LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.C.A. DEGREE EXAMINATION - COMPUTER APP.
FOURTH SEMESTER – APRIL 2012
CA 5952 - BIO INFORMATICS
Date : 23-04-2012
Time : 9:00 - 12:00
Dept. No.
Max. : 100 Marks
PART – A
Answer all questions:
10 * 2 =20
1. What is the use of NCBI?
2. What are the Applications of Bio informatics?
3. Give an example for Protein sequence Databases.
4. Define topology
5. Elucidate the main functions of Physical Mapping.
6. What is Portal?
7. Define FASTA format
8. What is the use of PDB?
9. What are the different levels of Protein Structures?
10. What is the use of Entrez?
PART – B
Answer all questions:
5 * 8 =40
11. a) Describe the Automated gene sequencing with a neat diagram.
(or)
b) Discuss the data and Meta data for neurofibromatosis.
12. a) Explain the Data models used in Bioinformatics.
(or)
b) Discuss Packet Communication in Network.
13. a) Write short notes on Protein data bank.
(or)
b) Explain any one of the Visualization technique.
14. a) Explain Pair wise sequence Alignment of nucleotide sequence data
(or)
b) Write short notes on Python tool.
15. a) Explain the component of Modeling and Simulation process.
(or)
b) Compare Synchronous and Asynchronous communication.
PART –C
Answer any two questions:
2 * 20 =40
(Q. No 16 is Compulsory)
16. Discuss the Central dogma of Bioinformatics (20 marks)
17. a. Discuss the PKE encryption algorithm.
b. Explain the NCBI Entrez system.
18. a. How are the Data Mining methods used in Bio informatics data bases?
Explain it.
b. Discuss the Applications of Statistics in Bioinformatics.
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