UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM BENZOATE
Table of Contents
Valid for:
2 years from approval
Page
1. Chemical Product
2. Composition and Information on Ingredients
3. Hazards Identification
4. First Aid Measures
5. Fire and Explosion Data
6. Accidental Release Measures
7. Handling and Storage
8. Exposure Controls/ Personal Protection
9. Physical and Chemical Properties
10. Stability and Reactivity Data
11. Toxicological Information
12. Ecological Information
13. Disposal Considerations
14. References
15. Appendices
16. Revision History
Page 1 of 9 Ref. No.
MSDS /PD/9_01
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UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM BENZOATE
Ref. No.
MSDS /PD/9_01
Valid for:
2 years from approval
Chemical Product
1.
Product Name: Sodium benzoate
Chemical name: Benzoic acid, sodium salt
Synonyms: Antimol, Benzoate of soda, Sodium benzoic acid, Benzoate sodium.
Chemical Formula: C7H502Na
2.
Composition and Information on Ingredients
Composition: Sodium benzoate 100% by weight
Toxicological Data on Ingredients: Sodium benzoate: ORAL (LD50): Acute: 4070 mg/kg
(Rat). 1600 mg/kg [Mouse]. 2000 mg/kg [Rabbit].
3.
Hazards Identification
Potential Acute Health Effects: Hazardous in case of skin and eye contact acting as an
irritant. Hazardous in case of inhalation. Slightly hazardous in case of ingestion.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: N/A
MUTAGENIC EFFECTS: N/A
TERATOGENIC EFFECTS: N/A
DEVELOPMENTAL TOXICITY: Classified as a toxin to the female reproductive system.
SUSPECTED to act as a toxin to the male reproductive system. May cause damage to the
reproductive system, blood, the liver and the central nervous system. Repeated or prolonged
exposure to the substance can produce target organ damage.
Page 2 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
4.
SODIUM BENZOATE
Ref. No.
MSDS /PD/9_01
Valid for:
2 years from approval
First Aid Measures
General measures: Use proper personal protective equipment.
Skin contact: Immediately flush skin with plenty of water. Apply an emollient on the irritated
area. Remove contaminated clothes and shoes. Wash clothing and clean shoes before reuse.
Seek medical attention.
Serious skin contact: Wash affected area with a disinfectant soap, and cover the area with an
antibacterial cream if necessary. Seek medical attention.
Eye contact: Check for and remove any contact lenses. Immediately flush eyes with plenty of
cold water for at least 15 minutes, lifting lower and upper eyelids occasionally. Seek medical
attention.
Ingestion: Do not induce emesis unless told to do so by medical personnel. Never give
anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or
waistband. Get medical attention if symptoms appear.
Serious indigestion: N/A
Inhalation: Remover to fresh air. If person is not breathing, give artificial respiration. If
person is finding it difficult to breathe, give oxygen. Seek medical attention.
Serious inhalation: N/A
Page 3 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
5.
SODIUM BENZOATE
Ref. No.
MSDS /PD/9_01
Valid for:
2 years from approval
Fire and Explosion Data
Flammability of the Product: May be combustible at high temperatures.
Auto-Ignition Temperature: N/A
Flash points: N/A
Flammable limits: N/A
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in
presence of heat. Non-flammable in the presence of shocks. Explosion Hazards in Presence of Various Substances: Risks of explosion of the product in
presence of mechanical impact: Not available. Slightly explosive in presence of open flames
and sparks.
Fire fighting media and Instructions:
- Small fire: Use dry chemical powder.
- Large fire: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: When heated to decomposition it emits acrid fumes and
disodium oxide.
Special Remarks on Explosion Hazards: Fine dust dispersed in air in sufficient
concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Page 4 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
6.
SODIUM BENZOATE
Ref. No.
MSDS /PD/9_01
Valid for:
2 years from approval
Accidental Release Measures
NB: Wear appropriate protective equipment/clothing including gloves before removing
any spills.
Small spill: Sweep up, absorb spill using appropriate tools in order to place material into a
convenient waste disposal container. Clean area by spreading water over contaminated surface
and dispose of according to local authority requirements.
Large spill: Use a shovel to place material into a convenient waste disposal container. Clean
area by spreading water over contaminated surface and allow to evacuate through the sanitary
system.
7.
Handling and Storage
Precautions: Keep container under lock and key, away from heat and away from sources of
ignition. Empty containers pose a fire risk; evaporate any residue under a fume hood. Ground
all equipment containing the material. Do not ingest or breathe any dust particles. Avoid
contact with eyes and skin. Use proper personal protective equipment. If ingested, seek
medical advice immediately and show the container or the label. Do not leave the substance
close to incompatibles such as oxidizing agents.
Storage: Keep container tightly closed in a cool, well-ventilated area. Hygroscopic substance.
Page 5 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM BENZOATE
Ref. No.
MSDS /PD/9_01
Valid for:
2 years from approval
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: N/A
Engineering Controls: Use process enclosures, local exhaust ventilation or other controls to
keep airborne levels below recommended exposure limits.
Personal Protection: Use chemical safety goggles, a full suit, a dust respirator, boots and
gloves. A self contained breathing apparatus should be used to avoid product inhalation.
Consult a specialist before handling this product as protective wear mentioned above might not
be protective enough.
9.
Physical and Chemical Properties
Physical state and appearance: White solid (granular solid, crystalline powder).
Odour: Odourless
Taste: Sweetish, astringent.
Molecular Weight: 144.11 g/mole
pH (1% solution/water): approx. 8
Boiling Point: N/A
Melting Point: >300°C (572°F)
Critical Temperature: N/A
Specific Gravity (Water = 1): 1.44
Vapour Pressure (mmHg): Not applicable.
Vapour Density: 4.97
Volatility: N/A
Odour Threshold: N/A
Water/Oil Distribution Coefficient: N/A
Ionicity (in Water): N/A
Dispersion Properties: See solubility in water.
Solubility: Easily soluble in cold and hot water.
Page 6 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM BENZOATE
Ref. No.
MSDS /PD/9_01
Valid for:
2 years from approval
Stability and Reactivity Data
10.
Stability: Stable
Corrosivity: Non-corrosive in presence of glass.
Instability temperature: N/A
Conditions of Instability: Excess heat, dust generation.
Incompatibles: Reactive with oxidizing agents.
Polymerization: Will not occur.
11.
Toxicological Information
Toxicity to animals: Acute oral toxicity (LD50): 1600 mg/kg
Effects on humans:
Acute potential health effects: Hazardous in case of skin and eye contact acting as an irritant.
Hazardous in case of inhalation. Slightly hazardous in case of ingestion.
Chronic potential health effects:
MUTAGENIC EFFECTS: N/A
TERATOGENIC EFFECTS: Classified POSSIBLE for human beings
DEVELOPMENTAL TOXICITY: Classified as a toxin to the female reproductive system.
SUSPECTED to act as a toxin to the male reproductive system. May cause damage to the
reproductive system, blood, the liver and the central nervous system.
Other information: N/A
12.
Ecological Information
Ecotoxicity: N/A Page 7 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
13.
SODIUM BENZOATE
Ref. No.
MSDS /PD/9_01
Valid for:
2 years from approval
Disposal Considerations
Waste Disposal: Observe all local regulations regarding disposal. Avoid unauthorised
disposal.
14.
References
-
Avogardo.chem.iastate.edu. Material Safety Data Sheet; Sodium Benzoate, MSDS
[Online].
2000
[cited
2012
May
18].
Available
from:
URL:
http://avogadro.chem.iastate.edu/MSDS/Na_benzoate.htm
-
Sciencelab.com. Material Safety Data Sheet; Sodium Benzoate, MSDS [Online]. 2010
[cited
2012
May
18].
Available
from:
URL:
http://www.sciencelab.com/msds.php?msdsId=9927413
15.
Appendices
N/A Page 8 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
16.
Ref. No.
MSDS /PD/9_01
Valid for:
2 years from approval
SODIUM BENZOATE
Revision History
Version Number Amendments/ Reasons for change
01
Initial Release
Page 9 of 9