1590 –invented microscope
Dutch spectacle makers
Zaccharias Janssen and
Hans Lipperhey are noted as
the first men to develop the
concept of the compound
microscope.
1609 - First device known as
microscope
Galileo Galilei built his
'occhiolino' in 1609, and
Faber was the first to name the
'microscope' from the Greek
'micron' (small) and 'skopein'
(to look at). Essentially a
modified telescope, Galileo's
microscope used a bi-concave
eyepiece and bi-convex
objective lens to provide up to
30 times magnification.
1665 – First use of term
‘cells’
English physicist Robert Hooke
publishes Micrographia, in
which he coins the term
‘cells’ when describing
tissue. The book includes
drawings of hairs on a nettle
and the honeycomb structure
of cork. He uses a simple,
single-lens microscope
illuminated by a candle.
1676 – Living cells first seen
Antonie van Leeuwenhoek
builds a simple microscope with
one lens to examine blood,
yeast and insects. He is the first
to describe cells and bacteria.
He invents new methods for
making lenses that allow for
magnifications of up to 270
times.
1830 – Spherical aberration
solved
Joseph Jackson Lister reduces
spherical aberration (which
produces imperfect images) by
using several weak lenses
together at certain distances to
give good magnification
without blurring the image.
1874 – Abbe equation
Ernst Abbe writes a
mathematical formula that
correlates resolving power to
the wavelength of light. Abbe’
s formula makes it possible to
calculate the theoretical
maximum resolution of a
microscope.
1931 – Transmission electron
microscope
Ernst Ruska and Max Knoll
design and build the first
transmission electron
microscope (TEM), based on an
idea of Leo Szilard. The electron
microscope depends on
electrons, not light, to view an
object. Modern TEMs can
visualise objects as small as the
diameter of an atom.
1942 – Scanning electron
microscope
Ernst Ruska builds the first
scanning electron microscope
(SEM), which transmits a beam
of electrons across the surface
of a specimen.
1838- All plants are made of
cells
German botanist Matthias
Schleiden concluded that all
plants are made of cells.
1839 - New cells are produced
from existing cells
German
physician,
Rudolf
Virchow, known as "the father
of modern pathology" and
founder of social medicine.
Rudolf concluded that new cells
can only be produced from the
division of existing cells.