Postgraduate course
Advanced Immunology
UvA Sanquin VU
AMSTERDAM
26 January – 6 February 2015
PhD course Advanced Immunology
The post graduate course Advanced Immunology is inspired by the interest of the immunological
research of the Academic Medical Center of the University of Amsterdam, the Free University Amsterdam
and Sanquin Blood Supply (formerly known as the Central Laboratory of Blood Transfusion).
The course is strictly meant for PhD students working on projects that require substantial knowledge of
principles in immunology. The course is NOT allowed for senior scientists, post-docs, technicians,
analytical chemists, doctor researcher or other researchers that are not involved in a PhD project. It is
advised to attend this course in the first year of the PhD project.
The aim of the course is to further extend the knowledge on recent developments in immunology and to
contribute to insight in scientific questions and approaches in immunological research.
Topics include: molecules (MHC, antigen receptors, co-stimulatory molecules, adhesion molecules),
mediators (cytokines, chemokines, hormones) and cells (T and B lymphocytes, antigen-presenting cells,
innate cells) involved in immune responses; antigen-processing; regulation of immune responses; effector
mechanisms; infectious diseases, cancer, autoimmunity and allergy. Participants of the course should
have a good basic knowledge of immunology (Cuby, Janeway, Parham) such as obtained during
graduate training.
In the morning, lectures will be given on selected topics. In the afternoon, more active participation of the
PhD students is asked in discussions on selective immunological items.
Number of participants is limited to 60.
Period:
January 26 – February 6, 2015 (two weeks)
Venue:
first week:
second week:
VU University Medical Center
De Boelelaan 1117, Amsterdam, the Netherlands
Sanquin
Plesmanlaan 125, Amsterdam, the Netherlands
Registration:
You can register online at www.vumc.nl/advancedimmunology
Costs:
PhD students (strictly for UvA/AMC, Sanquin, VU/VUmc) 275 Euro
Others
800 Euro
th
Cancellation of your registration may only be done in writing at the latest December 19 , 2014.
th
We will refund the amount due except Euro 35,- administration fee. After December 19 , no
amount will be refunded.
Course Committee :
 Martijn Nolte (Dept. of Hematopoiesis Sanquin; 020-512 3377)
 Bianca Blom (Dept. Cell Biology and Histology AMC; 020 5668105)
 Wendy Unger (Dept Molecular Cell Biology and Immunology, VU University Medical Center;
020 4448142)
Organisation and information:
VU University Medical Center
VUmc Academy
P.O. Box 7057, 1007 MB Amsterdam
Tel. 020-4448444; E-mail: paog@vumc.nl
________________Program Advanced Immunology 2015
1st week: The Immune System
Location: VUmc*
Monday 26-1-2015
Introduction
0900 Introduction: aim and scope
Martijn Nolte, Wendy Unger
0945 Basic Immunology: repeat Janeway chapter 1-10
Martijn Nolte
1030 Coffee / tea
1045 Basic Immunology
Martijn Nolte
1215 Lunch
1300 Do you know how to cook?
Derk Amsen
1500
1700 Social program: De Kookfabriek (workshop How to Cook)
2100
Tuesday 27-1-2015
Innate Immunity
0900 Complement
0945 TLR
1030 Coffee / tea
1045 Macrophages
1130 Granulocytes
1215 lunch
Molecular and cellular processes
1300 Glycosylation and Immune regulation
1400 Dendritic cells and their recognition molecules
1600 End
Wednesday 28-1-2015
0900 T cell development / thymus
1030 Coffee / tea
1045 BCR and TCR
1215 Lunch
1300 NK cells
1400 Monocyte subsets and cardiovascular disease
1600
Cees van Kooten
Alex de Vos
Jörg Hamann
Marjolein van Egmond
Wendy Unger
Theo Geijtenbeek
Bianca Blom
Jannie Borst
Jeroen van Bergen
Menno de Winther
End
Thursday 29-1-2015
900
Gene regulation and protein expression
1030 Coffee / tea
1045 Epigenetic regulation
1130 Genetic engineering
1215 Lunch
1300 Autophagy
1400 MHC and antigen presentation
1600 End
Friday 30-1-2015
0900 Lymphoid organ development
0945 Leukocyte recirculation
(Coffee / tea break at 1030)
1130 Leukocyte – endothelial cell interaction
1215 Lunch
1300 Guest lecture “D6 chemokine blocker”
1600 End
* Faculty of Medicine, Van der Boechorststraat 7, Amsterdam
Peter van den Elsen
Peter van den Elsen
Robbert Spaapen
Carla Ribeiro
Jacques Neefjes
Reina Mebius
Martijn Nolte
Peter Hordijk
Gerry Graham
2nd week: The Immune system in action
Monday 2-2-2015
0900 T cell differentiation
1030 Coffee/tea
1045 T cell activation and polarization
1215 Lunch
1300 Effector T cell formation
1430 Masterclass
1600 End
Location: Sanquin, Gehoorzaal*
Derk Amsen
Esther de Jong
Matthew Krummel
Tuesday 3-2-2015
0900 Innate lymphoid cells and intestinal homeostasis Tom Cupedo
1030 Coffee
1045 Treg cells and mucosal immune regulation
Janneke Samsom
1215 Lunch
1300
1400
1600
Neuroimmune regulation
The gut microbiota in health and disease
End
Wouter de Jonge
Joost Wiersinga
Wednesday 4-2-2015
0900 Immune modulation by helminthes. A novel class of
helminth-induced regulators: regulatory B cells
1030 Coffee / tea
1045 Bacterial immune escape
1130 Apoptosis
1215 Lunch
1300
1430
1445
1615
Allergy
Coffee / tea
Viral Infection and inflammation
End
*Sanquin, Plesmanlaan 125, Amsterdam
Suzan Rooijakkers
Eric Eldering
Edward Knol
René Lutter
Thursday 5-2-2015
0900 B cell responses
1030 Coffee / tea
1045 Rheumatoid Arthritis and Spondyloarthritis
1215 Lunch
1300 B cells in pathology
1400 HIV
1600 End
Friday 6-2-2015
0900 Immunotherapy
1030 Coffee / tea
1045 Graft versus host disease
1215 Lunch
1300 The Immunology game
1430 Evaluation, drinks & snacks
Hermelijn Smits
Marieke van Ham
Dominique Baeten
Rien van Oers
José Borghans
Thorbald van Hall
Mette Hazenberg
Wendy Unger, Bianca Blom and Martijn Nolte