Treatment of Common Conditions

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Treatment of Common

Conditions

Kenneth Brummel-Smith, MD

Charlotte Edwards Maguire Professor of Geriatrics

Florida State University College of Medicine

Common Conditions and Aging

Hypertension

Diabetes

High cholesterol

Arthritis

Osteoporosis

Dementia

Falls

Parkinson’s

Heart failure

Stroke

Cancer

Influenza & pneumonia

Depression

Anxiety

Sleep disorders

GERD

Arthritis

 Multiple pain problems – low back, hip, knee, ankles, hands

 Treatments

Tylenol equal to Celebrex and NSAID in studies

Lower rate of GI bleeding and kidney damage

Glucosamine (Rotta-brand - Dona)

Possibly ginger

 Exercise provides greatest benefits in function

 Arthroscopy not beneficial

Osteoporosis

 USPSTF recommends screening

 Fracture risk should be calculated (FRAX)

 Exercise is the mainstay of treatment

 Calcium, (and maybe vitamin D) - initial treatment

 Medical treatments likely help high risk or very low bone density patients

 If treatment is taken, 5 years is likely enough

Mild Cognitive Impairment

 Memory loss that is measurable but does not affect function

 Drugs for dementia do not prevent dementia or improve memory in MCI

 Exercise, Mediterranean diet, possibly mental games

Dementia

 Many types – Alzheimer’s, vascular, Lewy body, frontotemporal

 Prevention – exercise, alcohol, Med diet

 Get a detailed diagnosis – rule out other things

 Medications usually not helpful (common side effects)

 Small benefits from a huge number of complimentary medicines

Falls

 6 th leading cause of death over age 65

 Medications often the cause – all drugs that act on the central nervous system, heart drugs

 Exercise is mainstay of prevention and treatment

 Emphasize strength and balance

 Tai Chi most effective intervention

Heart Failure

 #1 cause of death in people over age 65

Self-management skills significantly decrease hospital admissions

Know your “ejection fraction”

 Exercise is the most common forgotten treatment (cardiac rehabilitation)

Stroke

#3 cause of death in people over age 65

Acute thrombolysis? (“clot busting”)

Red score on NNT – all positive studies were drug-company funded, all negative studies were not

High risk of hemorrhage

3 hour window

 Aspirin also not recommended for prevention

Cancer

 All cancers are different

 Second opinion recommended

 Discuss the actual experience of treatment

 Always include palliative care – symptom control

Influenza & Pneumonia

 Annual flu shot, one-time pneumovax shot

 Personal benefit – lower risk of serious infection and death

 Community benefit – reduce spread

 Prior worries of swine flu (Guillean-Barre) have not been seen in many years

Depression

 Get an accurate diagnosis (PHQ-9 or Geriatric

Depression Scale)

 3 equally effective treatments:

Exercise

Cognitive-behavioral therapy

Medications

 Combination of them more effective than one

 9 months of treatment after resolution, then attempt taper off medications

Anxiety

 Sometimes depression can present as anxiety

 Best treatment is exercise, mindfulness meditation or other means of stress reduction, massage, and cognitive-behavioral therapy

 Medications as a last resort

All increase risk of falls and confusion

SSRI rather than a benzodiazepine

Sleep Disorders

 Most common problem is lack of sleep

Sleep apnea – daytime drowsiness, snoring, snorting, waking up with headache, high blood pressure

Weight loss, exercise, “sleep hygiene”

 A sleep study can confirm it

 CPAP effective if basic interventions fail

GERD

 Proton pump inhibitors (omeprazole) are effective but should not be used indefinitely

 No difference between types – buy the cheapest

 H2 blockers (ranitidine) can do as good sometimes and has less risk over time

 Once a course has been completed (2-3 weeks) taper off and use as needed

 Lifestyle modifications help

GERD - Lifestyle

 Avoid aggravating foods – acidic, alcohol, caffeine, chocolate, onions, garlic

 Avoid large meals

 Medications – calcium channel blockers, nitrates, sedatives

Stop smoking

Don’t lie down after eating, raise bed

 Lose weight

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