1. Product Name
ENDEAVOR
Pymetrozine
Pymetrozine 92%TC,
Pymetrozine 50% WDG
Insecticide
NOMENCLATURE
Common name pymetrozine (BSI, pa EISO)
IUPAC name (E)-4,5-dihydro-6-methyl-4(3-pyridylmethyleneamino)-1,2,4-triazin3(2H)-one
Chemical Abstracts name (E)-4,5-dihydro6-methyl-4-[(3pyridinylmethylene)amino]-1,2,4-triazin3(2H)-one
CAS RN [123312-89-0] Development
codes CGA 215944 (Ciba-Geigy)
Pymetrozine: MAMMALIAN TOXICOLOGY
Oral Acute oral LD50 for rats 5820 mg/kg.
Skin and eye Acute percutaneous LD50 for
rats >2000 mg/kg. Non-irritating to the
skin and eyes (rabbits). Not a skin
sensitiser to guinea pigs. Inhalation LC50
(4 h) >1800 mg/m3 air.
The lower the
LD50 number,
the more toxic.
How toxic a
substance is to
mammals.
Comparisons:
Endeavor LD50 = 5280 mg/kg body weight
Nicotine LD50 = 50
Caffeine LD50 = 200
2,4D LD50 = 375
Aspirin LD50 = 750
Malathion LD50 = 885
Table Salt LD50 = 3320
Roundup LD50 = 5600
Pyrethrum LD50 = 370
Rotenone LD50 = 60
How toxic something is to
organisms in the environment.
Pymetrozine: ECOTOXICOLOGY
Birds Acute oral LD50 for bobwhite quail,
mallard ducks >2000 mg/kg. LC50 (8 d) for
bobwhite quail >5200 ppm. Fish LC50 (96
h) for rainbow trout and common carp
>100 mg/l. Daphnia LC50 (48 h) 87 mg/l.
Algae LC50 (72 h) for Scenedesmus
subspicatus 47.1 mg/l; LC50 (5 d) for
Selenastrum capricornutum 21.7 mg/l.
Bees LD50 (48 h) (oral) >117 mg/bee;
(contact) >200 mg/bee. Worms LC50 (14
d) for Eisenia foetida 1098 mg/kg soil.
Other beneficial spp. Harmless to
Aleochara bilineata, Poecilus cupreus,
Typhlodromus pyri, Orius insidiosus,
Aphidius colemani, Aphidius matricariae,
Chrysoperla carnea.
2. Can Endeavor be used in greenhouses?
YES
3. What is the active ingredient in Endeavor?
Pymetrozine
Molecular
Structure
NOMENCLATURE
Common name pymetrozine (BSI, pa E-ISO)
IUPAC name (E)-4,5-dihydro-6-methyl-4-(3pyridylmethyleneamino)-1,2,4-triazin-3(2H)one
Chemical Abstracts name (E)-4,5-dihydro-6methyl-4-[(3-pyridinylmethylene)amino]-1,2,4triazin-3(2H)-one
CAS RN [123312-89-0] Development codes
CGA 215944 (Ciba-Geigy)
4. What is the formulation?
Water Dispersable Granule
Mix with water
5. What is the warning statement?
Danger – most toxic
Warning – moderate toxicity
Caution – low toxicity
6. Who makes the product?
http://www.syngenta.com
7. What is the EPA Registration Number?
No. 100-913
Using sound science as a
compass, EPA’s mission is
to protect you, your
family, and the
environment from
potential risks from
pesticides and toxic
chemicals. We also work
to prevent pollution
before it begins. This
reduces waste, saves
energy and natural
resources, and leaves our
homes, schools and
workplaces cleaner and
safer.
8. What do you do if you get endeavor in
your eyes?
Rinse eyes with water for 15-20 minutes.
Call doctor.
9. If someone swallows some Endeavor
should you induce vomiting?
NO
This can make things worse.
10. Can Endeavor be absorbed
through the skin?
YES
11. What protective clothing should be
worn when applying Endeavor?
•
•
•
•
•
Long sleeved shirt
Long pants
Chemical resistant gloves
Shoes
Socks
12. What should you do after using
Endeavor before eating or drinking?
Wash your hands
13. If something goes wrong when
someone uses this product, what liability
does the Syngenta Company have?
None
This means if something goes wrong when you use
the product Syngenta will not pay for any of the
damages.
14. What is the REI (Restricted
Entry Interval) for Endeavor?
12 Hours
15. What does REI mean?
The time people need to
stay out of a treated area.
16. What does PPE mean?
Personal Protective Equipment
17. What are the 2 main insects that
Endeavor controls?
Aphids
White Flies
18. What is the mode of action for Endeavor?
Stops the insects from feeding.
Paralyzed by Endeavor
19. How toxic is Endeavor to
beneficial insects?
Low Toxicity
20. Is Endeavor suitable to use
in an IPM program? Why?
Yes.
Because it has low toxicity to
beneficial insects.
21. What does phytotoxicity mean?
How toxic a chemical is to plants
22. Does Endeavor have any
phytotoxicity issues?
No
23. What is the rate of application
for whiteflies and aphids?
2.5 to 5.0 oz. per 100 gallon of water
24. Using the higher rate, how much
Endeavor is need per gallon of water?
5.0 oz. / 100 gal. water =
.05 oz. per gallon
25. How much Endeavor would be
needed for a 25 gallon sprayer?
.05 oz. X 25 = 1.25 oz.
26. At normal insect pressure, how
often can you spray Endeavor?
Every 14 days
27. What is a surfactant?
Product the makes the insecticide
stick to the plants better.