SAFETY DATA SHEET
Version 6.4
Revision Date 06/06/2020
Print Date 11/19/2020
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1
1.2
Product identifiers
:
Product Number
Brand
CAS-No.
: 133248
: Aldrich
: 39416-48-3
Relevant identified uses of the substance or mixture and uses advised against
Identified uses
1.3
1.4
Pyridinium tribromide
Product name
: Laboratory chemicals, Synthesis of substances
Details of the supplier of the safety data sheet
Company
: Sigma-Aldrich Inc.
3050 Spruce Street
ST. LOUIS MO 63103
UNITED STATES
Telephone
Fax
: +1 314 771-5765
: +1 800 325-5052
Emergency telephone number
Emergency Phone #
: 800-424-9300 CHEMTREC (USA) +1-703527-3887 CHEMTREC (International) 24
Hours/day; 7 Days/week
SECTION 2: Hazards identification
2.1
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Skin corrosion (Category 1B), H314
Serious eye damage (Category 1), H318
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2
GHS Label elements, including precautionary statements
Pictogram
Signal word
Danger
Hazard statement(s)
H314
Causes severe skin burns and eye damage.
Aldrich - 133248
The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
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H335
May cause respiratory irritation.
Precautionary statement(s)
P260
Do not breathe dust or mist.
P264
Wash skin thoroughly after handling.
P271
Use only outdoors or in a well-ventilated area.
P280
Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P301 + P330 + P331
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353
IF ON SKIN (or hair): Take off immediately all contaminated
clothing. Rinse skin with water/ shower.
P304 + P340 + P310
IF INHALED: Remove person to fresh air and keep comfortable
for breathing. Immediately call a POISON CENTER/ doctor.
P305 + P351 + P338 +
IF IN EYES: Rinse cautiously with water for several minutes.
P310
Remove contact lenses, if present and easy to do. Continue
rinsing. Immediately call a POISON CENTER/ doctor.
P363
Wash contaminated clothing before reuse.
P403 + P233
Store in a well-ventilated place. Keep container tightly closed.
P405
Store locked up.
P501
Dispose of contents/ container to an approved waste disposal
plant.
2.3
Hazards not otherwise classified (HNOC) or not covered by GHS
Lachrymator.
SECTION 3: Composition/information on ingredients
3.1
Substances
Synonyms
: Pyridine perbromide hydrobromide
Pyridinium bromide perbromide
Pyridine hydrobromide perbromide
Formula
: C5H5N·HBr·Br2
Molecular weight
CAS-No.
EC-No.
: 319.82 g/mol
: 39416-48-3
: 254-446-8
Component
Classification
Concentration
Skin Corr. 1B; Eye Dam.
1; STOT SE 3; H314,
H318, H335
<= 100 %
pyridinium bromide perbromide
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures
4.1
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of
dangerous area.
Aldrich - 133248
The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
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If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of
water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a
physician.Continue rinsing eyes during transport to hospital.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse
mouth with water. Consult a physician.
4.2
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3
Indication of any immediate medical attention and special treatment needed
No data available
SECTION 5: Firefighting measures
5.1
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen bromide gas
Combustible.
5.3
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4
Further information
No data available
SECTION 6: Accidental release measures
6.1
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist
or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing
dust.
For personal protection see section 8.
6.2
Environmental precautions
Do not let product enter drains.
6.3
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in
suitable, closed containers for disposal.
6.4
Reference to other sections
For disposal see section 13.
Aldrich - 133248
The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
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SECTION 7: Handling and storage
7.1
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Further processing
of solid materials may result in the formation of combustible dusts. The potential for
combustible dust formation should be taken into consideration before additional processing
occurs.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
7.2
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
7.3
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection
8.1
Control parameters
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
8.2
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands
before breaks and at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and
approved under appropriate government standards such as NIOSH (US) or EN
166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact
with this product. Dispose of contaminated gloves after use in accordance with
applicable laws and good laboratory practices. Wash and dry hands.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail
sales@kcl.de, test method: EN374
Aldrich - 133248
The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
Page 4 of 9
If used in solution, or mixed with other substances, and under conditions which
differ from EN 374, contact the supplier of the CE approved gloves. This
recommendation is advisory only and must be evaluated by an industrial hygienist
and safety officer familiar with the specific situation of anticipated use by our
customers. It should not be construed as offering an approval for any specific use
scenario.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must
be selected according to the concentration and amount of the dangerous substance
at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a fullface particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as
a backup to engineering controls. If the respirator is the sole means of protection,
use a full-face supplied air respirator. Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US) or CEN
(EU).
Control of environmental exposure
Do not let product enter drains.
SECTION 9: Physical and chemical properties
9.1
Information on basic physical and chemical properties
a)
Appearance
Form: solid
b)
Odour
No data available
c)
Odour Threshold
No data available
d)
pH
No data available
e)
Melting
point/freezing point
No data available
f)
Initial boiling point
and boiling range
No data available
g)
Flash point
No data available
h)
Evaporation rate
No data available
i)
Flammability (solid,
gas)
No data available
j)
Upper/lower
flammability or
explosive limits
No data available
k)
Vapour pressure
No data available
l)
Vapour density
No data available
m) Relative density
No data available
n)
Water solubility
No data available
o)
Partition coefficient:
n-octanol/water
No data available
p)
Auto-ignition
temperature
No data available
Aldrich - 133248
The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
Page 5 of 9
9.2
q)
Decomposition
temperature
No data available
r)
Viscosity
No data available
s)
Explosive properties
No data available
t)
Oxidizing properties
No data available
Other safety information
No data available
SECTION 10: Stability and reactivity
10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen
oxides (NOx), Hydrogen bromide gas
Other decomposition products - No data available
In the event of fire: see section 5
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute toxicity
Skin corrosion/irritation
Serious eye damage/eye irritation
Causes serious eye damage.
Respiratory or skin sensitisation
Germ cell mutagenicity
Carcinogenicity
IARC:
No component of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
NTP:
No component of this product present at levels greater than or equal to 0.1% is
identified as a known or anticipated carcinogen by NTP.
OSHA:
No component of this product present at levels greater than or equal to 0.1% is
on OSHA’s list of regulated carcinogens.
Aldrich - 133248
The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
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Reproductive toxicity
Specific target organ toxicity - single exposure
May cause respiratory irritation.
Specific target organ toxicity - repeated exposure
Aspiration hazard
Additional Information
RTECS: Not available
Cough, Shortness of breath, Headache, Nausea, Vomiting
SECTION 12: Ecological information
12.1 Toxicity
12.2 Persistence and degradability
12.3 Bioaccumulative potential
12.4 Mobility in soil
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
12.6 Other adverse effects
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a
licensed professional waste disposal service to dispose of this material. Dissolve or mix
the material with a combustible solvent and burn in a chemical incinerator equipped with
an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.
SECTION 14: Transport information
DOT (US)
UN number: 3261 Class: 8
Packing group: II
Proper shipping name: Corrosive solid, acidic, organic, n.o.s. (pyridinium bromide
perbromide)
Reportable Quantity (RQ):
Poison Inhalation Hazard: No
IMDG
UN number: 3261
Class: 8
Packing group: II
Aldrich - 133248
The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
EMS-No: F-A, S-B
Page 7 of 9
Proper shipping name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (pyridinium bromide
perbromide)
IATA
UN number: 3261 Class: 8
Packing group: II
Proper shipping name: Corrosive solid, acidic, organic, n.o.s. (pyridinium bromide
perbromide)
SECTION 15: Regulatory information
SARA 302 Components
This material does not contain any components with a section 302 EHS TPQ.
SARA 313 Components
This material does not contain any chemical components with known CAS numbers that
exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section
313.
SARA 311/312 Hazards
Acute Health Hazard
Massachusetts Right To Know Components
No components are subject to the Massachusetts Right to Know Act.
No components are subject to the Massachusetts Right to Know Act.
Pennsylvania Right To Know Components
pyridinium bromide perbromide
New Jersey Right To Know Components
pyridinium bromide perbromide
CAS-No.
39416-48-3
Revision Date
CAS-No.
39416-48-3
Revision Date
SECTION 16: Other information
Further information
Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies
for internal use only.
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any
damage resulting from handling or from contact with the above product. See
www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional
terms and conditions of sale.
The branding on the header and/or footer of this document may temporarily not visually
match the product purchased as we transition our branding. However, all of the
Aldrich - 133248
The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
Page 8 of 9
information in the document regarding the product remains unchanged and matches the
product ordered. For further information please contact mlsbranding@sial.com.
Version: 6.4
Revision Date: 06/06/2020
Aldrich - 133248
The life science business of Merck KGaA, Darmstadt, Germany
operates as MilliporeSigma in the US and Canada
Print Date: 11/19/2020
Page 9 of 9