WELCOME
CENTRAL LEPROSY TEACHING
AND RESEARCH INSTITUTE,
TIRUMANI,CHENGALPATTU
1
HISTORY
1924
Lady Wellington Leprosy Sanatorium at Tirumani
1924 to
1939
Managed by Church of Scotland. Dr. Paul Brand devoted
his life for the reconstructive Surgery
1946
Before Independence, Mahatma Gandhi Father of our
Nation visited the land of Tirumani. He gave written
message of blessing to the patients of the Sanatorium
and wished well to the staff.
SIGNATURE AND GREETINGS OF MAHATMA GANDHIJI
Significance of 30th January
 on 30.01.1946 – Father of the Nation visited CLTRI
Coincidentally, he died on 30.01.1948.
 30th January every year celebrated as Anti Leprosy Day.
HISTORY
05-01-1955
CLTRI was established by Government of India under
a Governing Body
1957- 1966
Dr. Dharmendra famous Leprologist was associated
with CLTRI as Director from 1967 to 1971 he was
Emeritus Medical Scientist of CLTRI.
1967- 1971
Significant Contribution :- Lepromin Test
Standardization of DDS (Diamino Diphenyl Sulphone)
a drug used for treating leprosy patients.
1974
CLTRI became a subordinate office of DGHS under
MOH&FW
1978-1983
Standardization of MDT (Multi Drug Therapy ) done
in this Institute.
1991
Nodal Centre for Thalidoamide drug therapy for ENL
(Erythrosom Nodosum Leprosom) reaction Cases.3
OBJECTIVE
 To undertake research into basic problems relating to the
occurrence and spread of leprosy and its control.
 To train manpower necessary to implement NLEP.
 To provide specialized services in the area of diagnosis,
reaction, relapse and Reconstructive surgery in Leprosy.
 To monitor and evaluate National Leprosy Eradication
Programme.
Additional Responsibitiy given in 2005 after Elimination of
Leprosy
CBHI Training
RNTCP Operational Research
IDSP Training
5
AREA OF CLTRI
Total Land of CLTRI
-
560.83 Acres
Institutional Buildings
-
66.53 Acres
Residential Buildings
-
28.72 Acres
Vacant Land
-
190.58 Acres
Land Given to HLL
(for proposed Medipark
on 20-03-2009 by MOHFW)
-
275 Acres
6
BUILDING
1.HOSPITAL BLOCK :
 Out Patient Unit
 Main Hospital -124 Bedded Hospital
 Sick Room
 Medical Investigation Ward
 Surgical Ward with X-ray department & Operation
theatre
 Physiotherapy Block
 MCR and Footwear Unit
 Centralised Kitchen
 Laundry
 Centralised Stores
7
BUILDING (Continued)
2.
ADMINISTRATIVE BLOCK
a. Administration
b. Laboratory & Animal House
c. Library
d. Epidemiology
3.
HOSTEL
a. Scientist Hostel -
18 Rooms
b. Students Hostel -
18 Rooms
c. Canteen
8
STAFF STRENGTH – STATUS REPORT
Sl.
No.
1
Total
Strength
Filled
Vacancy
Vacancy
Percentage
A ( Medical)
Specialist
15
3
12
87%
GDMO
11
6
5
45%
Group
2
A- Non
Medical
3
0
3
3
B- Gazetted
5
2
3
4
B- NonGazetted
19
14
5
5
Group C
117
84
33
28%
6
MTS
80
56
24
30%
250
165
85
34%
TOTAL
66 %
34 %
100%
60%
26%
9
Budget Estimate 2012-13
S.No.
HEAD
PLAN
10%
Balance
reduction in Budget
Non-plan*
NON-PLAN
1
Salaries
0
84150
0
84150
2
Wages
0
1400
0
1400
3
Overtime allowance
0
10
1
9
4
Medical Treatment
0
750
75
675
5
Domestic Travel Expenses
500
300
30
270
6
Office Expenses
2200
2020
202
1818
7
Publication
0
10
1
9
8
Other Administrative Expenses
250
0
0
0
9
Supplies and Materials
3500
2800
280
2520
10
Minor Works
1550
0
0
0
11
Scholarships /Stipend
0
300
30
270
12
Other charges
0
10
1
9
13
Motor Vehicles
0
450
45
405
14
Machinery and Equipment
1500
300
30
270
9500
92500
695
91805
TOTAL
11
Wards
Nursing
Section
Medical
Record
Section
Out Patient
Department
12
• Expert Management of reactions with Thalidomide,
Relapses/Drug Resistance etc.
• Teaching activities in leprosy to Undergraduates,
House
Surgeons
of
Medical
Colleges,
NMS
Supervisors and Nurses.
• Collection and study of relapse/recurrence cases
in leprosy.
13
On Going research activity
Drug Resistance
using Mouse foot Pad
Surveillance
14
Out-Patients particulars for the Last 5 years
2008-09
2009-10
2010-11
2011-12
2012-13
(Till Oct )
1
No. of new
Cases attended
OPD
64
104
74
90
48
2
No. of old
Cases attended
OPD
7155
7220
6192
6094
3353
3
No. of patients
attended OPD
from GLC block
2680
2074
1514
1694
776
4
No. of other
Cases (NCL)
Attended OPD
2224
1748
1441
1161
775
5
Total no. of
patients seen
in OPD
12123
11146
9221
9039
4952
GLC - Government Leprosy Centre
NCL - Not a Case of Leprosy
15
Surgical Unit
Physiotherapy Section
Artificial Limbs &
Footwear Section
X-ray Section
Micro-cellular Rubber
16
Surgical (cont.)
The Basic functions:
• Reconstructive Surgery
• Patient care activities.
• Teaching and Training Programs.
• Research.
17
Physiotherapy Section
Physiotherapy Services to PAL.
Various Teaching and Training programs.
Counselling & Health Education.
Facilities Available





Wax Bath,
Electrical Muscle Stimulator,
Inter Ferential Therapy,
Ultra Sonic Therapy
Traction Table.
18
Artificial Limbs & Footwear Section
 Footwear
patients
and
Prosthetic
to
the
Leprosy
Micro-cellular Rubber
 Small Production unit - Micro-Cellular Rubber
sheets (2000 sheets per annum)
 Providing MCR sheets to other states
19
Details of Major and Minor Surgery Done for the Last 5 years
S.
No
Surgeries
2007-08
2008-09
2009-10
2010-11
2011-12
Major Surgeries –(Reconstructive Surgery)
1.
Claw finger correction
7
7
14
6
8
2.
Claw thumb correction
3
5
5
5
1
3.
Wrist drop Correction
-
-
1
1
-
4.
Drop Foot Correction
5
1
-
6
-
5.
Lagapthalmos Correction
-
1
2
-
-
6.
Surgical Decomposition of
Nerves (Ulnar Nerve, Median
Nerve, Posterior Nerve)
4
1
2
3
-
7.
Amputation (Below Knee &
Below Elbow Amputation)
4
2
-
-
-
Minor Surgeries
8.
Ulcer Surgery
53
16
20
5
-
9.
Miscellaneous like Biopsy, MTH
Resection, Calcaneal shaving,
lagopthalmus, Skin Grafting,
Cystectomy etc.
18
4
6
6
-
Physiotherapy Activities for the last 5 year
S.N Activities
o
1.
New Case
2.
Assessments
3.
2007-08
2008-09
2009-10
2010-11
2011-12
70
55
77
51
195
973
895
708
530
789
Hand
Exercises
1905
1823
1742
1755
1943
4.
Foot
Exercises
857
797
737
714
749
5.
Wax Therapy
1845
1741
1698
1598
1740
6.
Splints
460
416
778
309
407
7.
General
Cases
91
60
67
52
71
Footwear and Prosthetic Supplied for the last 5 year
S.
No
2007-08
2008-09
2009-10
201011
2011-12
1234
1119
1199
942
500
1.
Simple and
Modified Micro
cellar Rubber
Sandals (in pairs)
2.
Orthotic and
Prosthetic
Appliances(in no’s)
23
21
25
28
5
3.
Major repair of
Orthosis and
Prosthesis (in no’s)
8
4
13
12
1
4.
Modifications Arch
Support and
Metatarsal Bars
(in no’s)
144
115
171
93
54
Division of Epidemiology
& Statistics
Monitoring
&
Evaluation
Unit
Statistics
Technical
Training
Library
Electronic
Data
Processing
Unit
23
Division of Epidemiology & Statistics
 CLTRI Website was created by our unit.
 Website for our institute was hosted in NIC
server (http://cltri.gov.in/).
 Logo for our Institute was designed.
 Inventory Management Software was developed.
 Consultancy services to the BCGVL, Guindy,
Chennai for creation of website and Inventory
management system.
24
Monitoring & Evaluation of NLEP
Activities
Monitoring & Evaluation of NLEP Activities among
Tamil Nadu, Karnataka, Kerala and Lakshawdeep
states/UT was carried out.
Visits Made for Monitoring Activities
 Lakshadweep Islands - 2000 population of school
children were Examined on January 2012.
 Tamil Nadu, Karnataka, Pondicherry States/UT for
planning M & E Activities.
 M & E conducted in Erode District, Tamil Nadu.
Surveillance Activities
Phase I of the Activity Study of the Household and
Neighbourhood Contacts of newly Reported Leprosy
cases in the CLTRI OPD from Thirukalukundram
Taluk area work was carried out during October
2011.
Phase II of the Activity is started on August 2012
and completed on September 2012
Analysis of the collected data is under process.
PROPOSALS
SFC
proposal
for
Strengthening
of
CLTRI
was
Prepared and submitted in DGHS (17 Oct 2012).
Operational Research Study to ascertain the reasons
for High Endemicity in 24 districts of 3 states
(Andhra Pradesh, Gujarat, Karnataka) was send to
CLD(31 May 2012).
Data Analysis
 OPD Data -New case attending CLTRI OPD for the
past 2 year were entered and analysed.
 Spatial Distribution of (Geographical Information)
of New cases attending CLTRI was prepared.
 Monthly progressive Report from districts of
Tamil Nadu, Andhra Pradesh and other states
were received and entered into Computerised
Simplified Information System (CSIS).
 Analysis of Reaction Case data is under process.
Training Activities
• State/District Leprosy Officer (SLO/DLO)
(5 days)
=
3 batches
• Medical Officer Training Course (5 days)
=
2 batches
• Non-Medical Health Supervisor’s (2 months) =
2 batches
• Skin smear Technician Training (5 days)
=
1 batch
• Laboratory orientation Training (BCG Staff)
=
2 batches
• Final MBBS students
=125 students
(one day visit)
• CRRI Training (5 days )
=110 Trainees
• Tertiary case management of Leprosy (10 days) =
• Inplant training in Microbiology &
Molecular Biology to Biotechnology students
1 batch
= 1 batch
29
Library
• Books
-
3278
• Journal
-
4409
• Periodicals
Foreign journals
-
Indian Journals
-
24
09
30
Workshop/Conference / Training
Attended
• Dr. V.C.Giri Assistant Director (Epid) attended
HIVCONGRESS 2012, Held at Mumbai from 16th to 18th
March 2012, Presented one Research paper and Two
paper by Co-authors in scientific session.
 Attended RTI Act for Public Information Officer
training at ISTM, New Delhi –August 2012
 Published 2 paper in International Journals.
• Dr. V.C.Giri, AD (Epid) & Dr. R. Veerkumaran, CMO
delivered lectures in Leprosy CMC organised by
Tirunelveli Medical College, Tirunelveli, Tamil Nadu.
• Mr. U. Aravindan, Statistical Investigator Gr. II attended
training in Statistical Analysis system (SAS) training
held at Christian Medical College, Vellore, Tamil Nadu.
Biochemistry
Hematology &
Microbiology
& Animal
Immunology
& Molecular
House
Biology
Clinical
Sterilisation
Pathology &
Histopathology
32
 Investigation for Leprosy related and
other Routine Investigations
 Basic and Applied Research activities
in Leprosy.
 Research
in
field
of
Diagnosis,
Molecular Biology, Drug therapy, Animal
studies in the field of Leprosy etc.,
33
On going Research projects:
 Study on surveillance of Drugs [rifampicin and
dapsone]
resistance,
among
smear
positive
multibacillary leprosy cases
 Detection
of
fumonisin
producing
Fusarium
species from rice seeds by polymerase chain
reaction.
 Variable number tandem repeats VNTRs finger
printing
as
an
Epidemiological
marker
for
Mycobacterium leprae haplotyping
34
Laboratory Investigations in the Last 5 years
S.
No
DEPARTMENTS /
SECTIONS
200809
200910
201011
201112
201213
1
Clinical Pathology & Skin
Smear
1233
1010
831
1168
669
2
Hematology & Serology
2255
3316
3000
3767
1980
3
Microbiology
262
397
100
129
82
4
Histopathology &
Molecular biology (Routine
&
Research activities)
483
4
71
331
5
Biochemistry
1705
1705
3130
3244
1463
6
Animal Position in the
Animal House
1. Balb/C Mice Inbred Strain
2. Swiss Albino Mice Inbred
Strain
3. Rabbit …
…
4. Rat
…
…
5.Sheep
323
269
6
14
323
269
6
14
548
496
4
548
496
4
548
496
4
35
Scientific Publications in last 1 year
 Detection of mutations in folp1, rpoB and gyrA genes of M. leprae
by PCR- direct sequencing--a rapid tool for screening drug
resistance in leprosy. Lepr Rev. 2011 Mar;82(1):36-45.
 OXA
beta-lactamase-mediated
carbapenem
resistance
in Acinetobacter baumannii. Indian Journal of Medical
Microbiology, Vol. 29, No. 3, July-September, 2011, pp. 269274
 Detection of Amp C genes encoding for beta-lactamases in
Escherichia coli and Klebsiella pneumoniae. Indian Journal of
Medical Microbiology, Vol. 30, Issue 3, 2012, pp. 290-295
 blaIMP AND blaVIM Mediated Carbapenem Resistance in
Pseudomonas and Acinetobacter species in a Tertiary Care Hospital
in India. The Journal of Infection in Developing Countries,
October 2012.
36
37
38
Phase I:
9 cluster are surveyed out of 18 clusters
2531 population was Examined
13 Cases case were found. NCDR= 51.36 per 10000
Adult
Child
Total
Paucibacillary (PB)
6
3
9
Multibacillary (MB)
4
0
4
Phase II:
9 cluster are surveyed out of 18 clusters
3702 population was Examined
13 Cases case were found. NCDR= 35.11 per 10000
Adult
Child
Total
Paucibacillary (PB)
6
3
11
Multibacillary (MB)
2
0
2