Debilitating Eye Diseases

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Debilitating Eye Diseases

By

Ma. Teresa G. Martinez, M.D.

International Eye Institute

St. Luke’s Medical Center

Diabetes mellitus

Hypertension

Glaucoma

Age-Related Macular Degeneration

Retinal Detachment

Uveitis

Diabetic Retinopathy

Non-Proliferative mild, moderate, severe, very severe

Proliferative early high risk

S/Sx painless blurring of vision (gradual or sudden) retinal changes

Treatment blood sugar control panretinal photocoagulation pars plana vitrectomy

HPN Retinopathy

Modified Scheie Classification

Grade 0 No changes

Grade 1 Barely detectable arterial narrowing

Grade 2 Obvious arterial narrowing with focal irregularities

Grade 3 Grade 2 plus retinal hges and/ or exudate

Grade 4 Grade 3 plus disc swelling

S/Sx blurring of vision retinal changes

Treatment

Blood pressure control

Complications

Central Retinal Artery Occlusion

Branch Retinal Artery Occlusion

Central Retinal Vein Occlusion

Branch Retinal Vein Occlusion

Central Retinal Artery Occlusion

Caused by atherosclerosis-related thrombosis (ophthalmic artery)

S/Sx acute and profound loss of vision pale retina cherry red spot

Treatment

Immediate (within 90 mins)

↓ IOP by ocular massage

Anterior Chamber Paracentesis or

Retrobulbar Anesthesia

Inhalation Therapy (95% O2/ 5% CO2)

Oral Acetazolamide & Aspirin

Branch Retinal Artery Occlusion

Most commonly caused by emboli

Cholesterol, Platelet-fibrin, Calcific

Other associations: trauma, coagulation disorders, sickle cell disease, oral contraceptives, mitral valve prolapse, inflammatory &/or infectious etiologies, connective tissue disorders

S/Sx

Acute & severe altitudinal visual field defect

Pale retina in the area supplied by the affected artery

Treatment

Mgt is directed toward determination of systemic etiologic factors

No specific ocular therapy proven to improve visual prognosis

Central Retinal Vein Occlusion

Non-Ischaemic (most common) moderate loss of visual acuity

FA shows venous stasis but good retinal capillary perfusion

50% - normal or near normal visual acuity

Chronic Cystoid macular edema – poor visual acuity

Ischaemic

Severe loss of visual acuity

Marked tortuosity & engorgement of retinal veins

Retinal hemorrhages, Cotton wool spots

Severe optic disc edema & hyperemia

Visual acuity is permanently impaired

Monthly follow-up for 6 months

(+) neovascularization – PRP treatment

Tx of associated medical condition

Branch Retinal Vein Occlusion

Sudden blurring of vision

Metamorphopsia or relative visual field defect

Dilated & tortuous veins, hemorrhages, edema, cotton wool spots

Complications- chronic macular edema & neovascularization

Within 6 mos 50% of eyes w/ collaterals will have better visual acuity

Glaucoma

Increase in IOP, Optic Nerve changes,

Visual Field defects

Types:

Congenital, Infantile, Juvenile

Open Angle (Primary, Secondary)

Closed Angle (Primary, Secondary)

Early Disc Changes

Advanced Disc Changes

S/Sx

Decrease or loss in peripheral vision, eye pain with or without headache, eye redness, haloes around light

Optic Nerve changes

Treatment

Medical – oral, IV, eyedrops

Surgical

Laser or Cryotherapy

Age-Related Macular Degeneration

Severe central visual acuity loss in one or both eyes

Types:

Nonneovascular

Neovascular

Nonneovascular Neovascular

S/Sx :

Decrease or loss in central visual acuity

Treatment

Education & follow up

Micronutrients

Laser treatment (PDT)

Intravitreal injection of steroids

Intravitreal injection of anti-VEGF

Retinal Detachment

Types:

Rhegmatogenous – liquefied vitreous passing through a retinal break into the potential space between the sensory retina and the RPE

Tractional –caused by proliferative membranes that contract & elevate the retina

Exudative – caused by retinal or choroidal diseases in which leakage of fluid accumulates beneath the sensory retina

S/Sx: light flashes, wavy or watery vision, veil or curtain obstructing vision, shower of floaters that resemble spots, bugs or spider webs & sudden decrease of vision

Treatment

Surgery : Scleral Buckling

Pneumatic retinopexy

Cryotherapy, Laser or Diathermy

Vitrectomy

Uveitis

Inflammation of the uveal tract

Types:

Anterior

Intermediate

Posterior

Panuveitis

Posterior Uveitis

Anterior Uveitis

S/Sx floaters, blurring of vision, eye redness, eye pain, systemic manifestations anterior chamber findings, retinal changes

Treatment steroids immunosuppressives surgery

Legal Blindness

Visual acuity of 20/200 or worse in the better eye w/ corrective lenses (20/200 means that a person at 20 ft from an eye chart can see what a person w/ normal vision can see at 200 ft)

OR

Visual field restriction to 20 degrees diameter or less (tunnel vision) in the better eye.

Visual Acuity

Snellen Chart

Visual Fields/ Perimetry

Fluorescein Angiography

B-Scan Ultrasound

Optical Coherence Tomography

THANK YOU

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