MODULE 6
1. Fajans titration uses _______ indicator.
A. Acid-base
B. Adsorption
C. Metal- ion
D. NOTA
2. Other name of ferric ammonium
sulphate
A.
B.
C.
D.
Ferric alum
Fe NH4 (SO4)2
Fe (NH4)2 (SO4)2
A and B
3. These are straight filaments arising from
the bacterial cell wall, making the
bacterium look like porcupine.
A.
B.
C.
D.
Capsule
Endospores
Fimbriae
Flagella
4. Standard solutions are also known as:
A.
B.
C.
D.
Test solutions
Volumetric solutions
Saturated solutions
NOTA
5. The end point in using ferric ammonium
sulphate is:
A.
B.
C.
D.
White precipitate
Red-brown color
Pink color
Blue color
6. A structural component of the cell that
may enhance virulence of the bacterium
include
A.
B.
C.
D.
Capsule
Hyalauronidase
Flagella
Lecitinase
7. Indicator in the Iodometric method of
analysis:
A.
B.
C.
D.
KMnO4
Methyl red TS
Methyl orange TS
Starch TS
8. Assay of diluted HCl is expressed in:
A.
B.
C.
D.
%w/w
%w/v
Both A and B
NOTA
9. The source of H antigen
A.
B.
C.
D.
Flagella
Cell wall
Pilus
Plasmid
10. Residue on Ignition is also called:
A.
B.
C.
D.
Loss on Ignition
Loss on Drying
Acid-insoluble ash
Sulfated ash
11. Limit of moisture in non-aqueous
titrimetric analysis is less than:
A.
B.
C.
D.
0.5 %
0.05%
0.2%
0.02%
12. A vaccine antigen that primarily
induces opsonizing antibody is
A.
B.
C.
D.
Hepatitis B virus vaccine
MMR vaccine
Rabies vaccine
H. influenzae type b vaccine
13. Method II of determining Iodine value
is also known as:
A.
B.
C.
D.
Hubl’s method
Wij’s method
Hanus method
AOTA
14. Standard Operating Procedure (SOP):
A. Concerned with record keeping
B. Done to facilitate recall
C. Step by step method on how to go
about a job
D. AOTA
17. The maximal reaction time for
tuberculin reaction
A.
B.
C.
D.
2-5 hours
6-10 hours
12-20 hours
48-72 hours
16. To determine the total ash, the sample
is incinerated at a temperature of 675 + 25°C. This temperature is represented by:
A.
B.
C.
D.
Very dull red heat
Dull red heat
White red heat
Bright red heat
Very dull red heat 500-550°C
Dull red heat
550-700°C
Bright red heat
800-1000°C
Yellow red heat
1000-1200°C
White red heat
1200-1600°C
17. A critical defect that would stop the
packaging line operation:
A.
B.
C.
D.
Wrong labels
Inverted labels
Misaligned labels
Smeared
18. Streptomycin is known for
A.
B.
C.
D.
Erythema nododum leprosum
Bone marrow depression
Discoloration of the teeth
Vestibular damage
19. Hydrolysis products of ASA:
A.
B.
C.
D.
Acetic acid + sodium hydroxide
Acetic acid + salicylic acid
Salicylic acid + sodium hydroxide
Sodium salicylate + water
C6H4OCOCH3COOH + H2O C6H4OHCOOH
+ CH3COOH
20. Pyrogen test in vitro:
A.
B.
C.
D.
Colorimeter
Fluorophotometer
Cylinder-plate method
LAL method
21. A spinal fluid specimen from a 28 year
old man shows N. meningitides. The DOC
is
A. Pen G
B. Amikacin
C. Kanamycin
D. Ethambutol
22. The type of glass most suitable for
parenteral preparation is:
A.
B.
C.
D.
Type I
Type II
Type III
NP
23. A firm’s removal or correction of a
distributed product which involves no
violation
A.
B.
C.
D.
Drug recall
Stock recovery
Market withdrawal
NOTA
24. Tetracycline may be the DOC for all
except:
A.
B.
C.
D.
LGV
Inclusion conjunctivitis
Hospital acquired PNX due to klebsiella
Psittacosis
25. A small volume intravenous solution
has a maximum volume of:
A.
B.
C.
D.
1000 ml
200 ml
500 ml
NOTA
26. A dye used in the leaker test:
A.
B.
C.
D.
Methylene blue
Phenolphthalein
Thymol blue
NOTA
27. Sulfamic acid (H3NSO3) is a primary standard
that can be used to standardize sodium
hydroxide. What is the molarity if 34.26mL
reacts with 0.3337g of sulfamic acid MW=97
A.
B.
C.
D.
0.304
0.1004
0.1005
0.403
28. The human papilloma virus is the
causative agent of:
A.
B.
C.
D.
Measles
Chancre
Warts
Herpes
29. Bleeding is a main stability problem
seen in:
A.
B.
C.
D.
Capsules
Ointments
Emulsions
Tablets
30. This expensive drug is given for
dapsone-resistancy M.leprae
A.
B.
C.
D.
Thalidomide
Para-aminosalicylic acid
Clofazime
Rifampicin
31. A spinal fluid specimen from a 28 year
old man shows N. meningitides. The DOC
is
A. Pen G
B. Amikacin
C. Kanamycin
D. Ethambutol
32. A sterilizing filter has a pore size of
A.
B.
C.
D.
0.5 µm
0.2 µm
1 µm
NOTA
33. This is an antifungal that acts as by
inhibiting lansosterol C14- demethylase,
an important enzyme in sterol synthesis
A.
B.
C.
D.
Griseofulvin
Miconazole
Flucytosine
Ampothericin
34. The human papilloma virus is the
causative agent of:
A.
B.
C.
D.
Measles
Chancre
Warts
Herpes
35. Clean room classifications are specified
in Federal Standard
A.
B.
C.
D.
211E
210E
209E
NOTA
36. Use to prevent one element from
interfering in the analysis of another
element
A.
B.
C.
D.
Masking agent
Demasking agent
Both a and b
NOTA
37. A type of relationship in which one
species of organism uses the body of a
larger species as its physical environment
and makes use of that environment to
acquire nutrients.
A. Commensalism
B. Mutualism
C. Parasitism
D. Symbiosis
38. The Philippines belongs to what
climactic zone:
A.
B.
C.
D.
I
II
III
IV
39. Describe how close a measure value is
to the true value
A.
B.
C.
D.
Accuracy
Precision
Range
Standard deviation
40. The minimum time period covered by
the data for accelerated stability studies
is:
A. 6 months
B. 12 months
C. 18 months
D. NOTA
41. Disintegration is an essential attribute
of this dosage form:
A.
B.
C.
D.
Plain coated tablet
Hard gelatin capsule
Chewable tablet
AOTA
42. Tetanus, botulism, diphtheria
A.
B.
C.
D.
E.
Immediate hypersensitivity
Cytotoxic antibody
Immune complex
Delayed hypersensitivity
NOTA
43. Which is not a biological indicator in
the validation of a moist heat sterilizer?
A.
B.
C.
D.
Bacillus stearothermophilus
Bacillus subtilis
Bacillus coagulans
NOTA
44. The acceptable pH level of water used
for pharmaceutical compounding is
A.
B.
C.
D.
Between 6.0 and 7.0
Between 5.0 and 7.0
Between 7.0 and 8.0
NOTA
45. Treatment of herpectic conjunctivitis
A.
B.
C.
D.
Streptomycin
Iododeoxyuridine
Rifampicin
Nalidixic acid
46. This is given together with Isoniazid for
patients with TB to prevent neurologic
side effects:
A.
B.
C.
D.
Rifampicin
Ethambutol
Pyridoxine
Pyrazinamide
47. The type of glass most suitable for
parenteral preparations is
A.
B.
C.
D.
Type I
Type II
Type III
NP
48. What is the titer value 0.05M calcium
chloride with 2 moles of water?
MW=142.9
A.
B.
C.
D.
•
3.57mg
7.15mg
73.5mg
53.7mg
49. This is the smallest tapeworm that
infects humans:
A.
B.
C.
D.
Taenia solium
Taenia saginata
Hymenolepsis nana
Echinococcus granulosus
50. Safety and Toxicity tests are conducted
using:
A.
B.
C.
D.
Rabbits
Dogs
White mice
Guinea pig
51. The process in which the exact
concentration of solution is determined
A.
B.
C.
D.
Neutralization
Standardization
Titration
Complexation
52. This is also known as the Giant
intestinal fluke:
A.
B.
C.
D.
Fasciola hepatica
Clonorchis sinensis
Fasciolopsis buski
Schistosoma japonicum
53. A spectrophotometer differs from a
colorimeter is that it is consists of:
A.
B.
C.
D.
Prism
Lamp house
Cell compartment
B and C
54. The crude fiber of a drug usually
consist of:
A.
B.
C.
D.
Cellulose
Cholesterol
Phytosterol
Lard
55. This is the diagnostic test for the
presence of Enterobius vermicularis:
A.
B.
C.
D.
Kato thick method
Kato-katz method
Scotch tape swab method
Brine flotation technique
56. The primary staining reagent of the
gram procedure is:
A.
B.
C.
D.
Methyl red
Carbol fuchsin
Crystal violet
Saffranin
57. Twenty tablets of ascorbic acid weighed
4.250g and a powdered sample of 0.3075g
used up 21.5mL of 0.1085N iodine solution.
What was the amount of Ascorbic acid per
dose of 2 tablets? Each mL of 0.1N iodine is
equivalent to 8.80mg of C6H6O6 (Ascorbic
acid). The amount is:
A. 283.7mg
B. 141.86mg
C. 0.2837g
D. A & C
58. This is the form of malarial parasite
that is taken up by the mosquito as it
bites on humans:
A.
B.
C.
D.
Gametocytes are the cells
taken by a biting anopheles
Sporozoites
mosquito from man. The
Merozoites
male and female
Trophozoites gametocyte will fuse in the
Gametocytes mosquito’s stomach into an
Oocyst that will give rise to
the sporozoites.
59. Adsorption indicators are used in:
A.
B.
C.
D.
Complexation reaction
Acidimetry
Volumetric precipitation
Alkalimetry
60. Iodimetry is what type of titration
A.
B.
C.
D.
Direct
Indirect
Residual
A&C
61. This is the malarial species that causes
the so called “Quartan Malaria”
A.
B.
C.
D.
P. ovale
P. vivax
P. malariae
P. falciparum
P. malariae produces fever
every 72 hours or three days
which is the so called Quartan
malaria,
P. Vivax and P. ovale produces
fever every 48 hours hence
called the Tertian malaria,
P. falciparum produces fever
every 36-48 hours which is also
known as Malignant tertian
malaria.
62. To measure the optical activity of a
sample, the instrument used is:
A.
B.
C.
D.
Polarimeter
Refractometer
Spectrometer
Flame photometer
63. The type of alkaloidal assay where the
total alkaloids are determine is:
A.
B.
C.
D.
Ultimate
Specific
Proximate
Precision
64. This is the ingested infective form of
protozoan parasites in humans:
A.
B.
C.
D.
Cysts
Merozoites
Trophozoites
Cytostomes
Trophozoites are
the motile form
(juvenile),
Cytostome is the
mouth from which
pieces of food is
ingested.
65. The unsaponifiable matter present in
animal fats is:
A.
B.
C.
D.
Cholesterol
Phytosterol
Lard
Wax
66. The infrared region of the
spectrometer used to identify a
substance uses a wavelength range of:
A.
B.
C.
D.
3-15μm
380-780μm
200-380μm
15-300μm
67. This organism causes a non-bloody
diarrhea:
A.
B.
C.
D.
Entamoeba histolytica
Giardia lamblia
Isospora belli
Strongyloides stercolaris
68. What is the other name of Koettsdorfer
number?
A.
B.
C.
D.
Acid value
Saponification value
Ester value
Iodine value
69. Using a spectrophotometer to measure the
concentration of a sample, the following
data were obtained absorbance (A) of the
standard solution was 0.55
A of the sample was 0.58
The concentration of the standard used was 16.5mcg
The concentration of the sample was:
A. 15.5mcg
B. 17.55mcg
C. 17.40mcg
D. 15.9mcg
70. Koplik’s spots seen among patients
with measles are usually localized in the:
A.
B.
C.
D.
Upper extremities
Lower extremities
Mouth
Scalp
71. Body louse is the vector for
A.
B.
C.
D.
Leptospirosis
Pinta
Epidemic relapsing fever
Meningitis
73. Aside from Praziquatel, this is also
given for tapeworm
A.
B.
C.
D.
Diethylcarbamazine
Ivermectin
Mebendazole
Niclosamide
73. A defect that may affect the function of
an object and therefore, may render the
product useless
A.
B.
C.
D.
Major defect
Minor defect
Critical defect
Ocular defect
74. Given a tablet thickness of 0.47cm,
what should be the acceptable tablet
range?
A.
B.
C.
D.
0.4465-0.4935cm
0.4230-0.5170cm
0.4348-0.5050cm
0.3225-0.5875cm
75. The oxidation number of Mn in KMnO4
A.
B.
C.
D.
+2
+1
+5
+7
76. If a sample of white wax is found to
have an ester value of 65.7 and a
saponification value 74.2, what is the
acid value of the sample?
A.
B.
C.
D.
8.5
86.5
186.5
56.5
77. Also known as Eosin Y
A.
B.
C.
D.
Dichlorofluorescein
Tetrabromophenolpthalein
Tetrabromofluorescein
Xylenol Orange
78. Calculate the weight of oxalic acid
required to prepare 1000mL of 0.5N of
the solution. MW=126
A.
B.
C.
D.
36.5g
63.5g
31.5g
23.5g
79. Determine the iodine value of an
unknown sample of oil weighed 0.21g if
26mL and 12mLof 0.1100N of sodium
thiosulfate are required for the blank and
residual titration respectively
A. 90
B. 93
C. 108
D. 200
80. Titer is an expression of concentration
in terms of:
A.
B.
C.
D.
Grams of solute per 100mL
Grams or mg of solute per mL
Grams per liter
A&C
81. The molecular weight of sulfuric acid is
98. Its equivalent weight is:
A.
B.
C.
D.
98
49
0.098
0.049
82. The oil from peppermint spirit can be
determined by using:
A.
B.
C.
D.
Cassia flask
Bobcock bottle
Pycnometer
Titration
83. Which of the following is an example of
aerobic organism?
A.
B.
C.
D.
Listeria monocytogenes
Chlamydia trachomatis
Staphylococcus aureus
Mycoplasma pneumonia
84. This spirochete is tightly coiled, thin,
and has a hook at its end
A.
B.
C.
D.
•
Vibrio
Borrelia
Leptospira
Treponema
85. A 4-year old kid complains of itchiness
in his anal area. Anal swab from this
patient will reveal larvae of which of the
following?
•
•
•
•
Leptospira interogans
Chlamydia trachomatis
Helicobacter pylori
Enterobius vermicularis
86. This species of Shigella is responsible
for the most infection on the milder side
of the spectrum of Shigellosis.
A. S. dysenteriae
B. S. sonnei
C. S. boydii
D. S. flexneri
87. Beer’s plot in spectrophotometry is
prepared to determine:
A.
B.
C.
D.
Absorbance of the sample
Wavelength to be used
Blank
Concentration of the drug substance
88. One of the following is NOT an in
process for tablet
A.
B.
C.
D.
Bioavailability
Weight variation
Hardness and thickness
Disintegration
89. The temperature used for ignition to
constant weight is:
A. 725 + 25˚C
B. 825 + 25˚C
C. 800 + 25˚C
D. 750 + 25˚C
90. Potency of a 100mg tablet at expiry
date
A.
B.
C.
D.
95mg
105mg
90mg
110mg
91. The ester value determination of
substance is applicable to the following,
EXCEPT:
A.
B.
C.
D.
Fats
Volatile oils
Alcohol
Fatty oil
92. To keep samples moisture free the
apparatus used is:
A.
B.
C.
D.
Dessicator
Furnace
Incubator
Oven
93. The indicator for EDTA titration against
CaCO3 is:
A.
B.
C.
D.
•
Thymol blue
Hydroxynaphthol blue
Methyl red
Methylene blue
94. Adsorption indicators are used in:
A.
B.
C.
D.
Complexation reaction
Acidimetry
Volumetric precipitation
Alkalimetry
95. Analysis where separation of the
constituents from the sample is done by
weighing the product is:
A.
B.
C.
D.
Volumetric
Gravimetric
Special
Gasometric method
96. The primary staining reagent of the
Gram procedure is:
A.
B.
C.
D.
Methyl red
Carbol fuchsin
Crystal violet
Saffranin
97. Which organism is suspected to have
infected a goat farmer who had
complained a fever of unknown cause?
A.
B.
C.
D.
Brucella militensis
Brucella abortus
Brucella suis
Bacillus cereus
98. Diphyllobotrium latum infection may
lead to the deficiency of which vitamin?
A.
B.
C.
D.
Vit A
Vit B6
Vit B1
Vit B12
99. All are extracellular parasite, except;
A.
B.
C.
D.
Enterobius
Trichinella
Strongyoloides
Ascaris
100. This sexually transmitted protozoan is
common among male homosexual
A.
B.
C.
D.
Giardia lamblia
Entamoeba histolytica
Faciola hepatica
Ascaris lumbricoides