:http://www.taiwanheadache.com.tw/
104
1
內
Transcranial direct current stimulation (tDCS)
啟
!
Transcranial direct current stimulation(tDCS
tDCS
(transcranial direct current stimulation, tDCS)
(
1-2mA)
(neuromodulation)
(Kuo, Paulus et al. 2013)
(Bindman, Lippold et al. 1964)
Nitsche
tDCS
(neuronal excitability)
(Nitsche and Paulus 2000)
(axonal membrane)
transcranial magnetic stimulation (TMS) (Pashut, Wolfus et al. 2011)
tDCS
(neuronal)
(resting membrane potential)
spontaneous firing
rates
(Zaghi, Acar et al. 2010)
anode
cathode tDCS
GABA
glutamate
(Stagg, Best et al. 2009)
tDCS
MEP
tDCS
(after-effects)
NMDA
(Nitsche and Paulus 2001)
tDCS
sham
TMS
!
(Gandiga, Hummel et al. 2006)
2!
!
tDCS
(Antal, Kriener et al. 2011) (Auvichayapat, Janyacharoen et al. 2012)
(Dasilva, Mendonca et al. 2012) (Pinchuk, Pinchuk et al. 2013) (Vigano,
D'Elia et al. 2013)
M1
V1
tDCS
central sensitization
M1
2006)
Fregni
anodal tDCS)
Antal
M1 anodal tDCS
central sensitization
central pain
M1
(Fregni, Boggio et al.
(poststroke pain syndrome)
fibromyalgia)
M1
tDCS
intracortical inhibition
central pain(Antal, Terney et al. 2010)
Auvichayapat
episodic migraine
20
20
M1 anodal tDCS(Auvichayapat, Janyacharoen et al. 2012)
abortive
4 8
4 8
12
chronic migraine
4
10
M1
anodal tDCS
(Dasilva, Mendonca et al.
2012)
M1
insula, thalamus, cingulate cortex
anodal tDCS
M1
pain
matrix
V1
tDCS
(evoked potential)
interictal period)
habituation (Ambrosini, de Noordhout
et al. 2003)
hyperexcitability
2012)
!
VEP
3!
(Goadsby
(Schoenen, Wang et
!
al. 1995)
BAEP) (Ambrosini, Rossi et al. 2003)
SSEP) (Coppola, Iacovelli et al. 2013)
VEP
(amplitude)
habituation
habituation
reduced
preactivation
(Coppola, Pierelli et al. 2007) (Coppola, Iacovelli et
al. 2013)
Vigano
anodal tDCS
episodic
migraneurs without aura (MoA) V1
(Vigano, D'Elia et al. 2013)
8
2
tDCS
tDCS
tDCS
4.8
tDCS
VEP
tDCS
habituation
(sham)
V1
cathodal tDCS
6
3
tDCS
—
Antal
cathodal tDCS
V1
(Antal, Kriener et al. 2011)
2
tDCS
2
V1
tDCS
(polarity)
tDCS
tDCS
tDCS
tDCS
(Martelletti, Jensen et al. 2013)
anodal tDCS
aftereffects
(Nitsche, Fricke et al. 2003) Propanolol
anodal cathodal
tDCS
aftereffects
(Nitsche, Grundey et al.
2004)
NMDA
tDCS aftereffects
NMDA
memantine NMDA
tDCS
!
4!
!
(Nitsche, Jaussi et al. 2004)
tDCS
cathodal tDCS
aftereffects
!
5!
Aura
anodal
!
Ambrosini,!A.,!A.!M.!de!Noordhout,!et!al.!(2003).!"Electrophysiological!studies!in!migraine:!a!comprehensive!
review!of!their!interest!and!limitations."!Cephalalgia!:!an!international!journal!of!headache!23#Suppl#1:!13J
31.!
Ambrosini,!A.,!P.!Rossi,!et!al.!(2003).!"Lack!of!habituation!causes!high!intensity!dependence!of!auditory!evoked!
cortical!potentials!in!migraine."!Brain!:!a!journal!of!neurology!126(Pt!9):!2009J2015.!
Antal,!A.,!N.!Kriener,!et!al.!(2011).!"Cathodal!transcranial!direct!current!stimulation!of!the!visual!cortex!in!the!
prophylactic!treatment!of!migraine."!Cephalalgia!:!an!international!journal!of!headache!31(7):!820J828.!
Antal,!A.,!D.!Terney,!et!al.!(2010).!"Anodal!transcranial!direct!current!stimulation!of!the!motor!cortex!ameliorates!
chronic!pain!and!reduces!short!intracortical!inhibition."!Journal!of!pain!and!symptom!management!39(5):!
890J903.!
Auvichayapat,!P.,!T.!Janyacharoen,!et!al.!(2012).!"Migraine!prophylaxis!by!anodal!transcranial!direct!current!
stimulation,!a!randomized,!placeboJcontrolled!trial."!Journal!of!the!Medical!Association!of!Thailand!=!
Chotmaihet!thangphaet!95(8):!1003J1012.!
Bindman,!L.!J.,!O.!C.!Lippold,!et!al.!(1964).!"The!Action!of!Brief!Polarizing!Currents!on!the!Cerebral!Cortex!of!the!
Rat!(1)!during!Current!Flow!and!(2)!in!the!Production!of!LongJLasting!afterJEffects."!The!Journal!of!
physiology!172:!369J382.!
Coppola,!G.,!E.!Iacovelli,!et!al.!(2013).!"Electrophysiological!correlates!of!episodic!migraine!chronification:!
evidence!for!thalamic!involvement."!The!journal!of!headache!and!pain!14:!76.!
Coppola,!G.,!F.!Pierelli,!et!al.!(2007).!"Is!the!cerebral!cortex!hyperexcitable!or!hyperresponsive!in!migraine?"!
Cephalalgia!:!an!international!journal!of!headache!27(12):!1427J1439.!
Dasilva,!A.!F.,!M.!E.!Mendonca,!et!al.!(2012).!"tDCSJinduced!analgesia!and!electrical!fields!in!painJrelated!neural!
networks!in!chronic!migraine."!Headache!52(8):!1283J1295.!
Fregni,!F.,!P.!S.!Boggio,!et!al.!(2006).!"A!shamJcontrolled,!phase!II!trial!of!transcranial!direct!current!stimulation!
for!the!treatment!of!central!pain!in!traumatic!spinal!cord!injury."!Pain!122(1J2):!197J209.!
Gandiga,!P.!C.,!F.!C.!Hummel,!et!al.!(2006).!"Transcranial!DC!stimulation!(tDCS):!a!tool!for!doubleJblind!shamJ
controlled!clinical!studies!in!brain!stimulation."!Clinical!neurophysiology!:!official!journal!of!the!International!
Federation!of!Clinical!Neurophysiology!117(4):!845J850.!
Goadsby,!P.!J.!(2012).!"Pathophysiology!of!migraine."!Annals!of!Indian!Academy!of!Neurology!15(Suppl!1):!S15J
22.!
Kuo,!M.!F.,!W.!Paulus,!et!al.!(2013).!"Therapeutic!effects!of!nonJinvasive!brain!stimulation!with!direct!currents!
(tDCS)!in!neuropsychiatric!diseases."!NeuroImage.!
Martelletti,!P.,!R.!H.!Jensen,!et!al.!(2013).!"Neuromodulation!of!chronic!headaches:!position!statement!from!the!
European!Headache!Federation."!The!journal!of!headache!and!pain!14:!86.!
Nitsche,!M.!A.,!K.!Fricke,!et!al.!(2003).!"Pharmacological!modulation!of!cortical!excitability!shifts!induced!by!
transcranial!direct!current!stimulation!in!humans."!The!Journal!of!physiology!553(Pt!1):!293J301.!
Nitsche,!M.!A.,!J.!Grundey,!et!al.!(2004).!"Catecholaminergic!consolidation!of!motor!cortical!neuroplasticity!in!
humans."!Cerebral!cortex!14(11):!1240J1245.!
Nitsche,!M.!A.,!W.!Jaussi,!et!al.!(2004).!"Consolidation!of!human!motor!cortical!neuroplasticity!by!DJcycloserine."!
Neuropsychopharmacology!:!official!publication!of!the!American!College!of!Neuropsychopharmacology!
29(8):!1573J1578.!
Nitsche,!M.!A.!and!W.!Paulus!(2000).!"Excitability!changes!induced!in!the!human!motor!cortex!by!weak!
transcranial!direct!current!stimulation."!The!Journal!of!physiology!527#Pt#3:!633J639.!
Nitsche,!M.!A.!and!W.!Paulus!(2001).!"Sustained!excitability!elevations!induced!by!transcranial!DC!motor!cortex!
stimulation!in!humans."!Neurology!57(10):!1899J1901.!
Pashut,!T.,!S.!Wolfus,!et!al.!(2011).!"Mechanisms!of!magnetic!stimulation!of!central!nervous!system!neurons."!
PLoS!computational!biology!7(3):!e1002022.!
Pinchuk,!D.,!O.!Pinchuk,!et!al.!(2013).!"Clinical!effectiveness!of!primary!and!secondary!headache!treatment!by!
transcranial!direct!current!stimulation."!Frontiers!in!neurology!4:!25.!
Schoenen,!J.,!W.!Wang,!et!al.!(1995).!"Potentiation!instead!of!habituation!characterizes!visual!evoked!potentials!
in!migraine!patients!between!attacks."!European!journal!of!neurology!:!the!official!journal!of!the!European!
Federation!of!Neurological!Societies!2(2):!115J122.!
Stagg,!C.!J.,!J.!G.!Best,!et!al.!(2009).!"PolarityJsensitive!modulation!of!cortical!neurotransmitters!by!transcranial!
stimulation."!The!Journal!of!neuroscience!:!the!official!journal!of!the!Society!for!Neuroscience!29(16):!5202J
5206.!
Vigano,!A.,!T.!S.!D'Elia,!et!al.!(2013).!"Transcranial!Direct!Current!Stimulation!(tDCS)!of!the!visual!cortex:!a!proofJ
ofJconcept!study!based!on!interictal!electrophysiological!abnormalities!in!migraine."!The!journal!of!
headache!and!pain!14(1):!23.!
Zaghi,!S.,!M.!Acar,!et!al.!(2010).!"Noninvasive!brain!stimulation!with!lowJintensity!electrical!currents:!putative!
mechanisms!of!action!for!direct!and!alternating!current!stimulation."!The!Neuroscientist!:!a!review!journal!
bringing!neurobiology,!neurology!and!psychiatry!16(3):!285J307.!
!
6!
北北區頭痛讀讀書會
親愛的醫師 您好:
很榮幸能邀請您參參加"北北區頭痛讀讀書會"(會議議程如下表)
衷心地期盼透過本次學術會議的交流流，對於頭痛之治療療能有所裨益益。
竭誠地邀請您，並感謝您的支持!
祝
醫 安
時間：104 年年 1 月 18 日 (星期日) 09:00~ 11:35
地點：老老爺大飯飯店 B1 會議廳(台北北市中山北北路路二段 37 之一號)
時間
主題
演講者
座長
09:00~09:05
Opening
王署君 醫師
陽明大學
09:05~09:45
Post-lumbar puncture-imaging
finding
王嚴鋒 醫師
台北北榮民總醫院
陳威宏 醫師
新光醫院
09:45~10:25
Case presentation
王署君 醫師
陽明大學
吳進安 醫師
關渡醫院
10:25~10:35
Break
10:35~11:15
Triptan treatment sharing
王凱震 醫師
振興醫院
黃子洲 醫師
活水診所
11:15~11:30
Discussion
ALL
王博仁 醫師
活水診所
11:30~11:35
Closing
陳威宏 醫師
新光醫院
主辦單位：台灣頭痛學會 Taiwan Headache Society
協辦單位：葛蘭蘭素史克藥廠
親愛的醫師 您好:
很榮幸能邀請您參參加"中區頭痛專家讀讀書會"(會議議程如下表)
衷心地期盼透過本次學術會議的交流流，對於頭痛之治療療能有所裨益益。
竭誠地邀請您，並感謝您的支持!
祝
醫 安
時間：104 年年 1 月 18 日(星期日)下午 15:30~18:30
地點：台中市台灣大道二段 285 號 21 樓樓 A 室(英才路路與台灣大道口)
服務電話：04-23197077
時
間
15:30~15:35
題
目
演
講
者
Opening
主 持 人
光田醫院
楊鈞百 醫師
15:35~16:20
16:20~17:05
Migraine and sleep disorders
Transcrainial direct current
stimulation and its
活水診所
活水診所
黃子洲醫師
王博仁院長
中國醫藥大學
秘書長
陳睿正醫師
劉劉子洋
application on headache
17:05~17:45
17:45~18:15
Big data and clinical
research
Discussion
新樓樓醫院
台北北榮民總醫院
謝鎮陽醫師
王署君 教授
楊鈞百、黃子洲、陳
睿正、謝鎮陽、王博
仁、王署君
18:15~18:30
Closing
陳威宏理理事長
神神經學會積分點數數:2.66 學分
家庭醫學積分點數數:申請中
主辦單位：台灣頭痛學會 Taiwan Headache Society
協辦單位：葛蘭蘭素史克藥廠
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http://arch2014.com/ or http://www.archchiangmai.com
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