CUTTING EDGE BIOMOLECULAR SCIENCE
2014 SFBBM SYMPOSIUM • MARSTRAND
Wednesday
Thursday
24 September
Friday
25 September
26 September
08:30-09:15
How dysfunctional replisomes signal cell cycle arrest
Peter Burgers, Washington University
09:00-09:45
Protein kinase CK2 - at the crossroads of signaling networks and
implications for pathological rewiring of regulatory pathways
David Litchfield, University of Western Ontario
09:15-09:45
Human mitochondrial DNA maintenance in
health and disease
Sjoerd Wanrooij, Umeå University
09:45-10:15
New fluorescence techniques reveal NK cell receptor dynamics at the
molecular level
Sofia Johansson, Karolinska Institutet
09:45-10:30
Round table discussion
10:15-10:30
Structure-based ligand design to overcome CYP inhibition in drug
discovery projects
Gisela Brändén, University of Gothenburg
Careers in research - why, how, when and where?
Virginia Zakian, Princeton University
Emma Sparr, Lund University
Henrik Zetterberg, University of Gothenburg
Marianne Quiding-Järbrink, University of Gothenburg
Chair: Elias Arnér
10:30-10:45
Importance of rigorous enzymology in drug discovery the case of PARP inhibitors
Herwig Schüler, Karolinska Institutet
10:45-11:00
Drug discovery at the single molecule level
Anders Gunnarsson, AstraZeneca R&D
10:30-11:15
Coffee and exhibition
Room ”Vinden”
11:00-11:30
Coffee and exhibition
Room ”Vinden”
11:15-11:30
Catalytic rates of yeast DNA polymerase ε
Rais Ganai, Umeå University
11:30-12:00
Biochemical properties of the essential
S. pombe Pfh1 helicase
Nasim Sabouri, Umeå University
11:30-11:45
Biochemical profiling of DNA binding in wild-type and mutant p53
with CETSA
Rebecca Dovega, Karolinska Institutet
12:00-12:15
UL52 primase interactions in the HSV-1 helicase-primase complex
are affected by antiviral compounds and mutations causing drug
resistance
Isabella Muylaert, University of Gothenburg
11:45-12:00
Transcriptional mutagenesis - p53 protein as probe of biological
effects
Kristian Dreij, Karolinska Institutet
12:15-12:30
A presentation of the MBB/SciLifeLab protein science facility
Tomas Nyman, Karolinska Institutet/SciLifeLab/PSF
12:00-13:30
Lunch
12:30-13:30
Lunch
12:55-13:00
Welcome to Cutting Edge Biomolecular Science
Elias Arnér, President SFBBM
13:30-14:00
Getting to the core of CorA - defining the molecular building blocks
of a magnesium channel
Mikaela Rapp, Stockholm University
13:30-13:45
Structural architecture and selectivity characteristics of protoncoupled peptide/drug transporters
Fatma Guettou, Karolinska Institutet
13:00-13:45
Pif1 family helicases promote replication fork progression
Virginia Zakian, Princeton University
14:00-14:30
Proteins regulating membrane shape and cell surface dynamics
Richard Lundmark, Umeå University
13:45-14:00
Live cell imaging of mitochondrial dynamics and function in
dendrites and spines
Kaliaselvan Krishnan, KTH
13:45-14:15
Biomarkers for Alzheimer’s disease - our most common brain
amyloidosis
Henrik Zetterberg, University of Gothenburg
14:30-14:45
Biophysical characterization of membrane-interacting
glycosyltransferases
Scarlett Szpryngiel, Stockholm University
14:00-14:45
The Svedberg prize ceremony and lecture
Lecture hall
Suggested transportation by public transport:
(Tickets are sold by Västtrafik and/or SJ.)
11:40-11:58
Train 3746 towards Uddevalla departs from Göteborg C.
Arrives at Ytterby station 11:58.
12:08-12:36
Bus ”Marstrand Express” leaves Ytterby station.
Arrives at Marstrand färjeläge (terminal) 12:36.
14:15-14:45
14:45-15:00
Compartmentalized single cell analysis - antibiotic susceptibility and Mechanisms of cellular uptake of the antisecretory peptide AF-16
protein screening
Maria Matson-Dzebo, Chalmers
Helene Andersson-Svahn, KTH
14:45-15:30
Coffee and exhibition
Check-in
15:00-15:30
Coffee and exhibition
Room ”Vinden”
15:30-15:45
Single molecule investigations of transcription factor kinetics living
bacterial cells
Johan Elf, Uppsala University
15:30-16:00
Lipid-protein co-aggregation in amyloid systems
Emma Sparr, Lund University
15:45-16:00
Simultaneous determination of Nrf2, HIF and NFκB activation at
single-cell resolution
Katarina Johansson, Karolinska Institutet
16:00-16:30
Successes and failures in structure-based discovery of
GPCR ligands
Jens Carlsson, Stockholm University
16:00-16:15
Desensitization of GPCRs - physiological and pharmacological
concentrations of angiotensin II yield distinct differences in AT1
receptor signaling
Kristoffer Bernhem, KTH
16:30-16:45
Studying bicelle morphology with NMR diffusion spectroscopy and
two-way data decomposition
Johannes Björnerås, Stockholm University
16:15-16:30
Some like it hot - biomolecule analytics using MicroScale
Thermophoresis
Nicholas Luzzietti, NanoTemper Technologies
16:45-17:00
Heme A synthase in bacteria depends on two extracytoplasmic
cysteine residues
Lars Hederstedt, Lund University
16:35-17:00
Annual Proceedings of SFBBM
Årsmöte för Svenska föreningen för biokemi, biofysik och
molekylärbiologi
17:00-17:15
Phosphoryl and sulfuryl transfer reactions - challenges in
interpreting experimental and theoretical data
Lynn Kamerlin, Uppsala University
17:00-19:00
Social activity
Meet up in hotel lobby
17:15-17:30
Sizing of spots at least seven times smaller than the resolution of the
LSM used by Scanning Inverse FCS
Stefan Wennmalm, KTH
19:00-20:00
Dinner
17:30-19:30
Poster session, mingle and exhibition
20:00-22:00
Poster session, mingle and exhibition
Room ”Vinden”
Room ”Vinden”
19:30
Conference dinner
14:45-15:30
Coffee and exhibition
Room ”Vinden”
14:54-15:45
Bus ”Marstrand Express” departs.
Arrives at Göteborg C / Nils Ericson Terminal
Tickets are sold by Västtrafik or SJ.
SFBBM
Svenska föreningen för biokemi, biofysik och molekylärbiologi
Swedish society for biochemistry, biophysics and molecular biology