SUPPLEMENTARY MATERIAL
To:
Brain Structure & Function
Title:
ABNORMAL PROCESSING OF DEONTOLOGICAL GUILT IN OBSESSIVE-COMPULSIVE DISORDER
Authors:
Barbara Basile1,2 PhD, Francesco Mancini2 MD, Emiliano Macaluso1 PhD, Carlo Caltagirone3,4 MD, Marco Bozzali1
MD.
Figure 1. FMRI Paradigm.
The timing of each event in each trial is illustrated schematically (modified from Basile et al.2011). Each trial included
the presentation of an emotional or neutral face, followed by a contextual sentence. The content of the sentence leads to
two types of guilt (deontological and altruistic) and two control conditions (anger and sadness). Subjects were asked to
observe each face and to imagine that an external person was experiencing that specific emotion directed toward
themselves. Then, a short sentence representing a inner dialogue in response to the specific facial expression was
shown. At the end of each trial (face + sentence), subjects were asked to indicate, in a forced yes/no choice, whether
they experienced guilt. Two examples are illustrated showing a trial with emotional face plus sentence inducing
deontological guilt, and a trial with emotional face plus sentence inducing altruistic guilt.