity
-Effects of resveratrol on cisplatin nephrotoxicity
-Mechanism of radiocontrast media renal toxicity
Piyali Dasgupta, PhD
dasgupta@marshall.edu
304-696-3612
-Nicotine/Acetylcholine signaling in lunch cancer
-Nicotine receptor signaling in non-small cell lung
cancer
-Nicotine receptor antagonists in therapy of lung
cancers
-Nicotine receptor signaling in atherogenesis
-Nicotine receptor signaling in retinal angiogenesis
-Anti-neoplastic activity of capsaicin in human
small cell lung cancer
Lawrence M. Grover, PhD
grover@marshall.edu
304-696-7328
-Models of signaling mechanisms in LTP
-Growth hormone mechanisms in the regulation of
hippocampal synaptic function
-Mechanisms underlying effects of SNRI’s on
synaptic plasticity and plasticity related molecules
CLINICAL DEPARTMENTS
Department of Cardiovascular Services
Paulette Wehner, MD
wehner@marshall.edu
304-697-1166
-Randomized evaluation of long term anticoagulant
therapy comparing the efficacy and safety of two
blinded doses of dabigatran etexilate with open
label warfarin for the prevention of stroke and
systemic embolism in patients with non-valvular
atrial fibrillation: prospective, multi-centre, parallelgroup, non-inferiority trial
-RELY-ABLE: long term multi-center extension of
dabigatran treatment in patients with atrial
fibrillation who completed the RE-LY trial and a
cluster randomized trail to assess the effect of a
knowledge translation intervention on patient
outcomes
Silvertre Cansino, MD
cansino@marshall.edu
304-697-1166
-Treatment of preserved cardiac function heart
failure with an aldosterone antagonist
Mark Studeny, MD
studeny@marshall.edu
304-697-1166
- A randomized, double blind, parallel-group study
of cardiovascular safety in osteoarthritis or
rheumatoid arthritis patients with or at high risk for
cardiovascular disease comparing celecoxib with
naproxen and ibuprofen
-A prospective evaluation in a randomized trial of
the safety and efficacy of the use of the TAXUS
element paclitaxel-eluting coronary stent system for
the treatment of De Novo Coronary Artery Lesions
-A prospective evaluation in a non-randomized trial
of the safety and efficacy of the use of the TAXUS
element paclitaxel-eluting coronary stent system for
the treatment of De Novo Coronary Artery Lestions
in small vessels
-A comparison of prasurgrel and clopidogrel in
acute coronary syndrome (ACS)subjects with
unstable angina/non-st-elevation myocardial
infarction (UA/NSTEMI) who are medically
managed
-XIENCE V Everolimus eluting coronary stent
system (EECSS) USA post-approval study
Department of Family Medicine
Dilip Nair, MD
nair@marshall.edu
304-691-1162
-Perspectives of family medicine residents on
residency curriculum regarding worldview thinking
in patient care
Department of Internal Medicine
Maurice Mufson, MD
mufson@marshall.edu
304-691-1050
-An open, randomized, multicenter study of the
safety, tolerability, and immunogenicity of
VAQTATM given concomitantly with PedvaxHIBTM
and InfanrixTM in Healthy Children 15 months of
age
-An expanded phase 1/2A randomized, doubleblind, placebo-controlled study to evaluate the
safety, tolerability, immunogenicity, and viral
shedding of MEDI-560, a live, attenuated
recombinant parainfluenza virus type 3 (PIV#)
vaccine, administered intranasally to healthy infants
1 to <12 months of age
-A phase II randomized, observer blind, multicenter
study of GlaxoSmithKline Biologicals’ combined
measles-mumps-rubella-varicella vaccine (MMRV)
versus Proquad®, according to a one does schedule,
both administered sub-cutaneously at 12-14 months
of age, concomitantly with Hepatitis A vaccine
(HAV) and Pneumococcal Conjugate Vaccine
(PCV) but at separate sites.
-A phase 1/2A randomized, double-blind, placebocontrolled, dose-escalation study to evaluate the
safety, tolerability, immunogenicity and vaccinelike viral shedding of MEDI-534, a live, attenuated
intranasal vaccine against respiratory syncytial virus
(RSV) and parainfluenza virus type 3 (PIV3), in
healthy infants 6 to <24 month old children and in 2
month old infants
-A phase II, randomized, observer blind, controlled,
multicenter study to assess immunogenicity and
antibody persistence following vaccination with
GlaxoSmithKline’s Candidate combined measles,
mumps, and rubella vaccine (MMR) versus M-MR®II as a first-dose, both administered subcutaneously at 12-15 months of age, concomitantly
with Hepatitis A vaccine (HAV), Varicella Vaccine
(VV) and pneumococcal conjugate vaccine (PCV)
but at separate sites
-Efficacy Evaluation of Pneumococcal Vaccine
-Data mining of the IDX database in Medicine for
studies on vaccines mainly influenza vaccine and
pneumococcus vaccine
Lynne Patterson, MD
patter10@marshall.edu
304-691-1000
-Sulfapyridine supplies for clinic patient
Thomas Rushton, MD
rushton@marshall.edu
304-691-1062
-Analysis and molecular epidemiology of common
and resistant human pathogens in a micropolis
population
-Who is colonized with MRSA in relation to a
source patient
-Who is colonized with MRSA in an incarcerated
population
-The effect of energy exercise on CD4 lymphocyte
counts, HIV viral loads and perception of well
being in an HIV/AIDS population
-Prospective observational study on predictors of
early on treatment response and sustained
virological response in a cohort of treatment naïve
HCV-infected patients treated with pegylated
interferons
-An international, multicenter, prospective,
observational study of the safety of maraviroc used
with optimized background therapy in treatment
experienced HIV-1 infected patients
Department of Neuroscience
Mark Stecker, MD, PhD
stecker@marshall.edu
304-526-6387
-Ischemia in peripheral nerve
-Effects of various types of trauma on peripheral
nerve
-Properties of clinical electrodes with continuous
and intermittent stimulation
-Information content in constrained signals
Toussaint Leclercq, MD
leclercq@marshall.edu
304-691-1812
-Ultrasonic removal of intervertebral disc
-Safety of ultrasonic surgery in relation to proximity
work for peripheral nerves
-Mechanisms of pain relief in the treatment of lower
limb chronic pain in patients with PVD
-Anatomy of the lumbar intervertebral disc in
relation to surgical insertion of prosthetic devices
Department of Obstetrics & Gynecology
David Chaffin, MD
chaffind@marshall.edu
304-691-1455
-Outcomes of fetuses with absent or reversed end
diastolic velocity in the umbilical artery using
Doppler volocimetry
-The effect on neonatal outcomes of managing
maternal hypertension using maternal cardiac
dynamics to guide antihypertensive therapy
-Prevalence of drug use in pregnant West Virginia
patients
Shailini Singh, MD
ssingh@marshall.edu
304-691-1459
-Routine follow up of ultrasound performed at
Cabell Huntington Hospital Perinatal Center
Brenda Dawley, MD
dawleyb@marshall.edu
304-691-1423
-Review of stillbirths (>20 wks gestation) to
determine cause and if evaluation complies with
ACOG recommendations
-Prospective study to determine degree of urethral
impringment that occurs with uteral sacral rixation
by MRI measurement pre and post operatively
-A retrospective review of term labor patients to
determine the compliance with CDC guidelines for
intrapartum group B streptococci prophylaxsis
-A retrospective review of group B streptococci
prophylaxsis in preterm pregnancy
Department of Orthopedics
Felix Cheung, MD
cheungf@marshall.edu
304-691-1259
-Study the use of computer modules to teach
medical students orthopedic topics
Ali Oliashirazi, MD
oliashirazi@marshall.edu
304-691-1274
-Randomized clinical trial to investigate the efficacy
of mannitol in improving leg perfusion pressure in
closed tibia fractures
Department of Pediatrics
Yoram Elitsur, MD
elitsur@marshall.edu
304-691-1381
-Acanthosis nigricans as a clinical marker for
insulin resistant diabetes mellitus in obese children
-Season distribution of eosinophilic esophagitis
(EoE) in children from West Virginia
-Familial clustering of habitual constipation: A
prospective study in children from West Virginia
-Helicobacter pylori diagnostic tests in children: a
review of the literature from 1999 to 2009
-Fluticasone reversed sub-epithelial fibrosis in
children with eosinophilic esophagitis
-A randomized, double-blind, parallel-group study
to assess the safety and efficacy of Asacol® (1.2 to
4.8 g/day) administered as 400 mg delayed-release
tablets given every 12 hours for 6 weeks to children
and adolescents with mildly to moderately active
ulcerative colitis
-A randomized, double-blind, parallel-group study
to assess the safety and efficacy of Asacol® (1.2 to
4.8 g/day) 400 mg delayed-release tablets given
twice daily for 26 weeks to children and adolescents
for the maintenance of remission of ulcerative
colitis
James Lewis, MD
lewisj@marshall.edu
304-691-1300
-Constipation – ADHD – and tic study (CATS)
association of constipation, ADHD and tics (CATS)
and the therapeutic effectiveness of stimulants on
improving encopresis
Bob Miller, MD
miller12@marshall.edu
304-691-1372
-The use of CBC and CRP for evaluating sepsis in
the neonate
-Respiratory outcomes using NCPAP vs. CPAP in
premature infants >1500 g
Edward Pino, MD
pinoe@marshall.edu
304-691-1380
-Catheter associated bloodstream infections in the
PICU
-Shaken baby syndrome in WV-Occurrence,
morbidity, mortality and cost
Amy Lochow, MD
alochow@marshall.edu
304-691-1300
-Kidnitiative West Virginia and Healthykids
Pediatric obesity prevention pilot
Jessie Shields, MD
antosze1@marshall.edu
304-691-1300
-The rates of MRSA colonization among members
of the medical staff at CHH
-Babies offered only Breast - ????
Joseph Werthammer, MD
werthammer@marshall.edu
304-691-1360
-Pulmonary embolism presenting with sudden
respiratory failure in two previously stable neonates
-A decrease in retinopahy of prematurely (ROP) in
extreme preterm infants managed with continuous
positive airway pressure
-Unusual left atrial appendage thrombosis in a
neonate with poor ventricular contractibility
R. Domanico, MD
domanico@marshall.edu
304-691-1377
Documenting the NICU design dilemma: parent and
staff perceptions of open ward versus single family
room units
-Improved medical outcomes in neonatal intensive
care signle family room units compared to open
wards
Hongwei Yu, MD
yuh@marshall.edu
304-696-7356
-Genetic analysis of radiation effect on DNA repair
mechanisms in P. aeruginosa
-WV water quality: fecal source tracking and
pathogen profiling
-Novel biopolymers for space exploration
-Developing a genetic system to evaluate the
radiation effect on DNA damage & repair
University Eye Surgeons
Michael Krasnow, DO, PhD
mkrasnow@marshall.edu
304-691-8800
-Retrospective chart review: The McDowell County
digital retinal program
-Case review on the effects of using avastin in
trabeculectomy patients