Last Updated:
April 1, 2011
MOHAMMAD ATHAR, Ph.D.
Professor and Vice-Chair of Dermatology
Co-Director, Skin Disease Research Center.
University of Alabama at Birmingham
VH 509
1530 3RD AVE S
BIRMINGHAM AL 35294-0019
Office: (205)934-7554
Fax: (205)934-7500
mathar@uab.edu
Home: 205-481-8949
Cell: (917)535-8178
ma493@columbia.edu
PERSONAL INFORMATION
May 15, 1957
Lucknow, India
Indian Citizenship
Permanent Resident –USA
Home Address: 1462 Waterside Circle, Hoover, AL 35244
Marital Status: Married to Rubina Shafi, Ph.D.
Child:
Alashahmir Mohammad Athar
EDUCATION
1975
Lucknow University,
Lucknow, India
B.Sc.: Chemistry, Botany, Geology
1977
Lucknow University,
Lucknow, India
M.Sc.: Inorganic Chemistry
1978
Aligarh Muslim University,
Aligarh, India
M. Phil.: Chemistry (Coordination Chemistry)
1980
Aligarh Muslim University,
Aligarh, India
Ph.D.: Chemistry (Coordination Chemistry)
TRAINEESHIPS
1977-1981
Research Fellow, Chemistry Department, Aligarh
Muslim University. Aligarh. India.
1984
Winter School on Biological Applications of Magnetic
Resonance at the Indian Institute of Science, Bangalore,
India (September-October, 1984).
1988
Applications of Electron Spin Resonance Spectroscopy
spin-trapping techniques to detect free radicals in
biological system at the National Biomedical ESR
Center, Wisconsin Medical College, Milwaukee, WI
(July-August. 1988).
COUNTRIES VISITED
Canada, Dubai, France, Germany, Iran, K.S.A., Kuwait,
Mexico, Turkey, USA
ACADEMIC APPOINTMENTS
1981-1983
Lecturer, Post Graduate Department of Chemistry,
Shibli National College,
Azamgarh (Affiliated to
Gorakhpur University), India.
1983-1986
Scientist, Industrial
Lucknow, India.
1986-1989
Visiting Scientist, Department of Dermatology, Case
Western Reserve University, Cleveland, Ohio, OH
44106, USA.
1989-1990
Senior Scientist, Industrial
Centre, Lucknow, India.
1990-1998
Professor of Toxicology, Faculty of Science, Hamdard
University, New Delhi, 110062, India.
1990-1992
Dean, Students' Welfare, Hamdard University, New
Delhi, India.
1992-1994
Dean, Faculty of Science, Jamia Hamdard (Hamdard
University), Hamdard Nagar, New Delhi 1100 62.
1990-1998
Chair, Department of Medical Elementology and
Toxicology, Jamia Hamdard (Hamdard University),
Hamdard Nagar, New Delhi.
2
Toxicology
Research
Toxicology
Centre,
Research
1996-1998
Dean, Faculty of Science, Jamia Hamdard (Hamdard
University), Hamdard Nagar, New Delhi 1100 62.
1998-2001
Visiting Senior Research Scientist, Department of
Dermatology, Columbia University, New York 10032,
USA.
2001- 2004
Senior
Research
Scientist,
Department
of
Dermatology, Columbia University, New York 10032,
USA.
2004- 2005
Professor & Chairman of Toxicology, Faculty of
Science, Hamdard University, New Delhi, 110062, India.
2005- 2007
Senior Research Scientist, Department of
Dermatology, Columbia University, New York 10032,
USA.
2007- Present
Adjunct Senior Research Scientist, Department of
Dermatology, Columbia University, New York 10032,
USA.
2007- Present
Professor of Dermatology (with Tenure), School of
Medicine, University of Alabama at Birmingham,
Birmingham, AL, USA.
2007- Present
Co-Director,
Skin
Disease
Research
Center,
Department of Dermatology, University of Alabama at
Birmingham, Birmingham, AL, USA.
2007- Present
Senior Scientist, UAB Comprehensive Cancer Center,
University of Alabama at Birmingham, Birmingham, AL,
USA
2009- Present
Vice-Chair, Basic Science Research, Dermatology,
School of Medicine, University of Alabama at
Birmingham, Birmingham, AL, USA.
3
HONORS
Recipient of Merit Scholarships, bursary, fellowships from Class
VII to Ph.D.
1988
Hoechst-Russell Research Fellowship
Dermatology Foundation, U.S.A.
awarded
by
the
1988
NIH Training Grant awarded to spend two weeks at the National
Biomedical ESR Centre. Milwaukee, Wisconsin, U.S.A.
1989
UNESCO Young Scientist Award given for the outstanding
contribution in the field of Chemistry and Toxicology in South
Central Asia.
1994
S. Z. Qasim Gold Medal in the recognition of scientific
contribution by the Society of Biosciences, India.
1997
WEC-IIEE-IAEWP Environment Award in recognition of
outstanding contribution in the area of Toxicology and
Environmental Research by the World Environmental Congress,
India.
1994
Fellow, Society of Biosciences, India.
1996
Fellow, Society of Toxicology, India.
1997
Fellow, National Academy of Sciences, India.
FELLOWSHIP AND GRANT SUPPORT
COMPLETED
1991 - 1994
Novel Superoxide Dismutase Mimics: Approaches for
Biomedical Applications, from Council of Scientific &
Industrial Research, New Delhi
US$10,000(Indian Rupees. 400, 000)
Principal Investigator
1996 – 1998
Studies on phytochemical and pharmacological basis of
action of marine drugs used in Indian (unani) system of
medicine from the Department of Ocean Development,
Govt. of India
US$15,000(Indian Rupees.700, 000)
Principal Investigator
4
1997 - 2002
Development of pharmacopoeial standards of ISM drugs
of the Department of Indian System of Medicine, Ministry
of Health and F.W, Government of India
US$35,000 (Indian Rupees 1,450,000)
Principal Investigator
1998 - 2000
Palm oil as a potent cancer chemopreventive agent:
Studies on the inhibitory role of palm oil on foresomatch,
lung, liver and skin carcinogenesis, From Technology
Mission of Government of India awarded through the
Council of Scientific and Industrial Research
US$85,000 (Indian Rupees 3,800, 000)
Principal Investigator
9/1/98-8/31/01
NIH/NIEHS R01 ES01900
“Skin Cancer – Role of UVB Induced Cell Cycle
Alterations”
US$ 483,000 (Direct)
Co-Investigator
7/1/99 – 6/30/04
NIH/NCI U19 CA81888
“Basal Cell Carcinoma Chemoprevention in BCNS
Patients”
US$ 1,025,000 (Direct)
Co-Investigator
9/30/01 – 9/29/03
NIH/NCI N01-CN-15109
“Ptch+/- heterozygous mice over-expressing ODC: A
chemoprevention model for basal cell carcinoma”
US$ 260,061 (Direct)
Co-Investigator
11/1/01 – 10/31/03
Pfizer Pharmaceuticals
“Evaluation of MAP Kinase Activities in the murine
model of UVB-induced Cutaneous Inflammation”
US$ 418,895 (Direct)
Principal Investigator
11/1/01-10/31/03
Roche Pharmaceuticals
“Proteins Important to Isotretinoin Metabolism and
Actions in Cultured Human Skin Keratinocytes,
Fibroblasts, Sebocytes and Melanocytes”
US$ 855,391 (Direct)
Co-Principal Investigator
7/1/02-6/30/07
NIH/NIEHS R01
“Basal cell carcinoma: Molecular pathogenesis and
prevention”
US$ 1,112,500 (Direct)
Co-Investigator
5
01/01/03 – 12/31/05
NIH/NCI N01-CN-35006-72
“Effects of topically applied chemopreventive agents
and diet in SKH-1 mice: A chemopreventive model for
squamous cell carcinoma”
US$ 258,808 (Direct)
Principal Investigator
01/01/03 – 12/31/05
NIH/NCI N01-CN-15011-72
“Effects of topically applied chemopreventive agents
and diet on Ptch-/+ heterozygous mice: A
chemopreventive model for basal cell carcinoma”
US$ 268,645 (Direct)
Principal Investigator
04/1/03-03/31/06
NIH/NCI R03
“Chemoprevention of UVB-induced Basal cell
carcinomas in ptch+/- knockout mice”
US$ 100,000 (Direct)
Principal Investigator
7/1/04-6/30/07
NIH/NIEHS R01
“Role of cyclin D1 in non-melanoma skin cancer
development”
US$ 1,112,500 (Direct)
Co-Investigator
01/01/06-12/31/06
Lehman’s Brother
“Role of the TGF-β Signaling Pathway in NMSC”
US$ 25,000 (Direct)
Principal Investigator
09/01/05 – 04/30/07
NIH/NCI N01-CN-43300
“Effect of chemopreventive agents on the development
of BCCs and SCCs in the Ptch-/+ hairless mouse”
US$ 473,994
Principal Investigator
1/01/02 - 09/29/09
NIH/NCI-CN-015136
“Phase II Clinical Trial of Topical T4 Endonuclease V to
Prevent Non-melanoma Skin Cancer in Organ Allograft
Recipients”
US$ $305,541 (Direct)
Co-Investigator
12/01/07 – 11/30/10
NIH/NCI/N01-CN-43300
“Effects of chemopreventive agents on the development
of basal cell and squamous cell carcinomas in Ptc1-/+
heterozygous hairless murine model”
US$ 492, 000
Principal Investigator
6
ACTIVE GRANT SUPPORT
08/01/04 - 7/31/14
NIH/NIAMS-P30 AR050948-04
The UAB Skin Diseases Research Center
US$394,693 (Direct)
Co-Director
09/30/06 – 05/30/12
NIH/NIEHS/NCI R01-ES-015323
“Role of p53 and ptc tumor suppressive pathways in
BCCs development and prevention”
US$ 1,187,500 (Direct)
Principal Investigator
08/01/09 - 7/31/12
NIH/NIEHS/NCI R21-ES-017494
“Developing a murine model for arsenic-induced skin
neoplasm”
$275,000(Direct)
Principal Investigator
09/01/09 – 06/30/12
NIH/NCI/N01-CN-43300
“Combinatorial effects of chemopreventive agents on
the development of basal cell and squamous cell
carcinomas in Ptc1-/+ heterozygous hairless mice ”
US$ 497, 350
Principal Investigator
03/03/11 - 02/28/16
R01-CA-138998
“Inhibiting multiple molecular targets for preventing
non-melanoma skin cancer”
NIH/NIEHS/NCI
$1030,000 (Direct)
Principal Investigator
7
DEPARTMENTAL AND UNIVERSITY COMMITTEES:
Dec., 1990
Served as an Expert for developing an audiovisual
teaching support (movie) for undergraduate students
sponsored by Indira Gandhi National Open University,
New Delhi.
1990-1998
Chairman, Board of Studies, Department of Medical
Elementology & Toxicology, Hamdard University, New
Delhi.
1992-1994
Chairman, Board of Research Studies.
1993-1998
Consultant for Toxicity Evaluation of various products of
Government and Non-Government Organizations.
1996-1998
Chairman, Board of Research Studies.
1996 -1998
Member,
Committee
for
the
selection
of
Lecturers/Readers/Professors of a number of Indian
universities.
1996 - 1997
Member, Committee for the promotion of Scientists to
various senior grades for the Ministry of Defence,
Government of India.
1996 - 1997
Member, Selection Committees of
Sciences of Bose Institute, Calcutta.
1997-1998
General Secretary, Society of Toxicology, India
1997
Member, Advisory Committee meant for establishing
Biotechnology and Molecular Biology in the School of
Basic Sciences, Ambedkar University, Agra.
1990-1998
Served as a member of various committees constituted
time to time for purchases, organizing seminars,
symposia, conferences, board of research studies, etc.
1990-1998
Chaired/acted as convenor of various committees.
These include committees for formulation of courses,
instrumentation, animal house, board of studies etc.
1990-1998
Member-in-Charge,
Hamdard.
1990-1998
Member, Academic Council, Jamia Hamdard.
1990-1998
Member, Planning
Hamdard.
8
University
and
Environmental
Development,
Monitoring
Board,
Jamia
Jamia
1992-1998
Member, Executive Council, Jamia Hamdard.
1992-1998
Member, Society, Jamia Hamdard.
2001-2004
Member, Columbia University Health Sciences
Institutional Animal Care and Use Committee (IACUC).
2005
Member, Selection Committees of the Central Drug
Research Institute, Lucknow
2005
Member on the Selection Committees of Public Service
Commission, J & K.
2007-present
Member, Promotion and Tenure Committee, Department
of Dermatology, University of Alabama at Birmingham
TEACHING and RESEARCH EXPERIENCE
1978 – 1983
Teaching theory and Laboratory classes of analytical
inorganic
chemistry,
coordination
chemistry,
spectroscopy and bio-inorganic chemistry to B.S. and
M.S. students. Syntheses of coordination compounds of
transition metals; applications of spectroscopic
techniques (Viz. I.R., N.M.R., E.S.R., Mossbauer and
electronic spectroscopy) to elucidate the structure and
stereochemistry of synthesized compounds. Bio-mimetic
chemistry.
1990 – 2005
Teaching of principles and mechanisms of occupational,
metal and environmental toxicology and carcinogenesis
to M.S. residents and Ph.D. students. Murine models for
investigating molecular pathogenesis of human cancers;
Apoptosis and Cell cycle regulation; Molecular basis for
developing approaches for chemoprevention of cancer;
Oxidative mechanisms of chemical toxicity; Role of
oxygen radicals in tumor promotion and progression;
Metabolic basis of chemical carcinogenesis and cancer
chemoprevention, correlation of DNA damage with
cancer induction; Photodynamic therapy of cancer with
reference to the role of reactive oxygen species; Heavy
metal toxicology; study of biochemical alterations in liver
and kidney following exposure to heavy metals; Study of
interaction of toxic metals with essential trace metals;
and therapeutic agent as antidotes for toxic metals and
Role of oxidative stress in the manifestation of metal
toxicity.
9
1989-Present
On the Panel of Examiners for M.Sc./Ph.D. Students of
Lucknow University, Lucknow; Delhi University, Delhi;
Jawahar Lal Nehru University, New Delhi; Jamia Millia
Islamia, New Delhi; IIT, Delhi; A.P.S. University, Rewa;
Aligarh Muslim University, Aligarh; Kashmir University,
Srinagar; Bhopal University, Bhopal; Kanpur University,
Kanpur; Agra University, Agra; Punjab University,
Chandigarh; Meerut University, Meerut; Gaya University,
Bodh Gaya; Bombay University, Mumbai; North Eastern
Hill University, Shillong; Manipal University, Mangalore;
UP Technical University, Lucknow, India; Eastern
American University, Albuquerque, New Mexico, USA.,
MENTORED SCHOLARS
I.
Ph.D. Scholars
Year
1983-1986
1983-1986
1990-1994
1992-1996
1992-1996
1992-1996
1992-1996
1994-1998
1994-1998
1994-1998
1994-1998
1994-1998
1996-2000
1996-2000
1997-2002
1997-2003
1997-2003
1997-2003
2000-2004
Names
Manoj Misra
S. K. Srivastava
Shakir Ali
Mohammad Iqbal
Uma Giri
Hasan Razazadeh
Haider Ali Khan
Sabah Ansar
Gayetri Bhasin
Hina A. Kausar
Prashant Trikha
Ayesha Rahman
M.Afzal Zargar
Tarvinder Taneja
Mukesh K. Agarwal
Manjari Mohan
Gurpreet Kaur
Nupur Malhotra
Saba Khan
Present Position
Sr.Scientist (USA)
Scientific Officer (India)
Professor (India)
Scientist (Japan)
Scientist (USA)
Assoc.Professor (Iran)
Assist.Professor (India)
Post Doctoral Scientist (USA)
Patent Scientist (India)
Post Doctoral Scientist (India)
Post Doctoral Scientist (India)
Post Doctoral Scientist (USA)
Professor (India)
Post Doctoral Scientist (UK)
Post Doctoral Scientist (USA)
Editor/Scientist
Post Doctoral Scientist
Post Doctoral Scientist
Post Doctoral Scientist
II. Post-doctoral Fellows
1990-1991
1990-1992
1992-1994
1994-1996
1996-1998
1996-1998
2000
2000-2001
Dr. Sarwat Sultana
Dr. M. Y. Siddiqui
Dr. S.D. Sharma
Dr. N. Hasan
Dr. S. Sahdev
Dr. M. Iqbal
Dr. K. Morel
Dr. Kathy An
10
Associate Professor (India)
Scientific Officer(Saudi Arabia)
Scientific Officer (India)
Consultant (Saudi Arabia)
Associate Professor (India)
Asst. Professor (Malaysia)
Assistant Professor (USA)
Resident (USA)
2001-Present
2002-2003
1999-2005
2005-2006
2006-2007
2007-2008
2008-2009
2008-present
2009-present
2009-present
Dr. Xiuwei Tang
Assoc. Scientist (USA)
Dr. Juliette Lee
Resident (USA)
Dr. Gayetri Bhasin
Documentation Scientist (India)
Dr. Sara Herman
Resident (USA)
Dr. Liguang Zhang
Post-doctoral Scientist (USA)
Dr. Jian-He Wu
Post-doctoral Scientist (USA)
Dr. Stephnie E Beatrous Resident (USA)
Dr. Jiamin Xu
Res. Assoc. Scientist (USA)
Dr. Zoe Verney
Post Doctoral Scientist (USA)
Dr. Sandeep Chaudhary Post Doctoral Scientist (USA)
NATIONAL AND INTERNATIONAL EDITORIAL BOARDS
Reviewer for the Journals
1988
Fundamental and Applied Toxicology, an official journal of
Society of Toxicology, U.S.A., Published by the Academic
Press, U.S.A.
1987 – 1989
Synthesis and Reactivity in Inorganic and Metal-organic
Chemistry published by the Marcel Dekker Press, New York,
U.S.A.
1995 -1998
Indian J. Exp. Biol., Published by CSIR, New Delhi, India.
1999 –present
Experimental Dermatology, Munksgaard Publishers,
Copenhagen.
2000-present
Bulletin of Environmental Contamination & Toxicology,
Springer-Verlag, New York.
2000
Environmental Geochemistry & Health, Kluwer Academic
Publishers, The Netherlands
2000-present
Life Sciences, Elsevier Science Publishers, USA.
2000-present
Photochemistry & Photobiology, Published by the American
Society for Photobiology, USA.
2000 –present
Cancer Research, Published by the American Association for
Cancer Research.
2001-present
Biochem. Biophys. Acta, Elsevier Science Publishers, USA.
2002 –present
Arch. Biochem. Biophys., Academic Press, USA.
2002-present
J. Clin. Invest., Rockefeller Press, USA.
11
2002-present
Neoplasia, Nature Press, USA.
2002
J. Cellular Physiol., Wiley-Liss Press, USA. (2002);
2002-present
Toxicol. Appl. Pharmacol., Academic Press, USA
2002
Intl. J. Radiation Oncol.
2002
Histology & Histopathology
2002
Clin. Cancer Research, Published
Association for Cancer Research.
2003-present
J. Pharmacy Pharmacol., Pharmaceutical Press, UK
2003-present
Cancer Letters, Elsevier Science Publishers, USA
by
the
American
2003
J. Cellular Biochem., USA
2003
Nutrition and Cancer, USA
2003
Breast Cancer Research and Treatment, Kluwer Academic
Publishers
2005
Free Radical Biology and Medicine
2005
Biochemical Pharmacology
2005
Indian Journal of Cancer
2006
Journal of Applied Toxicology
2006
Journal of Nutritional Biochemistry
2006-present
Journal of Pharmacology and Experimental Therapeutics
2006-present
Mol. Cancer Therap., Published by the American Association
for Cancer Research
2006-present
Biochemistry, American Chemical Society, USA
2007
Gene
2008-present
Chemical Research in Toxicology, American Chemical
Society, USA
2008-present
Molecular Carcinogenesis, Elsevier Science Publishers, USA
2008-present
Biochem. Biophys. Acta Sinica, China.
12
2008-present
Journal of Cellular and Molecular Medicine, USA
2010-present
International Journal of Biological Macromolecules, Elsevier
Science Publishers, USA
2010-present
Shock, Shock Society, USA
2010-present
Journal of Comparative Physiology B
Editorial Boards
1992 - 1995
Member, Editorial Board, International Journal of Toxicology,
Occupational and Environmental Health, Wiley Eastern
Limited, New Delhi, INDIA
1994 – 1997
Member, Editorial Board, Indian J. Toxicol., an official
publication of the Society of Toxicology, India.
1997 - present
Member, Editorial Board,
Research, Aligarh, India.
2003 - 2008
Member, Editorial Board, Toxicology
Pharmacology, Academic Press, USA.
2008 - present
Member, Editorial Board, Clinical, Cosmetic and
Investigational Dermatology, Dove Medical Press, USA.
Chemical
&
Environmental
and
Applied
Editorships
1989-1996
Associate Editor, Synthesis and Reactivity in Inorganic and
Metal-organic Chemistry published by the Marcel Dekker
Press, New York. U.S.A.
1997 -1999
Editor, Indian J. Toxicol., an official publication of the Society
of Toxicology, India.
2003 - 2007
Consulting Editor, Journal
Rockefeller Press, USA.
2006 - 2007
Guest Editor, Special Issue, Toxicology and Applied
Pharmacology, Academic Press, USA.
13
of
Clinical
Investigation,
Consultative
1992 - 2001
Member, panel of reviewers of grant applications for research
projects, Department of Science and Technology,
Government of India, New Delhi.
1994
Expert
Member
for
the
evaluation
&
funding
recommendations of research projects of All India Council for
Technical Education, Ministry of Human Resources
Development, New Delhi.
1994 - 1995
On the Panel of Experts for the evaluation & funding
recommendations of research projects, Indian Council of
Medical Research, New Delhi.
1995 - 1996
On the Panel of reviewers for the evaluation & funding
recommendations of research projects, Bhabha Atomic
Research Centre, Bombay.
1996 - 1999
Member, Expert Committee to award Research Projects and
to approve thrust area guidelines for the Indian Council of
Agriculture Research, Government of India, New Delhi.
1997
Member, Expert Committee of University Grants Commission
to monitor the utilization of funds provided to universities in
VIII five year plan and to make recommendations for IX five
year plan.
1998 - 2002
On the panel of reviewers for the evaluation & funding
recommendations of research projects, Department of
Environment and Forest, Government of India, New Delhi.
1999 - Present
Adhoc Member, Expert Committee to award research
projects, Ohio Cancer Research Associates, Columbus, OH,
USA.
1999 - 2007
Expert Reviewer, Alexander
Fellowship, Bonn, Germany.
2002 -present
Adhoc Member for Grant Review of National Institutes of
Health (NIH), Bethesda, MD, USA: Center for Scientific
Review Special Emphasis Panels:
NCCAM Study Section ZAT1 CP(05), March 10-11, 2003
NCCAM Study Section ZAT1 CP(07), June 9-10, 2003
NCCAM Study Section ZAT1 CP(11), November 24-25,
2003
Challenge Grant Panel ZRG1 MOSS-C(58)R, July 2021,2009
NCI-SPORE Review ZCA1 RPRB-M(O1) June 15-16, 2010;
Pathology B Study Section July 16, 2002
14
Von
Humboldt-Stiftung
Chemical Pathology A Study Section June 17-18, 2003
Cancer Etiology Study Section October. 16-17, 2006
Arthritis, Connective Tissue and Skin Study Section January
17-18, 2008,
2006 -2007
Adhoc Member, University of Connecticut Center for Health,
Intervention and Prevention, Farmington, CT, USA.
2006 -present
Adhoc Member, National Medical Research Council,
Singapore
.
2006 -present
Adhoc Member, Associazione Italiana per la Ricerca sul
Cancro, Italy
2008 -
Adhoc Member, Bart and the London Charity, UK.
2010-present
Adhoc Member, Ministry of Health, Republic of Italy
2010-present
Member external advisory committee of NIH U54
(Countermeasures against chemical threats) Program
entitled “Novel antioxidant therapeutics for sulfur mustard
toxicity”, Department of Pediatrics, National Jewish Health
and University of Colorado, Denver.
15
PUBLICATIONS:
Original, Peer Reviewed Articles
1. Siddiqui AR, Nabi A, Athar M, Ahmad N. Selective spectrophotometric
determination of U(VI) using salicyldiimine antipyrine. Z. Anal. Chem. S305:
410, 1981.
2. Shahma, Athar M, Ahmad N. Complexes of trivalent lanthanide ions with schiff
bases derived from Vanillin and triethylenetetraamine. Indian J. Chem.
21A:85-187, 1982.
3. Siddiqui AR, Nabi A, Athar M, Ahmad N. Selective microgram detection of Fe
(III) on ion exchange resin beads. J. Indian Chem. Soc. LIX:1200, 1982.
4. Gupta AA, Sen Gupta AK, Athar M, Ahmad N. Antibacterial properties of some
metal complexes derived from N,N'-p-dimethylaminobenzaldazine and
furfuraldazine. J. Antibact. Antifung. Agants (Jpn.). 10:298-301, 1982.
5. Athar M, Ahmad N, Gupta AA, Sen Gupta AK. Synthesis and antibacterial
activity of the complexes of bis(furaldehyde)benzidine. Indian Drugs. 20:225228, 1983.
6. Athar M, Ahmad N. Studies on the complexes of bis(thiophene 2-carboxaldehyde)O-tolidin with transition metal ions. Indian J. Chem. 22A:10551057, 1983.
7. Gupta AA, Srivastava N, Sengupta AK, Athar M. Studies on potential juvenile
hormone analogs. Indian J. Chem. 22B:948-955, 1983.
8. Kulkarni YD, Srivastava S, Abidi SHR, Athar M. Synthesis and reactivity of
some (2- and 4-substituted) benzoyl tellurium dichlorides. Synth. React. Inorg.
Met.-org. Chem. (USA). 15:1043-1060, 1985.
9. Kulkarni YD, Srivastava S, Athar M. Characterization of keto-enol forms of some
organotellurium compounds derived from bromopropiophenone. Indian J.
Chem. 24A:1067-1071, 1985.
10. Athar M. Shahma A, Ahmad N. Synthesis, structure and antibacterial properties
of some metal complexes. Indian Drugs. 23:24-31, 1985.
11. Rahman M, Athar M, Ahmad N. Complexes of VOSO4 with multidentate schiff
base ligands. J. Chem. Soc. 7:145-154, 1985.
12. Kulkarni YD, Srivastava S, Athar M, Dibenzoyl tellurium diiodide, dibenzoyl
telluride and heterocyclic system derived from them as antibacterial agents.
Indian J. Chem. 26A:57-59, 1986.
13. Athar M, Ahmad N. Synthesis, structure and antibacterial activity of some metal
complexes of furfuraldazine. Indian Drugs. 24(3):132-135, 1986.
16
14. Behari JR, Athar M, Srivastava RC. Lead level in environment and body burden
among workers of lead mines. Indian J. Occup. Health. 29:1-18, 1986.
15. Srivastava RC, Behari JR, Dwivedi PP, Athar M. Evaluation of LD5O of some
polyamino-carboxylic acids used as chelating drugs in metal detoxication. Tox.
Lett. 32:37-40, 1986.
16. Dwivedi PP, Athar M, Chandra S, Hasan SK, Srivastava RC. Effect of chelating
drugs on the removal of nickel from the organs of nickel poisoned rats.
Chemosphere. 1 5:823-831, 1986.
17. Athar M, Ahmad N. Studies on the schiff base complexes of oxovanadium (IV).
Synth. React. Inorg. Met-org. Chem. (USA). 17:723-745, 1987.
18. Shahma, Athar M, Ahmad N Lanthanide complexes with tetradentate schiff
base ligand. Proc. Natl. Acad. Sci. India. 57(A):483-487, 1987.
19. Misra M, Athar M, Chandra S, Hasan SK, Srivastava RC. Effect of chelating
drugs on the pharmacokinetics and metabolic disposition of nickel in poisoned
rats. Chemosphere. 16:259-268, 1987.
20. Athar M, Misra M, Srivastava RC. Evaluation of chelating drugs on the toxicity,
excretion and distribution of nickel in poisoned rats. Fund. Appl. Toxicol. 9:2633, 1987.
21. Athar M, Hasan SK, Srivastava RC., Role of glutathione metabolizing enzymes
in nickel-mediated induction of hepatic glutathione. Res. Comm. Chem. Pathol.
Pharmacol. 57:421-424, 1987.
22. Athar M, Hasan SK, Srivastava RC. Evidence for the involvement of hydroxyl
radicals in nickel mediated enhancement of lipid peroxidation: Implications for
nickel carcinogenesis. Biochem. Biophys. Res. Commun. 147:1276-1281,
1987.
23. Mukhtar H, Athar M, Bickers DR. Cytochrome P-450 dependent metabolism of
testosterone in rat skin. Biochem. Biophys. Res. Commun. 145:749-453,
1987.
24. Rahman M, Athar M, Ahmad N. Synthesis and spectroscopic studies of some
Vanadium (III) complexes. Synth. React. Inorg. Met.-org. Chem. (USA).
18:179-196, 1988.
25. Misra M, Athar M, Hasan SK, Srivastava RC. Comparative effects of chelating
drugs on trace metal and biochemical alterations in rats. Bull. Env. Contam.
Toxicol. 41:172-184, 1988.
26. Misra M, Athar M, Hasan SK, Srivastava RC. Alleviation of nickel-induced
biochemical alterations by chelating agents. Fund. Appl. Toxicol. 11:285-292,
1988.
17
27. Athar M, Mukhtar H, Bickers DR. Differential role of reactive oxygen
intermediates in photofrin-I and photofrin-II mediated enhancement of lipid
peroxidation in epidermal microsomal membrane. J. Invest. Dermatol. 90:662657, 1988.
28. Athar M, Mukhtar H, Elmets CA, Zaim MT, Lloyd JR, Bickers DR. In situ
evidence for the involvement of superoxide anions in cutaneous porphyrin
photosensitization. Biochem. Biophys. Res. Commun. 151:1054-1059, 1988.
29. Srivastava RC, Athar M, Hasan SK, Misra LR. Influence of liver injury on the
metabolic disposition of nickel in rat. Bull. Environ. Contam. Toxicol. 40:439443, 1988.
30. Srivastava RC, Gupta BN, Athar M, Behari JR, Dwivedi RS, Hasan SK, Bharti
RS, Singh A, Misra M, Ray PK. Effect of exposure to toxic gas on population of
Bhopal: Part-III assessment of toxic manifestations in human: Hematological
and biochemical studies. Indian J. Exp. Biol. 26:165-172, 1988.
31. Khan WA, Wang ZY, Athar M, Bickers DR, Mukhtar H. Inhibition of the skin
tumorigenicity
of
(+)-7,8-dihydroxy
9,10-epoxy-7,8,9,10
tetrahydrobenzo(a)pyrene by tannic acid, green tea polyphenols and quercetin
in Sencar mice. Cancer Lett. 42:7-12, 1988.
32. Athar M, Khan WA, Mukhtar H. Effect of dietary tannic acid on epidermal, lung
and forestomach polycyclic aromatic hydrocarbon metabolism and
tumorigenicity. Cancer Res. 49:5784-5788,1989.
33. Athar M, Elmets CA, Bickers DR, Mukhtar H. A novel mechanism for the
generation of superoxide anions in hematoporphyrin derivative-mediated
cutaneous photosensitization. Activation of the xanthine oxidase pathway. J.
Clin. Invest. 83:1137-1143, 1989.
34. Srivastava RC, Srivastava SK, Gupta S, Athar M, Hasan SK. Evaluation of
nickel complexes of bioligands: Effect on distribution profile. Res. Commun.
Chem. Pathol. Pharmacol. 65:253-256, 1989.
35. Wang ZY, Athar M, Khan WA, Bickers DR, Mukhtar H. Antimutagenicity of
green tea polyphenols. Mut. Res. 223:273-285, 1989.
36. Krutmann J, Athar M, Mendel PB, Khan IU, Guyre PM, Mukhtar H, Elmets CA.
Inhibition of the high affinity Fcreceptor (FcRI), on human monocytes by
porphyrin photosensitization is highly specific and mediated by the generation of
superoxide radicals. J. Biol. Chem. 264:11407-11503, 1989.
37. Athar M, Llyod JR, Bickers DR, Mukhtar H. Malignant conversion of radiation
and chemically-induced mouse skin benign tumors by free radical generating
compounds. Carcinogenesis. 10:1841-1845, 1989.
38. Athar M, Mukhtar H, Bickers DR, Khan IU, Kalyanaraman B. Evidence for the
metabolism of tumor promotor organic hydroperoxides into free radicals by
human skin keratinocytes: An ESR spin-trapping study. Carcinogenesis.
18
10:1499-1503, 1989.
39. Athar M, Raza H, Bickers DR, Mukhtar H. Inhibition of benzoyl peroxidemediated tumor promotion in 7,12-dimethylbenz(a)anthracene-initiated skin of
Sencar mice by antioxidants, nordihydroguiaretic acid and diallyl sulphide. J.
Invest. Dermatol. 94:162-165, 1990.
40. Srivastava RC, Kumar A, Srivastava SK, Gupta S, Hasan SK, Athar M. Nickelmediated inhibition in the glutathione-dependent protection against lipid
peroxidation. Biochem. Internatl. 20: 495-501, 1990.
41. Agarwal R, Athar M, Bickers DR, Mukhtar H. Evidence for the involvement of
singlet oxygen in the photodestruction by chloroaluminum phthalocyanine
tetrasulfonate. Biochem. Biophys. Res. Commun. 173:34-41, 1990.
42. Gupta S, Athar M, Behari JR, Srivastava RC. Cadmium-mediated induction of
cellular defence mechanism: A novel example for the development of adaptive
response against a toxicant. Indust. Health. 10:1-10, 1991.
43. Agarwal R, Athar M, Urban SA, Bickers DR, Mukhtar H. Involvement of singlet
oxygen
in
chloroaluminum
phthalocyanine
tetrasulfonate-mediated
photoenhancement of lipid peroxidation in rat epidermal microsomes. Cancer
Lett. 56:125-129, 1991.
44. Athar M, Agarwal R, Wang ZY, Lloyd JR, Bickers DR, Mukhtar H. All-trans
retinoic protects against free radical generating compounds-mediated
conversion of chemically and ultraviolet B radiation-induced skin papillomas to
carcinomas. Carcinogenesis. 12:2325-2329, 1991.
45. Mukhtar H, Agarwal R, Athar M, Lewen RL, Elmets CA, Bickers DR.
Photodynamic therapy of murine skin tumors using Photofrin II. Photodermatol.
Photoimmunol. Photomed. 8:169-175, 1991.
46. Agarwal R, Athar M, Lewen RL, Elmets CA, Bickers DR, Mukhtar H.
Photodynamic therapy of chemically- and ultraviolet radiation-induced murine
skin tumors: comparison of Photofrin II and chloroaluminum phthalocyanine
tetrasulfonate. Photochem. Photobiol. 54:43-50, 1992.
47. Agarwal R, Zaidi SIA, Athar M, Bickers DR, Mukhtar H. Photodynamic effects
of Chloroaluminum Phthalocyanine tetrasulfonate are mediated by singlet
oxygen: In vivo and In vitro studies utilizing hepatic microsomes as model
membrane. Arch. Biochem. Biophys. 284:30-37, 1992.
48. Mahmood N, Khan SJ, Ali S, Athar M, Rahman Q. Asbestos induced oxidative
injury to DNA. Ann. Occup. Hyg. 37:315-319, 1993.
49. Agarwal R,. Khan SG, Athar M, Zaidi SIA, Bickers DR, Mukhtar H. Ras protein
p21 processing enzyme farnesyltransferase in chemical carcinogen-induced
murine skin tumors. Mol. Carcinogenesis. 8:290-298, 1993.
19
50. Mahmood N, Khan SG, Athar M, Rahman Q. Differential role of hydrogen
peroxide and organic peroxides in augmenting asbestos-mediated DNA
damage: Implications for asbestos induced carcinogenesis. Biochem.
Biophys. Res. Commun. 200:687-694, 1994.
51. Sultana S, Iqbal M, Athar M. Crude extract of hepatoprotective plants, Solanum
nigrum and Cichorium intybus inhibit free radical - mediated DNA damage. J.
Ethnopharmacol. 45:189-192, 1995.
52. Anderson A. Robbins HR, Hasan R, Athar M, Mukhtar H, Elmets CA. Metabolic
requirements for induction of contact hypersensitivity to immunotoxic
polyaromatic hydrocarbons. J. Immunol. 155:3530-3537, 1995.
53. Giri U, Sharma SD, Abdulla M, Athar M. Evidence that in situ generated ROS
act as potent stage-I tumor promotor in mouse skin. Biochem. Biophys. Res.
Commun. 209:698-705, 1995.
54. Ahmad I, Krishnamurthi K, Arif JM, Ashquin M, Mahmood N, Athar M and
Rahman Q. Augmentation of Chrysotile-induced Oxidative Stress by BHA in
Mice Lungs. Food Chem. Toxicol. 33:209-215, 1995.
55. Athar M, Iqbal M, Giri U. Novel copper-superoxide dismutase mimics and O2.- mediated damage. Nutrition. 11:559-563, 1995.
56. Iqbal M, Giri U, Athar M. Ferric nitrilotriacetate (Fe-NTA) is a potent hepatic
tumor promoter and acts through the generation of oxidative stress. Biochem.
Biophys. Res. Commun. 212:557-563, 1995.
57. Sharma M, Balani DK, Pillai KK, Hussain SZ, Athar M. Aluminium-mediated
testicular damage: Action through hypothalmic-pituitary axis. Indian J. Toxicol.
3:9-14, 1996.
58. Ali S, Jain SK, Abdulla M, Athar M. Paraquat induced DNA damage by reactive
oxygen species. Biochem. Mol. Biol. Intl. 39:63-67, 1996.
59. Iqbal M, Sharma SD, Rezazadeh H, Hasan N, Abdulla M, Athar M. Glutathione
Metabolizing Enzymes and Oxidative Stress in Ferric Nitrilotriacetate (Fe-NTA)mediated Hepatic Injury. Redox Rep. 2:385-392, 1996.
60. Giri U, Iqbal M, Athar M. Porphyrin-mediated photosensitization has a weak
tumor promoting effect in mouse skin: Possible role of in situ generated reactive
oxygen species. Carcinogenesis. 17:2023-2028, 1996.
61. Athar M, Sharma SD, Iqbal M, Sultana S, Pandeya KB, Tripathi IP.
Coordination of copper polyamine complex with imidazoles potentiates its
superoxide dismutase mimicking activity and abolishes its interaction with
albumin. Biochem. Mol. Biol. Intl. 39:813-821, 1996.
62. Ali S, Abdulla M, Athar M. L-2-Oxothiazolidine-4-carboxylate, an in situ inducer
of glutathione protects against paraquat-mediated pulmonary damage in rat.
Med. Sci. Res. 24:699-701, 1996.
20
63. Iqbal M, Giri U, Giri DK, Athar M. Evidence that Fe-NTA-induced renal
prostaglandin F2 is responsible for hyperplastic response in kidney:
Implications for the role of cyclooxygenase-dependent arachedonic acid
metabolism in renal tumor promotion. Biochem. Mol. Biol. Intl. 42:1115-1124,
1997.
64. Rezazadeh H, Athar M. Evidence that iron-overload promotes 7,12-dimethyl
benz(a)anthracene-induced skin tumorigenesis in mice. Redox Report. 3:303309, 1997.
65. Mahmood N, Khan SG, Athar M, Rahman Q, Mechanism of asbestos-mediated
DNA damage; Role of heme and heme proteins. Environ. Hlth. Perspectives.
105:1109-1112, 1997.
66. Vohora SB, Khanna T, Athar M, Ahmad B. Analgesic activity of bacosine, a new
triterpene isolated from Bacopa monnieri. Fitoterapia. 68:361-365, 1997.
67. Iqbal M, Athar M. Attenuation of iron-nitrilotriacetate (Fe-NTA)-mediated renal
oxidative stress, toxicity and hyperproliferative response by the prophylactic
treatment of rats with garlic oil. Food Chem. Toxicol. 36:485-495, 1998.
68. Athar M, Iqbal M. Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced
renal tumorigenesis in the rat: implications for the involvement of oxidative
stress. Carcinogenesis. 19:1133-1139, 1998.
69. Ahmad I, Fatima M, Athar M, Khan NZ, Raisuddin S. Response of circulating
fish phagocytes to paper mill effluent exposure. Bull. Environ. Contam.
Toxicol. 61:746-753, 1998.
70. Athar M, Iqbal M, Beg MU, Al-Ajmi D, Al-Muzaini S. Airborne dust collected
from Kuwait in 1991-92 augments peroxidation of cellular membrane lipid and
enhances DNA damage. Environ. Intl. 24:205-212, 1998.
71. Rezazadeh
H,
Athar
M.
Iron
overload
augments
7,12dimethylbenz(a)anthracene-initiated and 12-O-tetradecanoyl phorbol 13acetate-promoted skin tumorigenesis. Skin Pharmacol. Appl. Skin Physiol.
11:98-103, 1998.
72. Rezazadeh H, Athar M. Effect of iron overload on the benzoyl peroxide
mediated tumor promotion in mouse skin. Cancer Lett. 126:135-142, 1998.
73. Iqbal M, Rezazadeh H, Ansar S, Athar M. -Tocopherol (Vitamin-E) ameliorates
ferric-nitrilotriacetate (Fe-NTA)-dependent renal proliferative response and
toxicity: diminution of oxidative stress. Hum. Exp. Toxicol. 17:163-171, 1998.
74. Elmets CA, Athar M, Tubesing,KA, Rothaupt D, Xu H, Mukhtar, H. Susceptibility
to the biological effects of polyaromatic hydrocarbons is influenced by genes of
the major histocompatability complex. Proc. Natl. Acad. Sci., USA. 95:1491514919, 1998.
21
75. Hasnain SE, Taneja TK, Sah NK, Mohan M, Pathak N, Sahdev S, Athar M,
Tooley SM, Begum R. In Vitro cultured Spodoptera frugiperda insect cells:
model for oxidative stress-induced apoptosis. J. Biosciences. 24:101-107,
1999.
76. Zhao JF, Zhang YJ, Kubilus YJ, Jin XH, Santella R, Athar M, Zhi Y, Wang ZY,
Bickers DR. Reconstituted 3-dimensional human skin as a novel in vitro
model for studies of carcinogenesis. Biochem. Biophys. Res. Commun.
254:49-53, 1999.
77. Athar M, Giri U. Reactive Oxygen Species generation by photofrin-II-mediated
photosensitization augments TPA-mediated tumor promotion response in
DMBA-initiated mouse skin. Cancer Lett. 135:53-60, 1999.
78. Giri U, Agarwal MK, Khan S, Iqbal M, Athar M. Potassium bromate is a potent
tumor promoter and acts by elaborating oxidative stress. Cancer Lett. 135:
181-188, 1999.
79. Giri U, Iqbal M, Athar M. Copper nitrilotriacetate (Cu-NTA) is a potent inducer
of proliferative response both in liver and kidney but is a complete renal
carcinogen. Intl. J. Oncol. 14:799-806,1999.
80. Bhasin G, Kausar H, Athar M. Ferrochelatase, a novel target for the
photodynamic therapy of cancer. Oncol. Reports. 14:1439-1442, 1999.
81. Iqbal M, Giri U, Giri DK, Alam MS, Athar M. Age-dependent renal accumulation
of 4-hydroxy-2-nonenal (HNE)-modified proteins following parenteral
administration of ferric nitrilotriacetate commensurates with its differential
toxicity: implications for the involvement of HNE-protein adducts in oxidative
stress and carcinogenesis. Arch. Biochem. Biophys. 365:101-112, 1999.
82. Iqbal M, Rehman A, Tirkha P, Athar M. Evidence that Fe-NTA mediate
oxidative stress by down regulating DT-diaphorase activity: Implications for
carcinogenesis. Cancer Lett. 141:151-157, 1999.
83. Ansar S, Iqbal M, Athar M. Nordihydroguairetic acid (NDGA) is a potent
inhibitor of ferric-nitrilotriacetate-mediated hepatic and renal toxicity and renal
tumor promotion in mice. Carcinogenesis. 20:599- 606, 1999.
84. Sah NK, Taneja TK, Pathak N, Begum R, Athar M, Hasnain SE. The
baculovirus antiapoptotic p35 gene also functions via an oxidant-dependent
pathway. Proc. Natl. Acad. Sci., USA. 96:4838-4843, 1999.
85. Iqbal M, Rehman A, Tirkha P, Athar M. Evidence that Fe-NTA mediate oxidative
stress by down regulating DT-diaphorase activity: Implications for
carcinogenesis. Cancer Lett. 141:151-157, 1999.
86. Zhao JF, Zhang YJ, Jin XH, Athar M, Santella M, Bickers DR, Wang ZY.
Green tea protects against PUVA (psoralen plus UVA)-induced photochemical
damage to skin. J. Invest. Dermatol. 113:1070-1075, 1999.
22
87. Zhao JF, Jin XH, Yaping E, Zheng ZS, Zhang YJ, Athar M, DeLeo VA,
Mukhtar H, Bickers DR, Wang ZY. Photoprotective effect of black tea against
UVB-induced Phototoxicity in Skin. Photochem. Photobiol. 70:637-644,
1999.
88. Ahmed S, Rahman A, Athar M, Sultana S. Ellagic acid ameliorates nickelinduced biochemical alterations: Diminution of oxidative stress. Human Exp.
Toxicol. 11:691-698, 1999.
89. Rahman A, Ahmed S, Khan N, Sultana S, Athar M. Glyceryl trinitrate, a nitric
oxide donor, suppresses renal oxidative damage caused by potassium
bromated. Redox Rep. 4:263-269, 1999.
90. Fatima M, Ahmed I, ISayeed I, Athar M, Raisuddin S. Pollution-induced overactivation of phagocytes is concomittantly associated with peroxidative damage
in fish tissues. Aquatic Toxicol. 49:243-250, 2000.
91. Ahmed S, Rahman A, Alam A, Saleem M, Athar M, Sultana S. Evaluation of
the efficacy of Lawsonia alba in the alleviation of carbon tetrachloride-induced
oxidative stress. J. Ethnopharmacol. 69:157-164, 2000.
92. Srivastava RC, Husain MM, Hasan SK, Athar M Green tea polyphenols and
tannic acid act as potent inhibitors of phorbol ester-induced nitric oxide
generation in rat hepatocytes independent of their antioxidant properties.
Cancer Lett. 153:1-5, 2000.
93. Sharma N, Trikha P, Athar M, Raisuddin S. In vitro inhibition of carcinogeninduced mutagenicity by Cassia occidentalis and Emblica officinalis. Drug
Chem. Toxicol. 23:477-484, 2000.
94. Sharma N, Trikha P, Athar M, Raisuddin S. Inhibitory effect of Emblica officinalis
on the in vivo clastogenicity of benzo[alpyrene and cyclophosphamide in mice.
Human Exp. Toxicol. 19:377-384, 2000.
95. Ahmad I, Hamid T, Fatima M, Chand HS, Jain SK, Athar M, Raisuddin, S.
Induction of hepatic antioxidants in freshwater catfish (Channa punctatus
Bloch) is marker of paper mill effluent exposure. Biochem. Biophys. Acta.
1519:37-48, 2000.
96. Athar M, Kim AL, Ahmad N, Mukhtar H, Gautier J, Bickers DR. Mechanism of
ultraviolet B-induced cell cycle arrest in G2/M phase in immortalized skin
keratinocytes with defective p53. Biophys. Biochem. Res. Commun. 277:
107-111, 2000.
97. Ahmed S, Rahman A, Mathur M, Athar M, Sultana S. Anti-tumor promoting
potential
of
Asteracantha
longifolia
against
experimental
hepatocarcinogenesis in rats. Food Chem. Toxicol. 39:19-28, 2001.
98. Rezazadeh H, Nayebi AR, Athar M. Effect of iron-dextran on 7,12dimethylbenz(a) anthracene-initiated and croton oil-promoted cutaneous
tumorigenesis in normal and pregnant mice. Hum. Exp. Toxicol. 20: 47123
476, 2001.
99. Athar M, An KP, Morel KD, Kim AL, Aszterbaum M, Longley J, Epstein Jr.
EH, Bickers DR. Ultraviolet B (UVB)-Induced COX-2 Expression in Murine
Skin: An Immunohistochemical Study. Biophys. Biochem. Res. Commun.
280:1042-1047, 2001.
100. Liu SX, Athar M, Lippai I, Waldren CA, Hei TK. Induction of oxyradicals by
arsenic: Implication for mechanism of genotoxicity. Proc. Nalt. Acad. Sci.
USA. 98:1643-1648, 2001.
101. Trikha P, Sharma N, Athar M. Nitroglycerin: A NO donor inhibits TPAmediated tumor promotion in murine skin. Carcinogenesis. 22:1207-1211,
2001.
102. Sharma N, Trikha P, Athar M, Raisuddin S. Inhibition of benzo[alpyreneand cyclophosphamide-induced mutagenicity by Cinnamomum cassia. Mut.
Res. 480:179-188, 2001.
103. Hebert JL, Khugyani F, Athar M, Kopelovich L, Epstein Jr. EH, Aszterbaum
M. Chemoprevention of Basal Cell Carcinomas in the ptc1(+/-) Mouse Green and Black Tea. Skin Pharmacol. Appl. Skin Physiol. 14:358-362,
2001.
104. Hsu S, Lewis JB, Borke LJ, Singh B, Dickinson DP, Caughman GB, Athar
M, Drake L, Aiken AC, Huynh AT, Das BR, Osaki T, Schuster GS.
Chemopreventive effects of green tea polyphenols correlate with reversible
induction of p57 expression. Anticancer Res. 21:3743-3748, 2001.
105. Kim AL, Athar M, Bickers DR, Gautier J. Stage-specific alterations of cyclin
expression during ultraviolet B-induced murine skin tumor development.
Photochem. Photobiol. 75:58-67, 2002.
106. Kim AL, Athar M, Bickers DR, Gautier J. Ultraviolet B (UVB)-induced G1
arrest is mediated by down regulation of cyclin-dependent kinase 4 (cdk4) in
transformed keratinocytes lacking functional p53. J. Invest. Dermatol. 118:
818-824, 2002.
107. Bhasin G, Kauser H, Athar M. Low iron state is associated with reduced
tumor promotion in a two-stage mouse skin carcinogenesis model. Food
Chem. Toxicol. 40:1105-1111, 2002.
108. Bhasin G, Kauser H, Athar M. Iron augments stage-I and stage-II tumor
promotion in murine skin. Cancer Lett. 183:113-122, 2002.
109. An KP, Athar M, Tang X, Katiyar SK, Russo J, Beech J, Aszterbaum M,
Kopelovich L, Epstein Jr. EH, Mukhtar H, Bickers DR. Cyclooxygenase-2
Expression in Murine and Human Non-melanoma Skin Cancers: Implications
for Therapeutic Apporoaches. Photochem. Photobiol. 76:73-80, 2002.
24
110. Bhasin G, Kauser H, Athar M. Proroporphyn-IX accumulation and
cutaneous tumor regression in mice using a ferrochelatase inhibitor. Cancer
Lett. 187:9-16, 2002.
111. Kim AL, Gautier J, Bickers DR. Athar M. Reduced cyclin D1 proteolysis as
a putative mechanism for cyclin D1 overexpression in UVB-induced murine
squamous cell carcinomas. Biophys. Biochem. Res. Commun. 298:377393, 2002.
112. Hsu S, Yu F, Lewis J, Singh B, Borke J, Osaki T, Athar M, Schuster G.
Induction of p57 is required for cell survival when exposed to green tea
polyphenols. Anticancer Res. 22:4115-4120, 2002.
113. Bhasin G, Kausar H, Alam MS, Athar M. Progressive iron-overload
enhances chemically mediated tumor promotion in murine skin. Arch.
Biochem. Biophys. 409: 262-273, 2003.
114. Hsu S, Lewis J, Singh B, Schoenlein, Osaki T, Athar M, Porter AG,
Schuster GS. Green tea polyphenol targets the mitochondria in tumor cells
inducing caspase 3-dependent apoptosis. Anticancer Res. 23:1533-1540.
2003.
115. Bhasin G, Kauser H, Zargar MA, Athar M, Palm oil alleviates 12-Otetradecanoyl-13-acetate-induced tumor promotion response in murine skin.
Cancer Lett. 192:151-160, 2003.
116. Mohan M, Taneja TK, Sahdev S, Mohareer K, Begum R, Athar M, Sah
NK, Hasnain SE. Antioxidants prevent UV-induced apoptosis by inhibiting
mitochondrial cytochrome c release and caspase activation in Spodoptera
frugiperda (Sf9) cells. Cell Biol. Int. 27:483-490, 2003.
117. Sahdev S, Taneja TK, Mohan M, Sah NK, Khar AK, Hasnain SE, Athar M.
Baculoviral p35 inhibits oxidant-induced activation of mitochondrial apoptotic
pathway. Biophys. Biochem. Res. Commun. 307:483-490, 2003.
118. Rahman A, Ahmed S, Vasenwala SM, Athar M. Glyceryl trinitrate, a nitric
oxide donor abrogates ferric nitrilotriacetate-induced oxidative stress and
renal damage. Arch. Biochem. Biophys. 418:71-79, 2003.
119. Kaur G, Hamid H, Ali A, Alam MS, Athar M. Antiinflammatory evaluation
of alcoholic extract of galls of Quercus infectoria. J Ethnopharmacol. 90(23):285-292, 2004.
120. Kaur G, Alam MS, Athar M. Nimbidin suppresses functions of
macrophages and neutrophils: relevance to its antiinflammatory mechanisms.
Phytother. Res. 18(5):419-24, 2004.
121. Bhasin G, Kauser H, and Athar M. Free radical generating agents lead to
the rapid progression of benign skin tumors to carcinoma in iron-overloaded
mice. Arch. Toxicol. 78:283-289, 2004.
25
122. Bhasin G,. Kauser H, Athar M. Low iron diet retards 12- O-tetradecanoyl
phorbol-13-acetate-mediated tumor promotion in murine skin. Arch Toxicol.
78:139-146, 2004.
123. Agarwal MK, Agarwal ML, Athar M, Gupta S. Tocotrienol-Rich Fraction of
Palm Oil Activates p53, Modulates Bax/Bcl2 Ratio and Induces Apoptosis
Independent of Cell Cycle Association. Cell Cycle. 3:205-211, 2004.
124. Athar M, An KP, Tang X, Murel KD, Kim AL, Kopelovich L, Bickers DR.
Photoprotective effects of sulindac against ultraviolet B-induced phototoxicity
in the skin of SKH-1 hairless mice. Toxicol. Appl. Pharmacol. 195:370-378,
2004.
125. Yamamoto T, Lewis J, Wataha J, Dickinson D, Singh B, Bollag WB, Ueta
E, Osaki T, Athar M, Schuster G, Hsu S. Roles of catalase and hydrogen
peroxide in green tea polyphenol-induced chemopreventive effects. J.
Pharmacol. Exp. Ther. 308:317-23, 2004.
126. Tang X, Kim AL, Feith DJ, Pegg AE, Russo J, Zhang H, Aszterbaum M,
Kopelovich L, Epstein Jr. EH, Bickers DR, M. Athar. Ornithine Decarboxylase
is a Target for Chemoprevention of basal and squamous cell carcinomas in
Ptch1+/- Mice. J. Clin. Invest. 113:867-875, 2004.
127. Vogt A, Chuang PT, Herbert J, Hwang J, Lu Y, Kopelovich L, Athar M,
Bickers DR, Epstein Jr. EH. Immunoprevention of Basal Cell Carcinomas
with Recombinant Hedgehog-interacting Protein. J. Exp. Med. 199:743-752,
2004.
128. Vogt A, Chuang PT, Herbert J, Hwang J, Lu Y, Kopelovich L, Athar M,
Bickers DR, Epstein Jr. EH. Topical Tazarotene Chemoprevention Reduces
Basal Cell Carcinoma Number and Size in Ptch1+/- Mice Exposed to
Ultraviolet Radiation or Ionizing Radiation. Cancer Res. 64:4385-4389,
2004.
129. Athar M, Li C, Tang X, Chi S, Zhang X, Kim AL, Tyring SK, Kopelovich L,
Hebert J, Epstein EH Jr, Bickers DR, Xie J., Inhibition of smoothened
signaling prevents ultraviolet B-induced basal cell carcinomas through
regulation of Fas expression and apoptosis. Cancer Res. 64:7545-7552,
2004.
130. Agarwal MK, Iqbal M, Athar M. Inhibitory effect of 18beta-glycyrrhetinic
acid on 12-O-tetradecanoyl phorbol-13-acetate-induced cutaneous oxidative
stress and tumor promotion in mice. Redox Rep. 10:151-157, 2005.
131. *Hamid H, Kaur G, Abdullah ST, Ali M, Athar M, Alam M. Two new
compounds from the galls of Quercus infectoria with nitric oxide and
superoxide inhibiting ability. Pharmaceutical Biol. 43(4):317-323, 2005.
132. Agarwal MK, Iqbal M, Athar M. Vitamin E inhibits hepatic oxidative stress,
toxicity and hyperproliferation in rats treated with the renal carcinogen ferric
nitrilotriacetate. Redox Rep. 10:62-70, 2005.
26
133. Paul B, Kim AL, Athar M, Gilmour S. Elevated Polyamines Lead to the
Selective Induction of Apoptosis and Inhibition of Tumorigenesis by the Green
Tea Polyphenol (-)-Epigallocatechin-3-Gallate (EGCG). Carcinogenesis. 26:
119-124, 2005.
134. Liu SX, Davidson MM, Tang X, Athar M, Ivanov V, Hei TK. MItochondrial
damage mediates genotoxicity of arsenic in mammalian cells. Cancer Res.
65:3236-3242, 2005.
135. *Kim AL, Labasi J, Zhu Y, Tang X, McClure K, Gabel CA, Athar M, Bickers
DR. Role of p38 MAPK and COX-2 in UVB-induced inflammatory responses
in the skin of SKH-1 hairless mice. J. Invest. Dermatol. 124:1318-1325,
2005.
136. *Lee J, Kim AL, Bickers DR, Athar M. Differential expression of E
prostanoid (EP) receptors in Squamous Cell and Basal Cell Carcinomas of
human and murine skin. J. Invest. Dermatol. 125:818-825, 2005.
137. Kaur G, Jabbar Z, Athar M, Alam MS. Punica granatum (pomegranate)
flower extract possesses potent antioxidant activity and abrogates Fe-NTA
induced hepatotoxicity in mice. Food Chem. Toxicol. 44:984-993, 2006.
138. Alam MS, Kaur G, Jabbar Z, Javed K, Athar M. Evaluation of antioxidant
activity of Salix caprea flowers. Phytother. Res. 20(6):479-483 (2006).
139. Khan B, Ahmad SF, Bani S, Kaul A, Suri KA, Satti NK, Athar M, Qazi GN.
Augmentation and proliferation of T lymphocytes and Th-1 cytokines by
Withania somnifera in stressed mice. Int. Immunopharmacol. 6(9):1394403, 2006.
140. Kaur G, Alam MS, Jabbar Z, Javed K, Athar M. Evaluation of antioxidant
activity of Cassia siamea flowers. J. Ethnopharmacol. 108:340-348, 2006.
141. Parvez S, Tabassum H, Rehman H, Banerjee BD, Athar M, Raisuddin S.
Catechin prevents tamoxifen-induced oxidative stress and biochemical
perturbations in mice. Toxicology. 225:109-118, 2006.
142. Kim AL, Zhu Y, Zhu H, Kopelovich L, Bickers DR, Athar M. Resveratrol
inhibits proliferation of human epidermoid carcinoma A431 cells by
modulating MEK1 and AP-1 signaling pathways. Exp. Dermatol. 15:538546, 2006.
143. Lebedeva IV, Sarkar D, Su ZZ, Gopalkrishnan RV, Athar M, Randolph A,
Valerie K, Dent P, Fisher PB. Molecular Target-Based Therapy of Pancreatic
Cancer. Cancer Res. 66:2403-2413, 2006.
144. SarwarAM, Kaur G, Jabbar Z, Javed K, Athar M. Eruca sativa seeds
possess antioxidant activity and exert a protective effect on mercuric chloride
induced renal toxicity. Food Chem. Toxicol. 45:910-20, 2007.
27
145. Kaur G, Lone IA, Athar M, Alam MS. Protective effect of Didymocarpus
pedicellata on ferric nitrilotriacetate (Fe-NTA) induced renal oxidative stress
and hyperproliferative response. Chem. Biol. Interact. 165:33-44, 2007.
146. Lone IA, Kaur G, Athar M, Alam MS. Protective effect of Rumex patientia
roots on ferric nitrilotriacetate (Fe-NTA) induced hepatic oxidative stress and
tumor promotion response. Food Chem. Toxicol. 45:1821-9, 2007.
147. Agarwal MK, Iqbal M, Athar M. Garlic oil ameliorates ferric nitrilotriacetate
(Fe-NTA)-induced damage and tumor promotion: Implications for cancer
prevention. Food Chem. Toxicol. 45(9):1634-40, 2007.
148. Arif E, Vibhuti A, Alam P, Deepak D, Singh B, Athar M, Pasha MA.
Association of CYP2E1 and NAT2 gene polymorphisms with chronic
obstructive pulmonary disease. Clin. Chim. Acta. 382(1-2):37-42, 2007.
149. Arif E, Ahsan A, Vibhuti A, Rajput C, Deepak D, Athar M, Singh B, Pasha
MA. Endothelial nitric oxide synthase gene variants contribute to oxidative
stress in COPD. Biochem. Biophys. Res. Commun. 361:182-8, 2007.
150. Sultana Y, Kohli K, Athar M, Khar RK, Aqil M. Effect of pre-treatment of
almond oil on ultraviolet B-induced cutaneous photoaging in mice. J. Cosmet.
Dermatol. 6(1):14-9, 2007.
151. Tang X, Zhu Y, Han L, Kim AL, Kopelovich L, Bickers DR, Athar M., CP31398 Restores Mutant p53 Tumor Suppressor Function and Inhibits UVBinduced Skin Carcinogenesis in Mice. J. Clin. Invest. 117:3753-3764, 2007.
152. Rahman S, Bhatia K, Khan AQ, Kaur M, Ahmad F, Rashid H, Athar M,
Islam F, Raisuddin S. Topically applied vitamin E prevents massive
cutaneous inflammatory and oxidative stress responses induced by double
application of 12-O-tetradecanoylphorbol-13-acetate (TPA) in mice. Chem.Biol. Interact. 172:195-205, 2008.
153. Alam MS, Kaur G, Ali A, Hamid H, Ali M, Athar M., Two new bioactive
oleanane triterpene glycosides from Terminalia arjuna. Nat. Prod. Res. 22:
1285-94, 2008.
154. Rehman S, Shawl AS, Verma V, Kour A, Athar M, Andrabi R, Sultan P,
Qazi GN. An endophytic Neurospora sp. from Nothapodytes foetida
producing camptothecin. Prikl. Biokhim. Mikrobiol. 44:225-231, 2008.
155. Kaur G, Athar M, Alam MS. Quercus infectoria galls possess antioxidant
activity and abrogates oxidative stress-induced functional alterations in
murine macrophages. Chem.-Biol. Interact. 171:272-82, 2008.
156. Tang X, Kim AL, Kopelovich L, Bickers DR, Athar M., Cyclooxygenase-2
inhibitor nimesulide blocks ultraviolet B-induced photocarcinogenesis in SKH1 hairless mice. Photochem. Photobiol. 84:522-527, 2008.
28
157. Lebedeva I, Su ZZ, Vozhilla N, Chatman L, Sarkar D, Dent P, Athar M,
Fisher PB. Chemoprevention by perillyl alcohol coupled with viral gene
therapy reduces pancreatic cancer pathogenesis. Mol. Cancer Therap. 7:
2042-2050, 2008.
158. Lebedeva I, Su ZZ, Vozhilla N, Chatman L, Sarkar D, Athar M, Fisher, PB.
Mechanism of in vitro pancreatic cancer cell growth inhibition by mda-7/IL-24
and perillyl alcohol. Cancer Res. 68:7439-7447, 2008.
159. Sanjay P, Kim HK, Thrash CJ, Cox MA, Mantena SK, Wu J-H, Athar M,
Katiyar SK, Elmets CA, Timares L. A critical role for the proapoptotic protein
Bid in UV-induced immune suppression and cutaneous apoptosis., J.
Immunol. 181:3077-3088, 2008.
160. Kim HK, Zhang H, Li H, Wu T, Swisher S, He D, Wu L, Athar M, Elmets
CA, Xu X, Xu H. Slit2 inhibits the growth and metastasis of fibrosarcoma and
squamous cell carcinoma. Neoplasia. 10:1411-1420, 2008.
161. Kaur G, Lone IA, Athar M, Alam MS. Guilandina bonduc L. possesses
antioxidant activity and precludes Ferric Nitrilotriacetate (Fe-NTA) induced
renal toxicity and tumor promotion response. J. Environ. Pathol. Toxicol
Oncol. 28:163-75, 2009.
162. Chaudhary SC, Alam MS, Siddiqui MS, Athar M. Chemopreventive effect
of farnesol on DMBA/TPA-induced skin tumorigenesis: Involvement of
inflammation, Ras-ERK pathway and apoptosis. Life Sci. 85:196-205, 2009.
163. Kaur G, Athar M, Alam MS. Dietary supplementation of silymarin protects
against chemically induced nephrotoxicity, inflammation and renal tumor
promotion response. Invest. New Drugs. 28(5):703-13, 2009.
164. Kaur G, Alam MS, Athar M. Cumene Hydroperoxide Debilitates
Macrophage Physiology by Inducing Oxidative Stress: Possible Protection by
alpha-Tocopherol. Chem.-Biol. Interact. 179:94-102, 2009.
165. Chaudhary SC, Alam MS, Siddiqu MS, Athar M. Perillyl alcohol attenuates
Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis,
Chem.-Biol. Interact. 179:145-153, 2009.
166. Shaik SS, Soltau TD, Chaturvedi G, Totapally B, Hagood JS, Andrews
WW, Athar M, Killingsworth C, Patel RP, Fallon MB, Maheshwari A. Lowintensity Shear Stress Increases Endothelial ELR+ CXC Chemokine
Production via a FAK-p38β-NFκB pathway. J. Biol. Chem. 284:5945-5955,
2009.
167. Kaur G, Athar M, Alam MS. Eugenol precludes cutaneous chemical
carcinogenesis in mouse by preventing oxidative stress and inflammation and
by inducing apoptosis. Mol. Carcinogenesis. 49:290-301, 2010.
29
168. Tang JY, Aszterbaum M, Athar M, Barsanti F, Cappola C, Estevez N,
Hebert J, Hwang J, Khaimskiy Y, Kim A, Lu Y, So PL, Tang X, Kohn MA,
McCulloch CE, Kopelovich L, Bickers DR, Epstein EH Jr. Basal cell
carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in
genetically predisposed PTCH1+/- humans and mice. Cancer Prev. Res.
(Phila Pa). 3:25-34, 2010.
169. Xu J, Timares L, Heilpern C, Weng Z, Li C, Xu H, Pressey JG, Elmets CA,
Kopelovich L, Athar M. Targeting wild-type and mutant p53 with small
molecule CP-31398 blocks the growth of rhabdomyosarcoma by inducing
reactive oxygen species-dependent apoptosis. Cancer Res. 70:6566-76,
2010.
170. Kim KH, Back JH, Zhu Y, Arbesman J, Athar M, Kopelovich L, Kim AL,
Bickers DR. Resveratrol targets transforming growth factor-β2 signaling to
block UV-induced tumor progression. J. Invest. Dermatol. 131:195-202,
2011.
171. Maheshwari A, Kelly DR, Nicola T, Ambalavanan N, Jain SK, MurphyUllrich, J, Athar M, Shimamura M, Bhandari V, Aprahamian C, Dimmitt RA,
Serra R, Ohis RK. TGF- β(2) suppresses cytokine production and mucosal
inflammatory responses in the developing intestine. Gastroenterology, 140:
242-53, 2011.
172. Byekova YA, Herrmann JL, Xu J, Elmets CA, Athar M. Liver kinase B1
(LKB1) in the pathogenesis of UVB-induced murine basal cell carcinoma.
Arch Biochem Biophys. 508:204-211, 2011 Jan 25. [Epub ahead of print]
PubMed PMID: 21272562.
173. Croyle MJ, Lehman JM, O'Connor AK, Wong SY, Malarkey EB, Iribarne D,
Dowdle WE, Schoeb TR, Verney ZM, Athar M, Michaud EJ, Reiter JF, and
Yoder BK. Role of Epidermal Primary Cilia in the Homeostasis of Skin and
Hair Follicles. Development, Mar 23 [Epub ahead of print], 2011.
174. Walsh SB, Xu J, Xu H, Kurundkar AR, Maheshwari A, Grizzle WE,
Timares L, Huang CC, Kopelovich L, Elmets CA, Athar M. Cyclosporine A
Mediates Pathogenesis of Aggressive Cutaneous Squamous Cell Carcinoma
by Augmenting Epithelial-Mesenchymal Transition: Role of TGFβ
Pathway. Mol. Carcinogenesis. 50: In press, 2011.
175. Xu J, Walsh SB, Verney ZM, Kopelovich L, Elmets CA, Athar M.
Procarcinogenic Effects of Cyclosporine A are Mediated through the
Activation of TAK1/TAB1 Signaling Pathway. Biochem. Biophys. Res.
Commun. 406: In press, 2011.
176. Back JH, Rezvani HR, Zhu Y, Guyonnet-Duperat V, Athar M, Ratner D,
Kim AL. Cancer cell survival following DNA damage-mediated premature
senescence is regulated by mammalian target of rapamycin (mTOR)dependent inhibition of sirtuin 1. J Biol Chem. Apr 6. [Epub ahead of print],
2011.
30
Reviews, Book Chapters and Editorials
1 Athar M. Fundamentals of radioactivity, radiation and their effects on life, In
the proceedings of the workshop on safety aspects in the research
applications of radioisotopes, Industrial Toxicology Research Centre,
Lucknow, Publication. 15-25, 1986,15-25.
2 Athar M (As a team member), Bhopal Disaster. A follow up study - phase-I
and II. Industrial Toxicology Research Centre. Lucknow, Publication, 1987.
(A classified document).
3 Athar M, Elmets CA, Zaim MT, Lloyd JR, Bickers DR, Mukhtar H:
Involvement
of
superoxide
anions
in
cutaneous
porphyrin
photosensitization: an in vivo study, in New Directions in Photodynamic
Therapy, DC Neckers (ed) SPIE-The Int Soc Opt Eng vol. 847:193-200,
1988.
4 Mukhtar H, Athar M. Dietary anticarcinogens and cancer prevention. Cleve.
Clin. J. Med. 55:507-508, 1988.
5 Mukhtar H, Merk, Athar M. Skin chemical carcinogenesis. Clin. Dermatol.
7:1-10, 1989.
6 Athar M (As a team member), Bhopal Disaster. A follow up study - Phase III.
Industrial Toxicology Research Centre, Lucknow Publication, 1989.
7 Khan WA, Wang ZY, Das M, Athar M, DR. Bickers DR, Mukhtar H..
Protection against polycyclic aromatic hydrocarbon induced skin
tumorigenesis by tannic acid: Mechanistic study. In Polynuclear Aromatic
Hydrocarbons. Vol. XI, M. Cooke and A.J. Dennis, (eds) Battelle Press,
Columbus, USA., 481-94, 1991
8 Athar M, Srivastava RC, Hasan SK, Srivastava SK.
Biochemical
implications of nickel carcinogenesis, In `Biomembrane in Healths and
Diseases'. A.M. Kidwai, R.K. Upreiti and P.K. Ray, (eds). Today and
Tomorrow Pub., New Delhi, India., 1:253-258, 1991.
9 Athar M. Agarwal R, Bickers DR, Mukhtar H. Pharmacological aspects of
reactive oxygen species in skin. In Pharmacology of Skin. CRC-Press,
Florida, USA,. 269-282, 1992.
10 Abdulla M, .Athar M. Mineral Water. In Encyclopedia of Food Science,
Food Technology and Nutrition, Academic Press, San Diego, U.S.A.,
3116-3119, 1993.
11 Athar M, Abdulla M, Sultana S. Free Radicals and trace elements. J. Trace
Elements Exp. Med. 6:65-73, 1993.
12 Sultana S, Ali S, Ali B, Athar M. Role of reactive oxygen species in
cutaneous chemical carcinogenesis. Int. J. Toxicol. Occup. Environ. Health.
31
2:27-33, 1993.
13 Rahman Q, Athar M. Asbestos-induced carcinogenesis: An Update. Adv.
Biosci. 75-78, 1994.
14 Rahman Q, Mahmood N, Khan SG, Athar M. Augmentation in the differential
oxidative DNA-damage by asbestos in presence of H2O2 and organic
peroxide/hydroperoxide. In Cellular and Molecular Effects of Mineral and
Synthetic Dusts and Fibres. J.M.G. Davis & M.C. Jaurand, (eds.),
Springer, New York, NATO ASI Series H, 85:171-181, 1994.
15 Abdulla M, Athar M. Metal ions levels in acute infections. In `Hand book on
Metal-Ligand Interaction In Biological fluids'. G. Berthon (Ed.) Marcel
Dekker, New York, U.S.A., 2:1093- 1096, 1995.
16 Kishore K, Athar M, Seth SD, Singh U, Siddiqui HH, Khan HA. Trace
elements in arthritis, In Trace and Toxic elements in Nutrition and Health.
M Abdulla, SB Vohora, M Athar, (Eds.), Wiley Eastern Limited, New Delhi,
INDIA. 67-70,1995.
17 Kishore K, Singh U, Athar M, Seth SD, Khan HA. Status of trace elements in
Indian patients of Osteoarthritis. In Trace and Toxic elements in Nutrition
and Health. M Abdulla, SB Vohora, M Athar (Eds.), Wiley Eastern
Limited, New Delhi, INDIA. 71-72, 1995.
18 Athar M, Sharma SD, Iqbal M, Ali B, Sultana S, Khanna T, Pandeya KB,
Tripathi IP. Superoxide dismutase mimics abrogate O2.--mediated damage
to biological systems. In Trace and Toxic elements in Nutrition and
Health. M Abdulla, SB Vohora, M Athar (Eds), Wiley Eastern Limited, New
Delhi, INDIA. 203-209, 1995.
19 Ali B, Badar GN, Khanna P, Athar M, Sharma SD, Sultana S. Bioactivation
of thiacetazone, an antitubercular drug, to a toxic N-deacetylated metabolite,
In Elements and Liver. HM Said, MA Rehman, M Abdulla, SB Vohora, M.
Athar (Eds.), Hamdard Foundation, 85-95,1996.
20 Athar M, Husain SZ, Hasan N. Carcinogen and drug metabolism and the
liver: In Liver and Environmental Xenobiotics. SVS Rana, K Taketa
(Eds), Narosa-Springer Verlag, New Delhi, 19-30,1997.
21 Athar M. Food contaminants and health hazards: In Poison Information
and Control. SB. Lall (Ed.), Narosa-Springer Verlag, New Delhi, 184-200,
1998.
22 Athar M, Ali S. Metal ions and oxidative stress in animal model system: In
Heavy Metals: Pollution, Toxication and Chelation. PP. Sood (Eds.),
Venus Publishers, New Delhi, 223-240, 1998.
23 Giri U, Kausar H, Athar M. Free radicals and oxidative stress in biological
system. Environment & Health, 1-16, 1999.
32
24 Rahman Q, Abidi P, Afaq F, Schiffmann D, Mossman BT, Kamp DW,
Athar M. Glutathione redox system in oxidative lung injury. Crit.
Rev.Toxicol. 29:543-568,1999.
25 Begum R, Taneja TK, Mohan M, Pathak N, Sah NK, Athar M, Hasnain SE.
The control and execution of program cell death, In F Juelich (Ed.), Recent
aspects of cellular & applied radiation biology. Semin. Int. BUR. 30:2345, 1999.
26 Raisuddin S, Sharma N, Trikha P, Athar M. Mutagens and carcinogens in
the environment and food: Chemoprevention by herbal and dietary minor
constituents. In Environmental Stress: Hazards and Management. M
Iqbal, PS Srivastava, TP Siddiqui (Eds.), Narosa, New Delhi, India. 225-240,
2000.
27 Bickers DR, Athar M. Novel approaches to chemoprevention of skin
cancer. J. Dermatol. 27: 691-695, 2000.
28 Athar M. Oxidative stress and experimental carcinogenesis. Indian J. Exp.
Biol. 40:656-667, 2002.
29 Hasnain SE, Begum R, Ramaiah KV, Sahdev S, Shajil EM, Taneja TK,.
Mohan M, Athar M, Sah NK, Krishnaveni M. Host-pathogen interactions
during apoptosis. J. Biosci. 28:349-58, 2003.
30 Lee K, Mukhtar H, Bickers DR, Kopelovich L, Athar M. Cyclooxygenases
in the skin: Pharmacological and toxicological implications. Toxicol.
Appl. Pharmacol. 192:294-306, 2003.
31 Athar M, Tang X, Lee JL, Kopelovich L, Kim AL. Hedgehog signaling in
skin development and cancer. Exp. Dermatol. 15:667-677, 2006.
32 Bickers DR, Athar M. Oxidative stress in the pathogenesis of skin
diseases. J. Invest. Dermatol. 126:2565-2575, 2006.
33 Athar M, Back JH, Tang X, Kim KH, Kopelovich L, Bickers DR, Kim AL.,
Resveratrol: A review of preclinical studies for human cancer prevention.
Toxicol. Appl. Pharmacol. 224(3):274-283, 2007.
34 Athar M, Back JH, Kopelovich L, Bickers DR, Kim AL Multiple molecular
Targets of Resveratrol: Anti-carcinogenic Mechanisms. Arch. Biochem.
Biophys. 486:95-102, 2009.
35 Hsieh, Y-C, Athar M, IChaudry IH. When apoptosis meets autophagy:
deciding cell fate after trauma and sepsis. Trends Mol. Med. 15:129-138,
2009.
36 Elmets CA, Athar M. Targeting ornithine decarboxylase for the prevention of
nonmelanoma skin cancer in humans. Cancer Prev. Res. (Phila Pa). 3:811, 2010.
33
37 Holzer AM, Athar M, Elmets CA. The other end of the rainbow: infrared
and skin. J. Invest. Dermatol. 130:1496-1499, 2010.
38 Athar M, Kim AL, Kopelovich L, Elmets CA, Bickers DR. Skin Diseases:
Role of Reactive Oxygen and Nitrogen, Chapter 51 in ‘Principles of Free
Radical Biomedicine’ Nova Science Publishers, Inc. Hauppauge, NY,
USA, 2011.
39 Herrmann JL, Byekova YA, Elmets CA, Athar M. LKB1 in the Pathogenesis
of Skin and Other Epithelial Cancers Cancer Lett. In Press, 2011.
40 Athar M, Walsh SB, Kopelovich MD, Elmets CA. Pathogenesis of
nonmelanoma skin cancers in organ transplant recipients. Arch.
Biochem. Biophys. 508:159-163, 2011 Jan 11. [Epub ahead of print]
PubMed PMID: 21232524.
41 Cafardi JA, Shafi R, Athar M, Elmets CA. Prospects for Skin Cancer
Treatment and Prevention: The Potential Contribution of an Engineered
Virus. J. Invest. Dermatol. 131: 559-561, 2011.
42 Athar M, Elmets CA, Kopelovich L. Pharmacological activation of p53 in
cancer cells. Curr Pharm Des. In press, 2011.
43 Athar M Kopelovich L. Rapamycin Acts as an Effective Chemopreventive
Agent in Skin: Role of mTORC1 Inhibition. Cancer Prev. Res. (Phila Pa).
4: In press, 2011.
Patents
The AcMNPV baculovirus p35 Gene protects against oxidative stressinduced apoptosis (Patent No.: 2213/DEL/97 filed on July 8, 1997).
34
Abstracts
1. Athar M, Hasan SK, Srivastava RC. Nickel-induced hepatic lipid peroxidation:
Mechanistic study. Fed. Proc. 46:556, 1987.
2. Athar M, Mukhtar H, Bickers DR. Photofrin-I and photofrin-II mediated
enhancement of lipid peroxidation in epidermal microsomes. J. Invest.
Dermatol. 88:475, 1987. Clin. Res. 35, 667A (1987).
3. Mukhtar H, Athar M, Bik DP, Bickers DR. Cytochrome P-450 dependent
metabolism of testosterone in rat skin. Clin. Res. 35:924A, 1987.
4. Athar M, Khan WA, Mukhtar H. Effect of dietary tannic acid on epidermal, lung
and forestomach polycyclic aromatic hydrocarbon metabolism and
tumorigenicity. FASEB J. 2:A862, 1988.
5. Bik DP, Das M, Khan WA, Wang ZY, Athar M, Bickers DR, Mukhtar H.
Protection against polycyclic aromatic hydrocarbon and N-methyl-N-nitrosoureainduced skin tumorigenesis in mice by naturally occurring plant phenols.
FASEB J. 2:A843, 1988.
6. Athar M, Elmets CA, Zaim MT, Bickers DR, Mukhtar H. Activation of xanthine
oxidase pathway leading to generation of superoxide anions as a mechanism
for porphyrin-mediated cutaneous photosensitization. J. Invest. Dermatol. 90:
644,1988. Clin. Res. 36:630A,1988.
7. Bickers DR, Athar M, Mukhtar H. Metal-substituted phthalocyanines: Novel
photosensitizers for use in photoradiation therapy of cutaneous cancer. Clin.
Res. 36:549A, 1988.
8. Krutmann J, Athar M, Mendel D, Khan IU, Guyre PM, Mukhtar H, Elmets CA.
Inactivation of the ligand binding site of the human monocyte FcRI receptor
following porphyrin photosensitization. Clin. Res. 36:377A, 1988.
9. Bickers DR, Athar M, Mukhtar H. Protection against active oxygen species.
Skin Pharmacol. 1:49, 1988.
10. Mukhtar H, Athar M, Elmets CA, Zaim MT, Bickers DR. Mechanism of
photofrin-II induced skin photosensitization: Involvement of the xanthine oxidase
pathway. Skin Pharmacol. 1: 58, 1988.
11. Athar M, Mukhtar H, Bickers DR. Photodestruction of microsomal membrane
by chloroaluminum phthalocyanine tetrasulfonate. Clin. Res. 36:376, 1988.
12. Khan IU, Athar M, Mendel D, Krutmann J, Mukhtar H, Guyre PM, Elmets CA.
Porphyrin photosensitization inhibits FcRI receptor expression on human
monocytes in a highly specific manner. Clin. Res. 36, 1988.
35
13. Athar M, Hasan SK, Srivastava RC. Evidence for the involvement of hydroxyl
radicals in nickel-mediated enhancement of lipid peroxidation: Implications for
nickel carcinogenesis. 4th Asian Pacific Congress of Clinical Biochemistry.
Hong Kong, 1988.
14. Mukhtar H, Athar M, Lloyd JR, Bickers DR. Malignant conversion of ultravioletB (UVB) and 7,12 dimethyl benz(a)anthracene (DMBA)-induced murine skin
papilloma by free radical generating compounds: Protective effect of all-trans
retinoic acid (RA). Proc. Am. Assoc. Cancer Res. 30:208, 1989.
15. Nontasut C, Athar M, Zaim MT, Mukhtar H, ElmetsCA. Evidence for the
involvement of superoxide anions in 8-methoxypsoralen mediated cutaneous
photosensitivity in vivo. J. Invest. Dermatol. 92:492, 1989.
16. Mukhtar H, Athar M, Lloyd JR, Bickers DR. All-trans retinoic acid exerts a novel
anticarcinogenic effect by inhibiting malignant conversion of skin papillomas. J.
Invest. Dermatol. 92:47, 1989.
17. Athar M, Bickers DR, Mukhtar H. Inhibition of benzoyl peroxide tumor
promotion in 7,2 dimethyl benz(a)anthracene treated skin of Sencar mice by the
antioxidants, nordihydroguaiaretic acid and diallyl sulphide. J. Invest. Dermatol.
92:398A, 1989; Clin. Res. 37:628A, 1989.
18. Bickers DR, Urban SA, Athar M, Mukhtar H. Photodynamic therapy of
cutaneous cancer with chloroaluminum phthalocyanine: Mechanistic studies.
Skin Pharmacol. 2:42, 1989.
19. Mukhtar H, Athar M, Lloyd JR. Bickers DR. Protection against progression of
benign papillomas to malignant carcinomas by all-trans-retinoic acid. Skin
Pharmacol. 2:43, 1989.
20. Raza H, Athar M, Bickers DR, Mukhtar H. Inhibition of benzoyl peroxideinduced epidermal ornithine decarboxylase and tumor promotion by
nordihydroguaiaretic acid in Sencar mice. Skin Pharmacol. 2:44, 1989.
21. Mukhtar H, Athar M, Agarwal R, Elmets CA,Bickers DR. Chloroaluminum
phthalocyanine tetrasulfonate (AlPCTS)-mediated photodynamic therapy of
cutaneous tumors. Photochem. Photobiol. 51(suppl.):74S, 1990.
22. Mukhtar H, Athar M, Raza H., Inhibition of benzoyl peroxide mediated skin
tumor promotion by antioxidants, diallyl sulfide and nordihydroguaiaretic acid.
Toxicologist. 10:934, 1990.
23. Athar M, Ali S, Siddiqui MY, Khan HA, Sultana S. Role of Reactive Oxygen
Species in Cutaneous Chemical Carcinogenesis. Intl. J. Toxicol. Occup.
Environ. Hlth. 1:86, 1991.
24. Abdulla M, Athar M. The Nutritional and Toxicological Effects of Trace
Elements. Intl. J. Toxicol. Occup. Environ. Hlth. 1:80, 1991.
36
25. Elmets CA, Athar M, Zaidi SI, Mukhtar H. Contact sensitivity to dimethyl
benz(a) anthracene is influenced by the genes within the major
histocompatibility complex and receptor locus. Clin. Res. 40:A309, 1992.
26. Abdulla M, Athar M. Public health aspects of trace elements in developing
countries. J. Trace Elements Exp. Med. 5:89, 1992.
27. Mirando WS, Athar M, Mukhtar H, Ellner JJ. Elmets CA. UV radiations and
photosensitizers plus light promote monocyte antimicrobial activities. Clin. Res.
40:A541, 1992.
28. Athar M, Sharma SD, Khanna T, Pandeya KB, Tripathi IP. Novel superoxide
dismutase mimics abrogate O2.- - mediated damage to biological system. Intl.
J. Toxicol. Occup. Environ. Hlth. 2:61, 1993.
29. Ali B, Khanna P, Srivastava SC, Athar M, Sultana S. Modification of hydrolytic
metabolism of xenobiotics following fluoride exposure. Intl. J. Toxicol. Occup.
Environ. Hlth. 2:27, 1993.
30. Kishore K, Athar M, Seth SD, Singh U, Siddiqui HH, Khan HA. Trace elements
in arthritides. Intl. J. Toxicol. Occup. Environ. Hlth. 2:45, 1993.
31. Behl PN, Arora RB, Agarwal A, Abdulla M, Athar M, Khan HA. Trace Metal
alterations in inflammatory Acne Vulgaris. Intl. J. Toxicol. Occup. Environ.
Hlth. 2:53, 1993.
32. Dashti H, Behbehani A, Favier A, Abdulla M, Athar M. The role of reactive
oxygen species in health and disease. Intl. J. Toxicol. Occup. Environ. Hlth.
2:119, 1993.
33. Kishore K, Singh U, Athar M, Seth SD, Khan HA. Status of trace elements in
Indian patients of Osteoarthritis. Intl. J. Toxicol. Occup. Environ. Hlth. 2:131,
1993.
34. Ali S, Siddiqui A, Bader GN, Srivastava SP, Athar M, Ali B. Age related
responses of drug metabolizing enzymes to MANCOZEB, a Zn++-Mn++containing fungicide. Intl. J. Toxicol. Occup. Environ. Hlth. 2:40, 1993.
35. Islam F, Sohaila SE,.Abbas, Vohora SB, Athar M, Watanabe Y, Hayaishi O.
Effect of selenium on behavioural, biogenic amines and phospholipase A 2. J.
Neurochem. 65:S21, 1995.
36. Misra GV, Vohora SB, Athar M. Mercury and lead preparations used in Unanitibb (Greco-Arab) medicine. Are these toxic? J. Trace Elements Exp. Med.
9:138-139, 1996.
37. Ali S, Abdulla M, Jain SK, Athar M. Paraquat damages PBR322 plasmid DNA:
role of reactive oxygen species. J. Trace Elements Exp. Med. 9:64-65, 1996.
38. Islam F, Sohaila SE, Sayeed I, Imam SZ, Athar M. Selenium inhibits sleep:
Involvement of lipids and neurotransmitters. J. Neurochem. 69:S217, 1997.
37
39. Athar M.
Porphyrin-photosensitization, oxidative stress and skin tumor
promotion. J. Invest. Dermatol. 110:526, 1998.
40. Ansar S, Iqbal M, Athar M. Nordihydroguairetic acid (NDGA) is a potent
inhibitor of ferric nitrilotriacetate (Fe-NTA) mediated carcinogenesis in mice. J.
Trace Elements Exp. Med. 11:330, 1998.
41. Athar M. Oxygen-centered free radical reactions as tumor promoter and
progressor of benign tumors in mouse skin. J. Trace Elements Exp. Med. 11:
334-335, 1998.
42. Zhang YJ, Zhao, Santella RM, Athar M, Wang ZY, Bickers DR. Tea extracts
induce apoptosis by down regulating ras-p21 and enhancing the expression of
p53 in human breast carcinoma cells. Proc. Am. Assoc. Cancer Res. 40:532,
1999.
43. JZhao JF, Zhang YJ, Jin X-H, Athar M, Chen JY, Wang ZY, Bickers DR.
Tubeimo is a potent inhibition of tumor promotion in mouse skin. Proc. Am.
Assoc. Cancer Res. 40:260, 1999.
44. Kim AL, Athar M, Bickers DR, Gautier J. Ultraviolet B (UVB)-induced G1
arrest is mediated by down regulation of cyclin-dependent kinase 4 (CDK4) in
skin carcinoma cells lacking p53. Proc. Am. Assoc. Cancer Res. 41:248,
2000.
45. Athar M, Kim AL, Kalka K, Ahmad N, Mukhtar H, Gautier J, Bickers DR.
Ultraviolet B induces cell cycle arrest in G2/M phase in p53-mutant
immortalized skin keratinocytes. Proc. Am. Assoc. Cancer Res. 41:248249, 2000.
46. Kim AL, Athar M, Bickers DR,. Gautier J. Cell cycle regulation during
ultraviolet B (UVB)-induced murine skin tumor development. Proc. Am.
Cancer Res. 42:807, 2001.
47. Athar M, An KP, Connolly B, Morel KD, Kim AL, Aszterbaum M. Epstein Jr. EH,
Bickers DR. Immunohistochemical study of ultraviolet B (UVB)-induced COX-2
expression in murine skin. Proc. Am. Assoc. Cancer Res. 42:805, 2001.
48. An KP, Athar M, Katiyar SK, Connolly B, Aszterbaum M, Longley J, Kim AL,
Epstein, Jr. EH, Mukhtar H, Bickers DR. Enhanced cyclooxygenase-2
expression in UVB-induced murine and human skin tumors. J. Invest.
Dermatol. 116:506, 2001.
49. Kim AL, Athar M, Gautier J. Bickers DR. Cell cycle alterations during
ultraviolet B-induced murine skin tumorigenesis. J. Invest. Dermatol. 116:488,
2001.
50. Athar M, Morel KD, An KP, Kim AL, Kepelovich L, Bickers DR.
Chemopreventive effect of the cyclooxygenase inhibitor sulindac against UVBinduced expression of surrogate markers of skin cancer. J. Invest. Dermatol.
116:488, 2001.
38
51. Razazadeh H, Athar M. Evidence that iron-overload augments croton oil
promoted skin tumorigenesis in mice. Toxicol. 164:91-92, 2001.
52. Athar M, Russo J, Aszterbaum M, Kim AL, Zhang H, Tang X, Kopelovich L,
Epstein Jr. EH, Bickers DR. Augmented basal cell carcinomas development
in ptch+/- heterozygous knockout mice over-expressing ornithine
decarboxylase. Proc. Am. Assoc. Cancer Res. 43:1012, 2002.
53. Athar M, Russo JE, Kim AL, Zhang H, Tang X, Aszterbaum M, Kopelovich L,
Epstein Jr. .EH, Bickers DR. Innovative model for accelerated induction of
cutaneous basal cell carcinomas: ptch+/- heterozygous knockout mice overexpressing ornithine decarboxylase, J. Invest. Dermatol. 119:216, 2002.
54. Tang X, Athar M, Aszterbaum M, Kopelovich L, Epstein Jr. EH, Bickers DR.
Comparative Effects of COX-1 and COX-2 Inhibitors on UVB
Photocarcinogenesis in SKH-1 Mice. Proc. Am. Assoc. Cancer Res. 43:670,
2002.
55. Zhang H, Athar M, Tang X, Aszterbaum M, Kopelovich L, Epstein Jr. EH,
Bickers DR. Transcriptional activation of nuclear factor kappa B (NFkB) in
ultraviolet B (UVB)-induced basal cell carcinomas (BCCs) in ptch+/- mice.
Proc. Am. Assoc. Cancer Res. 43:867, 2002.
56. Kim AL, Athar M, Tang X, Aszterbaum M, Kopelovich L, Epstein Jr., EH,
Bickers DR. Blockade of hedgehog signaling inhibits ultraviolet B (UVB)induced basal cell carcinomas (BCCs) in ptch+/- knockout heterozygous
mice. Proc. Am. Assoc. Cancer Res. 43:1008, 2002.
57. Russo JE, Athar M, Tang X, Aszterbaum M, Kopelovich L, Epstein Jr. EH,
Bickers DR. -difluoromethyl ornithine (DFMO), an irreversible inhibitor of
ornithine decarboxylase, abrogates ultraviolet B (UVB)-induced skin
carcinogenesis in SKH-1 hairless mice. Proc. Am. Assoc. Cancer Res. 43:
1145-1146, 2002.
58. Aszterbaum M, Heber Jt, Lee K, Athar M, Kopelovich L, Bickers DR, Epstein,
Jr. EH. Chemoprevetion of basal cell carcinomas in the ptc+/- mouse. 2002.
Proc. Am. Assoc. Cancer Res. 43:514, 2002.
59. Tang X, Athar M, Kim AL, Kopelovich L, Epstein Jr., EH, Bickers DR. Novel
approach to cancer chemoprevention: Inhibition of sonic hedgehog (shh)
signaling by cyclopamine (CPN) abrogates ultraviolet B(UVB)-induced basal
cell carcinomas (BCCs) in ptc1+/- heterozygous mice. J. Invest. Dermatol.
119:221, 2002.
60. Merk HF, Jugert FK, Jens B, Bickers DR, Athar M, Schiffer R, Wiegand U.
Target tissue regulation of retinoic acid isomers and their 4-oxo derivatives in
cultured normal human keratinocytes. J. Invest. Dermatol. 119:346, 2002.
61. Blaner WS, Vogel S, Athar M, Merk HF, Jugert FK, Baron J, Wiegand U,
Bickers DR. Use of proteomics to probe retinoid action in cultured normal
human keratinocytes. J. Invest. Dermatol. 119:348, 2002.
39
62. Bickers DR, Tang X,
L, Epstein Jr. EH,
expressing ornithine
Carcinomas (BCCs)
2002.
Russo J, Zhang H, Aszterbaum M, Kim AL, Kopelovich
Athar M. Ptch+/- Hetrozyous Knockout Mice Overdecarboxylase: Possible Model for Multiple Basal Cell
in Gorlin’ Syndrome. J. Invest. Dermatol. 119:749,
63. Athar M, Tang X, Kim AL, Aszterbaum M, Kopelovich L, Epstein Jr. EH,
Bickers DR. Novel Targets for Cancer Chemoprevention: Blockade of
Hedgehog signaling Inhibits Basal Cell Carcinomas (BCCs) in Ptch+/Hetrozyous Knockout Mice. J. Invest. Dermatol. 119:749, 2002.
64. Athar M, Tang X, Kim AL, Kopelovich L, Epstein Jr. EH, Bickers DR.
Cyclopamine as a specific inhibitor of hedgehog signaling and a novel
inhibitor of basal cell carcinomas (BCCs) in ptch +/- knockout heterozygous
mice. Cancer Epidem. Biomar. 11:B213 Part 2, 2002.
65. Hebert J, Athar M, Aszterbaum M, Kopelovich L, Bickers DR, Epstein Jr EH.
Tazarotene chemoprevention of UV-induced basal cell carcinomas in the
ptc1+/- mouse. Cancer Epidem. Biomar. 11:B217 Part 2, 2002.
66. Tang X, Russo J, Epstein Jr. EH, Kopelovich L, Bickers DR, Athar M. Alphadifluoromethylornithine (DFMO), a suicidal inhibitor of ornithine decarboxylase
(ODC) prevents basal cell carcinomas (BCCs) in ptc+/- heterozygous
knockout mice. J. Invest. Dermatol. 121:200, 2003.
67. Athar M, Tang X, Kopelovich L, Bickers DR. p53 stabilization by CP-31398
restores wild type p53-dependent function in ultraviolet B (UVB)-irradiated
murine skin and in A431 cells. J. Invest. Dermatol. 121:208, 2003.
68. Lee JL, Bickers DR, Athar M. Role of prostaglandin E2 receptors in the
pathogenesis of ultraviolet B (UVB)-induced non-melanomas skin cancer. J.
Invest. Dermatol. 121:209, 2003.
69. Kim AL, Zhu Y, Kopelovich L, Bickers DR, Athar M. DNA damage and cell
cycle alterations in Ultraviolet B (UVB)-induced murine and human basal cell
carcinomas (BCCs). J. Invest. Dermatol. 121:211, 2003.
70. Kim AL, Zhu Y, Bickers DR, Athar M. P38 mitogen-activated protein kinases
(MAPKs) mediate ultraviolet B (UVB)-induced COX-2 expression and
inflammation in the skin of SKH-1 hairless mice. J. Invest. Dermatol. 121:
769, 2003.
71. Kim AL, Zhu Y, Tang X, Kopelovich L, Epstein, Jr. EH, Bickers DR, Athar M.
Cell cycle alterations in the development of Ultraviolet B (UVB)-induced
Murine and Human Basal Cell Carcinomas (BCCs).
Proc. Am. Assoc.
Cancer Res. 44:21, 2003.
72. Tang X, Kopelovich L, Epstein Jr. EH, Bickers DR, Athar M. A suicidal
inhibitor of ornithine decarboxylase (ODC) prevents basal cell carcinomas
(BCCs) in ptc+/- heterozygous knockout mice. Proc. Am. Assoc. Cancer
Res. 44:1130, 2003.
40
73. Tang X, Kim AL, Kopelovich L, Bickers DR, Athar M: Chemical inhibition of
nuclear factor kappa B (NFκB) prevents UVB-induced squamous cell
carcinomas (SCCs) in SKH-1 mice. J. Invest. Dermatol. 122:A25, 2004.
74. Hebert J, Khaimskiy Y, Athar M, Kopelovich l, Bickers D. Epstein EH.
Phorbol-12 myristate 13-acetate (TPA) inhibits the induction of basal cell
carcinomas in ptch1+/-Mice. J. Invest. Dermatol. 122:A28, 2004.
75. Kim AL, Zhu H, Zhu Y, Athar M, Bickers DR. Resveratrol-induced modulation of
MEK-ERK signaling and cell cycle regulation in human epidermoid carcinoma
A431 cells. J. Invest. Dermatol. 122:A101, 2004.
76. Zhu Y, Kim AL, Tang X, Stiller M, Coppola C, Barsanti F, Athar M, Bickers DR.
p38 MAP kinase signaling mediates inflammatory responses in UVB-irradiated
human skin. J. Invest. Dermatol. 122:A103, 2004.
77. Bhasin G, Kausar H, Athar M, Iron-induced oxidative stress augments UVBmediated tumor promotion. J. Nutrition. 134:3546S-3547S, 2004.
78. Paul B, Athar M, Kim AL, Bickers DR, Gilmour SK. The green tea polyphenol
epigallocatechin—3-gallate inhibits skin tumor formation in ODC/Ras transgenic
mice. Proc. Am. Assoc. Cancer Res. 45:931, 2004.
79. Xie J, Athar M, Chengxin L, Tang X, Chi S, Bickers DR, Hebert J, Epstein Jr.
EH. Inhibition of SMO signaling prevents ultraviolet B-induced basal cell
carcinomas through induction of Fas expression and apoptosis. . Proc. Am.
Assoc. Cancer Res. 45:681, 2004.
80. Tang X, Kim AL, Zhu H, Kopelovich L, Bickers DR, Athar M. Budesonide and
a retinoid X receptor-selective ligand bexarotene prevents the development of
Ultraviolet B-induced skin cancer in SKH-1 hairless mice. Proc. Am. Assoc.
Cancer Res. 46:1017, 2005.
81. Kim AL, Zhu Y, Tang X, Han L, Kopelovich L, Athar M, Bickers DR. Topical
CP-31398, a mutant p53-rescuing drug, suppresses the development of
ultraviolet B-induced skin cancer in SKH-1 hairless mice. Proc. Am. Assoc.
Cancer Res. 46:628, 2005.
82. Tang X, Kim AL, Zhu Y, Kopelovich L, Bickers DR, Athar M. Budesonide
and a retinoid X Receptor-selective ligand bexarotene prevent the
development of Ultraviolet B-induced skin cancer in SKH-1 hairless mice. J.
Invest. Dermatol. 124:A25, 2005.
83. Kim AL, Zhu Y, Tang X, Han L, Kopelovich L, Athar M, Bickers DR. Rescue
of mutant p53 by CP-31398 suppresses the induction of squamous cell
carcinomas (SCCs) by ultraviolet B (UVB) irradiation in SKH-1 hairless mice, J.
Invest. Dermatol. 12: A25, 2005.
84. Zhu Y, Kopelovich L, Athar M, Kim AL, Bickers DR. Resvertrol-mediated
modulation of NFkB activity by SIRT1 in human epidermoid carcinomas
(A431) cells. J. Invest. Dermatol. 124:A98, 2005.
41
85. Tang X, Kim AL, Zhu Y, Kopelovich L, Bickers DR, Athar M. CP-31398, a
mutant p53-rescuing chemical agent, suppresses Ultraviolet B (UVB)-induced
skin photocarcinogenesis in SKH-1 hairless mice (SKH). J. Invest. Dermatol.
125:A59, 2005.
86. Kim AL, Tang X, Russo J, Kopelovich L, Athar M, Bickers DR. A Novel
Mouse Model for Spontaneous and Ultraviolet B (UVB)-Induced Basal Cell
Carcinomas (BCCs): Ptch1 Heterozygosity Bred into a Tumor-Susceptible
SKH-1 Hairless Genetic Background. J. Invest. Dermatol. 125:A61, 2005.
87. Tang X, Kim AL, Zhu Y, Han L, Kopelovich L, Bickers DR, Athar M. p53
modulation by CP-31398 enhances its mitochondrial translocation leading to
induction of apoptosis and blockade of the growth of UVB-induced squamous
cell carcinoma. J. Invest. Dermatol. 126:S83, 2006.
88. Bickers DR, Herman S, Kim AL, Athar M. TGFβ1 Pathway Proteins in Human
Non-Melanoma skin Cancers (NMSC): Implications for EpithelialMesenchymal Transition and Metastatic Potential. J. Invest. Dermatol. 126:
S84, 2006.
89. Kim AL, Zhu Y, Athar M, Bickers DR. Induction of cellular senescence offers
a novel approach for growth arrest, chemoprevention and treatment of
squamous cell carcinoma of the skin. J. Invest. Dermatol. 126:S84, 2006.
90. Zhang L, Tang X, Kim AL, Kopelovich L, Bickers DR, Athar M. Ptc1+/-/SKH-1
hairless mice spontaneously develop rhabdomyosarcomas with highpenetrance. J. Invest. Dermatol. 127:S22, 2007.
91. Bickers DR, Tang X, Kim AL, Kopelovich L, Athar M. Nuclear factor Kappa B
(NFkB) blockade inhibits its activation by ultraviolet B (UVB) and UVBinduced photocarcinogenesis in murine skin. J. Invest. Dermatol. 127:S26,
2007.
92. Wu A, X. Tang, Y. Zhu, A. L. Kim1, L. Kopelovich, D. R. Bickers and M. Athar,
Cyclooxygenase-2 (COX-2) inhibition by nimesulide blocks ultraviolet-B
(UVB)-induced photocarcinogenesis in mouse skin. J. Invest. Dermatol., 127,
s25, (2007).
93. Tang X, Kim AL, Kopelovich L, Bickers DR, Athar M. Use of genetically
engineered murine models to assess the chemoprevention of nonmelanoma
skin cancer (NMSC) by alpha-difluoromethylornithine (DFMO). J. Invest.
Dermatol. 127:S22, 2007.
94. Athar M, Tang X, Kim AL, Kopelovich L, Bickers DR. Interaction of p53 and
sonic hedgehog signaling pathways in the development of ultraviolet-B
(UVB)-induced basal cell carcinomas (BCCs) in murine skin. J. Invest.
Dermatol. 127:S96, 2007.
42
95. Kim KH, Zhu Y, Back JH, Tang X, Kopelovich L, Athar M, Kim AL, Bickers
DR. Resveratrol suppresses ultraviolet B (UVB)-induced SCC formation in
p53+/-/SKH-1 hairless mice through modulation of mediators of epithelial to
mesenchymal transition (EMT). J. Invest. Dermatol. 127:S29, 2007.
96. Kim H, Casta A, Cirman T, Tang T, Bickers DR, Athar M, Christiano AM.
Hairless mutation in SKH1 mice confers susceptibility to ultraviolet-B (UVB)induced tumorigenesis via disruution of NFkB signaling. J. Invest. Dermatol.
127:S30, 2007.
97. Tang X, Kim AL, Kopelovich L, Bickers DR, Athar M. Genetic Background
And p53 Gene-dose Are Major Susceptibility Factors For Basal Cell
Carcinomas (BCCs) in Murine Skin. J. Invest. Dermatol. 127:S96, 2007.
98. Kim AL, Back JH, Zhu Y, Athar M, Tang X, Kopelovich L, Bickers DR.
Senescence driven by reactive oxygen species (ROS) via NF-kappa B
suppresses UVB-induced skin photocarcinogenesis. J. Invest. Dermatol. 127:
S90, 2007.
99. Athar M, Tang X, Kim AL, Bickers DR, Kopelovich L. P53 inactivation
augments sonic hedgehog signaling-dependent murine skin carcinogenesis.
Proc. Am. Assoc. Cancer Res. 48:4560, 2007.
100. Holzer AM, Nasti TH, Yusuf N, Katiyar SK, Athar M, Elmets CA. IL-12/23
suppresses the growth of melanocytic nevi in mice. J. Invest. Dermatol.,
129:S33, 2009.
101. Elmets CA, Yusuf N, Nasti TH, Holzer AM, Xu H, Athar M, Timares L.
Mutant ras proteins are capable of eliciting allergic contact hypersensitivity
responses. J. Invest. Dermatol. 129:S34, 2009.
102. Yusuf N, Nasti TH, Holzer AM, Huang C, Timares L, Xu H, Athar M,
Elmets CA. Heat shock proteins-27 and -70 have a functional role in
cutaneous cell-mediated immune responses through effects on dendritic cells.
J. Invest. Dermatol. 129:S34, 2009.
103. Back JH, Zhu Y, Athar M, Bickers DR, Kim AL. Resveratrol regulates
mTOR-dependent RhoA activity during induction of premature cellular
senescence (PCS). J. Invest. Dermatol. 129: S35, 2009.
104. Wang CC, Barnes S, Beatrous S, Herring R, Wilson L, Elmets CA, Athar
M. Differential proteomic analysis of the effects of immunosuppressant,
Cyclosporine A and rapamycin, on squamous cell carcinoma by 2D difference
gel electrophoresis and mass spectrometry. J. Invest. Dermatol. 129:S35,
2009.
105. Bickers DR, Tang X, Zhu Y, Daly ME, Liu WJ, Kopelovich L, Kim AL, Athar
M. p53-modulating compounds inhibit ultraviolet B (UVB)-induced skin
cancer development in genetically engineered murine models. J. Invest.
Dermatol. 129:S97, 2009.
43
106. Tang X, Zhu Y, Back JH, Kopelovich L, Athar M, Kim AL, Bickers DR.
Resveratrol suppresses ultraviolet B (UVB)-induced basal cell carcinoma
(BCC) growth via cyclin D1 modulation in Ptc1+/-/SKH-1 mice. J. Invest.
Dermatol. 129:S110, 2009.
107. Beatrous SE, Xu J, Xu H, Kurundkar AR, Maheshwari A, Kopelovich L,
Elmets CA, Athar M. Cyclosporine A (CsA), an immunosuppressant,
transforms squamous cell carcinoma (SCC) to a more invasive phenotype: a
non-immunological effect. J. Invest. Dermatol. 129:S110, 2009.
108. Kim H, Tsuruta Y, Martin CM, Wu J, Andea AA, Grizzle WE, Fineberg NS,
Katiyar SK, Elmets CA, Athar M, Timares L. A novel role for Bid in promoting
UV-induced cell cycle checkpoint function and suppression of skin
carcinogenesis. J. Invest. Dermatol. 129:S138, 2009.
109. Moeinpour F, Athar M, Figueiredo L et al. P53 mediates tissue damage
after trauma-hemorrhage via mitochondrial-dependent apoptotic signaling.
Shock. 31:88-89, 2009.
110. Xu J, Heilpern C, Xu H, Kopelovich L, Athar M,. CP-31398 inhibits growth
of human rhabdomyosarcoma cells by activating p53-mitochondria-dependent
apoptosis. . Proc. Am. Assoc. Cancer Res. 50:, 2009.
111. Singh T, Kapur P, Chaudhary SC, Elmets CA, Kopelovich L, Athar M.
Nitric oxide donor sulindac inhibits photocarcinogenesis by modulating
epithelial mesenchymal transition and mitogen activated protein kinase
signaling in SKH-1 hairless mouse skin. Proc. Am. Assoc. Cancer Res.
51:, 2010.
112. Singh T, Kapur P, Chaudhary SC,1 Elmets CA, Kopelovich L, Athar M.
RB-041, an estrogen receptor beta agonist inhibits skin photocarcinogesis in
SKH-1 hairless mice. J. Invest. Dermatol. 130:S23, 2010.
113. Zhu Y, Back JH, Tang X, Athar M, Kim AL, Bickers DR. Akt inhibition
suppresses the growth of basal cell carcinomas (BCCs) in Ptc1+/-/SKH-1
mice by blocking Akt and sonic hedgehog (Shh)-dependent pathways. J.
Invest. Dermatol. 130:S27, 2010.
114. Tang X, Zhu Y, Back JH, Athar M, Kim AL, Bickers DR., p38 MAPK
regulates oxidative stress in UVB-induced squamous cell carcinoma by
blocking NADPH NOX2. J. Invest. Dermatol. 130:S27, 2010.
115. Back JH, Zhu Y, Athar M, Bickers DR, Kim AL. mTOR-dependent Sirtuin 1
phosphorylation regulates DNA damage-induced cancer cell survival in UVBinduced skin carcinogenesis. J. Invest. Dermatol. 130:S28, 2010.
116. Xu J, Weng Z, Kim H, Li C, Kopelovich L, Christiano AM, Bickers DR,
Athar M. Hairless gene confers resistance to nonmelanoma skin cancer
development. J. Invest. Dermatol. 130:S30, 2010.
44
117. Turnham J, Cantrell W, Andea AA, Shafi R, Athar M Elmets CA. Loss of
membrane E-cadherin and expression of p53 are molecular markers of
progression of sun-damaged skin to actinic keratoses. J. Invest. Dermatol.
130:S47, 2010.
118. Shafi R, Cantrell W, Grizzle WE, Athar M, Elmets CA. T4 endonuclease V
liposome (T4N5) treatment ameliorates inflammation-related biomarkers and
enhances apoptosis in both sun-exposed skin and AKs in chronically immune
suppressed renal transplant patients (RTPs). J. Invest. Dermatol. 130:S58,
2010.
119. Chaudhary SC, Singh T, Kapur P, Durundkar D, Weng Z, Elmets CA,
Kopelovich L, Athar M. Nitric oxide (NO)-releasing exisulind suppresses
UVB-induced cutaneous photocarcinogenesis. J. Invest. Dermatol.
130:S137, 2010.
120. Back J, Zhu Y, Tang X, Athar M, Kim AL, Bickers DR. Shh and Akt1
signaling pathways converge through mammalian target of rapamychin
(mTOR) signaling to drive the growth of BCCs. J. Invest. Dermatol. 131:
S23, 2011.
121. He D, Li H, Yusuf N, Elmets CA, Athar M, Katiyar S, Li J, Mountz J, Xu H.
IL-17 receptor A deficient mice are resistant to chemical carcinogen induced
cutaneous tumors. J. Invest. Dermatol 131: S24, 2011.
122. Rudemiller K, Nasti T, Twitty G, Kim H, Rivera A, Roth J, Holzer A, Tsuruta
Y, Yusuf N, Athar M, Elmets C, Timares L. Engineered dendritic cell (DC)- or
DNA-based vaccines raise immune responses to a carcinogen-induced point
mutation of H-ras oncogene that protects against tumor development. J.
Invest. Dermatol. 131: S25, 2011.
123. Byekova YA, Herrmann JL, Xu J, Elmets CA, Athar M. Liver kinase B1 in
the pathogenesis of UVB-induced murine basal cell carcinoma. J. Invest.
Dermatol. 131:S26, 2011.
124. Arumugam A, Weng Z, Kopelovich L, Athar M. Combined inhibition of
sonic hedgehog (shh) and nuclear factor kB (NF kB) signaling pathways in
the prevention of basal cell carcinomas (BCCs). J. Invest. Dermatol. 131:
S28, 2011.
125. Shafi R, Cantrell W, Grizzle WE, Athar M, Elmets CA. T4 endonuclease V
liposome (T4N5) treatment ameliorates gene expression profile in actinic
keratoses and sun-exposed skin of renal transplant patients. J. Invest.
Dermatol. 131: S90, 2011.
126. Chaudhary SC, Krundkar D, Singh T, Weng Z, Elmets CA, Kopelovich L,
Athar M. Rapamycin augments the chemopreventive effects of sulindac and
suppresses UVB-induced cutaneous photocarcinogenesis in PTCH+/- hairless
mice. J. Invest. Dermatol. 131: S26, 2011.
45
127. Xu J, Kopelovich L, Athar M. Hair follicle disruption leads to enhanced
UVB-induced cutaneous inflammation and basal cell carcinoma development.
Proc. Am. Assoc. Cancer Res. 52: 2011.
128. Li C, Xu J, Weng Z, Wen J, Athar M. Arsenic induces unfolded protein
response signaling, inflammation and tumorigenesis in murine skin. Proc. Am.
Assoc. Cancer Res. 52: 2011
129. Weng Z, Arumugam Z, Athar M. C-terminal patched polymorphism alters
UVB-induced susceptibility to skin cancer in p53+/-/C57BL/6 and Ptch+/-SKH-1
mice. Proc. Am. Assoc. Cancer Res. 52: 2011.
130. Gurpinar E, Sun Y, Keeton A, Tinsley H, Gary B, Butler BL, Binkowski BF,
Kopelovich L, Athar M, Piazza GA. NO-NSAIDS inhibit colon tumor cell growth
by a cGMP-independent mechanism. Proc. Am. Assoc. Cancer Res. 52:
2011.
BOOKS
1. M. Athar, SB Vohora. Heavy Metals and Environment. Wiley Eastern Limited,
New Delhi, INDIA, 1995.
2. M Abdulla, SB. Vohora. M Athar (Eds.). Trace and Toxic Elements in
Nutrition and Health. Wiley Eastern Limited, New Delhi, INDIA, 1995.
3. HM. Said, MA. Rahman, M Abdulla, SB Vohora, M Athar. (Eds.). Elements in
Liver. Hamdard Foundation Publication, 1996.
4. SB. Vohora, M Athar. Mineral Drugs. Narosa Publishing House, New Delhi,
INDIA, 2008.
46
LECTURESHIPS
Plenary Lecture on "Activation of xanthine oxidase pathway leading to
generation of superoxide anion as a mechanism for porphyrin-mediated
cutaneous photosensitization" in the annual meeting of the Society of
Investigative Dermatology, Chicago, USA (1988).
Invited talk on "Role of Oxygen Radicals in Chemical Carcinogenesis",
Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI
53226, USA (July 1988).
Delivered a Lecture Series to undergraduate students of Mumtaz Degree
College (Lucknow University, Lucknow) on Pollution, Genes and Cancer
(March, 1989).
Plenary Lecture on "Free radicals, hydrocarbons and Cancer" In the
Analytical Techniques For Fossil Fuels and Lubricants, New Delhi
(December, 22-24, 1992).
Invited talk on "Photodynamic therapy as a new modality for the cancer
treatment" given at the Skin Institute and School of Dermatology, New Delhi
(February, 1992).
Invited to give a talk on "Reactive oxygen species and chemical
carcinogenesis" at the Department of Chemistry, A.P.S University, Rewa,
M.P.
Invited talk on "Calcium, inositol phosphate messenger signals and
oxidative stress" at the International Conference on Alcohol, Micronutrients
and Cell function (Trivendrum, February 12, 1992).
Plenary Lecture on "Novel Superoxide Dismutase Mimics Abrogate O2.- Mediated Damage to Biological System" in the 4th International Conference
on Health and Disease: Effects of Essential and Toxic Trace Elements, New
Delhi, INDIA (February 8-12, 1993).
Invited talk on "Role of Oxidative Stress in Toxicology" at the symposium on
India's Environment Today and Tomorrow, Bose Institute, Calcutta, INDIA
(August 27-28, 1993).
Invited talk on "Abrogation of O2.--Mediated Damage to Biological System
by Copper Superoxide Dismutase Mimics" at the International Symposium
on Trace Elements in Physiology, Antalya, TURKEY (November 9-11, 1993).
Invited talk on "Reactive oxygen species and cancer development"
delivered at Department of Microbiology, Faculty of Medicine, University of
Kuwait, Kuwait (March 28, 1995).
Invited talk on "Free radicals and skin tumor development" delivered at Skin
Diseases Research Centre, Department of Dermatology, Case Western
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Reserve University, University Hospitals of Cleveland, Cleveland, Ohio, USA
(June 29, 1995).
Invited talk on "Free Radicals and Tumorigenesis", R & D Centre, Indian Oil
Corporation, Haryana, India (July, 1995).
Invited talk on "Role of free radicals in carcinogenesis" delivered at
Department of Biochemistry, Faculty of Science, University of Kuwait,
Kuwait, (November 26, 1996).
Invited talk on "Oxidants, anti-oxidats and tumor development" delivered at
an interdisciplinary symposium on DIVERSITY IN MODREN BIOLOGY, New
Delhi, India (September 21-22, 1997).
Invited talk on "Role of free radicals in tumor development" delivered at the
INTERNATIONAL SYMPOSIUM ON FREE RADICALS IN MEDICINE AND
BIOLOGY, Udaipur, India (September 22-24, 1997).
Invited talk on "Anticarcinogenesis strategies using dietary agents"
delivered at the Symposium on Environment and Health, Meerut, India
(October 19-21, 1997).
Invited talk on "Free radicals and cancer" delivered at the Department of
Chemistry, Faculty of Science, Dayalbagh Educational Institute, Dayalbagh,
Agra, India (November 16, 1997).
Invited talk on "Mechanisms of Cellular death mediated by photosensitizers"
delivered at a Symposium on ‘Applications of photodynamic technology in
health care’, Delhi, India (Dec 1-3, 1997).
Invited talk on `Free radicals, free radical scavengers and process of
carcinogenesis, Department of Chemistry, Bareilly College, Bareilly, India
(24 January, 1998).
Invited talk on "Photodynamic therapy and skin photosensitization: Role of
free radicals" delivered at the Institute of Nuclear Medicine and Allied
Sciences, Defence Research and Development Organization, Delhi, India
(March, 1998).
Invited talk on ‘Oxidative stress and tumor promotion’, Department of
Chemistry, Dalhousie University, Halifax, Canada (4 August, 1999).
Invited talk on ‘p35, a baculovirus gene product acts as an antioxidant to
inhibit apoptosis’, Department of Dermatology, University of Dusseldorf,
Dusseldorf, Germany (8 October, 1999).
Key-note talk on ‘Prevention of cancer risk due to exposure to chemical
agents from petrolium based industries’, Petrochem-2001 4th international
Conference and exhibition, New Delhi, India (January 9-12, 2001).
48
Plenary Lecture on "Novel targets for cancer chemoprevention: Blockade of
hedgehog signaling inhibits BCCs development in ptch+/- knockout
heterozygous mice” at the annual Conference of the European Society of
Dermatologic Research, Geneva, Switzerland (September 18-21, 2002).
Invited talk on ‘Basal cell carcinoma: Animal models and prevention’,
Department of Dermatology, University of Birmingham, Alabama, USA
(October 23, 2002).
Plenary Lecture on "p53 stabilization CP-31398 restores wild-type p53dependent function in ultraviolet B (UVB)-irradiated murine skin and in A431
cells” at the annual Conference of the Society of Investigative Dermatology,
Miami, Florida (April 30- May 4, 2003).
Invited talk on ‘Cancer Chemoprevention: Pre-clinical Models and
Approaches for Skin Cancer’, PGRD-Groton Laboratories, Cancer Drug
Discovery, Groton, CT, USA (June 29, 2003).
Invited talk on "Drug and Carcinogen Metabolism: Recent Advances"
delivered at the Department of Toxicology, Meerut University, India (October,
2004).
Invited talk on "Molecular Targets of Chemoprevention of Cancer: Lessons
from Mouse Models" delivered at the Department of Biotechnology, AMU,
Aligarh, India (February, 2005).
Invited talk on "Developing Genetically Engineered Mouse Models for
Cancer Chemoprevention" delivered at the Tata Memorial Cancer Centre,
Department of Atomic Energy, Bombay, India (April, 2005).
Invited talk on “p53 and Sonic Hedgehog Pathways in the Chemoprevention
of Non-melanoma Skin Cancer”, Susan Lehman Cullman Laboratory for
Cancer Research, Department of Chemical Biology Ernest Mario School of
Pharmacy, Rutgers, The State University of New Jersey, 164
Frelinghuysen Road Piscataway, NJ 08854, USA (October 14, 2005).
Invited talk on “Activating Mutant p53 as an Approach for the Prevention of
Non-melanoma Skin Cancer”, Department of Dermatology, University of
Birmingham, Alabama, USA (October 25, 2005).
Plenary Lecture on "Interaction of p53 and sonic hedgehog signaling
pathways in the development of ultraviolet-B (UVB)-induced basal cell
carcinomas (BCCs) in murine skin” at the annual Conference of the Society
of Investigative Dermatology, Los Angeles, California (May 9-12, 2007).
Invited SDRC Lecture on “Genetic determinants of susceptibility to the
pathogenesis of basal cell carcinoma” at the University of Alabama at
Birmingham, USA, November 14, 2007.
49
Invited Lecture on “Mutant p53 as a target for skin cancer
chemoprevention”, at the University of Alabama at Birmingham,
Comprehensive Cancer Center, USA, March 14, 2008.
Invited Lecture on “Mutant p53 as a target for non-melanoma skin cancer
chemoprevention” at Dermatology Grand Rounds, the University of
Wisconsin, USA, November 3, 2009.
Invited Lecture on “Inactivation of tumor suppressors, patched and p53 in
the pathogenesis of basal cell carcinoma, rhabdomyosarcoma, and
medulloblastoma” at University of Wisconsin Carbone Cancer Center,
November 4, 2009.
Invited Lecture on Single nucleotide polymorphism in patched and
susceptibility to basal cell carcinoma development.
Experimental
Therapeutics Seminar Series, the University of Alabama at Birmingham,
USA, May 20, 2010.
50