PSORIASIS 2010
Congress of the Psoriasis International Network
PARIS, July 1-4, 2010
Palais des Congrès
Current Psoriasis
Situation in China
Zheng Min，M.D.
Dermatology Department
Second Hospital
Zhejiang University, School of Medicine
浙江大学医学院附属第二医院郑敏
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Practical organisation of Chinese
Psoriasis Network
National projects
opportunitis to develop international
collaborations on specific topics
other issues
Chairman Prof. Zhu Xuejun,
Chinese Dermatologist Association
Chinese Psoriasis Network
Six National Psoriasis Center
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Institute of Dermatology, Chinese Academy of
Medical Sciences and Peking Union Medical
College.Nanjing;
First Hospital Beijing Univerity.Beijing;
Second Hospital Zhejiang University.Hangzhou;
Huashan Hospital, Fudan University.Shanghai;
Xijing Hospital, Fourth Military Medical University;
Xi’an ;
Peking Union Medical College Hospital.Beijing.
Geographic Coverage of 46 hospitals in China
未覆盖区域
山西
贵州
四川
西藏
香港
台湾
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Practical organisation of Chinese
Psoriasis Network
National projects
opportunitis to develop international
collaborations on specific topics
other issues
National projects
World Psoriasis Day event
 Targeted Patients
Epidermological Investigation
 National Treatment Guideline
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Press conference focus on national psoriasis prevention and treatment on 29. Oct.
Prof. Zhu Xuejun, chairman of China Dermatologist Association, in Press conference in
International day of Psoriasis
46 hospitals in different cities of China
(2009.Nov.23-Dec. 12)
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Beijing
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4879 cases of psoriasis
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Shanghai
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Hangzhou
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New Data 2009
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46 hospitals in China
4879 cases of psoriasis vulgaris
Male, 61.14%; Female, 38.86%，
Male : Female=1.57 ：1
Mean age 40.49±22.11
Genetic epidemiology
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Family history of psoriasis: 22.84%
(1057/4628)
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62.53 % in first degree relatives
27.72 % in second degree relatives
9.76 % in third degree relatives
Peak age of first onset
male: 20~29 years
female: 10~19 years
Zhang XJ et al: Analyses of Genetic Epidemiology of Psoriasis Vulgaris
Chinese Journal of Dermatology 2000;33(6):383-385.
Psoriasis vulgaris may be a multigenic
inheritable disease and the genetic
factors play an important role in the
pathogenesis of psoriasis.
Zhang XJ et al: Analyses of Genetic Epidemiology of Psoriasis Vulgaris
Chinese Journal of Dermatology 2000;33(6):383-385.
Causative factor
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Psychological factor
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Infection, wound
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Alcohol, diet, smoking, drug
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Endocrine and metabolic disease
Relapse and aggratate
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Season, especially winter (83.36%)
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Psychological factor
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Pharyngolaryngitis or tonsillitis
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Alcohol and food
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Medicine and smoking
Releave Season
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Summer（90.56%）
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Spring
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Paracmasia: 14.06±37.93 m
Clinical Type of psoriasis
in China
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Psoriasis vulgaris: 4489（92.01%）
Guttae 26.09%
Plaque 57.01%
Mix
16.91%
Psoriasis pustulosa:
169 （3.46%）
Psoriasis erythroderma:
79 （1.62%）
Psoriasis arthropathica:
142例（2.91%）。
Comorbidities in psoriatic patients
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19.67%: 932/4737 have accompanied
disease
High blood pressure: 576（12.16%）
Diabetes: 237（5.00%）
Coronary heart disease:149（3.15%）
Hyperlipemia: 340（7.18%）
Rheumatoid arthritis: 61（1.29%），
Tumor: 40（0.84%）。
Management
Systemic therapy;
Topical therapy;
Patient education.
Systemic treatment
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79.55% (3809/4788)
Traditional Chinese Medicine 89.47%
Acitretin 22.06%
MTX
5.64%
Immunosupressants 14.02%
Steroids 13.30%
Others 27.59%
Systemic treatment
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Methotrexate 7.5mg/week
widespread plaque, senile person
Acitretin
0.5mg/kg.d
erythroderma and pustular psoriasis
Cyclosporin A 5mg/kg.d psoriasis arthritis
Corticosteroids.
Biologics
Alternative therapy TCM
Topical therapy
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90.34% (4283/4741)
Topical steroids: 85.59%
Vitamin D3 analogue: 31.64%
Topical retinoids: 27.01%
Salicylic acid: 18.98%
Coal tar: 14.57%
Anthralin: 3.34%
Topical TCM: 23.67%
Others: 25.40%
Physical therapy
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26.54%: 1244/4688
NB-UVB ＞50%
UVB
PUVA
Insurance and treatment costs
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71.2% patients have a social medical
insurance (non-commercial), and
7.43% patients attend other
commercial medical insurance
In the past 6 months, about 29.84%
went to see a dermatologist 6 times.
The mean fees is $101±2000, and
about $52±100 were paid by patients
themselves。
Insurance and treatment costs
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In the past 2 years, 7.07% patients were
accepted in the hospital and 0.21% were in
the hospital more than 6 times.
The duration in the hospital is
27.26±46.27d，mean spent is
$1100±1200，and the patients themselves
have to pay $600±1000
QOL
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18.73% patients were affected
severely, 29.45% moderately， and
37.56% slightly. Only 14.27% were
unaffected.
13.31% patients’ family expenditure
were affected greatly, 25.96%
moderately, 38.90% slightly and
21.82% unaffected.
More to do
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Update our National Treatment
Guideline according to the new data
from evidence based medicine:
National Disease Registration;
National Epi Invetigation;
International co-operation.
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Practical organisation of Chinese
Psoriasis Network
National projects
Opportunitis to develop international
collaborations on specific topics and
other issues
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Comparison study on the background
between Eastern and Western in
genetics and clinical pattern
background
Some mechanism study on traditional
Chinese Medicine on psoriasis
…….
THANK YOU !
Beijing
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Shanghai
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Hangzhou
Zhejiang Univ. School of Med.