Agenda
01 About Pollogen – Expect more
02 geneO+ Revolutionary skin care platform
03 OxyGeneo™ & TriPollar® – Technologies Overview
04 Clinical results and B&A
01
About Pollogen
Expect more
Pollogen develops & markets
advanced solutions for the
aesthetics market
As technology leaders, we
continuously challenge ourselves
to deliver innovation with
genuine added value for
aesthetic professionals.
We believe that every customer deserves to benefit
from the best of all worlds: safe, pleasant and noninvasive treatment, as well as long-lasting results that
can be seen and felt immediately
To contend with this challenge, we develop innovative
technologies, manufacture smart & user-friendly systems
and offer a broad variety of treatments with proven results.
Above all, we redefine the standards in the world of
aesthetics and are committed at all times to give you more…
Pollogen - Expect more
More Global presence
Over 60 distributors worldwide
More Results
Clinically proven
Peer reviewed papers in leading medical journals confirming the
safety and effectiveness of Pollogen’s technologies.
More Partnership
With Pollogen, you have a true partner
Pollogen will accompany you the whole way and provide you
with a comprehensive range of services of exceptional standard:
• Updates on new technological developments
• Product training
• Clinical support
• Technical support
• Supply of marketing materials
• Direct communication with the sales manager
• Comprehensive marketing consulting and support
More Opportunities
From small niche to a $4.4B market
In the past decade, the global
aesthetics market has grown at a
double-digit pace, developing from a
small niche to a $3.3B market in 2010.
Despite the global recession,
consumers continue to invest in
beauty treatments, & the market is
expected to reach $4.4B in 2015.
Source: BCC Research
More Innovations
Pollogen® is a world leader in innovative, clinically proven,
aesthetic solutions for facial treatments and body sculpting.
02 Revolutionary skin care platform
Introducing…
Where superior aesthetic treatments meet RF technology
to create a breakthrough skin-care platform
Product Overview
Designed with the aesthetic professional in mind, geneO+ integrates
Pollogen’s new patented OxyGeneo technology with renowned
TriPollar technology.
geneO+ delivers superior skin nourishment and oxygenation together
with clinically proven anti-aging results.
The combination of TriPollar RF and
OxyGeneo improves skin quality both
at the epidermis and dermis layers
delivering long lasting results
Business benefits for clinics
• New treatment options and increased customer flow
• Position your clinic as a leader and gain an advantage over your
competitors with cutting-edge technology and design
• Increased income & quick ROI
•
•
•
•
Affordable product entry price
Charge premium price for treatments
Increase repeat customers and customer loyalty
geneO+ treatments are an ideal opportunity to upsell home use
cosmetics/treatments
Join the success! Be one of the thousands of clinics
worldwide that offer patented TriPollar & OxyGeneo
Technologies!
OxyGeneo™ and TriPollar®
combination protocol
Advantages of OxyGeneo & TriPollar
OxyGeneo - A 3 in 1 skin care treatment to actively nourish, vitalize
and hydrate the skin:
• Exfoliation of the outer skin layer
• Infusion of revitalizing nutrients
• Oxygenation of skin generated from within
TriPollar RF – The 3rd generation RF anti-aging technology
• Wrinkle reduction
• Skin tightening
• Safe, effective and pleasant
• Immediate and long term results
Protocol according to indication
Treatment focused on fine lines and wrinkles • 6 weekly sessions, followed by monthly touch up session.
• First OxyGeneo (NeoRevive or NeoBright ~8 min) and then
TriPollar (full face ~30 min)
• The OxyGeneo treatment exfoliates the stratum corneum and
enables better impact of the RF
Treatment focused on improving skin texture and nourishment
• 6 weekly sessions, followed by monthly touch up session
• First TriPollar (full face ~20 min) and then
OxyGeneo (NeoRevive or NeoBright ~8 min)
• The RF treatment increases blood circulation and improves
penetration of the active ingredients of the gel.
Note: both protocols can be finalized with NeoMassage session
(~5 min)
03
OxyGeneo & TriPollar
Technologies Overview
OxyGeneo Technology
Natural hot springs have been known through the ages for
their therapeutic benefits, allowing minerals to be effectively
absorbed through the skin to revitalize body cells.
Similar to the natural hot springs effect, OxyGeneo™ is the
world’s first technology that significantly accelerates the
absorption and optimal utilization of nutrients by the skin
using our exclusive Capsugen and specialized Gels.
OxyGeneo Technology
• Harnesses the body's natural mechanisms to deliver 3 effective
treatments simultaneously:
• Exfoliation of the outer skin layer
• Infusion of revitalizing nutrients with Pollogen’s unique skin care
formulas
• Natural skin Oxygenation from within
• OxyGeneo’s “3 in 1” approach creates an optimal environment for the skin
to absorb essential nutrients both during and after treatment.
• OxyGeneo uses disposable and easy to sterilize components that ensures
maximum hygiene during every treatment.
Each treatment includes a unique
combination of Capsugen™
and gels developed by Pollogen
from natural ingredients
OxyGeneo - How it works
• Pollogen’s unique Capsugen™ is composed
of sodium bi-carbonate and citric acid.
Our exclusive gel contains natural active
ingredients.
• When the effervescent Capsugen™ comes
in contact with the exclusive treatment gel
on the skin surface an immediate reaction
is triggered.
• This reaction induces the OxyGeneo effect
that simultaneously:
• Exfoliates the skin’s outer layer
• Prepares it for infusion of active
ingredients
• Infuses the natural active ingredients
deep into the epidermis
• Enriches the area with O2 rich blood
OxyGeneo - How it works
OxyGeneo produces countless minute
CO2 bubbles which gently burst on the
skin surface.
• The OxyGeneo applicator is designed
to degas the CO2 bubbles from the gel
and infuse them into the epidermis.
• The applicator’s frequency and
amplitudes are specifically
designed to:
• Produce a kinetic force that optimizes
the chemical reaction generating CO2
bubbles and:
• Enable optimal penetration of CO2
bubbles into the epidermis.
OxyGeneo - How it works
The outcome is a CO2 rich environment
on the skin's surface*.
The body responds by:
• Sending O2 rich blood to the area
• Increasing capillary blood flow
• Increasing metabolism of the skin cells
The desired result: Optimal absorption of
the active ingredients by the skin
* The chemical reaction between the Capsugen and the gel that generates CO2:
OxyGeneo and The Bohr Effect
C02 rich environment & infusion of
active ingredients
Oxygenation of skin cells &
skin rejuvenation
This C02 rich environment induces a physiological response called the BOHR EFFECT leading to increased
tissue oxygen.
TriPollar® Technology
• TriPollar 3rd generation RF technology:
• TriPollar utilizes RF energy to induce collagen & elastin regeneration
in the dermis layer.
Leading to:
• Smoother and tighter skin
• Fine lines and wrinkles reduction
• Improved skin texture
Pollogen’s Breakthrough TriPollar Technology
• 3rd generation TriPollar RF - applies conductive RF to the skin
via 3 or more electrodes
• Energy is focused in the target area for optimal effect – not
requires cooling
• Volumetric heating generates clinical effect
• The most pleasant RF treatment due to focused energy field
allowing low power consumption
TriPollar® Preparation Gel
• The matching fluid for the TriPollar
treatment is the TriPollar Preparation Gel.
• The TriPollar preparation gel should be
applied on the treatment area before
starting the TriPollar RF treatment.
• The gel lubricates the area and allows
smooth movement of the applicator on
the skin.
• Has a high electrical resistance forcing the
electrical current to enter deep into the
skin, avoiding the current from flowing on
the surface and creating sparks
04 Clinical Results and B&A
Clinical studies and B&A
EVALUATION OF SAFETY AND EFFICACY OF THE
TRIPOLLAR® TECHNOLOGY FOR TREATMENT OF
WRINKLES
Steven D. Shapiro MD & Amos Leviav MD
Study Objective:
• To evaluate the safety of the apollo™ system for treatment of wrinkles and rhytides.
• To evaluate the efficacy of the apollo™ system for treatment of wrinkles and rhytides.
Methods:
Subjects: 37 Female subjects were recruited - 37 completed all treatments, 3 lost to followup due to travel or change of residence.
Visits: 8 Weekly treatments, Follow-Up at 1 month and 3 months after treatment 8.
Two sites:
― Steven Shapiro MD (Dermatologisit) – Gardens Dermatology and Cosmetic Surgery
Center, Florida US
― Amos Leviav MD (Plastic Surgeon) - Kaplan Hospital, Israel
STUDY # 1
Results
Safety
― No unexpected adverse side effects were detected or reported.
― All subjects reported no pain or mild pain during the treatments.
Efficacy
― A downgrade of at least 1 score in Fitzpatrick scale was found in 94% (1st
reviewer) and 97% (2nd reviewer) of study subjects.
― Subjects satisfaction questionnaires revealed high level of satisfaction.
― PI’s scoring of subjects’ facial skin appearance at baseline and 3 at month FU
demonstrated average reduction of 1.55 (Dr. Leviav) and 2.4 (Dr. Shapiro) .
Conclusions
The results of this study clearly indicate that the TriPollar technology offers a
non-invasive, effective, safe and virtually painless wrinkle and rhytides reduction
treatment.
STUDY # 1
Sample photos: A 51 years old female
Before - Baseline
After - 3M following 8 Tx
STUDY # 1
Sample photos: A 42 years old female
Before- Baseline
After - 3M following 8 Tx
STUDY # 1
Sample photos: A 59 years old female
Before- Baseline
After - 3M following 8 Tx
STUDY # 1
Sample results: A 61 years old female
Before- Baseline
After - 3M following 8 Tx
STUDY # 1
CLINICAL EXPIRIENCE WITH A TRIPOLLAR®
RADIOFREQUENCY SYSTEM FOR FACIAL AND BODY
AESTHETIC TREATMENTS
Dr. Alex Levenberg
Study Objective:
To evaluate the safety and efficacy of the TriPollar® for non-invasive
treatment of localized excess fat and facial tightening
Materials and Methods:
• 37 female patients
• Average of 7 treatments for wrinkles, laxity and circumference reduction on
different facial and body areas.
• Evaluation methods:
o Facial results objectively analyzed with Primos 3D imaging system
o Photographs – evaluate facial results
STUDY # 2
Results:
•Average circumference reduction, in main body areas (abdomen,
buttocks, thighs): 3.6 ± 2.4 cm (P < 0.0001)
• Abdomen: 4.5 ± 2.7 cm, max 10.5 cm
• Buttocks: 3.1 ± 1.7 cm, max 5 cm
• Thighs: 2.4 ± 2.0 cm, max 6.4 cm
•Improvement of perioral and periorbital wrinkles was achieved
Before
After 8 Tx
STUDY # 2
Clinical studies and B&A
OxyGeneo™ TECHNOLOGY CLINICAL STUDY
Study was performed by an independent 3rd party:
Physiological Models
Study Objective
• To understand the OxyGeneo™ mechanism by evaluating its effects on
blood perfusion, tissue CO2 and O2 levels and the thermal effect of the
treatment.
Study method
• Blood perfusion, tissue CO2 and O2 levels and thermal imaging profiles were
measured on different body areas of 11 subjects.
• Base line control measurements were taken before treatment.
• Treatment was performed for ~10 minutes.
STUDY # 1
OxyGeneo™ TECHNOLOGY CLINICAL EFFECT
CO2 and O2 levels as measured before and after treatment:
Effect of Oxygeneo ™ treatment
on tissue gasses
TCpCO2TCpO2 (mmHg)
80.0
70.0
60.0
50.0
TcpCO2
40.0
TcpO2
30.0
20.0
10.0
0.0
control
after
CO2 levels (in blue) returned to baseline values while the O2 (in green)
levels rose above the baseline levels 15 min after treatment.
STUDY # 1
OxyGeneo™ TECHNOLOGY CLINICAL EFFECT
Effect of Oxygeneo ™ treatment
on tissue on blood perfusion
300%
250%
perfusion p-p
% of control
200%
perfusion max
150%
100%
50%
0%
control
immediate
after
• Increase in blood perfusion immediately after the treatment and a gradual return
to base line levels.
• 15 min after treatment the values were higher than the baseline.
• These parameters demonstrate an increase in flow and intensity
STUDY # 1
OxyGeneo™ TECHNOLOGY–
NEOREVIVE CLINICAL STUDY
Study method
• 20 female volunteers, ages 32 - 58 were included in the study.
• 6 weekly facial treatments were conducted.
• Treatment was performed for ~10 minutes.
• The procedure was performed by a beautician and supervised by a
dermatologist.
• The following assessments were included:
o
Auto evaluation (questionnaires to volunteers)
Evaluation Scale:
1. Repulsive
2. Not satisfactory
3. Acceptable
4. Good
5. Excellent
o
o
Evaluation by professional expert (dermatologist)
B&A photographs
STUDY # 2
NeoRevive® Results
STUDY # 2
NeoRevive® Results
before
after
• Enhancement of skin's pebbled appearance (elastosis).
• The diffuse netted pigmentation of the encircled area has almost cleared.
• The region looks more uniform and shiny.
STUDY # 2
More B&A
TriPollar Technology - Immediate Results
Facial Skin Tightening after 1 treatment
Non-treated
side
Treated side
Courtesy of Dr. Stavros Eleftheriou, Surgical Art Clinic, Larnaca, Cyprus
50
TriPollar Technology - Long Term Results
Facial Skin Tightening after 5 treatments
before
after
Pollogen in house collection – Tel Aviv, Israel
51
OxyGeneo treatment results
Fine lines improvement
Immediately after 1 NeoRevive treatment
before
GFM PRIMOS portable 3D measuring system version 5.6
Same client as on previous slide
after
OxyGeneo treatment results
Skin smoothness demonstrated by (x500 ) Microscope
Immediately after 1 NeoRevive treatment
before
after
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SYDNEY AUSTRALIA
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