LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – BIOMED.INSTRUMENTATION SC.
THIRD SEMESTER – April 2009
CU 11
BI 3806 - TECHNICAL PATHOLOGY
Date & Time: 23/04/2009 / 1:00 - 4:00 Dept. No.
Max. : 100 Marks
SECTION-A
Answer ALL the questions
(10 x 2 = 20 Marks)
1. Define Lipofuscin
2. Mention the purpose of tissue fixation?
3. What is Xeroderma pigmentosum?
4. Differentiate hyperplasia from metaplasia.
5. What is Pyknosis?
6. Name the factors that increase the risk of folliculities.
7. Categorize the staining methods.
8. What is Pityriasis Alba?
9. Define Ochronosis.
10. Write the different types of herpes virus.
SECTION –B
Answer any FOUR the questions
(4 x 10 = 40 Marks)
11. Discuss the four basic types of melanoma and add a note on its diagnosis and treatment
of melanoma.
12. Which is the staining method introduced by Yasuma & Ichikawa? Explain the exact
protocol in detail.
13. Write notes on intracellular accumulation of exogenous pigments.
14. Enumerate the problems encountered during section cutting.
15. Explain in detail molecular mechanism of apoptosis.
16. Write notes on PAS Technique and Cryostat
SECTION-C
Answer any TWO the questions
(2 x 20= 40 Marks)
17. Fatty metamorphosis is the intracellular accumulation of neutral fat within
parenchymal cell. Substanciate.
18. Write down the steps of Paraffin embedding technique for section cutting with
suitable diagrams.
19. Explain the sequence of events in the pathogenesis of irreversible cell injury with
Ischaemia.
20. Comment on: a) Sakaguchi method b) Millon’s Reaction c) Oil Red O d) Alcian Blue.
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